SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ZBZ'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)
5ucd NAD(P)-DEPENDENT
BENZALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida)
4 / 8 PHE A 119
LEU A  57
GLY A 246
TYR A 121
NAP  A 501 (-4.5A)
None
None
ZBZ  A 249 ( 4.0A)
0.84A 1rmtC-5ucdA:
3.9
1rmtC-5ucdA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
5ucd NAD(P)-DEPENDENT
BENZALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida)
4 / 6 LEU A 125
ALA A  67
HIS A 418
TYR A 417
ZBZ  A 249 ( 4.6A)
None
None
None
1.15A 2dpzA-5ucdA:
undetectable
2dpzA-5ucdA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)
5ucd NAD(P)-DEPENDENT
BENZALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida)
4 / 8 ILE A 250
ALA A 399
PHE A 400
ALA A  71
ZBZ  A 249 ( 4.0A)
ZBZ  A 249 ( 4.3A)
None
None
0.86A 3hrdA-5ucdA:
undetectable
3hrdB-5ucdA:
undetectable
3hrdA-5ucdA:
23.48
3hrdB-5ucdA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)
5ucd NAD(P)-DEPENDENT
BENZALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida)
4 / 6 PHE A 406
HIS A 398
ILE A 250
TYR A 369
NAP  A 501 (-4.6A)
None
ZBZ  A 249 ( 4.0A)
None
1.39A 4o7gB-5ucdA:
undetectable
4o7gB-5ucdA:
20.70