SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ZAH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2bkl PROLYL ENDOPEPTIDASE
(Myxococcus
xanthus) 		3 / 3 GLY A 569
SER A 570
TRP A 574
 None
None
ZAH  A1533 (-3.7A)
 0.61A 4e7cD-2bklA:
undetectable		 4e7cD-2bklA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2bkl PROLYL ENDOPEPTIDASE
(Myxococcus
xanthus) 		5 / 12 GLY A 248
TYR A 453
SER A 533
TYR A 578
VAL A 619
 None
ZAH  A1533 (-4.5A)
ZAH  A1533 (-1.4A)
None
None
 1.16A 4ffwB-2bklA:
23.7		 4ffwB-2bklA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2bkl PROLYL ENDOPEPTIDASE
(Myxococcus
xanthus) 		4 / 5 HIS A 651
TYR A 530
GLY A 532
SER A 533
 ZAH  A1533 (-4.7A)
None
None
ZAH  A1533 (-1.4A)
 1.16A 4fu8A-2bklA:
undetectable		 4fu8A-2bklA:
16.26