SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'Z97'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q72_H_COCH401_1
(FAB M82G2, HEAVY
CHAIN
FAB M82G2, LIGHT
CHAIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 10 VAL A 130
GLY A 129
HIS A 182
TYR A 160
TYR A 157
 None
None
Z97  A 767 (-4.0A)
Z97  A 767 (-4.7A)
None
 1.46A 1q72H-3koyA:
2.2
1q72L-3koyA:
0.0		 1q72H-3koyA:
14.70
1q72L-3koyA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		3 / 3 HIS A 104
HIS A 158
MET A 106
 None
None
Z97  A 767 ( 4.1A)
 0.82A 3mihA-3koyA:
undetectable		 3mihA-3koyA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ALA A 181
VAL A 178
TYR A 157
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 0.94A 5eckA-3koyA:
undetectable		 5eckA-3koyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ALA A 181
VAL A 178
TYR A 157
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 0.95A 5eckD-3koyA:
undetectable		 5eckD-3koyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ALA A 181
VAL A 178
TYR A 157
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 1.00A 5eclA-3koyA:
undetectable		 5eclA-3koyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ALA A 181
VAL A 178
TYR A 157
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 1.00A 5ecoA-3koyA:
undetectable		 5ecoA-3koyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 CYH A 263
ILE A 330
HIS A 158
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 1.39A 5ocsA-3koyA:
10.0		 5ocsA-3koyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_C_ACTC402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 CYH A 263
ILE A 330
HIS A 158
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 1.39A 5ocsC-3koyA:
6.7		 5ocsC-3koyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 CYH A 263
SER A 265
HIS A 158
TYR A 160
 None
Z97  A 767 ( 4.6A)
None
Z97  A 767 (-4.7A)
 1.21A 5ycnA-3koyA:
undetectable		 5ycnA-3koyA:
16.12