SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'Z90'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LHU_A_ESTA301_1 (SEX HORMONE-BINDING GLOBULIN)	5mnw	GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 (Homo sapiens)	5 / 12	GLY A 71 PHE A 70 MET A 1 LEU A 142 ILE A 149	None None Z90 A 201 (-4.2A) None Z90 A 201 ( 4.2A)	1.26A	1lhuA-5mnwA: undetectable	1lhuA-5mnwA: 15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G1B_C_ECNC403_1 (FLAVOHEMOGLOBIN)	5mnw	GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 (Homo sapiens)	5 / 9	ILE A 66 PHE A 70 LEU A 67 VAL A 5 LEU A 9	None None None Z90 A 201 (-4.3A) None	1.25A	4g1bC-5mnwA: undetectable	4g1bC-5mnwA: 11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI504_0 (RNA POLYMERASE 3D-POL)	5mnw	GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 (Homo sapiens)	3 / 3	VAL A 146 GLY A 148 LYS A 151	Z90 A 201 ( 3.4A) None None	0.65A	4k50I-5mnwA: undetectable	4k50I-5mnwA: undetectable