SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'Z6X'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1375_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	3 / 3	LEU A 27 TYR A 26 GLN A 29	None Z6X A 401 ( 4.0A) None	0.73A	2wekA-5cb0A: 2.3	2wekA-5cb0A: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLA_B_CHDB501_0 (FERROCHELATASE, MITOCHONDRIAL)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	4 / 5	MET A 7 ARG A 22 ARG A 23 PRO A 141	None None Z6X A 401 ( 4.1A) None	1.17A	4klaB-5cb0A: 3.0	4klaB-5cb0A: 23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZJ8_A_SUVA2001_2 (HUMAN OX1R FUSION PROTEIN TO P.ABYSII GLYCOGEN SYNTHASE)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	4 / 6	TRP A 150 ILE A 265 HIS A 244 ILE A 238	Z6X A 401 (-4.0A) Z6X A 401 ( 4.1A) None None	0.97A	4zj8A-5cb0A: undetectable	4zj8A-5cb0A: 17.54