SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'YT3'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 2bec CALCINEURIN B
HOMOLOGOUS PROTEIN 2
(Homo
sapiens) 		4 / 8 ILE A 131
GLU A 163
ALA A 164
VAL A 172
 None
None
None
YT3  A1201 ( 4.8A)
 0.27A 1a29A-2becA:
6.2		 1a29A-2becA:
29.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3n9b PROBABLE
ATP-DEPENDENT DNA
LIGASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 135
ALA A 112
PHE A 130
LEU A 128
PHE A  51
 YT3  A 190 ( 2.2A)
None
None
None
None
 1.26A 1nw3A-3n9bA:
undetectable		 1nw3A-3n9bA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 1xkg MAJOR MITE FECAL
ALLERGEN DER P 1
(Dermatophagoides
pteronyssinus) 		5 / 11 LEU A 137
SER A 118
GLU A 139
VAL A 102
THR A 103
 None
None
YT3  A 401 (-2.8A)
None
None
 1.17A 3tbgA-1xkgA:
undetectable		 3tbgA-1xkgA:
18.79