SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'YE1'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RL8_A_RITA9001_1 (PROTEASE RETROPEPSIN)	2pg8	DPGC (Streptomyces toyocaensis)	6 / 12	GLY A 327 ALA A 329 VAL A 345 GLY A 295 ALA A 320 ILE A 346	YE1  A 997 (-3.4A) None None YE1  A 997 (-3.5A) None None	1.36A	1rl8A-2pg8A: undetectable	1rl8A-2pg8A: 13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8X_A_NIMA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	2pg8	DPGC (Streptomyces toyocaensis)	5 / 12	ARG A 332 ILE A 259 GLY A 327 ALA A 328 LEU A 331	None None YE1  A 997 (-3.4A) None None	1.24A	3n8xA-2pg8A: undetectable	3n8xA-2pg8A: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_A_RITA600_1 (CYTOCHROME P450 3A4)	2pg8	DPGC (Streptomyces toyocaensis)	5 / 12	PHE A 412 ILE A 324 ALA A 319 ILE A 294 ALA A 233	None OXY  A   3 (-3.9A) OXY  A   3 (-3.2A) YE1  A 997 ( 4.4A) YE1  A 997 (-3.9A)	0.94A	3nxuA-2pg8A: undetectable	3nxuA-2pg8A: 20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_B_RITB600_1 (CYTOCHROME P450 3A4)	2pg8	DPGC (Streptomyces toyocaensis)	5 / 12	PHE A 412 ILE A 324 ALA A 319 ILE A 294 ALA A 233	None OXY  A   3 (-3.9A) OXY  A   3 (-3.2A) YE1  A 997 ( 4.4A) YE1  A 997 (-3.9A)	0.92A	3nxuB-2pg8A: undetectable	3nxuB-2pg8A: 20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S56_A_ROCA201_2 (PROTEASE)	2pg8	DPGC (Streptomyces toyocaensis)	5 / 9	LEU A 240 GLY A 327 ILE A 325 ILE A 245 ILE A 235	None YE1  A 997 (-3.4A) None None YE1  A 997 (-3.3A)	1.12A	3s56B-2pg8A: undetectable	3s56B-2pg8A: 14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1475_0 (MJ0495-LIKE PROTEIN)	2pg8	DPGC (Streptomyces toyocaensis)	4 / 8	ILE A 245 ASP A 190 GLN A 299 GLY A 295	None None YE1  A 997 (-3.6A) YE1  A 997 (-3.5A)	0.83A	4ac9C-2pg8A: 2.0	4ac9C-2pg8A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJE_B_C2FB302_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	2pg8	DPGC (Streptomyces toyocaensis)	5 / 12	GLU A 189 MET A 197 ASP A 190 ASP A 184 SER A 232	YE1  A 997 (-2.3A) None None None None	1.28A	4djeB-2pg8A: undetectable	4djeB-2pg8A: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_A_STRA601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2pg8	DPGC (Streptomyces toyocaensis)	5 / 12	ALA A 329 ILE A 235 GLY A 297 ALA A 298 ILE A 346	None YE1  A 997 (-3.3A) None None None	0.86A	4nkxA-2pg8A: undetectable	4nkxA-2pg8A: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_C_STRC601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2pg8	DPGC (Streptomyces toyocaensis)	5 / 12	ALA A 329 ILE A 235 GLY A 297 ALA A 298 ILE A 346	None YE1  A 997 (-3.3A) None None None	0.80A	4nkxC-2pg8A: undetectable	4nkxC-2pg8A: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_D_STRD601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2pg8	DPGC (Streptomyces toyocaensis)	5 / 12	ALA A 329 ILE A 235 GLY A 297 ALA A 298 ILE A 346	None YE1  A 997 (-3.3A) None None None	0.81A	4nkxD-2pg8A: undetectable	4nkxD-2pg8A: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODO_B_FK5B203_2 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD)	2pg8	DPGC (Streptomyces toyocaensis)	3 / 3	ALA A 287 GLN A 299 GLY A 327	None YE1  A 997 (-3.6A) YE1  A 997 (-3.4A)	0.62A	4odoC-2pg8A: undetectable	4odoC-2pg8A: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R21_A_STRA601_1 (CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2)	2pg8	DPGC (Streptomyces toyocaensis)	4 / 6	ALA A 329 ILE A 235 GLY A 296 ILE A 346	None YE1  A 997 (-3.3A) YE1  A 997 (-3.6A) None	0.74A	4r21A-2pg8A: undetectable	4r21A-2pg8A: 23.78