SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'YCP'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	5yu1	LYSINE CYCLODEAMINASE (Streptomyces pristinaespirali s)	5 / 12	GLY A 303 HIS A 257 THR A 118 ALA A 208 ALA A 235	NAD A 402 ( 3.2A) None YCP A 403 (-4.0A) NAD A 402 (-4.4A) NA A 401 ( 4.1A)	0.96A	2gluB-5yu1A: 6.4	2gluB-5yu1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CFL_A_5CHA693_1 (LACTOTRANSFERRIN)	5yu1	LYSINE CYCLODEAMINASE (Streptomyces pristinaespirali s)	4 / 4	THR A 118 VAL A 233 GLY A 147 THR A 146	YCP A 403 (-4.0A) NAD A 402 (-4.2A) NAD A 402 (-3.3A) None	1.04A	3cflA-5yu1A: undetectable	3cflA-5yu1A: 13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA310_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	5yu1	LYSINE CYCLODEAMINASE (Streptomyces pristinaespirali s)	3 / 3	GLU A 259 HIS A 257 ARG A 49	None None YCP A 403 ( 3.5A)	0.84A	5uunA-5yu1A: undetectable	5uunA-5yu1A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA820_0 (GEPHYRIN)	5yu1	LYSINE CYCLODEAMINASE (Streptomyces pristinaespirali s)	4 / 5	GLU A 307 THR A 302 GLN A 260 MET A 65	None None None YCP A 403 (-3.8A)	1.45A	6fgdA-5yu1A: 2.7	6fgdA-5yu1A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2GLU_B_SAMB302_0","YCGJ","5yu1","LYSINE CYCLODEAMINASE","Streptomyces pristinaespiralis",5,"GLY A 303;HIS A 257;THR A 118;ALA A 208;ALA A 235","NAD A 402 ( 3.2A);None;YCP A 403 (-4.0A);NAD A 402 (-4.4A); NA A 401 ( 4.1A)","0.96A","2gluB-5yu1A:6.4",null],["3CFL_A_5CHA693_1","LACTOTRANSFERRIN","5yu1","LYSINE CYCLODEAMINASE","Streptomyces pristinaespiralis",4,"THR A 118;VAL A 233;GLY A 147;THR A 146","YCP A 403 (-4.0A);NAD A 402 (-4.2A);NAD A 402 (-3.3A);None","1.04A","3cflA-5yu1A:undetectable","2gluB-5yu1A:undetectable"],["5UUN_A_ACTA310_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","5yu1","LYSINE CYCLODEAMINASE","Streptomyces pristinaespiralis",3,"GLU A 259;HIS A 257;ARG A  49","None;None;YCP A 403 ( 3.5A)","0.84A","5uunA-5yu1A:undetectable","3cflA-5yu1A:13.31"],["6FGD_A_ACTA820_0","GEPHYRIN","5yu1","LYSINE CYCLODEAMINASE","Streptomyces pristinaespiralis",4,"GLU A 307;THR A 302;GLN A 260;MET A  65","None;None;None;YCP A 403 (-3.8A)","1.45A","6fgdA-5yu1A:2.7","5uunA-5yu1A:undetectable"]]