SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'XRS'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.25A 1uw6A-3zdhA:
32.2
1uw6B-3zdhA:
32.7
1uw6A-3zdhA:
99.05
1uw6B-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_B_NCTB1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 9 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.30A 1uw6B-3zdhA:
32.7
1uw6C-3zdhA:
32.4
1uw6B-3zdhA:
99.05
1uw6C-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.21A 1uw6D-3zdhA:
32.3
1uw6E-3zdhA:
32.4
1uw6D-3zdhA:
99.05
1uw6E-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_F_NCTF1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 10 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.25A 1uw6F-3zdhA:
32.3
1uw6G-3zdhA:
32.4
1uw6F-3zdhA:
99.05
1uw6G-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.25A 1uw6G-3zdhA:
32.4
1uw6H-3zdhA:
32.5
1uw6G-3zdhA:
99.05
1uw6H-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_H_NCTH1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 10 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.26A 1uw6H-3zdhA:
32.5
1uw6I-3zdhA:
32.5
1uw6H-3zdhA:
99.05
1uw6I-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_J_NCTJ1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 9 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.28A 1uw6F-3zdhA:
32.3
1uw6J-3zdhA:
32.5
1uw6F-3zdhA:
99.05
1uw6J-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_M_NCTM1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 10 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.34A 1uw6M-3zdhA:
32.3
1uw6N-3zdhA:
32.3
1uw6M-3zdhA:
99.05
1uw6N-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_N_NCTN1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 10 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.28A 1uw6N-3zdhA:
32.3
1uw6O-3zdhA:
32.4
1uw6N-3zdhA:
99.05
1uw6O-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_O_NCTO1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 9 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.26A 1uw6K-3zdhA:
32.4
1uw6O-3zdhA:
32.4
1uw6K-3zdhA:
99.05
1uw6O-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.25A 1uw6P-3zdhA:
32.2
1uw6Q-3zdhA:
32.5
1uw6P-3zdhA:
99.05
1uw6Q-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_Q_NCTQ1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 10 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.29A 1uw6Q-3zdhA:
32.5
1uw6R-3zdhA:
32.4
1uw6Q-3zdhA:
99.05
1uw6R-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_S_NCTS1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 10 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.24A 1uw6S-3zdhA:
32.4
1uw6T-3zdhA:
32.4
1uw6S-3zdhA:
99.05
1uw6T-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.30A 1uw6P-3zdhA:
32.2
1uw6T-3zdhA:
32.4
1uw6P-3zdhA:
99.05
1uw6T-3zdhA:
99.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WNC_A_TKTA300_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
6 / 10 TYR A  89
TRP A 143
TYR A 185
CSS A 187
CSS A 188
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.1A)
XRS  A 301 ( 3.8A)
XRS  A 301 ( 3.7A)
XRS  A 301 (-3.8A)
0.82A 2wncA-3zdhA:
25.2
2wncE-3zdhA:
18.4
2wncA-3zdhA:
34.65
2wncE-3zdhA:
34.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_A_ACHA1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 6 TYR A  89
TRP A 143
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.60A 2xz5A-3zdhA:
25.1
2xz5B-3zdhA:
25.1
2xz5A-3zdhA:
35.32
2xz5B-3zdhA:
35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 7 TYR A  89
TRP A 143
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.58A 2xz5B-3zdhA:
25.1
2xz5E-3zdhA:
25.2
2xz5B-3zdhA:
35.32
2xz5E-3zdhA:
35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.60A 2xz5A-3zdhA:
25.1
2xz5C-3zdhA:
25.2
2xz5A-3zdhA:
35.32
2xz5C-3zdhA:
35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.60A 2xz5C-3zdhA:
25.2
2xz5D-3zdhA:
25.2
2xz5C-3zdhA:
35.32
2xz5D-3zdhA:
35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 7 TYR A  89
TRP A 143
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.59A 2xz5D-3zdhA:
25.1
2xz5E-3zdhA:
25.2
2xz5D-3zdhA:
35.32
2xz5E-3zdhA:
35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 7 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.40A 3wipA-3zdhA:
32.4
3wipB-3zdhA:
32.2
3wipA-3zdhA:
100.00
3wipB-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.48A 3wipB-3zdhA:
32.2
3wipC-3zdhA:
32.4
3wipB-3zdhA:
100.00
3wipC-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.44A 3wipC-3zdhA:
32.4
3wipD-3zdhA:
32.4
3wipC-3zdhA:
100.00
3wipD-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.45A 3wipD-3zdhA:
32.4
3wipE-3zdhA:
32.6
3wipD-3zdhA:
100.00
3wipE-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.50A 3wipA-3zdhA:
32.4
3wipE-3zdhA:
32.6
3wipA-3zdhA:
100.00
3wipE-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 7 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.39A 3wipF-3zdhA:
32.0
3wipG-3zdhA:
33.0
3wipF-3zdhA:
100.00
3wipG-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.39A 3wipG-3zdhA:
33.0
3wipH-3zdhA:
32.1
3wipG-3zdhA:
100.00
3wipH-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_H_ACHH301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 9 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.42A 3wipH-3zdhA:
32.1
3wipI-3zdhA:
32.7
3wipH-3zdhA:
100.00
3wipI-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_I_ACHI301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 9 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.61A 3wipI-3zdhA:
32.7
3wipJ-3zdhA:
32.8
3wipI-3zdhA:
100.00
3wipJ-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.39A 3wipF-3zdhA:
32.0
3wipJ-3zdhA:
32.8
3wipF-3zdhA:
100.00
3wipJ-3zdhA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.44A 4aftD-3zdhA:
25.3
4aftE-3zdhA:
18.5
4aftD-3zdhA:
35.32
4aftE-3zdhA:
35.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.52A 4bqtC-3zdhA:
25.1
4bqtD-3zdhA:
25.0
4bqtC-3zdhA:
35.32
4bqtD-3zdhA:
35.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.44A 5kxiA-3zdhA:
22.4
5kxiB-3zdhA:
22.9
5kxiA-3zdhA:
19.07
5kxiB-3zdhA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.44A 5kxiD-3zdhA:
22.5
5kxiE-3zdhA:
22.8
5kxiD-3zdhA:
19.07
5kxiE-3zdhA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 8 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.49A 6cnjD-3zdhA:
20.2
6cnjE-3zdhA:
21.0
6cnjD-3zdhA:
19.17
6cnjE-3zdhA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_A_NCTA405_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
4 / 6 TYR A  89
TRP A 143
THR A 144
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 (-3.8A)
0.54A 6cnkA-3zdhA:
20.4
6cnkB-3zdhA:
14.2
6cnkA-3zdhA:
19.17
6cnkB-3zdhA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 7 TYR A  89
TRP A 143
CSS A 187
CSS A 188
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 3.8A)
XRS  A 301 ( 3.7A)
XRS  A 301 (-3.8A)
0.47A 6cnkB-3zdhA:
14.2
6cnkC-3zdhA:
20.7
6cnkB-3zdhA:
19.17
6cnkC-3zdhA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_D_NCTD401_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
3zdh ACETYLCHOLINE
BINDING PROTEIN

(Lymnaea
stagnalis)
5 / 9 TYR A  89
TRP A 143
THR A 144
TYR A 185
TYR A 192
None
XRS  A 301 (-3.6A)
XRS  A 301 ( 4.4A)
XRS  A 301 ( 4.1A)
XRS  A 301 (-3.8A)
0.57A 6cnkD-3zdhA:
20.5
6cnkE-3zdhA:
21.2
6cnkD-3zdhA:
19.17
6cnkE-3zdhA:
17.56