SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'XPE'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 3uwq OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE
(Vibrio
cholerae) 		4 / 5 PHE A  63
SER A  71
PHE A  58
ILE A 102
 None
XPE  A 233 (-4.1A)
None
None
 1.37A 2v0mD-3uwqA:
undetectable		 2v0mD-3uwqA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 3rwg MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS I
(Macaca
mulatta) 		3 / 3 ARG A 170
GLU A 163
TYR A   7
 XPE  A 277 (-3.1A)
XPE  A 277 ( 4.7A)
None
 0.90A 3k37B-3rwgA:
undetectable		 3k37B-3rwgA:
20.60