SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'XCA'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYN_A_1UNA1001_3 (PROTEASE RETROPEPSIN)	3up3	ACEDAF-12 (Ancylostoma ceylanicum)	3 / 3	ASP A 493 THR A 546 PRO A 547	None XCA  A 100 (-3.7A) XCA  A 100 (-4.8A)	0.69A	2pynB-3up3A: undetectable	2pynB-3up3A: 17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QAK_A_1UNA1001_4 (PROTEASE RETROPEPSIN)	3up3	ACEDAF-12 (Ancylostoma ceylanicum)	3 / 3	ASP A 493 THR A 546 PRO A 547	None XCA  A 100 (-3.7A) XCA  A 100 (-4.8A)	0.68A	2qakB-3up3A: undetectable	2qakB-3up3A: 15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_3 (PROTEASE)	3up3	ACEDAF-12 (Ancylostoma ceylanicum)	3 / 3	ASP A 493 THR A 546 PRO A 547	None XCA  A 100 (-3.7A) XCA  A 100 (-4.8A)	0.63A	3tkgD-3up3A: undetectable	3tkgD-3up3A: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNW_A_T3A502_1 (THYROID HORMONE RECEPTOR ALPHA)	3up3	ACEDAF-12 (Ancylostoma ceylanicum)	4 / 8	MET A 492 VAL A 494 THR A 495 ARG A 498	None XCA  A 100 ( 4.2A) XCA  A 100 (-3.0A) None	0.87A	4lnwA-3up3A: 20.2	4lnwA-3up3A: 23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YOA_A_017A100_1 (HIV-1 PROTEASE)	3up3	ACEDAF-12 (Ancylostoma ceylanicum)	4 / 6	ASP A 493 THR A 546 PRO A 547 THR A 548	None XCA  A 100 (-3.7A) XCA  A 100 (-4.8A) EDO  A 200 (-3.4A)	0.75A	4yoaA-3up3A: undetectable	4yoaA-3up3A: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_A_SAMA301_0 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	3up3	ACEDAF-12 (Ancylostoma ceylanicum)	5 / 12	GLY A 524 ARG A 605 ILE A 596 LEU A 529 LEU A 654	None None None XCA  A 100 (-4.3A) None	1.05A	5bw4A-3up3A: undetectable	5bw4A-3up3A: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC3_B_486B801_1 (GLUCOCORTICOID RECEPTOR)	3up3	ACEDAF-12 (Ancylostoma ceylanicum)	5 / 12	LEU A 664 GLY A 662 PHE A 665 MET A 492 LEU A 529	XCA  A 100 (-4.8A) None None None XCA  A 100 (-4.3A)	1.04A	5uc3B-3up3A: 16.9	5uc3B-3up3A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCY_A_DB8A401_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	3up3	ACEDAF-12 (Ancylostoma ceylanicum)	4 / 4	VAL A 669 LEU A 664 ASN A 490 ASP A 487	EDO  A 400 ( 3.7A) XCA  A 100 (-4.8A) None None	1.37A	5vcyA-3up3A: undetectable	5vcyA-3up3A: 20.25