SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'XAM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AJ6_A_NOVA1_1
(GYRASE)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		5 / 9 ASN A  49
ASP A  76
ARG A 138
ILE A  96
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.6A)
None
None
XAM  A2000 (-3.6A)
 1.45A 1aj6A-4urlA:
29.6		 1aj6A-4urlA:
42.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AJ6_A_NOVA1_1
(GYRASE)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		7 / 9 ASN A  49
GLU A  53
ASP A  76
ARG A  79
PRO A  82
ILE A  96
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.8A)
None
XAM  A2000 (-3.6A)
 0.71A 1aj6A-4urlA:
29.6		 1aj6A-4urlA:
42.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AJ6_A_NOVA1_1
(GYRASE)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		9 / 9 ASN A  54
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ALA A  98
ILE A 102
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 ( 3.8A)
XAM  A2000 (-4.5A)
XAM  A2000 (-3.8A)
 0.56A 1aj6A-4urmA:
29.9		 1aj6A-4urmA:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		7 / 12 ASP A  52
GLU A  53
ASP A  76
ARG A  79
ILE A  96
ARG A 138
THR A 168
 None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
None
None
XAM  A2000 (-3.6A)
 0.76A 1kijA-4urlA:
44.0		 1kijA-4urlA:
46.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		7 / 12 ASP A  52
GLU A  53
ASP A  76
ARG A  79
PRO A  82
ILE A  96
THR A 168
 None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.8A)
None
XAM  A2000 (-3.6A)
 0.71A 1kijA-4urlA:
44.0		 1kijA-4urlA:
46.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		8 / 12 ASP A  57
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ASP A  89
THR A 173
 None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
None
XAM  A2000 (-3.8A)
 0.91A 1kijA-4urmA:
28.7		 1kijA-4urmA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		9 / 12 ASP A  57
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ILE A 102
ARG A 144
THR A 173
 None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
None
XAM  A2000 (-3.8A)
 0.61A 1kijA-4urmA:
28.7		 1kijA-4urmA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		7 / 12 ASN A  49
GLU A  53
ASP A  76
ARG A  79
ALA A 122
ARG A 138
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 ( 4.3A)
None
XAM  A2000 (-3.6A)
 0.71A 1kijB-4urlA:
44.2		 1kijB-4urlA:
46.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		8 / 12 ASN A  49
GLU A  53
ASP A  76
ARG A  79
PRO A  82
ILE A  96
ALA A 122
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.8A)
None
XAM  A2000 ( 4.3A)
XAM  A2000 (-3.6A)
 0.79A 1kijB-4urlA:
44.2		 1kijB-4urlA:
46.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		9 / 12 ASN A  54
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ASP A  89
ILE A 102
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
None
XAM  A2000 (-4.5A)
XAM  A2000 (-3.8A)
 0.92A 1kijB-4urmA:
29.0		 1kijB-4urmA:
32.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		9 / 12 ASN A  54
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ILE A 102
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
None
XAM  A2000 (-3.8A)
 0.58A 1kijB-4urmA:
29.0		 1kijB-4urmA:
32.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		10 / 12 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
ILE A  96
ARG A 138
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
None
None
XAM  A2000 (-3.6A)
 0.63A 1s14A-4urlA:
24.7		 1s14A-4urlA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		10 / 12 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
PRO A  82
ILE A  96
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
XAM  A2000 (-4.8A)
None
XAM  A2000 (-3.6A)
 0.56A 1s14A-4urlA:
24.7		 1s14A-4urlA:
24.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ASP A  89
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
None
None
XAM  A2000 (-3.8A)
 0.81A 1s14A-4urmA:
25.3		 1s14A-4urmA:
37.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ILE A 102
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
None
XAM  A2000 (-3.8A)
 0.60A 1s14A-4urmA:
25.3		 1s14A-4urmA:
37.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		8 / 12 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
ARG A 138
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
None
 0.67A 1s14B-4urlA:
26.9		 1s14B-4urlA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		9 / 12 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
PRO A  82
ILE A  96
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
XAM  A2000 (-4.8A)
None
 0.56A 1s14B-4urlA:
26.9		 1s14B-4urlA:
24.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ALA A  98
ILE A 102
ARG A 144
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
XAM  A2000 ( 3.8A)
XAM  A2000 (-4.5A)
None
 0.67A 1s14B-4urmA:
27.4		 1s14B-4urmA:
37.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		8 / 12 ASN A  54
SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ASP A  89
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
None
 0.89A 1s14B-4urmA:
27.4		 1s14B-4urmA:
37.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		10 / 12 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
ILE A  96
ARG A 138
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
None
None
XAM  A2000 (-3.6A)
 0.67A 3lpsA-4urlA:
39.8		 3lpsA-4urlA:
35.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		10 / 12 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
PRO A  82
ILE A  96
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
XAM  A2000 (-4.8A)
None
XAM  A2000 (-3.6A)
 0.53A 3lpsA-4urlA:
39.8		 3lpsA-4urlA:
35.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ILE A 102
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
None
XAM  A2000 (-3.8A)
 0.64A 3lpsA-4urmA:
27.6		 3lpsA-4urmA:
30.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		8 / 12 SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ASP A  89
THR A 173
 XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
None
XAM  A2000 (-3.8A)
 1.01A 3lpsA-4urmA:
27.6		 3lpsA-4urmA:
30.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		4 / 8 ALA A  28
ASN A  54
ILE A  51
GLY A 127
 None
XAM  A2000 (-3.7A)
XAM  A2000 ( 4.2A)
None
 0.79A 4r20A-4urmA:
undetectable		 4r20A-4urmA:
19.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		10 / 11 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
PRO A  82
ILE A  96
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
XAM  A2000 (-4.8A)
None
XAM  A2000 (-3.6A)
 0.76A 4urnA-4urlA:
32.8		 4urnA-4urlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		10 / 11 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
MET A  81
PRO A  82
ILE A  96
ARG A 138
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.3A)
XAM  A2000 (-4.8A)
None
None
XAM  A2000 (-3.6A)
 0.79A 4urnA-4urlA:
32.8		 4urnA-4urlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 11 ASN A  54
SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ILE A 102
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
None
XAM  A2000 (-3.8A)
 0.60A 4urnA-4urmA:
30.3		 4urnA-4urmA:
58.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		10 / 11 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
PRO A  82
ILE A  96
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
XAM  A2000 (-4.8A)
None
XAM  A2000 (-3.6A)
 0.64A 4urnB-4urlA:
29.3		 4urnB-4urlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		9 / 11 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
MET A  81
ILE A  96
ARG A 138
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.3A)
None
None
XAM  A2000 (-3.6A)
 0.76A 4urnB-4urlA:
29.3		 4urnB-4urlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 11 ASN A  54
SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ILE A 102
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
None
XAM  A2000 (-3.8A)
 0.56A 4urnB-4urmA:
27.8		 4urnB-4urmA:
58.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		10 / 11 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
ARG A  79
MET A  81
PRO A  82
ILE A  96
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.3A)
XAM  A2000 (-4.8A)
None
XAM  A2000 (-3.6A)
 0.62A 4urnC-4urlA:
32.4		 4urnC-4urlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		8 / 11 ASN A  49
SER A  50
ASP A  52
GLU A  53
ASP A  76
MET A  81
ARG A 138
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
None
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.3A)
None
XAM  A2000 (-3.6A)
 0.70A 4urnC-4urlA:
32.4		 4urnC-4urlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 11 ASN A  54
SER A  55
ASP A  57
GLU A  58
ASP A  81
ARG A  84
PRO A  87
ILE A 102
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
None
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
None
XAM  A2000 (-3.8A)
 0.58A 4urnC-4urmA:
30.0		 4urnC-4urmA:
58.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		7 / 12 ASN A  49
SER A  50
GLU A  53
ASP A  76
ARG A  79
ILE A  96
ARG A 138
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
None
None
 0.68A 4uroA-4urlA:
29.8		 4uroA-4urlA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		7 / 12 ASN A  49
SER A  50
GLU A  53
ASP A  76
ARG A  79
PRO A  82
ILE A  96
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.8A)
None
 0.61A 4uroA-4urlA:
29.8		 4uroA-4urlA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		9 / 12 ASN A  54
SER A  55
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ASP A  89
SER A 128
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
None
XAM  A2000 ( 4.4A)
 0.90A 4uroA-4urmA:
32.9		 4uroA-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
GLN A  91
ILE A 102
SER A 128
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-3.2A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.4A)
 0.81A 4uroA-4urmA:
32.9		 4uroA-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ILE A 102
SER A 128
ARG A 144
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.4A)
None
 0.56A 4uroA-4urmA:
32.9		 4uroA-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		6 / 12 ASN A  49
SER A  50
GLU A  53
ASP A  76
ARG A  79
ARG A 138
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
None
 0.66A 4uroB-4urlA:
29.8		 4uroB-4urlA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		7 / 12 ASN A  49
SER A  50
GLU A  53
ASP A  76
ARG A  79
PRO A  82
ILE A  96
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.8A)
None
 0.63A 4uroB-4urlA:
29.8		 4uroB-4urlA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		9 / 12 ASN A  54
SER A  55
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ASP A  89
SER A 128
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
None
XAM  A2000 ( 4.4A)
 0.85A 4uroB-4urmA:
32.9		 4uroB-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
GLN A  91
ILE A 102
SER A 128
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-3.2A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.4A)
 0.79A 4uroB-4urmA:
32.9		 4uroB-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ILE A 102
SER A 128
ARG A 144
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.4A)
None
 0.52A 4uroB-4urmA:
32.9		 4uroB-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		5 / 12 ASN A  49
GLU A  53
ASP A  76
ARG A  79
ARG A 138
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
None
 0.72A 4uroC-4urlA:
30.0		 4uroC-4urlA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		6 / 12 ASN A  49
GLU A  53
ASP A  76
ARG A  79
PRO A  82
ILE A  96
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.8A)
None
 0.58A 4uroC-4urlA:
30.0		 4uroC-4urlA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		8 / 12 ASN A  54
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ASP A  89
SER A 128
 XAM  A2000 (-3.7A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
None
XAM  A2000 ( 4.4A)
 0.96A 4uroC-4urmA:
32.9		 4uroC-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		11 / 12 ASN A  54
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
GLN A  91
ALA A  98
ILE A 102
SER A 128
ARG A 144
 XAM  A2000 (-3.7A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-3.2A)
XAM  A2000 ( 3.8A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.4A)
None
 0.71A 4uroC-4urmA:
32.9		 4uroC-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		8 / 12 ASN A  49
SER A  50
GLU A  53
ASP A  76
ARG A  79
ILE A  96
ARG A 138
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
None
None
XAM  A2000 (-3.6A)
 0.74A 4uroD-4urlA:
29.6		 4uroD-4urlA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 4url DNA TOPOISOMERASE
IV, B SUBUNIT
(Staphylococcus
aureus) 		8 / 12 ASN A  49
SER A  50
GLU A  53
ASP A  76
ARG A  79
PRO A  82
ILE A  96
THR A 168
 XAM  A2000 (-3.9A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.1A)
XAM  A2000 (-3.6A)
XAM  A2000 (-3.7A)
XAM  A2000 (-4.8A)
None
XAM  A2000 (-3.6A)
 0.64A 4uroD-4urlA:
29.6		 4uroD-4urlA:
37.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		10 / 12 ASN A  54
SER A  55
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ASP A  89
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
None
None
XAM  A2000 (-3.8A)
 0.82A 4uroD-4urmA:
32.4		 4uroD-4urmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 4urm DNA GYRASE SUBUNIT B
(Staphylococcus
aureus) 		11 / 12 ASN A  54
SER A  55
GLU A  58
ASP A  81
ARG A  84
ILE A  86
PRO A  87
ILE A 102
SER A 128
ARG A 144
THR A 173
 XAM  A2000 (-3.7A)
XAM  A2000 (-3.3A)
XAM  A2000 (-2.6A)
XAM  A2000 (-3.4A)
XAM  A2000 (-3.6A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.9A)
XAM  A2000 (-4.5A)
XAM  A2000 ( 4.4A)
None
XAM  A2000 (-3.8A)
 0.49A 4uroD-4urmA:
32.4		 4uroD-4urmA:
100.00