SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'X6X'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5f8y GALNAC/GAL-SPECIFIC
LECTIN
(Crenomytilus
grayanus) 		3 / 3 HIS A  37
HIS A  16
MET A  40
 X6X  A 203 (-4.0A)
X6X  A 203 (-3.7A)
None
 0.91A 3mihA-5f8yA:
undetectable		 3mihA-5f8yA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5f8y GALNAC/GAL-SPECIFIC
LECTIN
(Crenomytilus
grayanus) 		3 / 3 HIS A 129
HIS A 108
MET A 132
 X6X  A 202 (-3.9A)
X6X  A 202 (-3.8A)
None
 0.92A 3mihA-5f8yA:
undetectable		 3mihA-5f8yA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 5f8y GALNAC/GAL-SPECIFIC
LECTIN
(Crenomytilus
grayanus) 		3 / 3 LYS A 110
VAL A 123
HIS A 125
 None
None
X6X  A 202 (-3.7A)
 1.23A 3tj7A-5f8yA:
undetectable		 3tj7A-5f8yA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 5f8y GALNAC/GAL-SPECIFIC
LECTIN
(Crenomytilus
grayanus) 		4 / 7 HIS A  33
ASP A  35
HIS A  16
PRO A  17
 X6X  A 203 (-3.7A)
X6X  A 203 (-3.6A)
X6X  A 203 (-3.7A)
None
 1.06A 4hvrA-5f8yA:
undetectable		 4hvrA-5f8yA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 5f8y GALNAC/GAL-SPECIFIC
LECTIN
(Crenomytilus
grayanus) 		4 / 7 HIS A 125
ASP A 127
HIS A 108
PRO A 109
 X6X  A 202 (-3.7A)
X6X  A 202 (-3.6A)
X6X  A 202 (-3.8A)
None
 1.07A 4hvrA-5f8yA:
undetectable		 4hvrA-5f8yA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5f8y GALNAC/GAL-SPECIFIC
LECTIN
(Crenomytilus
grayanus) 		4 / 4 LEU A  30
MET A  78
VAL A  79
ASN A  27
 None
None
None
X6X  A 201 ( 3.5A)
 1.48A 5b8iB-5f8yA:
undetectable		 5b8iB-5f8yA:
19.32