SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'WAQ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 5fll 6-CARBOXYHEXANOATE-C
OA LIGASE
(Bacillus
subtilis) 		4 / 7 ASP A 195
TYR A 199
ASP A 196
HIS A  26
 MG  A 704 (-2.7A)
WAQ  A 700 (-4.6A)
MG  A 704 (-2.6A)
PPV  A 701 (-3.8A)
 1.32A 1t03A-5fllA:
undetectable		 1t03A-5fllA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5fll 6-CARBOXYHEXANOATE-C
OA LIGASE
(Bacillus
subtilis) 		3 / 3 TRP A 119
VAL A 204
ARG A 213
 None
None
WAQ  A 700 (-3.8A)
 0.97A 3b0wA-5fllA:
undetectable		 3b0wA-5fllA:
19.86