SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'W4A'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWH_B_BAXB1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	6 / 12	ALA A 119 LYS A 121 GLU A 136 LEU A 140 LEU A 215 HIS A 223	W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) None None None	0.75A	1uwhB-5myvA: 19.7	1uwhB-5myvA: 23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZVA_A_1N1A513_1 (TYROSINE-PROTEIN KINASE LYN)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A 98 ALA A 119 LYS A 121 GLU A 136 VAL A 157 GLY A 181 LEU A 232 ALA A 540	W4A A 716 (-4.1A) W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) DMS A 717 (-4.3A) W4A A 716 (-3.8A) None DMS A 717 ( 4.5A)	1.03A	2zvaA-5myvA: 22.5	2zvaA-5myvA: 24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G5D_B_1N1B1_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	9 / 12	LEU A 98 VAL A 106 ALA A 119 LYS A 121 GLU A 136 VAL A 157 GLY A 181 LEU A 232 ALA A 540	W4A A 716 (-4.1A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) DMS A 717 (-4.3A) W4A A 716 (-3.8A) None DMS A 717 ( 4.5A)	1.10A	3g5dB-5myvA: 21.4	3g5dB-5myvA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GP0_A_NILA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	6 / 12	VAL A 106 ALA A 119 GLU A 136 LEU A 139 LEU A 140 HIS A 223	W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) DMS A 717 (-4.0A) None None None	0.99A	3gp0A-5myvA: 20.9	3gp0A-5myvA: 26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK3_B_0LIB2_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	5 / 12	ALA A 119 GLU A 136 VAL A 157 HIS A 223 ALA A 540	W4A A 716 ( 3.9A) DMS A 717 (-4.0A) DMS A 717 (-4.3A) None DMS A 717 ( 4.5A)	0.67A	3ik3B-5myvA: 19.8	3ik3B-5myvA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QLG_A_1N1A601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	9 / 12	LEU A 98 VAL A 106 ALA A 119 LYS A 121 GLU A 136 VAL A 157 GLY A 181 LEU A 232 ALA A 540	W4A A 716 (-4.1A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) DMS A 717 (-4.3A) W4A A 716 (-3.8A) None DMS A 717 ( 4.5A)	1.05A	3qlgA-5myvA: 20.8	3qlgA-5myvA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RGF_A_BAXA465_1 (CYCLIN-DEPENDENT KINASE 8)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	8 / 12	VAL A 106 ALA A 119 GLU A 136 LEU A 140 PHE A 177 LEU A 215 HIS A 223 ALA A 540	W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) DMS A 717 (-4.0A) None DMS A 717 ( 3.9A) None None DMS A 717 ( 4.5A)	0.64A	3rgfA-5myvA: 21.1	3rgfA-5myvA: 26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOS_A_0LIA1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	ALA A 119 LYS A 121 GLU A 136 LEU A 215 HIS A 223 LEU A 232 ALA A 540	W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) None None None DMS A 717 ( 4.5A)	0.79A	3zosA-5myvA: 12.7	3zosA-5myvA: 24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOS_B_0LIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	ALA A 119 LYS A 121 GLU A 136 LEU A 215 HIS A 223 LEU A 232 ALA A 540	W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) None None None DMS A 717 ( 4.5A)	0.83A	3zosB-5myvA: 12.7	3zosB-5myvA: 24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	ALA A 119 LYS A 121 GLU A 136 LEU A 140 HIS A 223 LEU A 232 ALA A 540	W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) None None None DMS A 717 ( 4.5A)	0.88A	4c8bA-5myvA: 19.9	4c8bA-5myvA: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	ALA A 119 LYS A 121 GLU A 136 LEU A 140 HIS A 223 LEU A 232 ALA A 540	W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) None None None DMS A 717 ( 4.5A)	0.85A	4c8bB-5myvA: 19.9	4c8bB-5myvA: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KS8_A_B49A701_1 (SERINE/THREONINE-PRO TEIN KINASE PAK 6)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	6 / 10	ALA A 119 VAL A 157 LEU A 180 GLY A 181 LEU A 232 ASP A 541	W4A A 716 ( 3.9A) DMS A 717 (-4.3A) W4A A 716 (-4.3A) W4A A 716 (-3.8A) None DMS A 717 (-4.3A)	0.99A	4ks8A-5myvA: 23.5	4ks8A-5myvA: 25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V01_A_0LIA1776_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	5 / 12	ALA A 119 GLU A 136 LEU A 215 HIS A 223 ALA A 540	W4A A 716 ( 3.9A) DMS A 717 (-4.0A) None None DMS A 717 ( 4.5A)	0.71A	4v01A-5myvA: 19.2	4v01A-5myvA: 24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V01_B_0LIB1770_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	5 / 12	ALA A 119 GLU A 136 LEU A 215 HIS A 223 ALA A 540	W4A A 716 ( 3.9A) DMS A 717 (-4.0A) None None DMS A 717 ( 4.5A)	0.67A	4v01B-5myvA: 19.6	4v01B-5myvA: 24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	6 / 12	GLY A 99 VAL A 106 ALA A 119 VAL A 157 PHE A 177 LEU A 232	W4A A 716 ( 4.0A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) DMS A 717 (-4.3A) DMS A 717 ( 3.9A) None	0.74A	5l2iA-5myvA: 14.6	5l2iA-5myvA: 26.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENT KINASE 6)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	6 / 12	GLY A 99 VAL A 106 ALA A 119 VAL A 157 PHE A 177 LEU A 232	W4A A 716 ( 4.0A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) DMS A 717 (-4.3A) DMS A 717 ( 3.9A) None	0.94A	5l2tA-5myvA: 14.5	5l2tA-5myvA: 26.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NNA_A_BZMA301_0 (ISATIN HYDROLASE A)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	5 / 12	LEU A 232 SER A 104 VAL A 106 GLY A 99 GLY A 101	None SO4 A 702 (-2.7A) W4A A 716 ( 4.7A) W4A A 716 ( 4.0A) SO4 A 702 (-3.3A)	1.24A	5nnaA-5myvA: undetectable	5nnaA-5myvA: 20.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	10 / 12	ARG A 96 LEU A 98 GLY A 99 VAL A 106 ALA A 119 PHE A 177 GLY A 181 VAL A 235 TYR A 239 ALA A 540	None W4A A 716 (-4.1A) W4A A 716 ( 4.0A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) DMS A 717 ( 3.9A) W4A A 716 (-3.8A) W4A A 716 ( 4.9A) W4A A 716 (-4.8A) DMS A 717 ( 4.5A)	0.46A	5xv7A-5myvA: 49.0	5xv7A-5myvA: 86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	ARG A 96 PHE A 177 GLY A 181 HIS A 182 VAL A 235 TYR A 239 ALA A 540	None DMS A 717 ( 3.9A) W4A A 716 (-3.8A) W4A A 716 ( 3.6A) W4A A 716 ( 4.9A) W4A A 716 (-4.8A) DMS A 717 ( 4.5A)	0.80A	5xv7A-5myvA: 49.0	5xv7A-5myvA: 86.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	6 / 12	LEU A 98 GLY A 99 VAL A 106 ALA A 119 PHE A 177 VAL A 240	W4A A 716 (-4.1A) W4A A 716 ( 4.0A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) DMS A 717 ( 3.9A) None	1.22A	5xv7A-5myvA: 49.0	5xv7A-5myvA: 86.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	LEU A 98 VAL A 106 ALA A 119 LYS A 121 GLU A 136 GLY A 181 LEU A 232	W4A A 716 (-4.1A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) W4A A 716 (-3.8A) None	1.05A	5y7zA-5myvA: 23.9	5y7zA-5myvA: 11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	LEU A 98 VAL A 106 ALA A 119 LYS A 121 GLU A 136 GLY A 181 LEU A 232	W4A A 716 (-4.1A) W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) W4A A 716 (-3.8A) None	1.05A	5y7zA-5myvA: 23.9	5y7zA-5myvA: 22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_A_STIA604_0 (TYROSINE-PROTEIN KINASE ABL1)	5myv	SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2 (Homo sapiens)	7 / 12	VAL A 106 ALA A 119 LYS A 121 GLU A 136 VAL A 157 LEU A 232 ALA A 540	W4A A 716 ( 4.7A) W4A A 716 ( 3.9A) SO4 A 702 (-3.3A) DMS A 717 (-4.0A) DMS A 717 (-4.3A) None DMS A 717 ( 4.5A)	0.99A	6hd4A-5myvA: 19.7	6hd4A-5myvA: 11.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UWH_B_BAXB1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",6,"ALA A 119;LYS A 121;GLU A 136;LEU A 140;LEU A 215;HIS A 223","W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);None;None;None","0.75A","1uwhB-5myvA:19.7",null],["2ZVA_A_1N1A513_1","TYROSINE-PROTEIN KINASE LYN","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",8,"LEU A  98;ALA A 119;LYS A 121;GLU A 136;VAL A 157;GLY A 181;LEU A 232;ALA A 540","W4A A 716 (-4.1A);W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);DMS A 717 (-4.3A);W4A A 716 (-3.8A);None;DMS A 717 ( 4.5A)","1.03A","2zvaA-5myvA:22.5","1uwhB-5myvA:23.59"],["3G5D_B_1N1B1_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",9,"LEU A  98;VAL A 106;ALA A 119;LYS A 121;GLU A 136;VAL A 157;GLY A 181;LEU A 232;ALA A 540","W4A A 716 (-4.1A);W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);DMS A 717 (-4.3A);W4A A 716 (-3.8A);None;DMS A 717 ( 4.5A)","1.10A","3g5dB-5myvA:21.4","2zvaA-5myvA:24.63"],["3GP0_A_NILA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 11","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",6,"VAL A 106;ALA A 119;GLU A 136;LEU A 139;LEU A 140;HIS A 223","W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);DMS A 717 (-4.0A);None;None;None","0.99A","3gp0A-5myvA:20.9","3g5dB-5myvA:23.44"],["3IK3_B_0LIB2_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",5,"ALA A 119;GLU A 136;VAL A 157;HIS A 223;ALA A 540","W4A A 716 ( 3.9A);DMS A 717 (-4.0A);DMS A 717 (-4.3A);None;DMS A 717 ( 4.5A)","0.67A","3ik3B-5myvA:19.8","3gp0A-5myvA:26.46"],["3QLG_A_1N1A601_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",9,"LEU A  98;VAL A 106;ALA A 119;LYS A 121;GLU A 136;VAL A 157;GLY A 181;LEU A 232;ALA A 540","W4A A 716 (-4.1A);W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);DMS A 717 (-4.3A);W4A A 716 (-3.8A);None;DMS A 717 ( 4.5A)","1.05A","3qlgA-5myvA:20.8","3ik3B-5myvA:21.48"],["3RGF_A_BAXA465_1","CYCLIN-DEPENDENT KINASE 8","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",8,"VAL A 106;ALA A 119;GLU A 136;LEU A 140;PHE A 177;LEU A 215;HIS A 223;ALA A 540","W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);DMS A 717 (-4.0A);None;DMS A 717 ( 3.9A);None;None;DMS A 717 ( 4.5A)","0.64A","3rgfA-5myvA:21.1","3qlgA-5myvA:23.44"],["3ZOS_A_0LIA1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",7,"ALA A 119;LYS A 121;GLU A 136;LEU A 215;HIS A 223;LEU A 232;ALA A 540","W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);None;None;None;DMS A 717 ( 4.5A)","0.79A","3zosA-5myvA:12.7","3rgfA-5myvA:26.29"],["3ZOS_B_0LIB1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",7,"ALA A 119;LYS A 121;GLU A 136;LEU A 215;HIS A 223;LEU A 232;ALA A 540","W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);None;None;None;DMS A 717 ( 4.5A)","0.83A","3zosB-5myvA:12.7","3zosA-5myvA:24.15"],["4C8B_A_0LIA1000_1","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",7,"ALA A 119;LYS A 121;GLU A 136;LEU A 140;HIS A 223;LEU A 232;ALA A 540","W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);None;None;None;DMS A 717 ( 4.5A)","0.88A","4c8bA-5myvA:19.9","3zosB-5myvA:24.15"],["4C8B_B_0LIB1000_1","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",7,"ALA A 119;LYS A 121;GLU A 136;LEU A 140;HIS A 223;LEU A 232;ALA A 540","W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);None;None;None;DMS A 717 ( 4.5A)","0.85A","4c8bB-5myvA:19.9","4c8bA-5myvA:22.60"],["4KS8_A_B49A701_1","SERINE\/THREONINE-PROTEIN KINASE PAK 6","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",6,"ALA A 119;VAL A 157;LEU A 180;GLY A 181;LEU A 232;ASP A 541","W4A A 716 ( 3.9A);DMS A 717 (-4.3A);W4A A 716 (-4.3A);W4A A 716 (-3.8A);None;DMS A 717 (-4.3A)","0.99A","4ks8A-5myvA:23.5","4c8bB-5myvA:22.60"],["4V01_A_0LIA1776_1","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",5,"ALA A 119;GLU A 136;LEU A 215;HIS A 223;ALA A 540","W4A A 716 ( 3.9A);DMS A 717 (-4.0A);None;None;DMS A 717 ( 4.5A)","0.71A","4v01A-5myvA:19.2","4ks8A-5myvA:25.30"],["4V01_B_0LIB1770_1","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",5,"ALA A 119;GLU A 136;LEU A 215;HIS A 223;ALA A 540","W4A A 716 ( 3.9A);DMS A 717 (-4.0A);None;None;DMS A 717 ( 4.5A)","0.67A","4v01B-5myvA:19.6","4v01A-5myvA:24.53"],["5L2I_A_LQQA900_1","CYCLIN-DEPENDENT KINASE 6","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",6,"GLY A  99;VAL A 106;ALA A 119;VAL A 157;PHE A 177;LEU A 232","W4A A 716 ( 4.0A);W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);DMS A 717 (-4.3A);DMS A 717 ( 3.9A);None","0.74A","5l2iA-5myvA:14.6","4v01B-5myvA:24.53"],["5L2T_A_6ZZA900_1","CYCLIN-DEPENDENT KINASE 6","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",6,"GLY A  99;VAL A 106;ALA A 119;VAL A 157;PHE A 177;LEU A 232","W4A A 716 ( 4.0A);W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);DMS A 717 (-4.3A);DMS A 717 ( 3.9A);None","0.94A","5l2tA-5myvA:14.5","5l2iA-5myvA:26.75"],["5NNA_A_BZMA301_0","ISATIN HYDROLASE A","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",5,"LEU A 232;SER A 104;VAL A 106;GLY A  99;GLY A 101","None;SO4 A 702 (-2.7A);W4A A 716 ( 4.7A);W4A A 716 ( 4.0A);SO4 A 702 (-3.3A)","1.24A","5nnaA-5myvA:undetectable","5l2tA-5myvA:26.75"],["5XV7_A_EMHA705_1","SERINE-ARGININE (SR) PROTEIN KINASE 1","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",10,"ARG A  96;LEU A  98;GLY A  99;VAL A 106;ALA A 119;PHE A 177;GLY A 181;VAL A 235;TYR A 239;ALA A 540","None;W4A A 716 (-4.1A);W4A A 716 ( 4.0A);W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);DMS A 717 ( 3.9A);W4A A 716 (-3.8A);W4A A 716 ( 4.9A);W4A A 716 (-4.8A);DMS A 717 ( 4.5A)","0.46A","5xv7A-5myvA:49.0","5nnaA-5myvA:20.91"],["5XV7_A_EMHA705_1","SERINE-ARGININE (SR) PROTEIN KINASE 1","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",7,"ARG A  96;PHE A 177;GLY A 181;HIS A 182;VAL A 235;TYR A 239;ALA A 540","None;DMS A 717 ( 3.9A);W4A A 716 (-3.8A);W4A A 716 ( 3.6A);W4A A 716 ( 4.9A);W4A A 716 (-4.8A);DMS A 717 ( 4.5A)","0.80A","5xv7A-5myvA:49.0","5xv7A-5myvA:86.25"],["5XV7_A_EMHA705_1","SERINE-ARGININE (SR) PROTEIN KINASE 1","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",6,"LEU A  98;GLY A  99;VAL A 106;ALA A 119;PHE A 177;VAL A 240","W4A A 716 (-4.1A);W4A A 716 ( 4.0A);W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);DMS A 717 ( 3.9A);None","1.22A","5xv7A-5myvA:49.0","5xv7A-5myvA:86.25"],["5Y7Z_A_IREA401_0","CYCLIN-G-ASSOCIATED KINASE","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",7,"LEU A  98;VAL A 106;ALA A 119;LYS A 121;GLU A 136;GLY A 181;LEU A 232","W4A A 716 (-4.1A);W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);W4A A 716 (-3.8A);None","1.05A","5y7zA-5myvA:23.9","5xv7A-5myvA:86.25"],["5Y7Z_A_IREA401_0","CYCLIN-G-ASSOCIATED KINASE","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",7,"LEU A  98;VAL A 106;ALA A 119;LYS A 121;GLU A 136;GLY A 181;LEU A 232","W4A A 716 (-4.1A);W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);W4A A 716 (-3.8A);None","1.05A","5y7zA-5myvA:23.9","5y7zA-5myvA:11.02"],["6HD4_A_STIA604_0","TYROSINE-PROTEIN KINASE ABL1","5myv","SRSF PROTEIN KINASE 2,SRSF PROTEIN KINASE 2","Homo sapiens",7,"VAL A 106;ALA A 119;LYS A 121;GLU A 136;VAL A 157;LEU A 232;ALA A 540","W4A A 716 ( 4.7A);W4A A 716 ( 3.9A);SO4 A 702 (-3.3A);DMS A 717 (-4.0A);DMS A 717 (-4.3A);None;DMS A 717 ( 4.5A)","0.99A","6hd4A-5myvA:19.7","5y7zA-5myvA:22.98"]]