SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'W01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	1qju	PROTEIN VP1 (Rhinovirus A)	5 / 12	LEU 1 181 ILE 1 122 ILE 1 236 LEU 1 217 THR 1 216	W01 17001 (-4.6A) W01 17001 ( 4.6A) W01 17001 ( 4.9A) W01 17001 (-4.2A) None	1.02A	2bdmA-1qju1: undetectable	2bdmA-1qju1: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L4D_A_TPFA490_1 (STEROL 14-ALPHA DEMETHYLASE)	1qju	PROTEIN VP1 (Rhinovirus A)	4 / 8	PHE 1 118 ALA 1 116 THR 1 208 MET 1 214	None None None W01 17001 (-4.1A)	0.71A	3l4dA-1qju1: undetectable	3l4dA-1qju1: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L4D_D_TPFD490_1 (STEROL 14-ALPHA DEMETHYLASE)	1qju	PROTEIN VP1 (Rhinovirus A)	4 / 8	PHE 1 118 ALA 1 116 THR 1 208 MET 1 214	None None None W01 17001 (-4.1A)	0.72A	3l4dD-1qju1: undetectable	3l4dD-1qju1: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_C_7V7C202_1 (ENDO-1,4-BETA-XYLANA SE A)	1qju	PROTEIN VP1 (Rhinovirus A)	4 / 8	THR 1 216 TYR 1 144 ARG 1 220 GLN 1 141	None W01 17001 (-4.0A) None None	1.28A	5tzoC-1qju1: undetectable	5tzoC-1qju1: 19.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BDM_A_TMIA502_1","CYTOCHROME P450 2B4","1qju","PROTEIN VP1","Rhinovirus A",5,"LEU 1 181;ILE 1 122;ILE 1 236;LEU 1 217;THR 1 216","W01 17001 (-4.6A);W01 17001 ( 4.6A);W01 17001 ( 4.9A);W01 17001 (-4.2A);None","1.02A","2bdmA-1qju1:undetectable",null],["3L4D_A_TPFA490_1","STEROL 14-ALPHA DEMETHYLASE","1qju","PROTEIN VP1","Rhinovirus A",4,"PHE 1 118;ALA 1 116;THR 1 208;MET 1 214","None;None;None;W01 17001 (-4.1A)","0.71A","3l4dA-1qju1:undetectable","2bdmA-1qju1:18.60"],["3L4D_D_TPFD490_1","STEROL 14-ALPHA DEMETHYLASE","1qju","PROTEIN VP1","Rhinovirus A",4,"PHE 1 118;ALA 1 116;THR 1 208;MET 1 214","None;None;None;W01 17001 (-4.1A)","0.72A","3l4dD-1qju1:undetectable","3l4dA-1qju1:18.06"],["5TZO_C_7V7C202_1","ENDO-1,4-BETA-XYLANASE A","1qju","PROTEIN VP1","Rhinovirus A",4,"THR 1 216;TYR 1 144;ARG 1 220;GLN 1 141","None;W01 17001 (-4.0A);None;None","1.28A","5tzoC-1qju1:undetectable","3l4dD-1qju1:18.06"]]