SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'VNL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 4eyg TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
(Rhodopseudomonas
palustris) 		3 / 3 ASP A 258
PHE A 225
ASN A 233
 None
VNL  A 401 ( 4.8A)
None
 0.87A 1sg9B-4eygA:
3.4		 1sg9B-4eygA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4eyg TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
(Rhodopseudomonas
palustris) 		4 / 6 GLY A 104
GLY A 229
PHE A 304
PHE A 145
 None
None
VNL  A 401 (-4.7A)
VNL  A 401 (-4.7A)
 1.01A 2qx6A-4eygA:
4.0
2qx6B-4eygA:
undetectable		 2qx6A-4eygA:
23.08
2qx6B-4eygA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 4eyg TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
(Rhodopseudomonas
palustris) 		4 / 8 ASP A 255
LEU A 147
GLY A 129
HIS A 276
 VNL  A 401 (-3.5A)
None
VNL  A 401 (-3.7A)
None
 1.03A 3af0A-4eygA:
undetectable		 3af0A-4eygA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 4eyg TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
(Rhodopseudomonas
palustris) 		5 / 12 ILE A 133
VAL A 125
GLY A 104
THR A 130
PRO A 175
 None
None
None
None
VNL  A 401 (-4.0A)
 0.87A 3s56A-4eygA:
undetectable		 3s56A-4eygA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 4eyg TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
(Rhodopseudomonas
palustris) 		4 / 7 GLY A 229
THR A  46
VAL A 226
HIS A 276
 None
VNL  A 401 (-3.9A)
None
None
 0.96A 4qwpB-4eygA:
undetectable		 4qwpB-4eygA:
22.16