SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'VN4'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 11 SER A  89
ARG A  94
ILE A 133
ALA A 135
ALA A 142
 None
ADP  A1001 ( 2.9A)
None
VN4  A1002 (-4.6A)
None
 1.26A 1jb0B-4dz6A:
undetectable		 1jb0B-4dz6A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 11 SER A  89
ILE A 133
ALA A 135
LEU A   9
ALA A 142
 None
None
VN4  A1002 (-4.6A)
None
None
 1.39A 1jb0B-4dz6A:
undetectable		 1jb0B-4dz6A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 11 SER A  89
ARG A  94
ILE A 133
ALA A 135
ALA A 142
 None
ADP  A1001 ( 2.9A)
None
VN4  A1002 (-4.6A)
None
 1.26A 3pcqB-4dz6A:
undetectable		 3pcqB-4dz6A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 11 SER A  89
ILE A 133
ALA A 135
LEU A   9
ALA A 142
 None
None
VN4  A1002 (-4.6A)
None
None
 1.38A 3pcqB-4dz6A:
undetectable		 3pcqB-4dz6A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 9 SER A  89
ARG A  94
ILE A 133
ALA A 135
ALA A 142
 None
ADP  A1001 ( 2.9A)
None
VN4  A1002 (-4.6A)
None
 1.29A 4fe1B-4dz6A:
undetectable		 4fe1B-4dz6A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 9 SER A  89
ILE A 133
ALA A 135
LEU A   9
ALA A 142
 None
None
VN4  A1002 (-4.6A)
None
None
 1.36A 4fe1B-4dz6A:
undetectable		 4fe1B-4dz6A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 10 SER A  89
ARG A  94
ILE A 133
ALA A 135
ALA A 142
 None
ADP  A1001 ( 2.9A)
None
VN4  A1002 (-4.6A)
None
 1.23A 4xk8B-4dz6A:
undetectable		 4xk8B-4dz6A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 10 SER A  89
ILE A 133
ALA A 135
LEU A   9
ALA A 142
 None
None
VN4  A1002 (-4.6A)
None
None
 1.33A 4xk8B-4dz6A:
undetectable		 4xk8B-4dz6A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 12 SER A  89
ARG A  94
ILE A 133
ALA A 135
ALA A 142
 None
ADP  A1001 ( 2.9A)
None
VN4  A1002 (-4.6A)
None
 1.28A 5oy02-4dz6A:
undetectable		 5oy02-4dz6A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 10 SER A  89
ARG A  94
ILE A 133
ALA A 135
ALA A 142
 None
ADP  A1001 ( 2.9A)
None
VN4  A1002 (-4.6A)
None
 1.25A 5oy0b-4dz6A:
undetectable		 5oy0b-4dz6A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4dz6 NUCLEOSIDE
DIPHOSPHATE KINASE
(Borreliella
burgdorferi) 		5 / 9 SER A  89
ARG A  94
ILE A 133
ALA A 135
ALA A 142
 None
ADP  A1001 ( 2.9A)
None
VN4  A1002 (-4.6A)
None
 1.34A 6hqbB-4dz6A:
undetectable		 6hqbB-4dz6A:
18.50