SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'VFV'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7A_A_PFLA4002_1 (SERUM ALBUMIN)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	3 / 3	PHE A 250 LEU A 134 SER A 235	None VFV A 580 (-4.4A) None	0.81A	1e7aA-4uhiA: undetectable	1e7aA-4uhiA: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G50_B_ESTB1600_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	LEU A 305 LEU A 286 ARG A 272 GLY A 162 LEU A 159	None None None None VFV A 580 (-4.5A)	1.05A	1g50B-4uhiA: 2.8	1g50B-4uhiA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G50_B_ESTB1600_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.24A	1g50B-4uhiA: 2.8	1g50B-4uhiA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G50_C_ESTC2600_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 11	LEU A 305 LEU A 286 ARG A 272 GLY A 162 LEU A 159	None None None None VFV A 580 (-4.5A)	1.05A	1g50C-4uhiA: 2.4	1g50C-4uhiA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G50_C_ESTC2600_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 11	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.24A	1g50C-4uhiA: 2.4	1g50C-4uhiA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GWR_A_ESTA600_1 (OESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 10	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.27A	1gwrA-4uhiA: undetectable	1gwrA-4uhiA: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PCG_A_ESTA1_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 10	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.16A	1pcgA-4uhiA: undetectable	1pcgA-4uhiA: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PCG_B_ESTB2_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 10	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.16A	1pcgB-4uhiA: 2.9	1pcgB-4uhiA: 21.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2WX2_A_TPFA1460_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	4 / 7	PHE A 139 TYR A 145 ALA A 311 THR A 315	VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A)	0.55A	2wx2A-4uhiA: 43.5	2wx2A-4uhiA: 35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2WX2_B_TPFB1460_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 8	TYR A 131 PHE A 139 TYR A 145 ALA A 311 THR A 315	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A)	0.48A	2wx2B-4uhiA: 34.3	2wx2B-4uhiA: 35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2X2N_A_X2NA1480_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	6 / 12	TYR A 131 PHE A 139 TYR A 145 ALA A 311 THR A 315 MET A 381	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) VFV A 600 (-3.8A)	1.12A	2x2nA-4uhiA: 38.2	2x2nA-4uhiA: 35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2X2N_C_X2NC1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	PHE A 139 TYR A 145 ALA A 311 THR A 315 MET A 381	VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) VFV A 600 (-3.8A)	1.08A	2x2nC-4uhiA: 38.6	2x2nC-4uhiA: 35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2X2N_D_X2ND1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	ILE A 75 TYR A 131 TYR A 145 THR A 315 MET A 381	None VFV A 580 (-4.1A) HEM A 540 (-4.5A) HEM A 540 (-3.6A) VFV A 600 (-3.8A)	0.73A	2x2nD-4uhiA: 38.6	2x2nD-4uhiA: 35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2X2N_D_X2ND1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	TYR A 131 TYR A 145 ALA A 311 THR A 315 MET A 381	VFV A 580 (-4.1A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) VFV A 600 (-3.8A)	0.73A	2x2nD-4uhiA: 38.6	2x2nD-4uhiA: 35.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ERD_A_DESA600_1 (ESTROGEN RECEPTOR ALPHA)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.22A	3erdA-4uhiA: undetectable	3erdA-4uhiA: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HM1_B_J3ZB1_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 11	LEU A 305 LEU A 286 ARG A 272 GLY A 162 LEU A 159	None None None None VFV A 580 (-4.5A)	1.05A	3hm1B-4uhiA: 2.5	3hm1B-4uhiA: 21.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JUS_A_ECLA600_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 8	TYR A 131 LEU A 134 THR A 135 TYR A 145 GLY A 307	VFV A 580 (-4.1A) VFV A 580 (-4.4A) VFV A 580 (-4.7A) HEM A 540 (-4.5A) VFV A 580 (-2.9A)	0.63A	3jusA-4uhiA: 61.6	3jusA-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JUS_A_ECLA600_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	7 / 8	TYR A 131 THR A 135 TYR A 145 GLY A 307 ALA A 311 THR A 315 ILE A 377	VFV A 580 (-4.1A) VFV A 580 (-4.7A) HEM A 540 (-4.5A) VFV A 580 (-2.9A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) HEM A 540 ( 3.9A)	0.49A	3jusA-4uhiA: 61.6	3jusA-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JUS_A_ECNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 8	TYR A 131 LEU A 134 THR A 135 TYR A 145 GLY A 307	VFV A 580 (-4.1A) VFV A 580 (-4.4A) VFV A 580 (-4.7A) HEM A 540 (-4.5A) VFV A 580 (-2.9A)	0.63A	3jusA-4uhiA: 61.6	3jusA-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JUS_A_ECNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	7 / 8	TYR A 131 THR A 135 TYR A 145 GLY A 307 ALA A 311 THR A 315 ILE A 377	VFV A 580 (-4.1A) VFV A 580 (-4.7A) HEM A 540 (-4.5A) VFV A 580 (-2.9A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) HEM A 540 ( 3.9A)	0.49A	3jusA-4uhiA: 61.6	3jusA-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JUS_B_ECNB602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	9 / 9	TYR A 131 LEU A 134 THR A 135 TYR A 145 PHE A 152 GLY A 307 ALA A 311 THR A 315 ILE A 377	VFV A 580 (-4.1A) VFV A 580 (-4.4A) VFV A 580 (-4.7A) HEM A 540 (-4.5A) HEM A 540 ( 4.3A) VFV A 580 (-2.9A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) HEM A 540 ( 3.9A)	0.64A	3jusB-4uhiA: 61.2	3jusB-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3KHM_A_TPFA501_1 (STEROL 14 ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 8	TYR A 131 PHE A 139 TYR A 145 ALA A 311 THR A 315	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A)	0.64A	3khmA-4uhiA: 37.9	3khmA-4uhiA: 35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3L4D_A_TPFA490_1 (STEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	4 / 8	PHE A 139 TYR A 145 ALA A 311 THR A 315	VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A)	0.86A	3l4dA-4uhiA: 37.5	3l4dA-4uhiA: 35.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3L4D_C_TPFC490_1 (STEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 9	TYR A 131 PHE A 139 TYR A 145 ALA A 311 THR A 315	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A)	0.89A	3l4dC-4uhiA: 45.2	3l4dC-4uhiA: 35.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3L4D_D_TPFD490_1 (STEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	4 / 8	PHE A 139 TYR A 145 ALA A 311 THR A 315	VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A)	0.69A	3l4dD-4uhiA: 38.2	3l4dD-4uhiA: 35.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LD6_A_KKKA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	6 / 12	PHE A 139 GLY A 307 ALA A 311 THR A 315 ILE A 379 MET A 487	VFV A 580 (-4.2A) VFV A 580 (-2.9A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) VFV A 600 (-4.7A) VFV A 580 (-3.6A)	0.97A	3ld6A-4uhiA: 61.6	3ld6A-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LD6_A_KKKA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	PHE A 139 TRP A 239 THR A 315 ILE A 379 MET A 487	VFV A 580 (-4.2A) VFV A 580 ( 3.5A) HEM A 540 (-3.6A) VFV A 600 (-4.7A) VFV A 580 (-3.6A)	1.30A	3ld6A-4uhiA: 61.6	3ld6A-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LD6_A_KKKA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	6 / 12	TYR A 131 PHE A 139 PHE A 234 TRP A 239 THR A 315 ILE A 379	VFV A 580 (-4.1A) VFV A 580 (-4.2A) VFV A 580 (-3.5A) VFV A 580 ( 3.5A) HEM A 540 (-3.6A) VFV A 600 (-4.7A)	1.17A	3ld6A-4uhiA: 61.6	3ld6A-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LD6_A_KKKA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	10 / 12	TYR A 131 PHE A 139 TYR A 145 PHE A 234 GLY A 307 ALA A 311 THR A 315 ILE A 377 ILE A 379 MET A 381	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) VFV A 580 (-3.5A) VFV A 580 (-2.9A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) HEM A 540 ( 3.9A) VFV A 600 (-4.7A) VFV A 600 (-3.8A)	0.77A	3ld6A-4uhiA: 61.6	3ld6A-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LD6_B_KKKB602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	PHE A 105 PHE A 139 PHE A 234 TRP A 239 THR A 315	VFV A 600 (-3.4A) VFV A 580 (-4.2A) VFV A 580 (-3.5A) VFV A 580 ( 3.5A) HEM A 540 (-3.6A)	1.33A	3ld6B-4uhiA: 45.8	3ld6B-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LD6_B_KKKB602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	PHE A 105 PHE A 139 TRP A 239 THR A 315 MET A 487	VFV A 600 (-3.4A) VFV A 580 (-4.2A) VFV A 580 ( 3.5A) HEM A 540 (-3.6A) VFV A 580 (-3.6A)	1.27A	3ld6B-4uhiA: 45.8	3ld6B-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LD6_B_KKKB602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	8 / 12	PHE A 105 TYR A 131 PHE A 139 GLY A 307 ALA A 311 THR A 315 ILE A 377 MET A 487	VFV A 600 (-3.4A) VFV A 580 (-4.1A) VFV A 580 (-4.2A) VFV A 580 (-2.9A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) HEM A 540 ( 3.9A) VFV A 580 (-3.6A)	0.78A	3ld6B-4uhiA: 45.8	3ld6B-4uhiA: 99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LD6_B_KKKB602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	10 / 12	PHE A 105 TYR A 131 PHE A 139 TYR A 145 PHE A 234 GLY A 307 ALA A 311 THR A 315 ILE A 377 MET A 381	VFV A 600 (-3.4A) VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) VFV A 580 (-3.5A) VFV A 580 (-2.9A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) HEM A 540 ( 3.9A) VFV A 600 (-3.8A)	0.75A	3ld6B-4uhiA: 45.8	3ld6B-4uhiA: 99.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OLS_B_ESTB600_1 (ESTROGEN RECEPTOR BETA)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.29A	3olsB-4uhiA: undetectable	3olsB-4uhiA: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q95_A_ESLA700_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	LEU A 305 LEU A 286 ARG A 272 GLY A 162 LEU A 159	None None None None VFV A 580 (-4.5A)	1.03A	3q95A-4uhiA: undetectable	3q95A-4uhiA: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UUD_A_ESTA600_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 11	LEU A 305 LEU A 286 ARG A 272 GLY A 162 LEU A 159	None None None None VFV A 580 (-4.5A)	1.07A	3uudA-4uhiA: undetectable	3uudA-4uhiA: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UUD_A_ESTA600_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 11	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.28A	3uudA-4uhiA: undetectable	3uudA-4uhiA: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PXM_A_ESTA2000_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	LEU A 305 LEU A 286 ARG A 272 GLY A 162 LEU A 159	None None None None VFV A 580 (-4.5A)	1.06A	4pxmA-4uhiA: 2.3	4pxmA-4uhiA: 21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UYM_A_VORA590_1 (14-ALPHA STEROL DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	4 / 7	TYR A 131 PHE A 139 ALA A 311 ILE A 377	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 ( 3.4A) HEM A 540 ( 3.9A)	0.81A	4uymA-4uhiA: 47.7	4uymA-4uhiA: 40.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UYM_B_VORB590_1 (14-ALPHA STEROL DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 7	TYR A 131 PHE A 139 TYR A 145 ALA A 311 ILE A 377	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 ( 3.9A)	0.83A	4uymB-4uhiA: 47.8	4uymB-4uhiA: 40.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXE_B_ESTB1000_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 10	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.27A	5dxeB-4uhiA: 2.4	5dxeB-4uhiA: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXG_A_ESTA1000_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 9	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.25A	5dxgA-4uhiA: 2.4	5dxgA-4uhiA: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HYR_A_ESTA601_1 (ESTROGEN RECEPTOR)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 10	LEU A 305 LEU A 296 LEU A 286 ARG A 272 LEU A 159	None None None None VFV A 580 (-4.5A)	1.25A	5hyrA-4uhiA: 2.4	5hyrA-4uhiA: 21.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JLC_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	ALA A 74 TYR A 131 PHE A 139 TYR A 145 PHE A 234	VFV A 600 ( 4.9A) VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) VFV A 580 (-3.5A)	1.00A	5jlcA-4uhiA: 44.2	5jlcA-4uhiA: 38.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5JLC_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	ALA A 74 TYR A 131 PHE A 139 TYR A 145 THR A 315	VFV A 600 ( 4.9A) VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 (-3.6A)	0.74A	5jlcA-4uhiA: 44.2	5jlcA-4uhiA: 38.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA305_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	3 / 3	THR A 485 MET A 487 HIS A 489	None VFV A 580 (-3.6A) None	0.81A	5uunA-4uhiA: undetectable	5uunA-4uhiA: 21.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6AY4_A_TPFA506_1 (CYP51, STEROL 14ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	6 / 10	TYR A 131 PHE A 139 TYR A 145 ALA A 311 THR A 315 CYH A 449	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) HEM A 540 (-2.3A)	0.67A	6ay4A-4uhiA: 48.1	6ay4A-4uhiA: 39.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6AY6_A_VORA501_1 (CYP51, STEROL 14ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	6 / 9	TYR A 131 PHE A 139 TYR A 145 ALA A 311 THR A 315 CYH A 449	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A) HEM A 540 (-2.3A)	0.71A	6ay6A-4uhiA: 48.2	6ay6A-4uhiA: 39.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6AYB_A_KKKA508_1 (CYP51, STEROL 14ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	TYR A 131 PHE A 139 TYR A 145 ALA A 311 MET A 381	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) VFV A 600 (-3.8A)	0.79A	6aybA-4uhiA: 48.4	6aybA-4uhiA: 39.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6AYB_A_KKKA508_1 (CYP51, STEROL 14ALPHA-DEMETHYLASE)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	TYR A 131 PHE A 139 TYR A 145 ALA A 311 THR A 315	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A)	0.60A	6aybA-4uhiA: 48.4	6aybA-4uhiA: 39.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AYC_A_1YNA502_1 (PROTEIN CYP51)	4uhi	STEROL 14-ALPHA DEMETHYLASE (Homo sapiens)	5 / 12	TYR A 131 PHE A 139 TYR A 145 ALA A 311 THR A 315	VFV A 580 (-4.1A) VFV A 580 (-4.2A) HEM A 540 (-4.5A) HEM A 540 ( 3.4A) HEM A 540 (-3.6A)	0.72A	6aycA-4uhiA: 48.4	6aycA-4uhiA: 13.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7A_A_PFLA4002_1","SERUM ALBUMIN","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",3,"PHE A 250;LEU A 134;SER A 235","None;VFV A 580 (-4.4A);None","0.81A","1e7aA-4uhiA:undetectable",null],["1G50_B_ESTB1600_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 286;ARG A 272;GLY A 162;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.05A","1g50B-4uhiA:2.8","1e7aA-4uhiA:21.22"],["1G50_B_ESTB1600_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.24A","1g50B-4uhiA:2.8","1g50B-4uhiA:18.57"],["1G50_C_ESTC2600_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 286;ARG A 272;GLY A 162;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.05A","1g50C-4uhiA:2.4","1g50B-4uhiA:18.57"],["1G50_C_ESTC2600_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.24A","1g50C-4uhiA:2.4","1g50C-4uhiA:18.57"],["1GWR_A_ESTA600_1","OESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.27A","1gwrA-4uhiA:undetectable","1g50C-4uhiA:18.57"],["1PCG_A_ESTA1_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.16A","1pcgA-4uhiA:undetectable","1gwrA-4uhiA:18.59"],["1PCG_B_ESTB2_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.16A","1pcgB-4uhiA:2.9","1pcgA-4uhiA:21.02"],["2WX2_A_TPFA1460_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",4,"PHE A 139;TYR A 145;ALA A 311;THR A 315","VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A)","0.55A","2wx2A-4uhiA:43.5","1pcgB-4uhiA:21.02"],["2WX2_B_TPFB1460_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;THR A 315","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A)","0.48A","2wx2B-4uhiA:34.3","2wx2A-4uhiA:35.79"],["2X2N_A_X2NA1480_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",6,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;THR A 315;MET A 381","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);VFV A 600 (-3.8A)","1.12A","2x2nA-4uhiA:38.2","2wx2B-4uhiA:35.79"],["2X2N_C_X2NC1479_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"PHE A 139;TYR A 145;ALA A 311;THR A 315;MET A 381","VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);VFV A 600 (-3.8A)","1.08A","2x2nC-4uhiA:38.6","2x2nA-4uhiA:35.27"],["2X2N_D_X2ND1479_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"ILE A  75;TYR A 131;TYR A 145;THR A 315;MET A 381","None;VFV A 580 (-4.1A);HEM A 540 (-4.5A);HEM A 540 (-3.6A);VFV A 600 (-3.8A)","0.73A","2x2nD-4uhiA:38.6","2x2nC-4uhiA:35.27"],["2X2N_D_X2ND1479_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;TYR A 145;ALA A 311;THR A 315;MET A 381","VFV A 580 (-4.1A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);VFV A 600 (-3.8A)","0.73A","2x2nD-4uhiA:38.6","2x2nD-4uhiA:35.27"],["3ERD_A_DESA600_1","ESTROGEN RECEPTOR ALPHA","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.22A","3erdA-4uhiA:undetectable","2x2nD-4uhiA:35.27"],["3HM1_B_J3ZB1_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 286;ARG A 272;GLY A 162;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.05A","3hm1B-4uhiA:2.5","3erdA-4uhiA:21.11"],["3JUS_A_ECLA600_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;LEU A 134;THR A 135;TYR A 145;GLY A 307","VFV A 580 (-4.1A);VFV A 580 (-4.4A);VFV A 580 (-4.7A);HEM A 540 (-4.5A);VFV A 580 (-2.9A)","0.63A","3jusA-4uhiA:61.6","3hm1B-4uhiA:21.28"],["3JUS_A_ECLA600_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",7,"TYR A 131;THR A 135;TYR A 145;GLY A 307;ALA A 311;THR A 315;ILE A 377","VFV A 580 (-4.1A);VFV A 580 (-4.7A);HEM A 540 (-4.5A);VFV A 580 (-2.9A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);HEM A 540 ( 3.9A)","0.49A","3jusA-4uhiA:61.6","3jusA-4uhiA:99.77"],["3JUS_A_ECNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;LEU A 134;THR A 135;TYR A 145;GLY A 307","VFV A 580 (-4.1A);VFV A 580 (-4.4A);VFV A 580 (-4.7A);HEM A 540 (-4.5A);VFV A 580 (-2.9A)","0.63A","3jusA-4uhiA:61.6","3jusA-4uhiA:99.77"],["3JUS_A_ECNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",7,"TYR A 131;THR A 135;TYR A 145;GLY A 307;ALA A 311;THR A 315;ILE A 377","VFV A 580 (-4.1A);VFV A 580 (-4.7A);HEM A 540 (-4.5A);VFV A 580 (-2.9A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);HEM A 540 ( 3.9A)","0.49A","3jusA-4uhiA:61.6","3jusA-4uhiA:99.77"],["3JUS_B_ECNB602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",9,"TYR A 131;LEU A 134;THR A 135;TYR A 145;PHE A 152;GLY A 307;ALA A 311;THR A 315;ILE A 377","VFV A 580 (-4.1A);VFV A 580 (-4.4A);VFV A 580 (-4.7A);HEM A 540 (-4.5A);HEM A 540 ( 4.3A);VFV A 580 (-2.9A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);HEM A 540 ( 3.9A)","0.64A","3jusB-4uhiA:61.2","3jusA-4uhiA:99.77"],["3KHM_A_TPFA501_1","STEROL 14 ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;THR A 315","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A)","0.64A","3khmA-4uhiA:37.9","3jusB-4uhiA:99.77"],["3L4D_A_TPFA490_1","STEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",4,"PHE A 139;TYR A 145;ALA A 311;THR A 315","VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A)","0.86A","3l4dA-4uhiA:37.5","3khmA-4uhiA:35.79"],["3L4D_C_TPFC490_1","STEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;THR A 315","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A)","0.89A","3l4dC-4uhiA:45.2","3l4dA-4uhiA:35.73"],["3L4D_D_TPFD490_1","STEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",4,"PHE A 139;TYR A 145;ALA A 311;THR A 315","VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A)","0.69A","3l4dD-4uhiA:38.2","3l4dC-4uhiA:35.73"],["3LD6_A_KKKA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",6,"PHE A 139;GLY A 307;ALA A 311;THR A 315;ILE A 379;MET A 487","VFV A 580 (-4.2A);VFV A 580 (-2.9A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);VFV A 600 (-4.7A);VFV A 580 (-3.6A)","0.97A","3ld6A-4uhiA:61.6","3l4dD-4uhiA:35.73"],["3LD6_A_KKKA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"PHE A 139;TRP A 239;THR A 315;ILE A 379;MET A 487","VFV A 580 (-4.2A);VFV A 580 ( 3.5A);HEM A 540 (-3.6A);VFV A 600 (-4.7A);VFV A 580 (-3.6A)","1.30A","3ld6A-4uhiA:61.6","3ld6A-4uhiA:99.77"],["3LD6_A_KKKA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",6,"TYR A 131;PHE A 139;PHE A 234;TRP A 239;THR A 315;ILE A 379","VFV A 580 (-4.1A);VFV A 580 (-4.2A);VFV A 580 (-3.5A);VFV A 580 ( 3.5A);HEM A 540 (-3.6A);VFV A 600 (-4.7A)","1.17A","3ld6A-4uhiA:61.6","3ld6A-4uhiA:99.77"],["3LD6_A_KKKA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",10,"TYR A 131;PHE A 139;TYR A 145;PHE A 234;GLY A 307;ALA A 311;THR A 315;ILE A 377;ILE A 379;MET A 381","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);VFV A 580 (-3.5A);VFV A 580 (-2.9A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);HEM A 540 ( 3.9A);VFV A 600 (-4.7A);VFV A 600 (-3.8A)","0.77A","3ld6A-4uhiA:61.6","3ld6A-4uhiA:99.77"],["3LD6_B_KKKB602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"PHE A 105;PHE A 139;PHE A 234;TRP A 239;THR A 315","VFV A 600 (-3.4A);VFV A 580 (-4.2A);VFV A 580 (-3.5A);VFV A 580 ( 3.5A);HEM A 540 (-3.6A)","1.33A","3ld6B-4uhiA:45.8","3ld6A-4uhiA:99.77"],["3LD6_B_KKKB602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"PHE A 105;PHE A 139;TRP A 239;THR A 315;MET A 487","VFV A 600 (-3.4A);VFV A 580 (-4.2A);VFV A 580 ( 3.5A);HEM A 540 (-3.6A);VFV A 580 (-3.6A)","1.27A","3ld6B-4uhiA:45.8","3ld6B-4uhiA:99.77"],["3LD6_B_KKKB602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",8,"PHE A 105;TYR A 131;PHE A 139;GLY A 307;ALA A 311;THR A 315;ILE A 377;MET A 487","VFV A 600 (-3.4A);VFV A 580 (-4.1A);VFV A 580 (-4.2A);VFV A 580 (-2.9A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);HEM A 540 ( 3.9A);VFV A 580 (-3.6A)","0.78A","3ld6B-4uhiA:45.8","3ld6B-4uhiA:99.77"],["3LD6_B_KKKB602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",10,"PHE A 105;TYR A 131;PHE A 139;TYR A 145;PHE A 234;GLY A 307;ALA A 311;THR A 315;ILE A 377;MET A 381","VFV A 600 (-3.4A);VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);VFV A 580 (-3.5A);VFV A 580 (-2.9A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);HEM A 540 ( 3.9A);VFV A 600 (-3.8A)","0.75A","3ld6B-4uhiA:45.8","3ld6B-4uhiA:99.77"],["3OLS_B_ESTB600_1","ESTROGEN RECEPTOR BETA","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.29A","3olsB-4uhiA:undetectable","3ld6B-4uhiA:99.77"],["3Q95_A_ESLA700_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 286;ARG A 272;GLY A 162;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.03A","3q95A-4uhiA:undetectable","3olsB-4uhiA:20.41"],["3UUD_A_ESTA600_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 286;ARG A 272;GLY A 162;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.07A","3uudA-4uhiA:undetectable","3q95A-4uhiA:21.57"],["3UUD_A_ESTA600_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.28A","3uudA-4uhiA:undetectable","3uudA-4uhiA:21.70"],["4PXM_A_ESTA2000_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 286;ARG A 272;GLY A 162;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.06A","4pxmA-4uhiA:2.3","3uudA-4uhiA:21.70"],["4UYM_A_VORA590_1","14-ALPHA STEROL DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",4,"TYR A 131;PHE A 139;ALA A 311;ILE A 377","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 ( 3.4A);HEM A 540 ( 3.9A)","0.81A","4uymA-4uhiA:47.7","4pxmA-4uhiA:21.24"],["4UYM_B_VORB590_1","14-ALPHA STEROL DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;ILE A 377","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 ( 3.9A)","0.83A","4uymB-4uhiA:47.8","4uymA-4uhiA:40.43"],["5DXE_B_ESTB1000_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.27A","5dxeB-4uhiA:2.4","4uymB-4uhiA:40.43"],["5DXG_A_ESTA1000_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.25A","5dxgA-4uhiA:2.4","5dxeB-4uhiA:21.11"],["5HYR_A_ESTA601_1","ESTROGEN RECEPTOR","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"LEU A 305;LEU A 296;LEU A 286;ARG A 272;LEU A 159","None;None;None;None;VFV A 580 (-4.5A)","1.25A","5hyrA-4uhiA:2.4","5dxgA-4uhiA:21.11"],["5JLC_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"ALA A  74;TYR A 131;PHE A 139;TYR A 145;PHE A 234","VFV A 600 ( 4.9A);VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);VFV A 580 (-3.5A)","1.00A","5jlcA-4uhiA:44.2","5hyrA-4uhiA:21.76"],["5JLC_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"ALA A  74;TYR A 131;PHE A 139;TYR A 145;THR A 315","VFV A 600 ( 4.9A);VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 (-3.6A)","0.74A","5jlcA-4uhiA:44.2","5jlcA-4uhiA:38.64"],["5UUN_A_ACTA305_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",3,"THR A 485;MET A 487;HIS A 489","None;VFV A 580 (-3.6A);None","0.81A","5uunA-4uhiA:undetectable","5jlcA-4uhiA:38.64"],["6AY4_A_TPFA506_1","CYP51, STEROL 14ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",6,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;THR A 315;CYH A 449","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);HEM A 540 (-2.3A)","0.67A","6ay4A-4uhiA:48.1","5uunA-4uhiA:21.52"],["6AY6_A_VORA501_1","CYP51, STEROL 14ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",6,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;THR A 315;CYH A 449","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A);HEM A 540 (-2.3A)","0.71A","6ay6A-4uhiA:48.2","6ay4A-4uhiA:39.74"],["6AYB_A_KKKA508_1","CYP51, STEROL 14ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;MET A 381","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);VFV A 600 (-3.8A)","0.79A","6aybA-4uhiA:48.4","6ay6A-4uhiA:39.74"],["6AYB_A_KKKA508_1","CYP51, STEROL 14ALPHA-DEMETHYLASE","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;THR A 315","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A)","0.60A","6aybA-4uhiA:48.4","6aybA-4uhiA:39.74"],["6AYC_A_1YNA502_1","PROTEIN CYP51","4uhi","STEROL 14-ALPHA DEMETHYLASE","Homo sapiens",5,"TYR A 131;PHE A 139;TYR A 145;ALA A 311;THR A 315","VFV A 580 (-4.1A);VFV A 580 (-4.2A);HEM A 540 (-4.5A);HEM A 540 ( 3.4A);HEM A 540 (-3.6A)","0.72A","6aycA-4uhiA:48.4","6aybA-4uhiA:39.74"]]