SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'VC5'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 6aom ENDOPLASMIN
(Canis
lupus) 		5 / 12 LEU A 104
LEU A 159
ILE A 247
PHE A 199
PHE A  78
 VC5  A 409 (-4.5A)
None
VC5  A 409 (-4.4A)
VC5  A 409 (-4.2A)
None
 0.94A 2ygqA-6aomA:
undetectable		 2ygqA-6aomA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 6aom ENDOPLASMIN
(Canis
lupus) 		4 / 7 GLY A 151
ALA A 108
ASP A 113
ASN A 129
 None
VC5  A 409 ( 4.7A)
None
None
 0.92A 5mvsA-6aomA:
undetectable		 5mvsA-6aomA:
22.45