SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'URI'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
THR A  93
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.28A 1jdvA-5lhvA:
16.0
1jdvD-5lhvA:
31.3		 1jdvA-5lhvA:
31.27
1jdvD-5lhvA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
THR A  93
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.28A 1jdvB-5lhvA:
31.4
1jdvC-5lhvA:
32.0		 1jdvB-5lhvA:
31.27
1jdvC-5lhvA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
THR A  93
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.27A 1jdvA-5lhvA:
16.0
1jdvD-5lhvA:
31.3		 1jdvA-5lhvA:
31.27
1jdvD-5lhvA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 12 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.28A 1jdvE-5lhvA:
31.4
1jdvF-5lhvA:
31.9		 1jdvE-5lhvA:
31.27
1jdvF-5lhvA:
31.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1i5l PUTATIVE SNRNP
SM-LIKE PROTEIN
AF-SM1
(Archaeoglobus
fulgidus) 		5 / 9 LEU A   9
VAL A  67
GLY A  64
LEU A   6
TYR A  34
 None
None
URI  A 201 (-3.6A)
None
None
 1.42A 1lwfA-1i5lA:
undetectable		 1lwfA-1i5lA:
10.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.34A 1odiA-5lhvA:
24.5		 1odiA-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiA-5lhvA:
24.5		 1odiA-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.24A 1odiB-5lhvA:
33.5		 1odiB-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiB-5lhvA:
33.5		 1odiB-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.23A 1odiC-5lhvA:
33.5		 1odiC-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiC-5lhvA:
33.5		 1odiC-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.32A 1odiD-5lhvA:
33.4		 1odiD-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A 217
GLU A 195
GLU A 197
SER A 240
 SO4  A 301 ( 3.0A)
None
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.31A 1odiD-5lhvA:
33.4		 1odiD-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiD-5lhvA:
33.4		 1odiD-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.32A 1odiE-5lhvA:
33.6		 1odiE-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A 217
GLU A 195
GLU A 197
SER A 240
 SO4  A 301 ( 3.0A)
None
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.26A 1odiE-5lhvA:
33.6		 1odiE-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiE-5lhvA:
33.6		 1odiE-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A 217
GLU A 195
GLU A 197
SER A 240
 SO4  A 301 ( 3.0A)
None
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.30A 1odiF-5lhvA:
33.2		 1odiF-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.28A 1odiF-5lhvA:
33.2		 1odiF-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 1odiF-5lhvA:
33.2		 1odiF-5lhvA:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 9 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.26A 1pk7A-5lhvA:
31.9		 1pk7A-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.26A 1pk7C-5lhvA:
31.6		 1pk7C-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.23A 1pk9A-5lhvA:
31.9		 1pk9A-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 9 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.23A 1pk9B-5lhvA:
31.9		 1pk9B-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.31A 1pk9C-5lhvA:
30.2		 1pk9C-5lhvA:
31.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.44A 1pw7A-5lhvA:
31.9		 1pw7A-5lhvA:
31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A 220
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
URA  A 304 (-4.3A)
 1.47A 1pw7A-5lhvA:
31.9		 1pw7A-5lhvA:
31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 9 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.34A 1pw7B-5lhvA:
31.7		 1pw7B-5lhvA:
31.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.23A 1rxcB-5lhvA:
24.3		 1rxcB-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.29A 1rxcC-5lhvA:
42.9		 1rxcC-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.26A 1rxcD-5lhvA:
43.7		 1rxcD-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.17A 1rxcE-5lhvA:
43.7		 1rxcE-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.22A 1rxcF-5lhvA:
43.8		 1rxcF-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.26A 1rxcI-5lhvA:
44.0		 1rxcI-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.22A 1rxcK-5lhvA:
42.1		 1rxcK-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.19A 1rxcL-5lhvA:
43.8		 1rxcL-5lhvA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.37A 1vhwA-5lhvA:
32.3
1vhwD-5lhvA:
32.4		 1vhwA-5lhvA:
26.81
1vhwD-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.42A 1vhwC-5lhvA:
32.4
1vhwE-5lhvA:
32.2		 1vhwC-5lhvA:
26.81
1vhwE-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A 220
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
URA  A 304 (-4.3A)
 1.46A 1vhwC-5lhvA:
32.4
1vhwE-5lhvA:
32.2		 1vhwC-5lhvA:
26.81
1vhwE-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.40A 1vhwA-5lhvA:
32.3
1vhwD-5lhvA:
32.4		 1vhwA-5lhvA:
26.81
1vhwD-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A 220
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
URA  A 304 (-4.3A)
 1.47A 1vhwA-5lhvA:
32.3
1vhwD-5lhvA:
32.4		 1vhwA-5lhvA:
26.81
1vhwD-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
None
 1.37A 1vhwC-5lhvA:
32.4
1vhwE-5lhvA:
32.2		 1vhwC-5lhvA:
26.81
1vhwE-5lhvA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.35A 1vhwB-5lhvA:
32.2
1vhwF-5lhvA:
31.8		 1vhwB-5lhvA:
26.81
1vhwF-5lhvA:
26.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.45A 1z35A-5lhvA:
31.4		 1z35A-5lhvA:
30.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 9 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.37A 1z37A-5lhvA:
31.4		 1z37A-5lhvA:
30.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.30A 2ac7A-5lhvA:
30.2
2ac7B-5lhvA:
30.2		 2ac7A-5lhvA:
33.46
2ac7B-5lhvA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.30A 2ac7A-5lhvA:
30.2
2ac7B-5lhvA:
30.2		 2ac7A-5lhvA:
33.46
2ac7B-5lhvA:
33.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 5 PHE A  97
PHE A 270
PHE A 333
ILE A 277
 None
DMU  A 422 ( 4.1A)
URI  A 419 (-4.9A)
None
 1.37A 2v0mD-3tijA:
undetectable		 2v0mD-3tijA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		4 / 6 GLY A  25
ILE A  23
GLU A 197
ASP A  26
 SO4  A 301 (-3.3A)
None
URI  A 303 (-2.7A)
None
 0.97A 3a7eA-5lhvA:
undetectable		 3a7eA-5lhvA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 ALA A 367
ALA A 205
GLY A 186
THR A 155
VAL A 374
 None
None
6ZL  A 501 ( 4.4A)
URI  A 505 ( 4.5A)
URI  A 505 (-4.6A)
 1.05A 3c6gA-5l26A:
undetectable		 3c6gA-5l26A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 ALA A 367
ALA A 205
GLY A 186
THR A 155
VAL A 374
 None
None
6ZL  A 501 ( 4.4A)
URI  A 505 ( 4.5A)
URI  A 505 (-4.6A)
 1.09A 3c6gB-5l26A:
undetectable		 3c6gB-5l26A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 PHE A 161
GLN A 165
ARG A 167
GLU A 195
MET A 196
ILE A 220
 URI  A 303 (-4.3A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.18A 3kvrA-5lhvA:
26.1		 3kvrA-5lhvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		7 / 10 THR A  93
GLY A  95
PHE A 161
GLN A 165
ARG A 167
GLU A 195
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 (-4.3A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
 0.33A 3kvrA-5lhvA:
26.1		 3kvrA-5lhvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		7 / 10 THR A  93
GLY A  95
PHE A 161
GLN A 165
ARG A 167
GLU A 195
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 (-4.3A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
 0.30A 3kvrB-5lhvA:
26.0		 3kvrB-5lhvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 THR A  93
PHE A 161
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URI  A 303 (-4.3A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.35A 3kvrB-5lhvA:
26.0		 3kvrB-5lhvA:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 3kvvA-5lhvA:
44.2		 3kvvA-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.16A 3kvvB-5lhvA:
43.8		 3kvvB-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.17A 3kvvC-5lhvA:
43.3		 3kvvC-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.19A 3kvvD-5lhvA:
43.5		 3kvvD-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.11A 3kvvE-5lhvA:
44.5		 3kvvE-5lhvA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 3kvvF-5lhvA:
42.8		 3kvvF-5lhvA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 9 GLN A 165
ARG A 167
GLU A 195
MET A 196
ILE A 220
 URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.06A 3nbqA-5lhvA:
26.0		 3nbqA-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 9 THR A  93
GLY A  95
GLN A 165
ARG A 167
GLU A 195
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
 0.32A 3nbqA-5lhvA:
26.0		 3nbqA-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.33A 3nbqB-5lhvA:
26.0		 3nbqB-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.28A 3nbqC-5lhvA:
25.9		 3nbqC-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 9 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ARG A 222
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.50A 3nbqD-5lhvA:
26.1		 3nbqD-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.24A 3u40B-5lhvA:
30.2
3u40C-5lhvA:
13.2		 3u40B-5lhvA:
26.79
3u40C-5lhvA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.21A 3u40D-5lhvA:
30.4
3u40E-5lhvA:
29.7		 3u40D-5lhvA:
26.79
3u40E-5lhvA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.30A 3u40D-5lhvA:
30.4
3u40E-5lhvA:
29.7		 3u40D-5lhvA:
26.79
3u40E-5lhvA:
26.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 11 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 3uawA-5lhvA:
14.1		 3uawA-5lhvA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
GLU A 197
ILE A  97
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 (-2.7A)
None
 1.39A 3uayA-5lhvA:
13.0		 3uayA-5lhvA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
ILE A 220
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
URA  A 304 (-4.3A)
 1.50A 3uayA-5lhvA:
13.0		 3uayA-5lhvA:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 10 ARG A  90
THR A  93
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.32A 3uayA-5lhvA:
13.0		 3uayA-5lhvA:
33.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 4eg2 CYTIDINE DEAMINASE
(Vibrio
cholerae) 		5 / 11 ARG A   4
GLY A 252
ALA A 103
GLY A  74
GLU A 104
 None
None
URI  A 302 (-3.8A)
None
URI  A 302 (-3.0A)
 1.17A 4a6nA-4eg2A:
undetectable		 4a6nA-4eg2A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.26A 4d9hA-5lhvA:
30.7		 4d9hA-5lhvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 10 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.30A 4da7A-5lhvA:
30.5		 4da7A-5lhvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 11 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.28A 4danA-5lhvA:
30.1		 4danA-5lhvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 12 ARG A  90
GLY A  95
GLU A 195
MET A 196
GLU A 197
 SO4  A 301 ( 3.0A)
URI  A 303 ( 3.4A)
URI  A 303 ( 4.6A)
URI  A 303 ( 3.7A)
URI  A 303 (-2.7A)
 0.36A 4danA-5lhvA:
30.1
4danB-5lhvA:
30.2		 4danA-5lhvA:
28.88
4danB-5lhvA:
28.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.20A 4e1vA-5lhvA:
42.1		 4e1vA-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 4e1vB-5lhvA:
20.0		 4e1vB-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 4e1vC-5lhvA:
20.2		 4e1vC-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.17A 4e1vD-5lhvA:
42.2		 4e1vD-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.18A 4e1vE-5lhvA:
42.2		 4e1vE-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 6 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.23A 4e1vF-5lhvA:
41.8		 4e1vF-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.40A 4e1vG-5lhvA:
19.1		 4e1vG-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 8 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
 0.17A 4e1vH-5lhvA:
19.6		 4e1vH-5lhvA:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A 185
LEU A 105
ASN A 331
GLU A 332
PHE A 366
 URI  A 419 ( 3.8A)
None
URI  A 419 ( 4.0A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
 1.03A 4pb1A-3tijA:
72.1		 4pb1A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		12 / 12 GLY A 153
GLN A 154
GLU A 156
ALA A 185
TYR A 192
LEU A 259
ASN A 331
GLU A 332
PHE A 366
ASN A 368
SER A 371
ILE A 374
 NA  A 421 ( 3.9A)
URI  A 419 (-3.9A)
URI  A 419 ( 4.3A)
URI  A 419 ( 3.8A)
None
URI  A 419 ( 4.9A)
URI  A 419 ( 4.0A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
URI  A 419 (-3.7A)
URI  A 419 (-2.6A)
URI  A 419 (-4.0A)
 0.17A 4pb1A-3tijA:
72.1		 4pb1A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		9 / 12 GLY A 153
GLN A 154
ALA A 185
TYR A 192
ASN A 331
GLU A 332
PHE A 366
ASN A 368
SER A 371
 NA  A 506 (-3.8A)
URI  A 505 (-3.9A)
URI  A 505 ( 3.7A)
None
URI  A 505 ( 4.7A)
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
URI  A 505 (-3.2A)
URI  A 505 (-2.4A)
 0.41A 4pb1A-5l26A:
63.9		 4pb1A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		6 / 12 GLY A 153
GLU A 156
ALA A 185
TYR A 192
GLU A 332
PHE A 366
 NA  A 506 (-3.8A)
None
URI  A 505 ( 3.7A)
None
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
 0.83A 4pb1A-5l26A:
63.9		 4pb1A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A 185
LEU A 105
ASN A 331
GLU A 332
PHE A 366
 URI  A 419 ( 3.8A)
None
URI  A 419 ( 4.0A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
 1.05A 4pd5A-3tijA:
71.1		 4pd5A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 153
ALA A 185
VAL A 188
TYR A 192
ASN A 405
 NA  A 421 ( 3.9A)
URI  A 419 ( 3.8A)
None
None
None
 1.21A 4pd5A-3tijA:
71.1		 4pd5A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		12 / 12 GLY A 153
GLN A 154
ALA A 185
VAL A 188
TYR A 192
LEU A 259
ASN A 331
GLU A 332
PHE A 366
ASN A 368
SER A 371
ILE A 374
 NA  A 421 ( 3.9A)
URI  A 419 (-3.9A)
URI  A 419 ( 3.8A)
None
None
URI  A 419 ( 4.9A)
URI  A 419 ( 4.0A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
URI  A 419 (-3.7A)
URI  A 419 (-2.6A)
URI  A 419 (-4.0A)
 0.28A 4pd5A-3tijA:
71.1		 4pd5A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 GLY A 153
ALA A 185
VAL A 188
TYR A 192
ASN A 405
 NA  A 506 (-3.8A)
URI  A 505 ( 3.7A)
None
None
None
 1.13A 4pd5A-5l26A:
64.0		 4pd5A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		10 / 12 GLY A 153
GLN A 154
ALA A 185
VAL A 188
TYR A 192
ASN A 331
GLU A 332
PHE A 366
ASN A 368
SER A 371
 NA  A 506 (-3.8A)
URI  A 505 (-3.9A)
URI  A 505 ( 3.7A)
None
None
URI  A 505 ( 4.7A)
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
URI  A 505 (-3.2A)
URI  A 505 (-2.4A)
 0.42A 4pd5A-5l26A:
64.0		 4pd5A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 153
ALA A 185
VAL A 188
TYR A 192
ASN A 405
 NA  A 421 ( 3.9A)
URI  A 419 ( 3.8A)
None
None
None
 1.22A 4pd9A-3tijA:
71.3		 4pd9A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		12 / 12 GLY A 153
GLN A 154
GLU A 156
ALA A 185
VAL A 188
TYR A 192
LEU A 259
GLU A 332
PHE A 366
ASN A 368
SER A 371
ILE A 374
 NA  A 421 ( 3.9A)
URI  A 419 (-3.9A)
URI  A 419 ( 4.3A)
URI  A 419 ( 3.8A)
None
None
URI  A 419 ( 4.9A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
URI  A 419 (-3.7A)
URI  A 419 (-2.6A)
URI  A 419 (-4.0A)
 0.24A 4pd9A-3tijA:
71.3		 4pd9A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		5 / 12 GLY A 153
ALA A 185
VAL A 188
TYR A 192
ASN A 405
 NA  A 506 (-3.8A)
URI  A 505 ( 3.7A)
None
None
None
 1.14A 4pd9A-5l26A:
63.9		 4pd9A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		9 / 12 GLY A 153
GLN A 154
ALA A 185
VAL A 188
TYR A 192
GLU A 332
PHE A 366
ASN A 368
SER A 371
 NA  A 506 (-3.8A)
URI  A 505 (-3.9A)
URI  A 505 ( 3.7A)
None
None
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
URI  A 505 (-3.2A)
URI  A 505 (-2.4A)
 0.38A 4pd9A-5l26A:
63.9		 4pd9A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		7 / 12 GLY A 153
GLU A 156
ALA A 185
VAL A 188
TYR A 192
GLU A 332
PHE A 366
 NA  A 506 (-3.8A)
None
URI  A 505 ( 3.7A)
None
None
URI  A 505 (-3.2A)
URI  A 505 (-3.8A)
 0.78A 4pd9A-5l26A:
63.9		 4pd9A-5l26A:
67.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		3 / 3 THR A 155
ASN A 331
PHE A 333
 None
URI  A 419 ( 4.0A)
URI  A 419 (-4.9A)
 0.16A 4pd9A-3tijA:
71.3		 4pd9A-3tijA:
99.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.39A 4txnA-5lhvA:
25.0		 4txnA-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.36A 4txnA-5lhvA:
25.0		 4txnA-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.37A 4txnB-5lhvA:
25.0		 4txnB-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.39A 4txnB-5lhvA:
25.0		 4txnB-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.40A 4txnC-5lhvA:
25.0		 4txnC-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.36A 4txnC-5lhvA:
25.0		 4txnC-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLN A 165
ARG A 167
MET A 196
ILE A 220
 SO4  A 301 ( 2.9A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
URA  A 304 (-4.3A)
 1.38A 4txnD-5lhvA:
24.9		 4txnD-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		5 / 7 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.38A 4txnD-5lhvA:
24.9		 4txnD-5lhvA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 12 GLY A  69
GLU A 197
GLY A  67
GLY A  25
SER A  72
ALA A 118
 None
URI  A 303 (-2.7A)
NA  A 307 ( 4.0A)
SO4  A 301 (-3.3A)
NA  A 307 (-2.9A)
None
 1.32A 4uciA-5lhvA:
undetectable		 4uciA-5lhvA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 12 GLY A  69
GLU A 197
GLY A  67
GLY A  25
SER A  72
ALA A 118
 None
URI  A 303 (-2.7A)
NA  A 307 ( 4.0A)
SO4  A 301 (-3.3A)
NA  A 307 (-2.9A)
None
 1.32A 4uciB-5lhvA:
undetectable		 4uciB-5lhvA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5lhv URIDINE
PHOSPHORYLASE
(Vibrio
cholerae) 		6 / 12 GLY A  69
GLU A 197
GLY A  67
GLY A  25
SER A  72
ALA A 118
 None
URI  A 303 (-2.7A)
NA  A 307 ( 4.0A)
SO4  A 301 (-3.3A)
NA  A 307 (-2.9A)
None
 1.27A 4uckA-5lhvA:
undetectable		 4uckA-5lhvA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5l26 NUCLEOSIDE PERMEASE
(Neisseria
wadsworthii) 		3 / 3 SER A 187
SER A 109
PHE A 366
 URI  A 505 ( 4.3A)
None
URI  A 505 (-3.8A)
 0.88A 5mugA-5l26A:
undetectable		 5mugA-5l26A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4eg2 CYTIDINE DEAMINASE
(Vibrio
cholerae) 		3 / 3 CYH A 106
MET A  90
ASN A  89
 None
None
URI  A 302 (-4.0A)
 1.16A 5qh8A-4eg2A:
undetectable		 5qh8A-4eg2A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 4eg2 CYTIDINE DEAMINASE
(Vibrio
cholerae) 		3 / 3 ILE A 124
THR A 123
PRO A 128
 None
None
URI  A 302 (-4.7A)
 0.60A 6ncsA-4eg2A:
undetectable		 6ncsA-4eg2A:
22.36