SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'URC'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 10 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.93A 1c9sN-4yswA:
undetectable
1c9sO-4yswA:
undetectable		 1c9sN-4yswA:
5.06
1c9sO-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.91A 1c9sP-4yswA:
undetectable
1c9sQ-4yswA:
undetectable		 1c9sP-4yswA:
5.06
1c9sQ-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 10 GLY A 915
GLY A1006
HIS A 884
ALA A1079
ILE A1007
 BCT  A3006 (-3.9A)
None
None
URC  A3007 (-3.4A)
None
 0.91A 1c9sL-4yswA:
undetectable
1c9sV-4yswA:
undetectable		 1c9sL-4yswA:
5.06
1c9sV-4yswA:
5.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		8 / 9 GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.44A 1fo4A-4yswA:
45.7		 1fo4A-4yswA:
86.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		6 / 7 GLU A 802
SER A 876
ARG A 880
PHE A 914
THR A1010
ALA A1078
 URC  A3007 (-3.0A)
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
URC  A3007 (-3.5A)
 0.38A 1fo4B-4yswA:
45.6		 1fo4B-4yswA:
86.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.92A 1gtfQ-4yswA:
undetectable
1gtfR-4yswA:
undetectable		 1gtfQ-4yswA:
5.06
1gtfR-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.92A 1gtfS-4yswA:
undetectable
1gtfT-4yswA:
undetectable		 1gtfS-4yswA:
5.06
1gtfT-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.94A 1gtnT-4yswA:
undetectable
1gtnU-4yswA:
undetectable		 1gtnT-4yswA:
5.06
1gtnU-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 12 GLY A 915
GLY A1006
HIS A 884
ALA A1079
ILE A1007
 BCT  A3006 (-3.9A)
None
None
URC  A3007 (-3.4A)
None
 0.93A 1gtnL-4yswA:
undetectable
1gtnV-4yswA:
undetectable		 1gtnL-4yswA:
5.06
1gtnV-4yswA:
5.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		10 / 12 LEU A 648
ASN A 768
GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
ALA A1078
ALA A1079
 None
None
URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
 0.36A 1n5xA-4yswA:
44.9		 1n5xA-4yswA:
86.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		10 / 12 LEU A 648
LYS A 771
GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
ALA A1078
ALA A1079
 None
None
URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
 0.72A 1n5xA-4yswA:
44.9		 1n5xA-4yswA:
86.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		10 / 12 LEU A 648
ASN A 768
GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
ALA A1078
ALA A1079
 None
None
URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
 0.35A 1n5xB-4yswA:
44.9		 1n5xB-4yswA:
86.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		10 / 12 LEU A 648
LYS A 771
GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
ALA A1078
ALA A1079
 None
None
URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
 0.72A 1n5xB-4yswA:
44.9		 1n5xB-4yswA:
86.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 3rp7 FLAVOPROTEIN
MONOOXYGENASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 295
ARG A 204
MET A  71
LEU A  87
THR A  94
 URC  A7579 ( 3.5A)
URC  A7579 (-2.9A)
None
None
None
 1.48A 1p93C-3rp7A:
undetectable		 1p93C-3rp7A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 12 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.94A 1utdO-4yswA:
undetectable
1utdP-4yswA:
undetectable		 1utdO-4yswA:
5.06
1utdP-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.93A 1utdP-4yswA:
undetectable
1utdQ-4yswA:
undetectable		 1utdP-4yswA:
5.06
1utdQ-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.92A 1utdS-4yswA:
undetectable
1utdT-4yswA:
undetectable		 1utdS-4yswA:
5.06
1utdT-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 10 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.95A 1utdU-4yswA:
undetectable
1utdV-4yswA:
undetectable		 1utdU-4yswA:
5.06
1utdV-4yswA:
5.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		10 / 10 GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
PHE A1009
THR A1010
ALA A1078
ALA A1079
GLU A1261
 URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-4.6A)
URC  A3007 (-3.5A)
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
URC  A3007 (-2.9A)
 0.37A 1wygA-4yswA:
45.9		 1wygA-4yswA:
99.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 6 ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.17A 2e1qA-4yswA:
46.1		 2e1qA-4yswA:
90.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2E1Q_B_SALB3006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 4 ARG A 880
PHE A 914
THR A1010
ALA A1079
 URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
 0.15A 2e1qB-4yswA:
46.1		 2e1qB-4yswA:
90.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 6 ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.24A 2e1qC-4yswA:
45.9		 2e1qC-4yswA:
90.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 5 ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.21A 2e1qD-4yswA:
46.1		 2e1qD-4yswA:
90.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 8 LEU A1014
LEU A1011
ALA A1079
ALA A 910
 None
None
URC  A3007 (-3.4A)
URC  A3007 (-4.0A)
 0.73A 2vcvP-4yswA:
undetectable		 2vcvP-4yswA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 8 GLN A 918
PHE A 914
GLY A 915
GLY A 800
 BCT  A3006 (-3.0A)
URC  A3007 ( 3.4A)
BCT  A3006 (-3.9A)
None
 0.81A 2y6rB-4yswA:
undetectable		 2y6rB-4yswA:
14.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		8 / 9 GLU A 802
SER A 876
ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1078
ALA A1079
 URC  A3007 (-3.0A)
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
 0.32A 3ax7B-4yswA:
44.3		 3ax7B-4yswA:
86.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		8 / 8 GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
ALA A1078
ALA A1079
 URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
 0.32A 3ax9B-4yswA:
44.0		 3ax9B-4yswA:
86.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		6 / 6 GLU A 802
ARG A 880
PHE A 914
THR A1010
ALA A1078
ALA A1079
 URC  A3007 (-3.0A)
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
URC  A3007 (-3.5A)
URC  A3007 (-3.4A)
 0.35A 3ns1C-4yswA:
58.8		 3ns1C-4yswA:
59.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		8 / 9 GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.32A 3unaA-4yswA:
45.8		 3unaA-4yswA:
86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		8 / 9 GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.30A 3unaB-4yswA:
45.7		 3unaB-4yswA:
86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		8 / 9 GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.34A 3uncA-4yswA:
46.2		 3uncA-4yswA:
86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		8 / 9 GLU A 802
LEU A 873
SER A 876
ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.0A)
None
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.35A 3uncB-4yswA:
46.0		 3uncB-4yswA:
86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		6 / 7 GLU A 802
ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.0A)
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.36A 3uniA-4yswA:
45.4		 3uniA-4yswA:
86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		7 / 8 GLU A 802
LEU A 873
ARG A 880
PHE A 914
THR A1010
LEU A1014
ALA A1079
 URC  A3007 (-3.0A)
None
URC  A3007 (-3.7A)
URC  A3007 ( 3.4A)
URC  A3007 (-3.5A)
None
URC  A3007 (-3.4A)
 0.36A 3uniB-4yswA:
40.0		 3uniB-4yswA:
86.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 8 GLN A 918
PHE A 914
GLY A 915
GLY A 800
 BCT  A3006 (-3.0A)
URC  A3007 ( 3.4A)
BCT  A3006 (-3.9A)
None
 0.75A 3v3nB-4yswA:
undetectable		 3v3nB-4yswA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 8 GLN A 918
PHE A 914
GLY A 915
GLY A 800
 BCT  A3006 (-3.0A)
URC  A3007 ( 3.4A)
BCT  A3006 (-3.9A)
None
 0.74A 3v3nC-4yswA:
undetectable		 3v3nC-4yswA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 6 LEU A 964
PRO A1263
PHE A1005
GLU A1261
 None
None
None
URC  A3007 (-2.9A)
 1.28A 5b8iA-4yswA:
undetectable		 5b8iA-4yswA:
14.16