SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UQ5'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE
(Sus
scrofa) 		4 / 8 THR A 438
ILE A 421
VAL A 418
PRO A 362
 UQ5  A 612 (-3.0A)
None
None
None
 0.99A 1rxcE-2gmhA:
undetectable		 1rxcE-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE
(Sus
scrofa) 		4 / 8 THR A 438
ILE A 421
VAL A 418
PRO A 362
 UQ5  A 612 (-3.0A)
None
None
None
 0.97A 1rxcI-2gmhA:
undetectable		 1rxcI-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE
(Sus
scrofa) 		5 / 10 ILE A 123
GLY A 115
PHE A 114
GLY A 263
THR A 118
 None
None
UQ5  A 612 (-4.1A)
None
None
 1.18A 2y7wB-2gmhA:
0.9		 2y7wB-2gmhA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE
(Sus
scrofa) 		4 / 8 THR A 438
ILE A 421
VAL A 418
PRO A 362
 UQ5  A 612 (-3.0A)
None
None
None
 0.95A 4e1vE-2gmhA:
undetectable		 4e1vE-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE
(Sus
scrofa) 		4 / 8 THR A 438
ILE A 421
VAL A 418
PRO A 362
 UQ5  A 612 (-3.0A)
None
None
None
 1.01A 4e1vH-2gmhA:
undetectable		 4e1vH-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE
(Sus
scrofa) 		4 / 7 LEU A 294
GLU A 306
ILE A 364
VAL A 291
 None
None
UQ5  A 612 ( 4.8A)
UQ5  A 612 ( 4.9A)
 1.21A 5jh7C-2gmhA:
undetectable		 5jh7C-2gmhA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE
(Sus
scrofa) 		4 / 7 ASP A 459
GLY A 272
GLY A 293
VAL A 291
 None
UQ5  A 612 (-3.3A)
None
UQ5  A 612 ( 4.9A)
 0.98A 6ekzA-2gmhA:
undetectable		 6ekzA-2gmhA:
9.68