SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UQ1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3R6W_A_NFZA213_1 (FMN-DEPENDENT NADH-AZOREDUCTASE 1)	4n9q	FMN-DEPENDENT NADH-AZOREDUCTASE 1 (Pseudomonas aeruginosa)	5 / 10	PHE A 60 VAL A 114 PHE A 120 TYR A 131 PHE A 173	UQ1 A 302 (-4.4A) None UQ1 A 302 (-3.9A) UQ1 A 302 (-3.7A) UQ1 A 302 (-3.0A)	0.44A	3r6wA-4n9qA: 35.7 3r6wB-4n9qA: 34.2	3r6wA-4n9qA: 100.00 3r6wB-4n9qA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3R6W_A_NFZA214_1 (FMN-DEPENDENT NADH-AZOREDUCTASE 1)	4n9q	FMN-DEPENDENT NADH-AZOREDUCTASE 1 (Pseudomonas aeruginosa)	5 / 10	PHE A 60 VAL A 114 PHE A 120 TYR A 131 PHE A 173	UQ1 A 302 (-4.4A) None UQ1 A 302 (-3.9A) UQ1 A 302 (-3.7A) UQ1 A 302 (-3.0A)	0.13A	3r6wA-4n9qA: 35.7 3r6wB-4n9qA: 34.2	3r6wA-4n9qA: 100.00 3r6wB-4n9qA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KSZ_A_CYSA620_0 (LACTOPEROXIDASE)	2zup	DISULFIDE BOND FORMATION PROTEIN B (Escherichia coli)	3 / 3	ARG B 48 GLU B 47 PHE B 150	UQ1 B 177 (-4.5A) UQ1 B 177 (-3.5A) None	0.87A	4kszA-2zupB: undetectable	4kszA-2zupB: 14.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3R6W_A_NFZA213_1","FMN-DEPENDENT NADH-AZOREDUCTASE 1;FMN-DEPENDENT NADH-AZOREDUCTASE 1","4n9q","FMN-DEPENDENT NADH-AZOREDUCTASE 1","Pseudomonas aeruginosa",5,"PHE A  60;VAL A 114;PHE A 120;TYR A 131;PHE A 173","UQ1 A 302 (-4.4A);None;UQ1 A 302 (-3.9A);UQ1 A 302 (-3.7A);UQ1 A 302 (-3.0A)","0.44A","3r6wA-4n9qA:35.7;3r6wB-4n9qA:34.2",null],["3R6W_A_NFZA214_1","FMN-DEPENDENT NADH-AZOREDUCTASE 1;FMN-DEPENDENT NADH-AZOREDUCTASE 1","4n9q","FMN-DEPENDENT NADH-AZOREDUCTASE 1","Pseudomonas aeruginosa",5,"PHE A  60;VAL A 114;PHE A 120;TYR A 131;PHE A 173","UQ1 A 302 (-4.4A);None;UQ1 A 302 (-3.9A);UQ1 A 302 (-3.7A);UQ1 A 302 (-3.0A)","0.13A","3r6wA-4n9qA:35.7;3r6wB-4n9qA:34.2","3r6wA-4n9qA:100.00;3r6wB-4n9qA:100.00"],["4KSZ_A_CYSA620_0","LACTOPEROXIDASE","2zup","DISULFIDE BOND FORMATION PROTEIN B","Escherichia coli",3,"ARG B  48;GLU B  47;PHE B 150","UQ1 B 177 (-4.5A);UQ1 B 177 (-3.5A);None","0.87A","4kszA-2zupB:undetectable","3r6wA-4n9qA:100.00;3r6wB-4n9qA:100.00"]]