SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UND'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 1y9l LIPOPROTEIN MXIM
(Shigella
flexneri) 		3 / 3 ALA A  74
VAL A  65
TRP A  54
 None
None
UND  A 150 (-3.6A)
 0.89A 1nt6A-1y9lA:
undetectable		 1nt6A-1y9lA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 1y9l LIPOPROTEIN MXIM
(Shigella
flexneri) 		3 / 3 ALA A  74
VAL A  65
TRP A  54
 None
None
UND  A 150 (-3.6A)
 0.89A 1nt6B-1y9lA:
undetectable		 1nt6B-1y9lA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1y9l LIPOPROTEIN MXIM
(Shigella
flexneri) 		4 / 7 PHE A  83
ILE A 128
LEU A 136
ALA A 103
 UND  A 150 ( 3.9A)
None
None
None
 0.78A 6b5vA-1y9lA:
undetectable
6b5vC-1y9lA:
undetectable		 6b5vA-1y9lA:
16.10
6b5vC-1y9lA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1y9l LIPOPROTEIN MXIM
(Shigella
flexneri) 		4 / 7 ALA A 103
PHE A  83
ILE A 128
LEU A 136
 None
UND  A 150 ( 3.9A)
None
None
 0.78A 6b5vA-1y9lA:
undetectable
6b5vB-1y9lA:
undetectable		 6b5vA-1y9lA:
16.10
6b5vB-1y9lA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1y9l LIPOPROTEIN MXIM
(Shigella
flexneri) 		4 / 7 PHE A  83
ILE A 128
LEU A 136
ALA A 103
 UND  A 150 ( 3.9A)
None
None
None
 0.78A 6b5vC-1y9lA:
undetectable
6b5vD-1y9lA:
undetectable		 6b5vC-1y9lA:
16.10
6b5vD-1y9lA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1y9l LIPOPROTEIN MXIM
(Shigella
flexneri) 		4 / 7 ALA A 103
PHE A  83
ILE A 128
LEU A 136
 None
UND  A 150 ( 3.9A)
None
None
 0.78A 6b5vB-1y9lA:
undetectable
6b5vD-1y9lA:
undetectable		 6b5vB-1y9lA:
16.10
6b5vD-1y9lA:
16.10