SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UN9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V81_A_NVPA901_1 (HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT)	4csw	CUPIN 4 FAMILY PROTEIN (Rhodothermus marinus)	4 / 8	VAL A 121 TYR A 123 TRP A 87 LEU A 57	None UN9 A1391 ( 4.8A) None None	0.89A	3v81A-4cswA: undetectable	3v81A-4cswA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V81_C_NVPC901_1 (HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT)	4csw	CUPIN 4 FAMILY PROTEIN (Rhodothermus marinus)	4 / 8	VAL A 121 TYR A 123 TRP A 87 LEU A 57	None UN9 A1391 ( 4.8A) None None	0.88A	3v81C-4cswA: undetectable	3v81C-4cswA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FAK_A_SAMA201_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H)	4csw	CUPIN 4 FAMILY PROTEIN (Rhodothermus marinus)	5 / 10	LEU A 32 ILE A 7 SER A 37 THR A 206 PHE A 207	None None UN9 A1392 ( 4.9A) None None	1.00A	4fakA-4cswA: undetectable	4fakA-4cswA: 17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PWD_C_NVPC901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	4csw	CUPIN 4 FAMILY PROTEIN (Rhodothermus marinus)	4 / 8	VAL A 121 TYR A 123 TRP A 87 LEU A 57	None UN9 A1391 ( 4.8A) None None	0.89A	4pwdC-4cswA: undetectable	4pwdC-4cswA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0B_A_NVPA901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	4csw	CUPIN 4 FAMILY PROTEIN (Rhodothermus marinus)	4 / 8	VAL A 121 TYR A 123 TRP A 87 LEU A 57	None UN9 A1391 ( 4.8A) None None	0.90A	4q0bA-4cswA: undetectable	4q0bA-4cswA: 21.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3V81_A_NVPA901_1","HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT","4csw","CUPIN 4 FAMILY PROTEIN","Rhodothermus marinus",4,"VAL A 121;TYR A 123;TRP A  87;LEU A  57","None;UN9 A1391 ( 4.8A);None;None","0.89A","3v81A-4cswA:undetectable",null],["3V81_C_NVPC901_1","HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT","4csw","CUPIN 4 FAMILY PROTEIN","Rhodothermus marinus",4,"VAL A 121;TYR A 123;TRP A  87;LEU A  57","None;UN9 A1391 ( 4.8A);None;None","0.88A","3v81C-4cswA:undetectable","3v81A-4cswA:21.69"],["4FAK_A_SAMA201_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H","4csw","CUPIN 4 FAMILY PROTEIN","Rhodothermus marinus",5,"LEU A  32;ILE A   7;SER A  37;THR A 206;PHE A 207","None;None;UN9 A1392 ( 4.9A);None;None","1.00A","4fakA-4cswA:undetectable","3v81C-4cswA:21.69"],["4PWD_C_NVPC901_1","HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","4csw","CUPIN 4 FAMILY PROTEIN","Rhodothermus marinus",4,"VAL A 121;TYR A 123;TRP A  87;LEU A  57","None;UN9 A1391 ( 4.8A);None;None","0.89A","4pwdC-4cswA:undetectable","4fakA-4cswA:17.16"],["4Q0B_A_NVPA901_1","HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","4csw","CUPIN 4 FAMILY PROTEIN","Rhodothermus marinus",4,"VAL A 121;TYR A 123;TRP A  87;LEU A  57","None;UN9 A1391 ( 4.8A);None;None","0.90A","4q0bA-4cswA:undetectable","4pwdC-4cswA:21.69"]]