SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UML'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UYU_B_CAMB1416_0 (CYTOCHROME P450-CAM)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	4 / 8	THR A 153 LEU A 188 VAL A 191 THR A 105	UML  A 598 (-4.6A) None None K  A 605 (-3.1A)	1.18A	1uyuB-4c13A: undetectable	1uyuB-4c13A: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QOW_A_SAMA417_1 (HISTONE-LYSINE N-METHYLTRANSFERASE)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	3 / 3	THR A 404 ASP A 475 GLU A 460	None None UML  A 598 (-3.1A)	0.65A	3qowA-4c13A: 2.4	3qowA-4c13A: 23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BB2_B_STRB1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	5 / 11	ALA A  41 SER A  42 GLN A  21 THR A  77 ILE A  38	None UML  A 598 ( 3.8A) None None None	1.38A	4bb2A-4c13A: undetectable 4bb2B-4c13A: undetectable	4bb2A-4c13A: 21.61 4bb2B-4c13A: 6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L39_A_SALA602_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	4 / 6	TYR A 351 ARG A 335 THR A 115 GLY A 136	UML  A 598 ( 4.3A) PO4  A 601 (-3.9A) MG  A 503 ( 3.7A) None	1.02A	4l39A-4c13A: undetectable	4l39A-4c13A: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGF_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	4 / 6	THR A 152 GLU A 177 THR A 153 HIS A 209	UML  A 598 (-4.0A) MG  A 503 (-2.8A) UML  A 598 (-4.6A) None	1.07A	4pgfA-4c13A: undetectable	4pgfA-4c13A: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_B_GCSB307_1 (CHITOSANASE)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	4 / 7	GLU A 460 THR A 137 THR A 152 HIS A 353	UML  A 598 (-3.1A) MG  A 503 (-3.3A) UML  A 598 (-4.0A) UML  A 598 ( 3.9A)	0.79A	4qwpB-4c13A: undetectable	4qwpB-4c13A: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XQE_A_AG2A505_1 (HOMOSPERMIDINE SYNTHASE)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	5 / 12	ALA A 380 ASN A 407 PRO A 408 GLU A 460 TYR A 462	UML  A 598 ( 4.1A) UML  A 598 (-4.5A) None UML  A 598 (-3.1A) None	1.42A	4xqeA-4c13A: 3.6	4xqeA-4c13A: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XQE_B_AG2B504_1 (HOMOSPERMIDINE SYNTHASE)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	5 / 12	ALA A 380 ASN A 407 PRO A 408 GLU A 460 TYR A 462	UML  A 598 ( 4.1A) UML  A 598 (-4.5A) None UML  A 598 (-3.1A) None	1.44A	4xqeB-4c13A: 3.7	4xqeB-4c13A: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XRG_B_AG2B502_1 (HOMOSPERMIDINE SYNTHASE)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	5 / 12	ALA A 380 ASN A 407 PRO A 408 GLU A 460 TYR A 462	UML  A 598 ( 4.1A) UML  A 598 (-4.5A) None UML  A 598 (-3.1A) None	1.42A	4xrgB-4c13A: undetectable	4xrgB-4c13A: 23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FA8_A_SAMA301_1 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	3 / 3	THR A 404 ASP A 475 GLU A 460	None None UML  A 598 (-3.1A)	0.59A	5fa8A-4c13A: 4.0	5fa8A-4c13A: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YBB_A_SAMA601_1 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	4c13	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--L-LYSINE LIGASE (Staphylococcus aureus)	4 / 5	THR A 404 ASP A 475 GLU A 460 ASN A 138	None None UML  A 598 (-3.1A) None	1.39A	5ybbA-4c13A: 2.2	5ybbA-4c13A: 22.41