SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UE1'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		5 / 12 GLY A 671
ASN A 489
SER A 492
LEU A 484
LEU A 646
 UE1  A 998 (-3.4A)
UE1  A 998 (-2.8A)
None
None
None
 1.26A 1lhuA-3ue1A:
undetectable		 1lhuA-3ue1A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.72A 3ny4A-3ue1A:
15.8		 3ny4A-3ue1A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
ASN A 489
LYS A 669
THR A 670
GLY A 671
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 (-2.8A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
 0.80A 3sh8A-3ue1A:
16.1		 3sh8A-3ue1A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 487
ASN A 489
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-3.3A)
UE1  A 998 (-2.8A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.80A 4euzA-3ue1A:
16.2		 4euzA-3ue1A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		5 / 10 SER A 487
ASN A 489
LYS A 669
THR A 670
GLY A 671
 UE1  A 998 (-3.3A)
UE1  A 998 (-2.8A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
 0.69A 4fh2A-3ue1A:
17.0		 4fh2A-3ue1A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		4 / 7 ARG A 294
ALA A 290
GLY A 709
THR A 435
 None
None
UE1  A 998 (-3.9A)
None
 0.78A 5bs8A-3ue1A:
undetectable
5bs8C-3ue1A:
undetectable
5bs8D-3ue1A:
undetectable		 5bs8A-3ue1A:
21.90
5bs8C-3ue1A:
21.90
5bs8D-3ue1A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		4 / 6 ALA A 290
GLY A 709
THR A 435
ARG A 294
 None
UE1  A 998 (-3.9A)
None
None
 0.77A 5btgA-3ue1A:
undetectable
5btgB-3ue1A:
undetectable
5btgC-3ue1A:
undetectable		 5btgA-3ue1A:
21.90
5btgB-3ue1A:
18.27
5btgC-3ue1A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		4 / 7 ARG A 294
ALA A 290
GLY A 709
THR A 435
 None
None
UE1  A 998 (-3.9A)
None
 0.83A 5btgA-3ue1A:
undetectable
5btgC-3ue1A:
undetectable
5btgD-3ue1A:
undetectable		 5btgA-3ue1A:
21.90
5btgC-3ue1A:
21.90
5btgD-3ue1A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.60A 6b5yB-3ue1A:
5.5		 6b5yB-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.60A 6b5yD-3ue1A:
15.8		 6b5yD-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.67A 6b68B-3ue1A:
15.7		 6b68B-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		5 / 12 SER A 434
SER A 487
LYS A 669
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.70A 6b68D-3ue1A:
14.7		 6b68D-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.72A 6b69A-3ue1A:
15.8
6b69B-3ue1A:
14.7		 6b69A-3ue1A:
7.87
6b69B-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.71A 6b69D-3ue1A:
6.6		 6b69D-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.69A 6b6aB-3ue1A:
15.8		 6b6aB-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.70A 6b6aD-3ue1A:
14.7		 6b6aD-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.72A 6b6cA-3ue1A:
15.8		 6b6cA-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.67A 6b6dA-3ue1A:
15.6		 6b6dA-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.74A 6b6eA-3ue1A:
15.9		 6b6eA-3ue1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 3ue1 PENICILLIN-BINDING
PROTEIN 1A
(Acinetobacter
baumannii) 		6 / 12 SER A 434
SER A 487
LYS A 669
THR A 670
GLY A 671
THR A 672
 UE1  A 998 (-1.7A)
UE1  A 998 (-3.3A)
UE1  A 998 ( 3.8A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.4A)
UE1  A 998 (-3.6A)
 0.76A 6b6fA-3ue1A:
15.7		 6b6fA-3ue1A:
7.87