SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UDP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 4 HIS A 361
LEU A 286
LEU A 350
LEU A 245
 UDP  A 501 (-3.9A)
None
None
None
 1.19A 1a4lD-6bk1A:
undetectable		 1a4lD-6bk1A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 HIS A 139
ILE A 239
LEU A 409
ASP A 376
GLY A 377
 None
None
None
UDP  A 501 ( 4.5A)
None
 1.14A 1axwA-5v0tA:
undetectable		 1axwA-5v0tA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		5 / 10 GLY A 292
ALA A 297
ILE A 293
GLY A 357
SER A 299
 UDP  A1377 (-3.1A)
None
None
None
CL  A1379 ( 4.6A)
 1.19A 1c9sN-1f6dA:
undetectable
1c9sO-1f6dA:
undetectable		 1c9sN-1f6dA:
12.35
1c9sO-1f6dA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		5 / 9 GLY A 292
ALA A 297
ILE A 293
GLY A 357
SER A 299
 UDP  A1377 (-3.1A)
None
None
None
CL  A1379 ( 4.6A)
 1.19A 1c9sQ-1f6dA:
undetectable
1c9sR-1f6dA:
undetectable		 1c9sQ-1f6dA:
12.35
1c9sR-1f6dA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		5 / 10 GLY A 357
SER A 299
GLY A 292
ALA A 297
ILE A 293
 None
CL  A1379 ( 4.6A)
UDP  A1377 (-3.1A)
None
None
 1.19A 1c9sL-1f6dA:
undetectable
1c9sV-1f6dA:
undetectable		 1c9sL-1f6dA:
12.35
1c9sV-1f6dA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 6 LEU A 324
ILE A 255
ARG A 269
TRP A 271
 None
None
UDP  A 353 (-3.9A)
None
 1.06A 1db1A-1jiuA:
0.0		 1db1A-1jiuA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 6 LEU A 262
ILE A 189
GLU A 275
PRO A 270
 None
None
UDP  A 401 (-2.7A)
NA  A 403 (-4.3A)
 1.13A 1ditH-6ejjA:
undetectable
1ditP-6ejjA:
undetectable		 1ditH-6ejjA:
15.81
1ditP-6ejjA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 1gz5 ALPHA-TREHALOSE-PHOS
PHATE SYNTHASE
(Escherichia
coli) 		4 / 8 GLN A 185
PRO A 224
GLU A 393
ASP A 361
 IMD  A 902 ( 4.7A)
None
None
UDP  A 900 ( 4.5A)
 1.17A 1dtlA-1gz5A:
undetectable		 1dtlA-1gz5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		5 / 12 ARG A 299
SER A 325
TYR A 268
LEU A 285
LEU A 277
 None
UDP  A 503 (-3.1A)
None
None
None
 1.44A 1e7wA-5u6sA:
5.4		 1e7wA-5u6sA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		5 / 12 GLY A 307
ALA A 308
SER A 311
GLY A 314
LEU A 315
 UDP  A1401 ( 3.9A)
UDP  A1401 (-4.3A)
None
None
None
 0.63A 1fe2A-2iyfA:
undetectable		 1fe2A-2iyfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		5 / 9 GLY A 292
ALA A 297
ILE A 293
GLY A 357
SER A 299
 UDP  A1377 (-3.1A)
None
None
None
CL  A1379 ( 4.6A)
 1.17A 1gtfR-1f6dA:
undetectable
1gtfS-1f6dA:
undetectable		 1gtfR-1f6dA:
12.35
1gtfS-1f6dA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		5 / 11 GLY A 292
ALA A 297
ILE A 293
GLY A 357
SER A 299
 UDP  A1377 (-3.1A)
None
None
None
CL  A1379 ( 4.6A)
 1.15A 1gtnT-1f6dA:
undetectable
1gtnU-1f6dA:
undetectable		 1gtnT-1f6dA:
12.35
1gtnU-1f6dA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 1fgg GLUCURONYLTRANSFERAS
E I
(Homo
sapiens) 		4 / 6 ASP A 196
ASN A 197
ASP A 194
TYR A  84
 MN  A 336 ( 1.8A)
MN  A 336 ( 4.5A)
UDP  A 337 (-3.6A)
UDP  A 337 (-3.7A)
 1.43A 1hpkA-1fggA:
0.0		 1hpkA-1fggA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 1v84 GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 1
(Homo
sapiens) 		4 / 6 ASP A 197
ASN A 198
ASP A 195
TYR A  93
 MN  A 501 ( 2.0A)
MN  A 501 ( 4.6A)
UDP  A 503 (-3.5A)
UDP  A 503 (-3.7A)
 1.39A 1hpkA-1v84A:
undetectable		 1hpkA-1v84A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 11 ARG A 280
HIS A 354
SER A 317
LEU A 281
LEU A 327
 UDP  A 501 (-3.8A)
None
G6P  A 502 ( 4.3A)
None
None
 1.41A 1hwkB-5huuA:
undetectable		 1hwkB-5huuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 11 ARG A 280
HIS A 354
SER A 317
LEU A 281
LEU A 327
 UDP  A 501 (-3.8A)
None
G6P  A 502 ( 4.3A)
None
None
 1.41A 1hwkA-5huuA:
undetectable		 1hwkA-5huuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE
(Homo
sapiens) 		4 / 8 ARG A 325
SER A 139
SER A 302
LYS A  24
 None
None
UDP  A 501 (-2.5A)
UDP  A 501 (-3.1A)
 1.22A 1hwkC-4zhtA:
undetectable		 1hwkC-4zhtA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 11 ARG A 280
HIS A 354
SER A 317
LEU A 281
LEU A 327
 UDP  A 501 (-3.8A)
None
G6P  A 502 ( 4.3A)
None
None
 1.40A 1hwkD-5huuA:
undetectable		 1hwkD-5huuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 11 ARG A 280
HIS A 354
SER A 317
LEU A 281
LEU A 327
 UDP  A 501 (-3.8A)
None
G6P  A 502 ( 4.3A)
None
None
 1.41A 1hwkC-5huuA:
undetectable		 1hwkC-5huuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE
(Homo
sapiens) 		4 / 8 ARG A 325
SER A 139
SER A 302
LYS A  24
 None
None
UDP  A 501 (-2.5A)
UDP  A 501 (-3.1A)
 1.21A 1hwkD-4zhtA:
undetectable		 1hwkD-4zhtA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE
(Actinobacillus
pleuropneumoniae) 		5 / 12 LEU A 549
ASP A 388
SER A 286
THR A 520
GLY A 370
 None
None
None
UDP  A 621 (-3.7A)
None
 1.31A 1ia0B-3q3hA:
undetectable		 1ia0B-3q3hA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 4 LEU A 324
ILE A 255
ARG A 269
TRP A 271
 None
None
UDP  A 353 (-3.9A)
None
 1.04A 1ie9A-1jiuA:
0.0		 1ie9A-1jiuA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3qkw NUCLEOTIDE SUGAR
SYNTHETASE-LIKE
PROTEIN
(Streptococcus
parasanguinis) 		4 / 7 TYR A 245
ILE A  13
HIS A 156
LEU A 218
 UDP  A 400 (-4.7A)
None
UDP  A 400 (-4.9A)
None
 1.09A 1j96B-3qkwA:
undetectable		 1j96B-3qkwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.32A 1k2rA-6bk1A:
undetectable
1k2rB-6bk1A:
undetectable		 1k2rA-6bk1A:
13.48
1k2rB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.33A 1k2rA-6bk1A:
undetectable
1k2rB-6bk1A:
undetectable		 1k2rA-6bk1A:
13.48
1k2rB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.32A 1k2sA-6bk1A:
undetectable
1k2sB-6bk1A:
undetectable		 1k2sA-6bk1A:
13.48
1k2sB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 8 SER A 363
ILE A  15
PHE A  51
MET A 184
 None
UDP  A 501 (-3.7A)
None
None
 1.15A 1kb9A-5dldA:
undetectable
1kb9C-5dldA:
undetectable
1kb9D-5dldA:
undetectable
1kb9E-5dldA:
undetectable		 1kb9A-5dldA:
24.33
1kb9C-5dldA:
22.08
1kb9D-5dldA:
20.05
1kb9E-5dldA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 1lzxA-6bk1A:
undetectable
1lzxB-6bk1A:
undetectable		 1lzxA-6bk1A:
13.48
1lzxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 1lzzA-6bk1A:
0.0
1lzzB-6bk1A:
undetectable		 1lzzA-6bk1A:
13.48
1lzzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 1m00A-6bk1A:
undetectable
1m00B-6bk1A:
undetectable		 1m00A-6bk1A:
13.48
1m00B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 GLY A 366
GLU A 372
SER A 369
TYR A 315
 TRS  A1478 ( 3.5A)
UDP  A1477 (-2.6A)
UDP  A1477 (-2.6A)
EDO  A1480 (-4.8A)
 0.96A 1maaD-2vg8A:
undetectable		 1maaD-2vg8A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 PHE A 363
GLU A 384
ARG A 356
HIS A 442
PRO A 243
 None
UDP  A 501 (-2.8A)
None
None
FMT  A 509 ( 4.6A)
 1.29A 1mj2C-5v0tA:
undetectable
1mj2D-5v0tA:
undetectable		 1mj2C-5v0tA:
11.56
1mj2D-5v0tA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 371
SER A 373
LEU A 353
THR A 140
HIS A 364
 None
None
None
TRS  A1478 ( 4.4A)
UDP  A1477 (-3.9A)
 1.35A 1mmtA-2vg8A:
undetectable		 1mmtA-2vg8A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.32A 1mmwA-6bk1A:
undetectable
1mmwB-6bk1A:
undetectable		 1mmwA-6bk1A:
13.48
1mmwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 5enz UDP-GLCNAC
2-EPIMERASE
(Staphylococcus
aureus) 		4 / 6 ASN A 346
GLY A 284
ILE A 285
ILE A 175
 None
UDP  A 401 (-3.5A)
None
None
 0.78A 1n49D-5enzA:
undetectable		 1n49D-5enzA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		3 / 3 ASN A 133
ALA A 308
ASN A 333
 ERY  A1400 (-3.6A)
UDP  A1401 (-4.3A)
None
 0.71A 1n4fA-2iyfA:
undetectable		 1n4fA-2iyfA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		5 / 12 ILE A  55
GLY A  62
VAL A  65
SER A 144
GLY A  38
 None
UDP  A 196 ( 4.1A)
UDP  A 196 (-3.7A)
None
UDP  A 196 (-3.6A)
 1.10A 1nbhB-4ukdA:
undetectable		 1nbhB-4ukdA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		5 / 12 ILE A  55
GLY A  62
VAL A  65
SER A 144
GLY A  38
 None
UDP  A 196 ( 4.1A)
UDP  A 196 (-3.7A)
None
UDP  A 196 (-3.6A)
 1.05A 1nbiA-4ukdA:
undetectable		 1nbiA-4ukdA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		5 / 12 ILE A  55
GLY A  62
VAL A  65
SER A 144
GLY A  38
 None
UDP  A 196 ( 4.1A)
UDP  A 196 (-3.7A)
None
UDP  A 196 (-3.6A)
 1.07A 1nbiB-4ukdA:
undetectable		 1nbiB-4ukdA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 6 PHE E  73
ARG E  72
ILE E  80
TRP E  65
 None
None
None
UDP  E 403 (-4.0A)
 1.46A 1nsiA-5xykE:
undetectable
1nsiB-5xykE:
undetectable		 1nsiA-5xykE:
11.53
1nsiB-5xykE:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 6 ARG E  72
ILE E  80
TRP E  65
PHE E  73
 None
None
UDP  E 403 (-4.0A)
None
 1.44A 1nsiC-5xykE:
undetectable
1nsiD-5xykE:
undetectable		 1nsiC-5xykE:
11.53
1nsiD-5xykE:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 6 PHE E  73
ARG E  72
ILE E  80
TRP E  65
 None
None
None
UDP  E 403 (-4.0A)
 1.46A 1nsiC-5xykE:
undetectable
1nsiD-5xykE:
undetectable		 1nsiC-5xykE:
11.53
1nsiD-5xykE:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 1om4A-6bk1A:
undetectable
1om4B-6bk1A:
undetectable		 1om4A-6bk1A:
13.48
1om4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 1om4A-6bk1A:
undetectable
1om4B-6bk1A:
undetectable		 1om4A-6bk1A:
13.48
1om4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 1om5A-6bk1A:
undetectable
1om5B-6bk1A:
undetectable		 1om5A-6bk1A:
13.48
1om5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		5 / 12 ARG A 299
SER A 325
TYR A 268
LEU A 285
LEU A 277
 None
UDP  A 503 (-3.1A)
None
None
None
 1.44A 1p33B-5u6sA:
2.7		 1p33B-5u6sA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_D_MTXD354_1
(PTERIDINE REDUCTASE
1)		 4irq BETA-1,4-GALACTOSYLT
RANSFERASE 7
(Homo
sapiens) 		5 / 12 SER A 152
PRO A 100
LEU A 119
MET A 115
TYR A 175
 None
UDP  A 402 (-4.2A)
None
None
None
 1.46A 1p33D-4irqA:
undetectable		 1p33D-4irqA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 1p6hA-6bk1A:
undetectable
1p6hB-6bk1A:
undetectable		 1p6hA-6bk1A:
13.48
1p6hB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 1p6iA-6bk1A:
undetectable
1p6iB-6bk1A:
undetectable		 1p6iA-6bk1A:
13.48
1p6iB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.32A 1p6iA-6bk1A:
undetectable
1p6iB-6bk1A:
undetectable		 1p6iA-6bk1A:
13.48
1p6iB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 1p6kA-6bk1A:
0.0
1p6kB-6bk1A:
undetectable		 1p6kA-6bk1A:
13.48
1p6kB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1gy8 UDP-GALACTOSE
4-EPIMERASE
(Trypanosoma
brucei) 		3 / 3 VAL A 271
ALA A 203
HIS A 221
 None
NAD  A1382 (-3.5A)
UDP  A1383 (-4.2A)
 0.77A 1q23C-1gy8A:
0.0		 1q23C-1gy8A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1gy8 UDP-GALACTOSE
4-EPIMERASE
(Trypanosoma
brucei) 		3 / 3 VAL A 271
ALA A 203
HIS A 221
 None
NAD  A1382 (-3.5A)
UDP  A1383 (-4.2A)
 0.75A 1q23H-1gy8A:
0.0		 1q23H-1gy8A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1gy8 UDP-GALACTOSE
4-EPIMERASE
(Trypanosoma
brucei) 		3 / 3 VAL A 271
ALA A 203
HIS A 221
 None
NAD  A1382 (-3.5A)
UDP  A1383 (-4.2A)
 0.72A 1q23G-1gy8A:
0.0		 1q23G-1gy8A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 4phs PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)
(Streptococcus
parasanguinis) 		5 / 11 LEU A 200
ALA A 176
VAL A 146
LEU A 144
TYR A 180
 UDP  A 301 (-4.5A)
UDP  A 301 (-3.3A)
None
None
None
 1.16A 1rlbF-4phsA:
undetectable		 1rlbF-4phsA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE
(Homo
sapiens) 		4 / 7 PHE A 284
PHE A 287
SER A 302
ARG A 306
 UDP  A 501 (-4.8A)
UDP  A 501 (-3.4A)
UDP  A 501 (-2.5A)
None
 1.49A 1rqpB-4zhtA:
undetectable		 1rqpB-4zhtA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.32A 1rs6A-6bk1A:
undetectable
1rs6B-6bk1A:
undetectable		 1rs6A-6bk1A:
13.48
1rs6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.33A 1rs6A-6bk1A:
undetectable
1rs6B-6bk1A:
undetectable		 1rs6A-6bk1A:
13.48
1rs6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 1rs7A-6bk1A:
undetectable
1rs7B-6bk1A:
undetectable		 1rs7A-6bk1A:
13.48
1rs7B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.32A 1rs7A-6bk1A:
undetectable
1rs7B-6bk1A:
undetectable		 1rs7A-6bk1A:
13.48
1rs7B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 LYS A 259
ILE A 143
THR A 267
 None
None
UDP  A 353 ( 4.6A)
 0.78A 1rx3A-1jiuA:
2.1		 1rx3A-1jiuA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 1gy8 UDP-GALACTOSE
4-EPIMERASE
(Trypanosoma
brucei) 		4 / 6 HIS A 221
LEU A 276
ILE A  12
SER A 140
 UDP  A1383 (-4.2A)
None
NAD  A1382 (-3.8A)
NAD  A1382 (-3.9A)
 1.19A 1sbrA-1gy8A:
undetectable
1sbrB-1gy8A:
0.0		 1sbrA-1gy8A:
19.80
1sbrB-1gy8A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4dsh UDP-GALACTOPYRANOSE
MUTASE
(Trypanosoma
cruzi) 		4 / 6 PHE A 144
PHE A 102
ASN A 105
ASN A 157
 None
None
None
UDP  A 501 (-2.7A)
 1.46A 1t9uA-4dshA:
2.4		 1t9uA-4dshA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		3 / 3 SER A  17
GLY A  16
ARG A  93
 ADP  A 195 (-3.7A)
ADP  A 195 ( 3.4A)
UDP  A 196 (-2.9A)
 0.63A 1t9wA-4ukdA:
undetectable		 1t9wA-4ukdA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE
(Actinobacillus
pleuropneumoniae) 		5 / 12 LEU A 549
ASP A 388
SER A 286
THR A 520
GLY A 370
 None
None
None
UDP  A 621 (-3.7A)
None
 1.31A 1tubB-3q3hA:
undetectable		 1tubB-3q3hA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5enz UDP-GLCNAC
2-EPIMERASE
(Staphylococcus
aureus) 		4 / 7 THR A 280
THR A 203
VAL A 265
MET A 178
 None
UDP  A 401 ( 4.4A)
UDP  A 401 (-3.7A)
None
 1.12A 1tv8A-5enzA:
3.2		 1tv8A-5enzA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5enz UDP-GLCNAC
2-EPIMERASE
(Staphylococcus
aureus) 		4 / 7 THR A 280
THR A 203
VAL A 265
MET A 178
 None
UDP  A 401 ( 4.4A)
UDP  A 401 (-3.7A)
None
 1.13A 1tv8B-5enzA:
undetectable		 1tv8B-5enzA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 ALA A 221
ILE A 220
ILE A 189
LEU A 313
MET A 200
 UDP  A 401 ( 4.0A)
None
None
None
None
 0.86A 1uduB-6ejjA:
undetectable		 1uduB-6ejjA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		5 / 10 GLY A 292
ALA A 297
ILE A 293
GLY A 357
SER A 299
 UDP  A1377 (-3.1A)
None
None
None
CL  A1379 ( 4.6A)
 1.16A 1utdU-1f6dA:
0.0
1utdV-1f6dA:
undetectable		 1utdU-1f6dA:
12.35
1utdV-1f6dA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		5 / 11 GLY A 357
SER A 299
GLY A 292
ALA A 297
ILE A 293
 None
CL  A1379 ( 4.6A)
UDP  A1377 (-3.1A)
None
None
 1.13A 1utdL-1f6dA:
undetectable
1utdV-1f6dA:
undetectable		 1utdL-1f6dA:
12.35
1utdV-1f6dA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5h60 TRANSFERASE
(Escherichia
coli) 		3 / 3 MET A 276
ASN A 256
GLN A  50
 None
None
UDP  A 401 (-4.6A)
 1.04A 1xoqB-5h60A:
undetectable		 1xoqB-5h60A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 ALA A 221
ILE A 220
ILE A 189
LEU A 313
MET A 200
 UDP  A 401 ( 4.0A)
None
None
None
None
 0.99A 1xozA-6ejjA:
undetectable		 1xozA-6ejjA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5tzk GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 4 LEU C 162
PRO C  71
ILE C   6
LEU C  79
 None
UDP  C 401 (-3.5A)
None
None
 1.13A 1ya4B-5tzkC:
undetectable		 1ya4B-5tzkC:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 4x7m TARM
(Staphylococcus
aureus) 		4 / 4 GLY A 356
SER A 325
VAL A 360
LEU A 379
 UDP  A 500 (-3.2A)
None
None
None
 1.35A 1yajB-4x7mA:
3.7		 1yajB-4x7mA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 5 TYR A 275
SER A 289
SER A 291
THR A 208
 UDP  A 402 (-4.0A)
UDP  A 402 (-3.7A)
UDP  A 402 (-3.3A)
UDP  A 402 ( 4.5A)
 1.43A 1yvpA-5xvsA:
4.7		 1yvpA-5xvsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.34A 1zvlA-6bk1A:
undetectable
1zvlB-6bk1A:
undetectable		 1zvlA-6bk1A:
12.53
1zvlB-6bk1A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 1zzqA-6bk1A:
undetectable
1zzqB-6bk1A:
undetectable		 1zzqA-6bk1A:
13.48
1zzqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		5 / 9 THR A 359
LEU A 363
HIS A 305
ALA A 323
LEU A 196
 None
None
UDP  A1401 (-4.0A)
None
None
 1.20A 2azqA-2iyfA:
undetectable		 2azqA-2iyfA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 SER A 373
PHE A 361
GLN A 349
GLU A 372
 None
None
UDP  A1477 (-3.3A)
UDP  A1477 (-2.6A)
 1.28A 2c8aA-2vg8A:
undetectable		 2c8aA-2vg8A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 1fgg GLUCURONYLTRANSFERAS
E I
(Homo
sapiens) 		5 / 11 LEU A 263
SER A 283
LEU A 284
LEU A 165
ARG A 161
 None
None
None
None
UDP  A 337 ( 4.5A)
 1.06A 2ceoA-1fggA:
0.0		 2ceoA-1fggA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 2d7i POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 10
(Homo
sapiens) 		4 / 8 GLY A 343
GLU A 345
THR A 220
ILE A 341
 NGA  A 702 (-3.4A)
NGA  A 702 (-2.9A)
UDP  A 705 ( 3.9A)
UDP  A 705 (-4.3A)
 0.86A 2dtjA-2d7iA:
undetectable
2dtjB-2d7iA:
undetectable		 2dtjA-2d7iA:
16.13
2dtjB-2d7iA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5enz UDP-GLCNAC
2-EPIMERASE
(Staphylococcus
aureus) 		4 / 8 THR A 280
THR A 203
VAL A 265
MET A 178
 None
UDP  A 401 ( 4.4A)
UDP  A 401 (-3.7A)
None
 1.14A 2fb2A-5enzA:
3.4		 2fb2A-5enzA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5enz UDP-GLCNAC
2-EPIMERASE
(Staphylococcus
aureus) 		4 / 7 THR A 280
THR A 203
VAL A 265
MET A 178
 None
UDP  A 401 ( 4.4A)
UDP  A 401 (-3.7A)
None
 1.18A 2fb2B-5enzA:
3.4		 2fb2B-5enzA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 2g6hA-6bk1A:
undetectable
2g6hB-6bk1A:
undetectable		 2g6hA-6bk1A:
13.48
2g6hB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 2g6hA-6bk1A:
undetectable
2g6hB-6bk1A:
undetectable		 2g6hA-6bk1A:
13.48
2g6hB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 2g6kA-6bk1A:
undetectable
2g6kB-6bk1A:
undetectable		 2g6kA-6bk1A:
13.48
2g6kB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 2g6kA-6bk1A:
undetectable
2g6kB-6bk1A:
undetectable		 2g6kA-6bk1A:
13.48
2g6kB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 2g6mA-6bk1A:
undetectable
2g6mB-6bk1A:
undetectable		 2g6mA-6bk1A:
13.48
2g6mB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 2g6mA-6bk1A:
undetectable
2g6mB-6bk1A:
undetectable		 2g6mA-6bk1A:
13.48
2g6mB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5hvm ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 12 TYR A 373
ILE A 380
VAL A 381
ALA A 321
VAL A 391
 None
None
None
None
UDP  A 601 (-4.0A)
 1.06A 2g72B-5hvmA:
undetectable		 2g72B-5hvmA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL E 132
ILE E  78
LEU E 120
ILE E  80
ALA E 240
 None
None
None
None
UDP  E 403 (-3.5A)
 1.15A 2gj5A-5xykE:
undetectable		 2gj5A-5xykE:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 7 ARG A 294
LEU A 299
PRO A 312
VAL A 309
 None
UDP  A 600 ( 4.3A)
None
None
 1.30A 2hrcA-3c4qA:
2.9		 2hrcA-3c4qA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 2hx3A-6bk1A:
undetectable
2hx3B-6bk1A:
undetectable		 2hx3A-6bk1A:
13.48
2hx3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 2hx3A-6bk1A:
undetectable
2hx3B-6bk1A:
undetectable		 2hx3A-6bk1A:
13.48
2hx3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 2hx4A-6bk1A:
undetectable
2hx4B-6bk1A:
undetectable		 2hx4A-6bk1A:
13.48
2hx4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		3 / 3 LEU A 581
LEU A 296
MET A 649
 None
UDP  A 901 (-3.7A)
None
 0.77A 2itzA-3s29A:
undetectable		 2itzA-3s29A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 5gvv GLYCOSYL TRANSFERASE
FAMILY 8
(Streptococcus
pneumoniae) 		5 / 12 LEU A 103
LEU A 109
ILE A  20
GLY A  12
LEU A  39
 None
None
None
UDP  A 502 (-3.0A)
None
 0.93A 2j7xA-5gvvA:
undetectable		 2j7xA-5gvvA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 ARG E  72
ILE E  80
TRP E  65
PHE E  73
 None
None
UDP  E 403 (-4.0A)
None
 1.47A 2nsiA-5xykE:
undetectable
2nsiB-5xykE:
undetectable		 2nsiA-5xykE:
11.53
2nsiB-5xykE:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 PHE E  73
ARG E  72
ILE E  80
TRP E  65
 None
None
None
UDP  E 403 (-4.0A)
 1.44A 2nsiA-5xykE:
undetectable
2nsiB-5xykE:
undetectable		 2nsiA-5xykE:
11.53
2nsiB-5xykE:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 ARG E  72
ILE E  80
TRP E  65
PHE E  73
 None
None
UDP  E 403 (-4.0A)
None
 1.44A 2nsiC-5xykE:
undetectable
2nsiD-5xykE:
undetectable		 2nsiC-5xykE:
11.53
2nsiD-5xykE:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 PHE E  73
ARG E  72
ILE E  80
TRP E  65
 None
None
None
UDP  E 403 (-4.0A)
 1.46A 2nsiC-5xykE:
undetectable
2nsiD-5xykE:
undetectable		 2nsiC-5xykE:
11.53
2nsiD-5xykE:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		3 / 3 SER A 333
HIS A 368
ASP A 372
 UDP  A1424 (-2.7A)
None
None
 0.72A 2oxtA-2iyaA:
2.4		 2oxtA-2iyaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		4 / 5 SER A 333
GLY A 263
HIS A 368
ASP A 372
 UDP  A1424 (-2.7A)
UDP  A1424 ( 3.9A)
None
None
 1.11A 2oxtB-2iyaA:
2.5		 2oxtB-2iyaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 LEU A 289
GLY A 320
VAL A 337
ALA A 299
LEU A 300
 None
None
None
UDP  A1001 ( 3.7A)
None
 1.18A 2oz7A-4whmA:
undetectable		 2oz7A-4whmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 4 VAL A 302
THR A 284
VAL A 289
GLY A 288
 None
None
None
UDP  A1081 (-3.7A)
 1.18A 2p2fB-3beoA:
2.5		 2p2fB-3beoA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		4 / 4 VAL A 300
THR A 282
VAL A 287
GLY A 286
 None
None
UDP  A 402 ( 4.9A)
UDP  A 402 (-3.5A)
 1.16A 2p2fB-4fkzA:
4.7		 2p2fB-4fkzA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 8 LEU A 232
ARG A 294
LEU A 299
PRO A 312
VAL A 309
 None
None
UDP  A 600 ( 4.3A)
None
None
 1.47A 2po5B-3c4qA:
3.4		 2po5B-3c4qA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 353
GLN A 349
VAL A 273
MET A 427
LEU A 271
 None
UDP  A1477 (-3.3A)
None
None
None
 1.33A 2q7kA-2vg8A:
undetectable		 2q7kA-2vg8A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 12 GLU A 293
ARG A 311
ILE A  14
ASP A  95
GLU A 117
 None
None
UDP  A 401 (-3.8A)
UD1  A 400 ( 4.8A)
None
 1.29A 2qeoA-4nesA:
undetectable		 2qeoA-4nesA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3cv3 GLUCURONOSYLTRANSFER
ASE GUMK
(Xanthomonas
campestris) 		4 / 6 TYR A 292
ALA A 302
ARG A 331
PRO A 321
 UDP  A1081 (-4.5A)
None
None
None
 1.30A 2ql8A-3cv3A:
undetectable
2ql8B-3cv3A:
undetectable		 2ql8A-3cv3A:
17.96
2ql8B-3cv3A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 9 LEU A 253
ILE A 250
GLY A 210
SER A 258
LEU A 204
 None
UDP  A 402 (-4.0A)
EDO  A 404 ( 4.8A)
None
None
 1.12A 2qmmA-6bwlA:
undetectable		 2qmmA-6bwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 8 ILE A 272
LEU A 178
LEU A  16
GLY A  15
 UDP  A 402 (-4.6A)
None
None
None
 0.93A 2qqdB-5xvsA:
undetectable
2qqdC-5xvsA:
undetectable		 2qqdB-5xvsA:
21.62
2qqdC-5xvsA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 10 SER A 385
ALA A 407
ASN A 382
ALA A 405
ALA A 408
 None
None
UDP  A 501 ( 4.0A)
None
None
 1.14A 2r2vC-5huuA:
undetectable
2r2vF-5huuA:
undetectable
2r2vG-5huuA:
undetectable		 2r2vC-5huuA:
5.24
2r2vF-5huuA:
5.24
2r2vG-5huuA:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 5hvo ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		5 / 10 SER A 392
ALA A 414
ASN A 389
ALA A 412
ALA A 415
 None
None
UDP  A 501 ( 3.7A)
None
None
 1.18A 2r2vC-5hvoA:
undetectable
2r2vF-5hvoA:
undetectable
2r2vG-5hvoA:
undetectable		 2r2vC-5hvoA:
5.65
2r2vF-5hvoA:
5.65
2r2vG-5hvoA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_B_PPFB3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 7 ARG A 265
HIS A  91
SER A 269
ASP A 364
 UDP  A 501 (-3.9A)
None
None
GOL  A 504 (-3.3A)
 1.50A 2rk8B-5tvgA:
undetectable		 2rk8B-5tvgA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 7 PHE A 576
ILE A 574
THR A 680
GLY A 610
 None
None
UDP  A 901 (-3.2A)
None
 0.62A 2v0mB-3s29A:
undetectable		 2v0mB-3s29A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1xv5 DNA
ALPHA-GLUCOSYLTRANSF
ERASE
(Escherichia
virus
T4) 		5 / 8 HIS A1114
SER A1020
ASN A1081
ILE A1005
TYR A1307
 GOL  A2002 (-3.6A)
None
None
None
UDP  A1402 (-4.7A)
 1.49A 2v57A-1xv5A:
undetectable		 2v57A-1xv5A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1xv5 DNA
ALPHA-GLUCOSYLTRANSF
ERASE
(Escherichia
virus
T4) 		5 / 8 HIS A1114
SER A1020
ASN A1081
ILE A1005
TYR A1307
 GOL  A2002 (-3.6A)
None
None
None
UDP  A1402 (-4.7A)
 1.49A 2v57C-1xv5A:
undetectable		 2v57C-1xv5A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE
(Homo
sapiens) 		4 / 7 PHE A 284
PHE A 287
SER A 302
ARG A 306
 UDP  A 501 (-4.8A)
UDP  A 501 (-3.4A)
UDP  A 501 (-2.5A)
None
 1.48A 2v7uB-4zhtA:
undetectable		 2v7uB-4zhtA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		3 / 3 TRP A 312
GLN A 311
TRP A  79
 UDP  A1424 (-3.6A)
None
ZIO  A1425 (-3.8A)
 1.28A 2vqyA-2iyaA:
undetectable		 2vqyA-2iyaA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3cv3 GLUCURONOSYLTRANSFER
ASE GUMK
(Xanthomonas
campestris) 		3 / 3 LEU A 316
TYR A 311
GLN A 310
 None
None
UDP  A1081 (-4.6A)
 0.75A 2wekA-3cv3A:
4.8		 2wekA-3cv3A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 2jcj N-ACETYLLACTOSAMINID
E
ALPHA-1,3-GALACTOSYL
TRANSFERASE
(Bos
taurus) 		4 / 5 VAL A 136
TYR A 139
VAL A 226
ASP A 225
 UDP  A1366 (-3.8A)
UDP  A1366 (-3.4A)
UDP  A1366 (-4.1A)
MN  A1367 ( 3.1A)
 1.22A 2x45A-2jcjA:
undetectable		 2x45A-2jcjA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 2ffu POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 2
(Homo
sapiens) 		5 / 12 ALA A 148
GLU A 147
PHE A 361
SER A 225
THR A 155
 None
None
None
UDP  A 601 (-2.9A)
None
 1.28A 2xffA-2ffuA:
0.0		 2xffA-2ffuA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 5ndf POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 2
(Homo
sapiens) 		5 / 12 ALA A 148
GLU A 147
PHE A 361
SER A 225
THR A 155
 None
None
LU2  A 608 ( 3.4A)
UDP  A 602 (-2.9A)
None
 1.28A 2xffA-5ndfA:
undetectable		 2xffA-5ndfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1v84 GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 1
(Homo
sapiens) 		4 / 6 HIS A 311
ALA A 256
ALA A 194
THR A  90
 UDP  A 503 (-4.2A)
None
None
None
 0.93A 2xfhA-1v84A:
undetectable		 2xfhA-1v84A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 2d7i POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 10
(Homo
sapiens) 		3 / 3 ARG A 221
GLU A 340
SER A 238
 NGA  A 702 (-3.6A)
None
UDP  A 705 (-2.8A)
 0.94A 2xkkA-2d7iA:
1.7
2xkkC-2d7iA:
undetectable		 2xkkA-2d7iA:
20.46
2xkkC-2d7iA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 1fgg GLUCURONYLTRANSFERAS
E I
(Homo
sapiens) 		5 / 10 LEU A 263
SER A 283
LEU A 284
LEU A 165
ARG A 161
 None
None
None
None
UDP  A 337 ( 4.5A)
 1.12A 2xn7A-1fggA:
0.1
2xn7B-1fggA:
0.0		 2xn7A-1fggA:
20.85
2xn7B-1fggA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Pyrococcus
abyssi) 		5 / 12 ILE A 105
ALA A 163
GLY A 135
THR A 136
GLY A 140
 None
None
UDP  A 250 (-3.4A)
UDP  A 250 (-2.8A)
None
 1.06A 2y7hB-2pnzA:
undetectable		 2y7hB-2pnzA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Pyrococcus
abyssi) 		5 / 12 ILE A 105
ALA A 163
GLY A 135
THR A 136
GLY A 140
 None
None
UDP  A 250 (-3.4A)
UDP  A 250 (-2.8A)
None
 1.06A 2y7hC-2pnzA:
undetectable		 2y7hC-2pnzA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4w6q GLUCOSYLTRANSFERASE
(Streptococcus
agalactiae) 		5 / 12 THR A 196
GLY A 175
LEU A 202
PHE A 182
ILE A 183
 None
UDP  A 402 ( 4.8A)
None
None
None
 1.14A 2y7kD-4w6qA:
undetectable		 2y7kD-4w6qA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		4 / 5 GLN A  24
THR A  20
THR A 348
LEU A 331
 None
UDP  A 503 ( 4.3A)
None
None
 1.31A 2zj0A-5u6sA:
3.6		 2zj0A-5u6sA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 5 LEU A 324
ILE A 255
ARG A 269
TRP A 271
 None
None
UDP  A 353 (-3.9A)
None
 1.12A 2zlcA-1jiuA:
0.0		 2zlcA-1jiuA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4phs PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)
(Streptococcus
parasanguinis) 		5 / 10 GLU A 248
ARG A 116
GLY A  30
LEU A  51
ILE A  42
 None
UDP  A 301 (-4.1A)
None
None
None
 1.31A 3adsA-4phsA:
undetectable		 3adsA-4phsA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5v4a GLYCOSYLTRANSFERASE
(DUF1792)
(Streptococcus
sanguinis) 		5 / 10 GLU A 248
ARG A 116
GLY A  29
LEU A  50
ILE A  41
 None
UDP  A 301 (-4.1A)
None
None
None
 1.26A 3adsA-5v4aA:
undetectable		 3adsA-5v4aA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 9 LEU A 253
ILE A 250
GLY A 210
SER A 258
LEU A 204
 None
UDP  A 402 (-4.0A)
EDO  A 404 ( 4.8A)
None
None
 1.09A 3ai9X-6bwlA:
undetectable		 3ai9X-6bwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Pyrococcus
abyssi) 		4 / 8 VAL A 129
GLY A 135
THR A 136
ALA A 139
 None
UDP  A 250 (-3.4A)
UDP  A 250 (-2.8A)
None
 0.67A 3aruA-2pnzA:
undetectable		 3aruA-2pnzA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3b3mA-6bk1A:
undetectable
3b3mB-6bk1A:
undetectable		 3b3mA-6bk1A:
13.48
3b3mB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 3b3mA-6bk1A:
undetectable
3b3mB-6bk1A:
undetectable		 3b3mA-6bk1A:
13.48
3b3mB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.32A 3b3nA-6bk1A:
undetectable
3b3nB-6bk1A:
undetectable		 3b3nA-6bk1A:
13.48
3b3nB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 3b3oA-6bk1A:
undetectable
3b3oB-6bk1A:
undetectable		 3b3oA-6bk1A:
13.48
3b3oB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 3b3oA-6bk1A:
undetectable
3b3oB-6bk1A:
undetectable		 3b3oA-6bk1A:
13.48
3b3oB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3b3pA-6bk1A:
undetectable
3b3pB-6bk1A:
undetectable		 3b3pA-6bk1A:
13.48
3b3pB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3b3pA-6bk1A:
undetectable
3b3pB-6bk1A:
undetectable		 3b3pA-6bk1A:
13.48
3b3pB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		4 / 5 GLN A  24
THR A  20
THR A 348
LEU A 331
 None
UDP  A 503 ( 4.3A)
None
None
 1.32A 3ce6A-5u6sA:
undetectable		 3ce6A-5u6sA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		4 / 5 GLN A  24
THR A  20
THR A 348
LEU A 331
 None
UDP  A 503 ( 4.3A)
None
None
 1.34A 3ce6C-5u6sA:
undetectable		 3ce6C-5u6sA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A  51
GLY A 270
PHE A  48
VAL A 188
LEU A 277
 None
UDP  A 401 ( 4.7A)
None
None
None
 1.13A 3dh0B-4nesA:
3.0		 3dh0B-4nesA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 GLY A 230
PRO A  16
GLY A  22
GLY A  23
ILE A 261
 UDP  A 600 ( 4.0A)
UDP  A 600 (-4.0A)
UDP  A 600 ( 3.8A)
UDP  A 600 (-3.2A)
None
 0.91A 3douA-3c4qA:
4.5		 3douA-3c4qA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3dqrA-6bk1A:
undetectable
3dqrB-6bk1A:
undetectable		 3dqrA-6bk1A:
13.48
3dqrB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5y7f UGGT
(Thermomyces
dupontii) 		4 / 4 ILE A1271
GLN A1264
ILE A1227
LEU A1384
 UDP  A2001 (-4.1A)
None
None
None
 1.31A 3dzyD-5y7fA:
undetectable		 3dzyD-5y7fA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 11 LEU A  76
ALA A 227
ASP A 226
ASP A 228
ILE A  80
 MPD  A 506 ( 4.9A)
UDP  A 501 (-3.8A)
UDP  A 501 (-3.4A)
MG  A 503 ( 2.4A)
MPD  A 506 (-4.5A)
 1.14A 3ebzB-6dusA:
undetectable		 3ebzB-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 PHE E  73
ARG E  72
ILE E  80
TRP E  65
 None
None
None
UDP  E 403 (-4.0A)
 1.42A 3ej8A-5xykE:
undetectable
3ej8B-5xykE:
undetectable		 3ej8A-5xykE:
11.62
3ej8B-5xykE:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_C_H4BC3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 ARG E  72
ILE E  80
TRP E  65
PHE E  73
 None
None
UDP  E 403 (-4.0A)
None
 1.44A 3ej8C-5xykE:
undetectable
3ej8D-5xykE:
undetectable		 3ej8C-5xykE:
11.62
3ej8D-5xykE:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_D_H4BD4902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 PHE E  73
ARG E  72
ILE E  80
TRP E  65
 None
None
None
UDP  E 403 (-4.0A)
 1.46A 3ej8C-5xykE:
undetectable
3ej8D-5xykE:
undetectable		 3ej8C-5xykE:
11.62
3ej8D-5xykE:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		4 / 5 PRO A 714
THR A 680
VAL A 681
GLY A 678
 None
UDP  A 901 (-3.2A)
None
UDP  A 901 ( 3.7A)
 1.03A 3elzA-3s29A:
undetectable		 3elzA-3s29A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4irq BETA-1,4-GALACTOSYLT
RANSFERASE 7
(Homo
sapiens) 		5 / 12 TYR A 194
GLY A 223
GLU A 227
GLY A 225
HIS A 259
 UDP  A 402 (-4.6A)
None
TRS  A 403 (-2.5A)
TRS  A 403 (-3.2A)
MN  A 401 ( 3.4A)
 1.04A 3f8wB-4irqA:
undetectable		 3f8wB-4irqA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.33A 3fc5A-6bk1A:
undetectable
3fc5B-6bk1A:
undetectable		 3fc5A-6bk1A:
13.48
3fc5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.32A 3fc5A-6bk1A:
undetectable
3fc5B-6bk1A:
undetectable		 3fc5A-6bk1A:
13.48
3fc5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 3qkw NUCLEOTIDE SUGAR
SYNTHETASE-LIKE
PROTEIN
(Streptococcus
parasanguinis) 		5 / 12 THR A  16
LEU A  19
VAL A 229
MET A 153
VAL A 257
 UDP  A 400 (-3.0A)
None
None
None
None
 0.95A 3frqB-3qkwA:
undetectable		 3frqB-3qkwA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		5 / 12 ALA A 334
GLY A 332
LEU A 196
SER A 311
GLY A 307
 None
None
None
None
UDP  A1401 ( 3.9A)
 1.01A 3g2oA-2iyfA:
undetectable		 3g2oA-2iyfA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 VAL A  24
SER A 277
ILE A  42
ILE A  86
TYR A 386
 None
UDP  A1477 (-2.5A)
EDO  A1483 (-4.8A)
EDO  A1480 (-4.9A)
None
 1.26A 3g8iA-2vg8A:
undetectable		 3g8iA-2vg8A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 THR A 141
LEU A 396
ILE A 400
HIS A 364
TYR A 386
 None
None
None
UDP  A1477 (-3.9A)
None
 1.37A 3gwxB-2vg8A:
undetectable		 3gwxB-2vg8A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4irq BETA-1,4-GALACTOSYLT
RANSFERASE 7
(Homo
sapiens) 		4 / 8 ASP A 165
ASP A 163
ASP A 260
TYR A 194
 MN  A 401 ( 2.7A)
UDP  A 402 (-3.3A)
None
UDP  A 402 (-4.6A)
 1.12A 3havA-4irqA:
undetectable		 3havA-4irqA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_PNTA901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 TYR A 261
THR A  99
ASP A 100
GLY A 187
TYR A 186
 UDP  A 353 (-4.7A)
None
None
UDP  A 353 ( 4.2A)
None
 0.91A 3hiiA-1jiuA:
0.0		 3hiiA-1jiuA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 TYR A 261
THR A  99
ASP A 100
GLY A 187
TYR A 186
 UDP  A 353 (-4.7A)
None
None
UDP  A 353 ( 4.2A)
None
 0.90A 3hiiB-1jiuA:
0.0		 3hiiB-1jiuA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3hsnA-6bk1A:
undetectable
3hsnB-6bk1A:
undetectable		 3hsnA-6bk1A:
13.48
3hsnB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3hsnA-6bk1A:
undetectable
3hsnB-6bk1A:
undetectable		 3hsnA-6bk1A:
13.48
3hsnB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3hsoA-6bk1A:
undetectable
3hsoB-6bk1A:
undetectable		 3hsoA-6bk1A:
13.48
3hsoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3hsoA-6bk1A:
undetectable
3hsoB-6bk1A:
undetectable		 3hsoA-6bk1A:
13.48
3hsoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 3hspA-6bk1A:
undetectable
3hspB-6bk1A:
undetectable		 3hspA-6bk1A:
13.48
3hspB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 3hspA-6bk1A:
undetectable
3hspB-6bk1A:
undetectable		 3hspA-6bk1A:
13.48
3hspB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Pyrococcus
abyssi) 		4 / 4 GLY A 222
VAL A 226
GLY A 135
THR A 136
 MPD  A 252 ( 4.2A)
None
UDP  A 250 (-3.4A)
UDP  A 250 (-2.8A)
 0.88A 3ib2A-2pnzA:
undetectable		 3ib2A-2pnzA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		5 / 12 ILE A 200
GLY A 190
GLY A 189
ALA A 124
ALA A 183
 UDP  A 501 (-4.5A)
None
None
None
None
 1.08A 3jayA-5f84A:
undetectable		 3jayA-5f84A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 3jt3A-6bk1A:
undetectable
3jt3B-6bk1A:
undetectable		 3jt3A-6bk1A:
13.48
3jt3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3jt4A-6bk1A:
0.1
3jt4B-6bk1A:
undetectable		 3jt4A-6bk1A:
13.48
3jt4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3jt4A-6bk1A:
0.1
3jt4B-6bk1A:
undetectable		 3jt4A-6bk1A:
13.48
3jt4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3jt5A-6bk1A:
undetectable
3jt5B-6bk1A:
undetectable		 3jt5A-6bk1A:
13.48
3jt5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3jt5A-6bk1A:
undetectable
3jt5B-6bk1A:
undetectable		 3jt5A-6bk1A:
13.48
3jt5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3jt6A-6bk1A:
undetectable
3jt6B-6bk1A:
0.0		 3jt6A-6bk1A:
13.48
3jt6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3jt6A-6bk1A:
undetectable
3jt6B-6bk1A:
0.0		 3jt6A-6bk1A:
13.48
3jt6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3jt7A-6bk1A:
undetectable
3jt7B-6bk1A:
undetectable		 3jt7A-6bk1A:
13.48
3jt7B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3jt7A-6bk1A:
undetectable
3jt7B-6bk1A:
undetectable		 3jt7A-6bk1A:
13.48
3jt7B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 3jt8A-6bk1A:
undetectable
3jt8B-6bk1A:
undetectable		 3jt8A-6bk1A:
13.48
3jt8B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.32A 3jtaA-6bk1A:
undetectable
3jtaB-6bk1A:
0.0		 3jtaA-6bk1A:
13.48
3jtaB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3jwsA-6bk1A:
undetectable
3jwsB-6bk1A:
undetectable		 3jwsA-6bk1A:
13.48
3jwsB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3jwtA-6bk1A:
undetectable
3jwtB-6bk1A:
undetectable		 3jwtA-6bk1A:
13.48
3jwtB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 3jwtA-6bk1A:
undetectable
3jwtB-6bk1A:
undetectable		 3jwtA-6bk1A:
13.48
3jwtB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 3jwuA-6bk1A:
undetectable
3jwuB-6bk1A:
undetectable		 3jwuA-6bk1A:
13.48
3jwuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 3jwuA-6bk1A:
undetectable
3jwuB-6bk1A:
undetectable		 3jwuA-6bk1A:
13.48
3jwuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 3jwvA-6bk1A:
undetectable
3jwvB-6bk1A:
undetectable		 3jwvA-6bk1A:
13.48
3jwvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 3jwvA-6bk1A:
undetectable
3jwvB-6bk1A:
undetectable		 3jwvA-6bk1A:
13.48
3jwvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3jx0A-6bk1A:
undetectable
3jx0B-6bk1A:
undetectable		 3jx0A-6bk1A:
13.48
3jx0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3jx0A-6bk1A:
undetectable
3jx0B-6bk1A:
undetectable		 3jx0A-6bk1A:
13.48
3jx0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3jx1A-6bk1A:
0.0
3jx1B-6bk1A:
undetectable		 3jx1A-6bk1A:
13.48
3jx1B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3jx1A-6bk1A:
undetectable
3jx1B-6bk1A:
undetectable		 3jx1A-6bk1A:
13.48
3jx1B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3jx2A-6bk1A:
undetectable
3jx2B-6bk1A:
undetectable		 3jx2A-6bk1A:
13.48
3jx2B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3jx3A-6bk1A:
0.0
3jx3B-6bk1A:
undetectable		 3jx3A-6bk1A:
13.48
3jx3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3jx3A-6bk1A:
0.0
3jx3B-6bk1A:
undetectable		 3jx3A-6bk1A:
13.48
3jx3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3jx4A-6bk1A:
0.0
3jx4B-6bk1A:
undetectable		 3jx4A-6bk1A:
13.48
3jx4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3jx5A-6bk1A:
undetectable
3jx5B-6bk1A:
undetectable		 3jx5A-6bk1A:
13.48
3jx5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3jx6A-6bk1A:
0.0
3jx6B-6bk1A:
undetectable		 3jx6A-6bk1A:
13.48
3jx6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.11A 3keeA-3s29A:
undetectable		 3keeA-3s29A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Pyrococcus
abyssi) 		5 / 12 ARG A  21
GLY A  48
SER A  85
GLU A 179
ALA A 134
 None
None
None
None
UDP  A 250 (-4.1A)
 1.10A 3kkzA-2pnzA:
undetectable		 3kkzA-2pnzA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Pyrococcus
abyssi) 		5 / 12 ARG A  21
GLY A  48
SER A  85
GLU A 179
ALA A 134
 None
None
None
None
UDP  A 250 (-4.1A)
 1.10A 3kkzB-2pnzA:
undetectable		 3kkzB-2pnzA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 SER A 274
ILE A 343
CYH A 258
PHE A 361
SER A 369
 UDP  A1477 ( 3.7A)
None
None
None
UDP  A1477 (-2.6A)
 1.45A 3ko0G-2vg8A:
0.0
3ko0H-2vg8A:
undetectable
3ko0I-2vg8A:
0.0
3ko0J-2vg8A:
0.0		 3ko0G-2vg8A:
12.24
3ko0H-2vg8A:
12.24
3ko0I-2vg8A:
12.24
3ko0J-2vg8A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 SER A 274
ILE A 343
CYH A 258
SER A 369
PHE A 361
 UDP  A1477 ( 3.7A)
None
None
UDP  A1477 (-2.6A)
None
 1.40A 3ko0Q-2vg8A:
undetectable
3ko0R-2vg8A:
0.0
3ko0S-2vg8A:
0.0
3ko0T-2vg8A:
undetectable		 3ko0Q-2vg8A:
12.24
3ko0R-2vg8A:
12.24
3ko0S-2vg8A:
12.24
3ko0T-2vg8A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		5 / 12 PHE A 169
LEU A 383
MET A 381
GLY A 243
ALA A  37
 None
UDP  A 501 (-4.0A)
None
None
None
 1.31A 3lbdA-5huuA:
undetectable		 3lbdA-5huuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE
(Actinobacillus
pleuropneumoniae) 		4 / 6 TYR A 567
ASN A 519
ASP A 546
LYS A 536
 None
UDP  A 621 ( 4.9A)
None
None
 1.26A 3lslG-3q3hA:
undetectable		 3lslG-3q3hA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		5 / 12 ASN A 346
GLY A 344
GLN A 367
VAL A 138
THR A 225
 UDP  A 503 (-3.7A)
UDP  A 503 (-3.6A)
None
None
None
 1.40A 3mnoA-5u6sA:
undetectable		 3mnoA-5u6sA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		5 / 12 ASN A 346
GLY A 344
GLN A 367
VAL A 138
THR A 225
 UDP  A 503 (-3.7A)
UDP  A 503 (-3.6A)
None
None
None
 1.38A 3mnpA-5u6sA:
undetectable		 3mnpA-5u6sA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		4 / 6 VAL A  35
VAL A  92
ILE A  74
ARG A  10
 None
None
None
UDP  A1377 (-4.4A)
 1.01A 3ms9A-1f6dA:
undetectable		 3ms9A-1f6dA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		4 / 6 VAL A  35
VAL A  92
ILE A  74
ARG A  10
 None
None
None
UDP  A1377 (-4.4A)
 0.98A 3mssA-1f6dA:
undetectable		 3mssA-1f6dA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Escherichia
coli) 		4 / 6 VAL A  35
VAL A  92
ILE A  74
ARG A  10
 None
None
None
UDP  A1377 (-4.4A)
 0.96A 3mssC-1f6dA:
undetectable		 3mssC-1f6dA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4phs PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)
(Streptococcus
parasanguinis) 		5 / 11 GLN A  57
ASP A 210
ALA A 176
PHE A 177
ILE A 183
 None
None
UDP  A 301 (-3.3A)
None
None
 1.38A 3n23A-4phsA:
undetectable		 3n23A-4phsA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_D_AG2D1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		5 / 10 ASP A  39
SER A  36
GLY A  20
ARG A 131
ASP A 139
 None
MG  A 500 ( 4.5A)
ADP  A 195 (-3.7A)
BF2  A 501 ( 2.6A)
UDP  A 196 ( 4.6A)
 1.25A 3n2oC-4ukdA:
undetectable
3n2oD-4ukdA:
undetectable		 3n2oC-4ukdA:
14.88
3n2oD-4ukdA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 3n2rA-6bk1A:
undetectable
3n2rB-6bk1A:
undetectable		 3n2rA-6bk1A:
13.48
3n2rB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 3n2rA-6bk1A:
undetectable
3n2rB-6bk1A:
undetectable		 3n2rA-6bk1A:
13.48
3n2rB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.34A 3n5vA-6bk1A:
undetectable
3n5vB-6bk1A:
undetectable		 3n5vA-6bk1A:
13.48
3n5vB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3n5yA-6bk1A:
undetectable
3n5yB-6bk1A:
undetectable		 3n5yA-6bk1A:
13.48
3n5yB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3n5zA-6bk1A:
undetectable
3n5zB-6bk1A:
undetectable		 3n5zA-6bk1A:
13.48
3n5zB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3nlkA-6bk1A:
undetectable
3nlkB-6bk1A:
undetectable		 3nlkA-6bk1A:
13.48
3nlkB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3nlkA-6bk1A:
undetectable
3nlkB-6bk1A:
undetectable		 3nlkA-6bk1A:
13.48
3nlkB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3nlmA-6bk1A:
undetectable
3nlmB-6bk1A:
undetectable		 3nlmA-6bk1A:
13.48
3nlmB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3nlnA-6bk1A:
undetectable
3nlnB-6bk1A:
undetectable		 3nlnA-6bk1A:
13.48
3nlnB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.32A 3nloA-6bk1A:
undetectable
3nloB-6bk1A:
undetectable		 3nloA-6bk1A:
13.48
3nloB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 3nloA-6bk1A:
undetectable
3nloB-6bk1A:
undetectable		 3nloA-6bk1A:
13.48
3nloB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3nlpA-6bk1A:
undetectable
3nlpB-6bk1A:
undetectable		 3nlpA-6bk1A:
13.48
3nlpB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3nlvA-6bk1A:
undetectable
3nlvB-6bk1A:
undetectable		 3nlvA-6bk1A:
13.48
3nlvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3nlvA-6bk1A:
0.0
3nlvB-6bk1A:
undetectable		 3nlvA-6bk1A:
13.48
3nlvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3nlwA-6bk1A:
undetectable
3nlwB-6bk1A:
0.1		 3nlwA-6bk1A:
13.48
3nlwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3nlwA-6bk1A:
undetectable
3nlwB-6bk1A:
0.1		 3nlwA-6bk1A:
13.48
3nlwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.25A 3nlxA-6bk1A:
undetectable
3nlxB-6bk1A:
undetectable		 3nlxA-6bk1A:
13.48
3nlxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3nlyA-6bk1A:
undetectable
3nlyB-6bk1A:
undetectable		 3nlyA-6bk1A:
13.48
3nlyB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3nlzA-6bk1A:
undetectable
3nlzB-6bk1A:
undetectable		 3nlzA-6bk1A:
13.48
3nlzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 3nlzA-6bk1A:
undetectable
3nlzB-6bk1A:
undetectable		 3nlzA-6bk1A:
13.48
3nlzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 3nm0A-6bk1A:
undetectable
3nm0B-6bk1A:
undetectable		 3nm0A-6bk1A:
13.48
3nm0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 3nm0A-6bk1A:
undetectable
3nm0B-6bk1A:
undetectable		 3nm0A-6bk1A:
13.48
3nm0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 4x7m TARM
(Staphylococcus
aureus) 		5 / 12 LYS A 331
GLY A 427
SER A 303
ALA A 285
GLN A 286
 UDP  A 500 (-3.0A)
None
None
None
None
 1.36A 3nmuA-4x7mA:
undetectable
3nmuF-4x7mA:
3.9		 3nmuA-4x7mA:
22.33
3nmuF-4x7mA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 3nnyA-6bk1A:
undetectable
3nnyB-6bk1A:
0.0		 3nnyA-6bk1A:
13.48
3nnyB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 3nnzA-6bk1A:
undetectable
3nnzB-6bk1A:
undetectable		 3nnzA-6bk1A:
13.48
3nnzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3nnzA-6bk1A:
undetectable
3nnzB-6bk1A:
undetectable		 3nnzA-6bk1A:
13.48
3nnzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 GLU A 292
LEU A 182
LEU A  25
 UDP  A1081 (-2.7A)
None
None
 0.76A 3ohtA-3beoA:
undetectable		 3ohtA-3beoA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3pneA-6bk1A:
undetectable
3pneB-6bk1A:
undetectable		 3pneA-6bk1A:
13.48
3pneB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3pnfA-6bk1A:
undetectable
3pnfB-6bk1A:
undetectable		 3pnfA-6bk1A:
13.48
3pnfB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.25A 3pngA-6bk1A:
undetectable
3pngB-6bk1A:
undetectable		 3pngA-6bk1A:
13.48
3pngB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3q99A-6bk1A:
undetectable
3q99B-6bk1A:
undetectable		 3q99A-6bk1A:
13.48
3q99B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3q99A-6bk1A:
undetectable
3q99B-6bk1A:
undetectable		 3q99A-6bk1A:
13.48
3q99B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3q9aA-6bk1A:
undetectable
3q9aB-6bk1A:
undetectable		 3q9aA-6bk1A:
13.48
3q9aB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 3q9aA-6bk1A:
undetectable
3q9aB-6bk1A:
undetectable		 3q9aA-6bk1A:
13.48
3q9aB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 7 GLN A 310
GLU A 155
ARG A 315
PRO A 350
 UDP  A 402 (-4.0A)
None
None
None
 1.40A 3ql6A-5xvsA:
undetectable		 3ql6A-5xvsA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		3 / 3 LEU A 259
ARG A 293
ASN A  27
 None
None
UDP  A1424 (-4.0A)
 0.71A 3qxvD-2iyaA:
undetectable		 3qxvD-2iyaA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 3rqjA-6bk1A:
undetectable
3rqjB-6bk1A:
undetectable		 3rqjA-6bk1A:
13.48
3rqjB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 3rqjA-6bk1A:
undetectable
3rqjB-6bk1A:
undetectable		 3rqjA-6bk1A:
13.48
3rqjB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 3rqkA-6bk1A:
0.0
3rqkB-6bk1A:
0.0		 3rqkA-6bk1A:
13.48
3rqkB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3rqkA-6bk1A:
undetectable
3rqkB-6bk1A:
0.0		 3rqkA-6bk1A:
13.48
3rqkB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3rqlA-6bk1A:
undetectable
3rqlB-6bk1A:
undetectable		 3rqlA-6bk1A:
13.48
3rqlB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3rqlA-6bk1A:
undetectable
3rqlB-6bk1A:
undetectable		 3rqlA-6bk1A:
13.48
3rqlB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3rqmA-6bk1A:
undetectable
3rqmB-6bk1A:
undetectable		 3rqmA-6bk1A:
13.48
3rqmB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3rqnA-6bk1A:
undetectable
3rqnB-6bk1A:
undetectable		 3rqnA-6bk1A:
13.48
3rqnB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		3 / 3 HIS A 180
SER A 294
GLU A 295
 None
None
UDP  A 402 (-3.1A)
 0.76A 3s8pA-5xvsA:
undetectable		 3s8pA-5xvsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 12 GLN A 292
GLY A 289
ASP A  95
ILE A 149
ALA A 150
 None
UDP  A 401 (-3.7A)
UD1  A 400 ( 4.8A)
None
None
 0.92A 3sudC-4nesA:
undetectable		 3sudC-4nesA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.01A 3sudD-3s29A:
undetectable		 3sudD-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 0.99A 3sueA-3s29A:
undetectable		 3sueA-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.02A 3sueB-3s29A:
undetectable		 3sueB-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.03A 3sueC-3s29A:
undetectable		 3sueC-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 0.92A 3sufB-3s29A:
undetectable		 3sufB-3s29A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.25A 3svpA-6bk1A:
undetectable
3svpB-6bk1A:
undetectable		 3svpA-6bk1A:
13.48
3svpB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 3svqA-6bk1A:
0.0
3svqB-6bk1A:
undetectable		 3svqA-6bk1A:
13.48
3svqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3svqA-6bk1A:
0.0
3svqB-6bk1A:
undetectable		 3svqA-6bk1A:
13.48
3svqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3tylA-6bk1A:
undetectable
3tylB-6bk1A:
undetectable		 3tylA-6bk1A:
13.48
3tylB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 3tylA-6bk1A:
undetectable
3tylB-6bk1A:
undetectable		 3tylA-6bk1A:
13.48
3tylB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 3tymA-6bk1A:
undetectable
3tymB-6bk1A:
undetectable		 3tymA-6bk1A:
13.48
3tymB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3tymA-6bk1A:
undetectable
3tymB-6bk1A:
undetectable		 3tymA-6bk1A:
13.48
3tymB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3tynA-6bk1A:
undetectable
3tynB-6bk1A:
undetectable		 3tynA-6bk1A:
13.48
3tynB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3tynA-6bk1A:
undetectable
3tynB-6bk1A:
undetectable		 3tynA-6bk1A:
13.48
3tynB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 3tyoA-6bk1A:
undetectable
3tyoB-6bk1A:
undetectable		 3tyoA-6bk1A:
13.48
3tyoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 3tyoA-6bk1A:
undetectable
3tyoB-6bk1A:
undetectable		 3tyoA-6bk1A:
13.48
3tyoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 12 ILE A 294
GLY A 292
GLY A 293
THR A 212
LEU A 210
 None
UDP  A 501 (-3.7A)
UDP  A 501 (-3.7A)
UDP  A 501 (-4.7A)
None
 1.02A 3uboB-5dldA:
6.1		 3uboB-5dldA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 3ufqA-6bk1A:
undetectable
3ufqB-6bk1A:
0.0		 3ufqA-6bk1A:
13.48
3ufqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 3ufqA-6bk1A:
undetectable
3ufqB-6bk1A:
undetectable		 3ufqA-6bk1A:
13.48
3ufqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.25A 3uftA-6bk1A:
undetectable
3uftB-6bk1A:
undetectable		 3uftA-6bk1A:
13.48
3uftB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 3ufuA-6bk1A:
undetectable
3ufuB-6bk1A:
undetectable		 3ufuA-6bk1A:
13.48
3ufuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3ufuA-6bk1A:
undetectable
3ufuB-6bk1A:
undetectable		 3ufuA-6bk1A:
13.48
3ufuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 3ufvA-6bk1A:
undetectable
3ufvB-6bk1A:
undetectable		 3ufvA-6bk1A:
13.48
3ufvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3ufvA-6bk1A:
undetectable
3ufvB-6bk1A:
undetectable		 3ufvA-6bk1A:
13.48
3ufvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 3ufwA-6bk1A:
0.0
3ufwB-6bk1A:
undetectable		 3ufwA-6bk1A:
13.48
3ufwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3ckn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 8 VAL A 278
TYR A 234
LEU A 123
TYR A 218
 None
UDP  A 332 (-4.7A)
None
None
 0.89A 3v81A-3cknA:
undetectable		 3v81A-3cknA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 5v4a GLYCOSYLTRANSFERASE
(DUF1792)
(Streptococcus
sanguinis) 		4 / 6 HIS A 223
GLU A 147
ASP A 260
ASN A 157
 UDP  A 301 (-3.5A)
None
None
None
 1.30A 3vywA-5v4aA:
undetectable		 3vywA-5v4aA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 4dsh UDP-GALACTOPYRANOSE
MUTASE
(Trypanosoma
cruzi) 		4 / 6 ARG A 176
ASP A 435
ASN A 433
TYR A 429
 UDP  A 501 (-4.1A)
None
FDA  A 502 (-4.3A)
UDP  A 501 (-4.4A)
 1.23A 3wfaA-4dshA:
undetectable
3wfaB-4dshA:
undetectable		 3wfaA-4dshA:
20.69
3wfaB-4dshA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE
(Homo
sapiens) 		4 / 6 ILE A 316
LEU A 332
ARG A 321
THR A 320
 None
None
UDP  A 501 (-3.1A)
None
 1.06A 3wg7A-4zhtA:
undetectable
3wg7J-4zhtA:
undetectable		 3wg7A-4zhtA:
20.56
3wg7J-4zhtA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4dsh UDP-GALACTOPYRANOSE
MUTASE
(Trypanosoma
cruzi) 		3 / 3 ASN A 465
GLU A 175
ARG A 176
 None
None
UDP  A 501 (-4.1A)
 0.99A 3wxoA-4dshA:
undetectable		 3wxoA-4dshA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		3 / 3 ASN A  56
GLU A  54
ARG A  55
 None
UDP  A 501 (-4.9A)
None
 1.06A 3wxoA-6dusA:
undetectable		 3wxoA-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		5 / 12 PRO A 224
LEU A 231
LEU A 328
TYR A 241
TYR A 268
 None
None
None
UDP  A 503 (-4.3A)
None
 1.38A 4a79A-5u6sA:
undetectable		 4a79A-5u6sA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 PRO A  20
VAL A 274
ALA A 346
SER A 348
MET A 350
 None
UDP  A1001 ( 4.3A)
GOL  A1002 ( 3.4A)
UDP  A1001 (-2.5A)
None
 1.45A 4a84A-4whmA:
undetectable		 4a84A-4whmA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4x7m TARM
(Staphylococcus
aureus) 		4 / 8 ILE A 414
PHE A 431
GLN A 405
GLY A 406
 None
None
None
UDP  A 500 ( 3.8A)
 0.83A 4acbC-4x7mA:
6.9		 4acbC-4x7mA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5tzk GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 6 SER C  92
ASP C  94
THR C  17
ILE C  16
 UDP  C 401 (-2.8A)
MN  C 402 ( 4.0A)
None
None
 0.98A 4acbC-5tzkC:
3.1		 4acbC-5tzkC:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4c39A-6bk1A:
0.0
4c39B-6bk1A:
undetectable		 4c39A-6bk1A:
13.48
4c39B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4c39A-6bk1A:
0.0
4c39B-6bk1A:
undetectable		 4c39A-6bk1A:
13.48
4c39B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.25A 4camA-6bk1A:
undetectable
4camB-6bk1A:
undetectable		 4camA-6bk1A:
13.48
4camB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 4canA-6bk1A:
undetectable
4canB-6bk1A:
undetectable		 4canA-6bk1A:
13.48
4canB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4caoA-6bk1A:
undetectable
4caoB-6bk1A:
undetectable		 4caoA-6bk1A:
13.48
4caoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4capA-6bk1A:
undetectable
4capB-6bk1A:
undetectable		 4capA-6bk1A:
13.48
4capB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4caqA-6bk1A:
undetectable
4caqB-6bk1A:
undetectable		 4caqA-6bk1A:
13.48
4caqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4ctpA-6bk1A:
undetectable
4ctpB-6bk1A:
undetectable		 4ctpA-6bk1A:
13.48
4ctpB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4ctqA-6bk1A:
0.0
4ctqB-6bk1A:
undetectable		 4ctqA-6bk1A:
13.48
4ctqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4ctrA-6bk1A:
0.0
4ctrB-6bk1A:
undetectable		 4ctrA-6bk1A:
13.48
4ctrB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 4cttA-6bk1A:
undetectable
4cttB-6bk1A:
undetectable		 4cttA-6bk1A:
13.48
4cttB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4cttA-6bk1A:
undetectable
4cttB-6bk1A:
undetectable		 4cttA-6bk1A:
13.48
4cttB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4ctuA-6bk1A:
undetectable
4ctuB-6bk1A:
undetectable		 4ctuA-6bk1A:
13.48
4ctuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4ctuA-6bk1A:
undetectable
4ctuB-6bk1A:
undetectable		 4ctuA-6bk1A:
13.48
4ctuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 4ctwA-6bk1A:
0.0
4ctwB-6bk1A:
undetectable		 4ctwA-6bk1A:
13.48
4ctwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4cx3A-6bk1A:
0.0
4cx3B-6bk1A:
undetectable		 4cx3A-6bk1A:
13.48
4cx3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4cx3A-6bk1A:
0.0
4cx3B-6bk1A:
undetectable		 4cx3A-6bk1A:
13.48
4cx3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4cx4A-6bk1A:
0.0
4cx4B-6bk1A:
undetectable		 4cx4A-6bk1A:
13.48
4cx4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4cx5A-6bk1A:
undetectable
4cx5B-6bk1A:
undetectable		 4cx5A-6bk1A:
13.48
4cx5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4cx5A-6bk1A:
undetectable
4cx5B-6bk1A:
undetectable		 4cx5A-6bk1A:
13.48
4cx5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4cx6A-6bk1A:
undetectable
4cx6B-6bk1A:
undetectable		 4cx6A-6bk1A:
13.48
4cx6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 PHE E  73
ARG E  72
ILE E  80
TRP E  65
 None
None
None
UDP  E 403 (-4.0A)
 1.46A 4cx7C-5xykE:
undetectable
4cx7D-5xykE:
undetectable		 4cx7C-5xykE:
11.53
4cx7D-5xykE:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 4d1nA-6bk1A:
undetectable
4d1nB-6bk1A:
undetectable		 4d1nA-6bk1A:
13.48
4d1nB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 4d1nA-6bk1A:
undetectable
4d1nB-6bk1A:
undetectable		 4d1nA-6bk1A:
13.48
4d1nB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4d1nC-6bk1A:
undetectable
4d1nD-6bk1A:
undetectable		 4d1nC-6bk1A:
13.48
4d1nD-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 4d1nC-6bk1A:
undetectable
4d1nD-6bk1A:
undetectable		 4d1nC-6bk1A:
13.48
4d1nD-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4d2yA-6bk1A:
undetectable
4d2yB-6bk1A:
undetectable		 4d2yA-6bk1A:
13.48
4d2yB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4d2yA-6bk1A:
undetectable
4d2yB-6bk1A:
undetectable		 4d2yA-6bk1A:
13.48
4d2yB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 4d2zA-6bk1A:
undetectable
4d2zB-6bk1A:
undetectable		 4d2zA-6bk1A:
13.48
4d2zB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4d30A-6bk1A:
undetectable
4d30B-6bk1A:
0.0		 4d30A-6bk1A:
13.48
4d30B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 4d30A-6bk1A:
undetectable
4d30B-6bk1A:
0.0		 4d30A-6bk1A:
13.48
4d30B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 4d31A-6bk1A:
undetectable
4d31B-6bk1A:
undetectable		 4d31A-6bk1A:
13.48
4d31B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.32A 4d31A-6bk1A:
undetectable
4d31B-6bk1A:
undetectable		 4d31A-6bk1A:
13.48
4d31B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.24A 4d32A-6bk1A:
undetectable
4d32B-6bk1A:
undetectable		 4d32A-6bk1A:
13.48
4d32B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 4d32A-6bk1A:
undetectable
4d32B-6bk1A:
undetectable		 4d32A-6bk1A:
13.48
4d32B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 4d3bA-6bk1A:
undetectable
4d3bB-6bk1A:
undetectable		 4d3bA-6bk1A:
13.48
4d3bB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4d3bA-6bk1A:
undetectable
4d3bB-6bk1A:
undetectable		 4d3bA-6bk1A:
13.48
4d3bB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4d7oA-6bk1A:
undetectable
4d7oB-6bk1A:
undetectable		 4d7oA-6bk1A:
13.48
4d7oB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4d7oA-6bk1A:
undetectable
4d7oB-6bk1A:
undetectable		 4d7oA-6bk1A:
13.48
4d7oB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		4 / 5 LEU A  50
ILE A  17
ALA A  52
PHE A  53
 None
UDP  A 402 (-3.7A)
None
None
 1.04A 4dc3B-4fkzA:
9.3		 4dc3B-4fkzA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Pyrococcus
abyssi) 		3 / 3 TYR A  79
THR A 136
GLU A 100
 None
UDP  A 250 (-2.8A)
None
 0.70A 4df3A-2pnzA:
undetectable		 4df3A-2pnzA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2pnz PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Pyrococcus
abyssi) 		3 / 3 TYR A  79
THR A 136
GLU A 100
 None
UDP  A 250 (-2.8A)
None
 0.70A 4df3B-2pnzA:
undetectable		 4df3B-2pnzA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 2wzf GLUCOSYLTRANSFERASE
(Legionella
pneumophila) 		4 / 6 LEU A 196
LEU A 170
ILE A 247
MET A 148
 None
None
UDP  A1525 (-4.6A)
None
 0.95A 4do3B-2wzfA:
undetectable		 4do3B-2wzfA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1105_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2ffu POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 2
(Homo
sapiens) 		5 / 11 PHE A 144
GLY A  88
ASP A 110
ARG A 101
ARG A 362
 None
None
None
None
UDP  A 601 (-4.1A)
 1.38A 4dx7A-2ffuA:
0.0		 4dx7A-2ffuA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		4 / 8 GLN A 315
PHE A 221
ILE A 403
VAL A 399
 UDP  A1424 (-3.4A)
None
None
None
 0.77A 4dx7B-2iyaA:
undetectable		 4dx7B-2iyaA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		5 / 12 GLY A 307
ALA A 308
SER A 311
GLY A 314
LEU A 315
 UDP  A1401 ( 3.9A)
UDP  A1401 (-4.3A)
None
None
None
 0.47A 4e1gA-2iyfA:
undetectable		 4e1gA-2iyfA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		5 / 12 GLY A 307
ALA A 308
SER A 311
GLY A 314
LEU A 315
 UDP  A1401 ( 3.9A)
UDP  A1401 (-4.3A)
None
None
None
 0.49A 4e1gB-2iyfA:
undetectable		 4e1gB-2iyfA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 5f84 COAGULATION FACTOR
IX
O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster;
Homo
sapiens) 		4 / 7 ASN B  54
GLY A 190
THR A 185
PHE A 278
 None
None
None
UDP  A 501 ( 3.3A)
 0.91A 4ejjB-5f84B:
undetectable		 4ejjB-5f84B:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 6 ARG A 191
ILE A 189
VAL A 272
LEU A 262
 UDP  A 401 (-3.5A)
None
UDP  A 401 (-4.3A)
None
 1.10A 4em2A-6ejjA:
undetectable		 4em2A-6ejjA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4euxA-6bk1A:
undetectable
4euxB-6bk1A:
undetectable		 4euxA-6bk1A:
13.48
4euxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 4euxA-6bk1A:
undetectable
4euxB-6bk1A:
undetectable		 4euxA-6bk1A:
13.48
4euxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2d7i POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 10
(Homo
sapiens) 		5 / 12 GLY A 112
TYR A 375
GLU A 156
ILE A 371
ILE A 115
 None
None
UDP  A 705 (-3.6A)
None
None
 1.18A 4fglA-2d7iA:
undetectable
4fglB-2d7iA:
undetectable		 4fglA-2d7iA:
16.19
4fglB-2d7iA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 139
ILE A 239
LEU A 409
ASP A 376
GLY A 377
 None
None
None
UDP  A 501 ( 4.5A)
None
 1.13A 4fogA-5v0tA:
undetectable		 4fogA-5v0tA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 1gz5 ALPHA-TREHALOSE-PHOS
PHATE SYNTHASE
(Escherichia
coli) 		5 / 11 HIS A 129
ILE A 225
LEU A 394
ASP A 361
GLY A 362
 None
IMD  A 902 ( 4.3A)
None
UDP  A 900 ( 4.5A)
None
 1.04A 4fogC-1gz5A:
0.0		 4fogC-1gz5A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 139
ILE A 239
LEU A 409
ASP A 376
GLY A 377
 None
None
None
UDP  A 501 ( 4.5A)
None
 0.99A 4fogC-5v0tA:
undetectable		 4fogC-5v0tA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 475
PHE A 296
TYR A 492
VAL A 356
ALA A 318
 None
None
UDP  A 801 (-3.2A)
None
UDP  A 801 ( 4.3A)
 1.14A 4foxD-5vncA:
undetectable		 4foxD-5vncA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 475
PHE A 296
TYR A 492
VAL A 356
ALA A 318
 None
None
UDP  A 801 (-3.2A)
None
UDP  A 801 ( 4.3A)
 1.14A 4fqsA-5vncA:
undetectable		 4fqsA-5vncA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 475
PHE A 296
TYR A 492
VAL A 356
ALA A 318
 None
None
UDP  A 801 (-3.2A)
None
UDP  A 801 ( 4.3A)
 1.15A 4fqsB-5vncA:
undetectable		 4fqsB-5vncA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 4fvwA-6bk1A:
undetectable
4fvwB-6bk1A:
undetectable		 4fvwA-6bk1A:
13.48
4fvwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4fvyA-6bk1A:
undetectable
4fvyB-6bk1A:
undetectable		 4fvyA-6bk1A:
13.48
4fvyB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 4fvyA-6bk1A:
undetectable
4fvyB-6bk1A:
undetectable		 4fvyA-6bk1A:
13.48
4fvyB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 4fvzA-6bk1A:
undetectable
4fvzB-6bk1A:
undetectable		 4fvzA-6bk1A:
13.48
4fvzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 4fvzA-6bk1A:
undetectable
4fvzB-6bk1A:
undetectable		 4fvzA-6bk1A:
13.48
4fvzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 4fw0A-6bk1A:
undetectable
4fw0B-6bk1A:
undetectable		 4fw0A-6bk1A:
13.48
4fw0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 4fw0A-6bk1A:
undetectable
4fw0B-6bk1A:
undetectable		 4fw0A-6bk1A:
13.48
4fw0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 4pqg GLYCOSYLTRANSFERASE
GTF1
(Streptococcus
pneumoniae) 		4 / 7 ARG A 328
GLY A  16
ASN A   7
GLU A  18
 UDP  A 601 (-3.8A)
UDP  A 601 ( 3.0A)
None
None
 1.09A 4g0vA-4pqgA:
2.6		 4g0vA-4pqgA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5e9u GLYCOSYLTRANSFERASE
GTF1
(Streptococcus
gordonii) 		4 / 7 ARG A 328
GLY A  16
ASN A   7
GLU A  18
 None
UDP  A 601 (-3.1A)
None
None
 0.90A 4g0vA-5e9uA:
undetectable		 4g0vA-5e9uA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 4pqg GLYCOSYLTRANSFERASE
GTF1
(Streptococcus
pneumoniae) 		4 / 6 ARG A 328
GLY A  16
ASN A   7
GLU A  18
 UDP  A 601 (-3.8A)
UDP  A 601 ( 3.0A)
None
None
 1.20A 4g0vB-4pqgA:
3.2		 4g0vB-4pqgA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 5e9u GLYCOSYLTRANSFERASE
GTF1
(Streptococcus
gordonii) 		4 / 6 ARG A 328
GLY A  16
ASN A   7
GLU A  18
 None
UDP  A 601 (-3.1A)
None
None
 0.87A 4g0vB-5e9uA:
2.6		 4g0vB-5e9uA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 LYS A 259
ILE A 143
THR A 267
 None
None
UDP  A 353 ( 4.6A)
 0.81A 4gh8A-1jiuA:
2.0		 4gh8A-1jiuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4gqeA-6bk1A:
undetectable
4gqeB-6bk1A:
0.0		 4gqeA-6bk1A:
13.48
4gqeB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 8 ILE A 256
ILE A 210
PHE A 212
GLY A 214
 None
None
None
UDP  A 353 (-3.2A)
 0.90A 4hb6A-1jiuA:
undetectable		 4hb6A-1jiuA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 8 ILE A 256
ILE A 210
PHE A 212
GLY A 214
 None
None
None
UDP  A 353 (-3.2A)
 0.80A 4hb8A-1jiuA:
undetectable		 4hb8A-1jiuA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 8 ILE A 256
ILE A 210
PHE A 212
GLY A 214
 None
None
None
UDP  A 353 (-3.2A)
 0.96A 4hdlA-1jiuA:
undetectable		 4hdlA-1jiuA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 12 ILE A 261
ALA A 322
GLU A 316
ALA A 334
VAL A 332
 None
None
UDP  A 600 (-3.2A)
None
None
 1.09A 4hfpD-3c4qA:
undetectable		 4hfpD-3c4qA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3rmv GLYCOGENIN-1
(Homo
sapiens) 		4 / 4 LEU A  92
LEU A   9
GLN A   4
GLU A 119
 None
UDP  A 264 (-4.1A)
None
None
 1.24A 4i41A-3rmvA:
undetectable		 4i41A-3rmvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4imtA-6bk1A:
0.0
4imtB-6bk1A:
undetectable		 4imtA-6bk1A:
13.48
4imtB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4imtA-6bk1A:
0.0
4imtB-6bk1A:
undetectable		 4imtA-6bk1A:
13.48
4imtB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 4imwA-6bk1A:
undetectable
4imwB-6bk1A:
undetectable		 4imwA-6bk1A:
13.48
4imwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 4jsfA-6bk1A:
undetectable
4jsfB-6bk1A:
undetectable		 4jsfA-6bk1A:
13.48
4jsfB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.25A 4jsfA-6bk1A:
undetectable
4jsfB-6bk1A:
undetectable		 4jsfA-6bk1A:
13.48
4jsfB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4jsgA-6bk1A:
undetectable
4jsgB-6bk1A:
undetectable		 4jsgA-6bk1A:
13.48
4jsgB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 4jsgA-6bk1A:
undetectable
4jsgB-6bk1A:
undetectable		 4jsgA-6bk1A:
13.48
4jsgB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 4jshA-6bk1A:
undetectable
4jshB-6bk1A:
undetectable		 4jshA-6bk1A:
13.48
4jshB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4jsiA-6bk1A:
undetectable
4jsiB-6bk1A:
0.1		 4jsiA-6bk1A:
13.48
4jsiB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4jsjA-6bk1A:
undetectable
4jsjB-6bk1A:
undetectable		 4jsjA-6bk1A:
13.48
4jsjB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 4jsjA-6bk1A:
undetectable
4jsjB-6bk1A:
undetectable		 4jsjA-6bk1A:
13.48
4jsjB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4k5dA-6bk1A:
undetectable
4k5dB-6bk1A:
undetectable		 4k5dA-6bk1A:
13.48
4k5dB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4k5eA-6bk1A:
undetectable
4k5eB-6bk1A:
0.0		 4k5eA-6bk1A:
13.48
4k5eB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4k5eA-6bk1A:
undetectable
4k5eB-6bk1A:
0.0		 4k5eA-6bk1A:
13.48
4k5eB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4k5fA-6bk1A:
undetectable
4k5fB-6bk1A:
undetectable		 4k5fA-6bk1A:
13.48
4k5fB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4k5gA-6bk1A:
undetectable
4k5gB-6bk1A:
undetectable		 4k5gA-6bk1A:
13.48
4k5gB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4k5gA-6bk1A:
undetectable
4k5gB-6bk1A:
undetectable		 4k5gA-6bk1A:
13.48
4k5gB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 4kchA-6bk1A:
undetectable
4kchB-6bk1A:
undetectable		 4kchA-6bk1A:
13.48
4kchB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4kciA-6bk1A:
undetectable
4kciB-6bk1A:
undetectable		 4kciA-6bk1A:
13.48
4kciB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4kcjA-6bk1A:
undetectable
4kcjB-6bk1A:
undetectable		 4kcjA-6bk1A:
13.48
4kcjB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4kcjA-6bk1A:
undetectable
4kcjB-6bk1A:
undetectable		 4kcjA-6bk1A:
13.48
4kcjB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.25A 4kckA-6bk1A:
0.0
4kckB-6bk1A:
undetectable		 4kckA-6bk1A:
13.48
4kckB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 4kckA-6bk1A:
0.0
4kckB-6bk1A:
undetectable		 4kckA-6bk1A:
13.48
4kckB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 4kclA-6bk1A:
undetectable
4kclB-6bk1A:
undetectable		 4kclA-6bk1A:
13.48
4kclB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4kcmA-6bk1A:
undetectable
4kcmB-6bk1A:
undetectable		 4kcmA-6bk1A:
13.48
4kcmB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 4kcmA-6bk1A:
undetectable
4kcmB-6bk1A:
undetectable		 4kcmA-6bk1A:
13.48
4kcmB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4kcoA-6bk1A:
undetectable
4kcoB-6bk1A:
undetectable		 4kcoA-6bk1A:
13.48
4kcoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		4 / 8 LEU A 179
SER A  17
VAL A 269
GLY A 270
 None
None
UDP  A 401 (-3.8A)
UDP  A 401 ( 4.7A)
 0.82A 4klrB-4nesA:
2.8		 4klrB-4nesA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		4 / 8 ARG A 131
ARG A 148
ASP A  89
ARG A  93
 BF2  A 501 ( 2.6A)
BF2  A 501 ( 3.6A)
MG  A 500 ( 4.1A)
UDP  A 196 (-2.9A)
 1.34A 4kr4C-4ukdA:
undetectable		 4kr4C-4ukdA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5tzk GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		5 / 10 VAL C   5
ALA C  78
SER C  92
LEU C  20
VAL C  35
 None
None
UDP  C 401 (-2.8A)
None
None
 1.42A 4kyaC-5tzkC:
undetectable		 4kyaC-5tzkC:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5tzk GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		5 / 11 VAL C   5
ALA C  78
SER C  92
LEU C  20
VAL C  35
 None
None
UDP  C 401 (-2.8A)
None
None
 1.43A 4kyaE-5tzkC:
undetectable		 4kyaE-5tzkC:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5tzk GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		5 / 11 VAL C   5
ALA C  78
SER C  92
LEU C  20
VAL C  35
 None
None
UDP  C 401 (-2.8A)
None
None
 1.41A 4kyaG-5tzkC:
2.7		 4kyaG-5tzkC:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 4luxA-6bk1A:
0.0
4luxB-6bk1A:
undetectable		 4luxA-6bk1A:
13.48
4luxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4luxA-6bk1A:
undetectable
4luxB-6bk1A:
undetectable		 4luxA-6bk1A:
13.48
4luxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2
(Arabidopsis
thaliana) 		4 / 5 GLN A  24
THR A  20
LEU A 331
LEU A 328
 None
UDP  A 503 ( 4.3A)
None
None
 0.92A 4lvcB-5u6sA:
4.9		 4lvcB-5u6sA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 4irq BETA-1,4-GALACTOSYLT
RANSFERASE 7
(Homo
sapiens) 		5 / 12 HIS A 195
HIS A 257
ASP A 163
GLY A 202
TYR A 199
 None
MN  A 401 ( 3.5A)
UDP  A 402 (-3.3A)
None
TRS  A 403 (-4.9A)
 1.12A 4lxzA-4irqA:
undetectable		 4lxzA-4irqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 4irq BETA-1,4-GALACTOSYLT
RANSFERASE 7
(Homo
sapiens) 		5 / 11 HIS A 195
HIS A 257
ASP A 163
GLY A 202
TYR A 199
 None
MN  A 401 ( 3.5A)
UDP  A 402 (-3.3A)
None
TRS  A 403 (-4.9A)
 1.12A 4lxzB-4irqA:
undetectable		 4lxzB-4irqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 1fgg GLUCURONYLTRANSFERAS
E I
(Homo
sapiens) 		3 / 3 ARG A 310
GLU A  92
ARG A 156
 UDP  A 337 (-3.6A)
None
UDP  A 337 (-3.1A)
 0.95A 4mwvA-1fggA:
undetectable		 4mwvA-1fggA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 PHE E  73
ARG E  72
ILE E  80
TRP E  65
 None
None
None
UDP  E 403 (-4.0A)
 1.49A 4nosA-5xykE:
undetectable
4nosB-5xykE:
undetectable		 4nosA-5xykE:
11.62
4nosB-5xykE:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		4 / 7 ASP A 376
ARG A 277
SER A 281
HIS A  99
 UDP  A 501 ( 4.5A)
UDP  A 501 ( 3.9A)
None
None
 1.46A 4o4dA-5v0tA:
undetectable		 4o4dA-5v0tA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5l0v PROTEIN
O-GLUCOSYLTRANSFERAS
E 1
(Homo
sapiens) 		3 / 3 PRO A 171
LEU A 181
HIS A 262
 UDP  A1005 ( 4.8A)
UDP  A1005 (-4.8A)
None
 0.71A 4pevA-5l0vA:
3.9		 4pevA-5l0vA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		5 / 12 VAL A  65
SER A  36
GLY A  38
ASP A  89
LYS A  19
 UDP  A 196 (-3.7A)
MG  A 500 ( 4.5A)
UDP  A 196 (-3.6A)
MG  A 500 ( 4.1A)
ADP  A 195 ( 2.7A)
 1.49A 4pevC-4ukdA:
undetectable		 4pevC-4ukdA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3ckn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 8 VAL A 278
TYR A 234
LEU A 123
TYR A 218
 None
UDP  A 332 (-4.7A)
None
None
 0.84A 4puoC-3cknA:
undetectable		 4puoC-3cknA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_1
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 5ndf POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 367
HIS A 365
ASP A 224
TYR A 324
 UDP  A 602 (-3.7A)
None
UDP  A 602 ( 3.2A)
None
 1.49A 4qdjA-5ndfA:
undetectable		 4qdjA-5ndfA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		4 / 7 GLU A 313
THR A 317
GLY A 314
THR A 319
 UDP  A1401 (-2.7A)
None
None
None
 0.93A 4qwpB-2iyfA:
undetectable		 4qwpB-2iyfA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		4 / 6 ALA A 274
ILE A 177
SER A 284
ILE A 280
 None
None
UDP  A 402 (-2.7A)
None
 0.77A 4r21A-4fkzA:
undetectable		 4r21A-4fkzA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		3 / 3 GLU A 128
ARG A 139
GLN A 310
 None
None
UDP  A 402 (-4.0A)
 0.94A 4rtbA-5xvsA:
undetectable		 4rtbA-5xvsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 12 ASN A 346
GLY A 290
ALA A 319
VAL A 317
GLN A 292
 None
UDP  A 401 (-3.6A)
None
None
None
 1.22A 4ryaA-4nesA:
1.2		 4ryaA-4nesA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		4 / 5 ILE A 342
PRO A 341
HIS A 356
VAL A 321
 None
None
None
UDP  A 600 ( 3.9A)
 1.04A 4s0vA-3c4qA:
22.9		 4s0vA-3c4qA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 4uchA-6bk1A:
undetectable
4uchB-6bk1A:
undetectable		 4uchA-6bk1A:
13.48
4uchB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 4uchA-6bk1A:
undetectable
4uchB-6bk1A:
undetectable		 4uchA-6bk1A:
13.48
4uchB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4ugzA-6bk1A:
undetectable
4ugzB-6bk1A:
undetectable		 4ugzA-6bk1A:
13.48
4ugzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 4ugzA-6bk1A:
undetectable
4ugzB-6bk1A:
undetectable		 4ugzA-6bk1A:
13.48
4ugzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4uh0A-6bk1A:
undetectable
4uh0B-6bk1A:
undetectable		 4uh0A-6bk1A:
13.48
4uh0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4uh1A-6bk1A:
undetectable
4uh1B-6bk1A:
undetectable		 4uh1A-6bk1A:
13.48
4uh1B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4uh1A-6bk1A:
undetectable
4uh1B-6bk1A:
undetectable		 4uh1A-6bk1A:
13.48
4uh1B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4uh2A-6bk1A:
undetectable
4uh2B-6bk1A:
undetectable		 4uh2A-6bk1A:
13.48
4uh2B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 4uh2A-6bk1A:
undetectable
4uh2B-6bk1A:
undetectable		 4uh2A-6bk1A:
13.48
4uh2B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4uh3A-6bk1A:
0.1
4uh3B-6bk1A:
0.0		 4uh3A-6bk1A:
13.48
4uh3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4uh3A-6bk1A:
0.1
4uh3B-6bk1A:
undetectable		 4uh3A-6bk1A:
13.48
4uh3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4uh4A-6bk1A:
undetectable
4uh4B-6bk1A:
undetectable		 4uh4A-6bk1A:
13.48
4uh4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4uh4A-6bk1A:
undetectable
4uh4B-6bk1A:
undetectable		 4uh4A-6bk1A:
13.48
4uh4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4uh5A-6bk1A:
undetectable
4uh5B-6bk1A:
undetectable		 4uh5A-6bk1A:
13.48
4uh5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 4uh5A-6bk1A:
undetectable
4uh5B-6bk1A:
undetectable		 4uh5A-6bk1A:
13.48
4uh5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4uh6A-6bk1A:
undetectable
4uh6B-6bk1A:
undetectable		 4uh6A-6bk1A:
13.48
4uh6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4uh6A-6bk1A:
undetectable
4uh6B-6bk1A:
undetectable		 4uh6A-6bk1A:
13.48
4uh6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE
(Homo
sapiens) 		5 / 12 HIS A 110
SER A  23
GLU A 134
GLY A 182
PRO A 184
 None
UDP  A 501 (-2.8A)
None
None
None
 1.28A 4uilH-4zhtA:
undetectable
4uilL-4zhtA:
undetectable		 4uilH-4zhtA:
20.89
4uilL-4zhtA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4upmA-6bk1A:
undetectable
4upmB-6bk1A:
undetectable		 4upmA-6bk1A:
13.48
4upmB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 4upnA-6bk1A:
undetectable
4upnB-6bk1A:
undetectable		 4upnA-6bk1A:
13.48
4upnB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4upnA-6bk1A:
undetectable
4upnB-6bk1A:
undetectable		 4upnA-6bk1A:
13.48
4upnB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4upoA-6bk1A:
undetectable
4upoB-6bk1A:
undetectable		 4upoA-6bk1A:
13.48
4upoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4upoA-6bk1A:
undetectable
4upoB-6bk1A:
undetectable		 4upoA-6bk1A:
13.48
4upoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 4uppA-6bk1A:
undetectable
4uppB-6bk1A:
undetectable		 4uppA-6bk1A:
13.48
4uppB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4uppA-6bk1A:
undetectable
4uppB-6bk1A:
undetectable		 4uppA-6bk1A:
13.48
4uppB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 4v3uA-6bk1A:
0.0
4v3uB-6bk1A:
undetectable		 4v3uA-6bk1A:
13.48
4v3uB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 4v3uA-6bk1A:
0.0
4v3uB-6bk1A:
undetectable		 4v3uA-6bk1A:
13.48
4v3uB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4v3uC-6bk1A:
undetectable
4v3uD-6bk1A:
undetectable		 4v3uC-6bk1A:
13.48
4v3uD-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 4v3uC-6bk1A:
undetectable
4v3uD-6bk1A:
undetectable		 4v3uC-6bk1A:
13.48
4v3uD-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4v3vA-6bk1A:
0.0
4v3vB-6bk1A:
undetectable		 4v3vA-6bk1A:
13.48
4v3vB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.23A 4v3wA-6bk1A:
undetectable
4v3wB-6bk1A:
undetectable		 4v3wA-6bk1A:
13.48
4v3wB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 4v3xA-6bk1A:
undetectable
4v3xB-6bk1A:
undetectable		 4v3xA-6bk1A:
13.48
4v3xB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 4v3xA-6bk1A:
undetectable
4v3xB-6bk1A:
undetectable		 4v3xA-6bk1A:
13.48
4v3xB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 4v3yA-6bk1A:
undetectable
4v3yB-6bk1A:
undetectable		 4v3yA-6bk1A:
13.48
4v3yB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 4v3yA-6bk1A:
undetectable
4v3yB-6bk1A:
undetectable		 4v3yA-6bk1A:
13.48
4v3yB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 4v3zA-6bk1A:
undetectable
4v3zB-6bk1A:
undetectable		 4v3zA-6bk1A:
13.48
4v3zB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 4v3zA-6bk1A:
undetectable
4v3zB-6bk1A:
undetectable		 4v3zA-6bk1A:
13.48
4v3zB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 5w8x LIPID-A-DISACCHARIDE
SYNTHASE
(Escherichia
coli) 		5 / 12 CYH A 282
LEU A 273
ALA A 278
ALA A 264
ALA A 271
 None
None
UDP  A 401 ( 3.4A)
None
None
 1.14A 4x1iB-5w8xA:
4.7		 4x1iB-5w8xA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 2bvm TOXIN B
(Clostridioides
difficile) 		3 / 3 LEU A 265
ASP A 270
ILE A 107
 UDP  A1543 (-3.9A)
GLC  A1544 (-2.9A)
None
 0.70A 4xi3D-2bvmA:
undetectable		 4xi3D-2bvmA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3qkw NUCLEOTIDE SUGAR
SYNTHETASE-LIKE
PROTEIN
(Streptococcus
parasanguinis) 		4 / 7 TYR A 245
ILE A  13
HIS A 156
LEU A 218
 UDP  A 400 (-4.7A)
None
UDP  A 400 (-4.9A)
None
 0.99A 4xo7B-3qkwA:
undetectable		 4xo7B-3qkwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 4cvm UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D- ALANINE LIGASE
(Pseudomonas
aeruginosa) 		4 / 4 PHE A  41
ASP A  31
GLY A  51
SER A  29
 UDP  A1452 ( 4.8A)
UDP  A1452 (-3.2A)
UDP  A1452 ( 4.0A)
None
 1.46A 4xp9C-4cvmA:
0.0		 4xp9C-4cvmA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE
(Homo
sapiens) 		4 / 8 ARG A 321
ARG A 325
VAL A 138
ASP A 143
 UDP  A 501 (-3.1A)
None
None
None
 1.17A 4xqgA-4zhtA:
5.4		 4xqgA-4zhtA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5hvo ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Aspergillus
fumigatus) 		4 / 4 SER A  46
SER A 463
GLU A 394
ASP A 252
 None
None
UDP  A 501 (-1.8A)
None
 1.31A 4ymgA-5hvoA:
3.7		 4ymgA-5hvoA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1xv5 DNA
ALPHA-GLUCOSYLTRANSF
ERASE
(Escherichia
virus
T4) 		3 / 4 ARG A1204
GLY A1233
GLU A1235
 CME  A1014 (-3.7A)
UDP  A1402 ( 3.9A)
None
 0.44A 4z2dB-1xv5A:
undetectable
4z2dC-1xv5A:
2.4		 4z2dB-1xv5A:
23.12
4z2dC-1xv5A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		4 / 5 ARG A  10
GLY A 289
GLU A 310
SER A 239
 UDP  A 401 (-3.5A)
UDP  A 401 (-3.7A)
None
UDP  A 401 (-2.7A)
 1.24A 4z3oA-4nesA:
undetectable
4z3oB-4nesA:
undetectable		 4z3oA-4nesA:
20.56
4z3oB-4nesA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1fgg GLUCURONYLTRANSFERAS
E I
(Homo
sapiens) 		4 / 6 ARG A 161
ASP A 194
HIS A 308
ARG A 310
 UDP  A 337 ( 4.5A)
UDP  A 337 (-3.6A)
UNX  A 338 ( 3.2A)
UDP  A 337 (-3.6A)
 1.16A 5a06A-1fggA:
undetectable		 5a06A-1fggA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1v84 GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 1
(Homo
sapiens) 		4 / 6 ARG A 170
ASP A 195
HIS A 311
ARG A 313
 UDP  A 503 (-4.4A)
UDP  A 503 (-3.5A)
UDP  A 503 (-4.2A)
UDP  A 503 (-3.5A)
 1.01A 5a06A-1v84A:
undetectable		 5a06A-1v84A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5ad5A-6bk1A:
undetectable
5ad5B-6bk1A:
undetectable		 5ad5A-6bk1A:
13.48
5ad5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 5ad5A-6bk1A:
undetectable
5ad5B-6bk1A:
undetectable		 5ad5A-6bk1A:
13.48
5ad5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 5ad6A-6bk1A:
0.0
5ad6B-6bk1A:
undetectable		 5ad6A-6bk1A:
13.48
5ad6B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 5ad8A-6bk1A:
undetectable
5ad8B-6bk1A:
undetectable		 5ad8A-6bk1A:
13.48
5ad8B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 7 ARG A 261
VAL A  66
HIS A 263
GLU A  59
 None
None
MN  A 330 ( 3.7A)
UDP  A 332 (-2.4A)
 1.33A 5ad9A-3cknA:
undetectable
5ad9B-3cknA:
undetectable		 5ad9A-3cknA:
24.08
5ad9B-3cknA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 5adaA-6bk1A:
0.1
5adaB-6bk1A:
undetectable		 5adaA-6bk1A:
13.48
5adaB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5adbA-6bk1A:
undetectable
5adbB-6bk1A:
undetectable		 5adbA-6bk1A:
13.48
5adbB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 5adcA-6bk1A:
undetectable
5adcB-6bk1A:
undetectable		 5adcA-6bk1A:
13.48
5adcB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 5addA-6bk1A:
undetectable
5addB-6bk1A:
undetectable		 5addA-6bk1A:
13.48
5addB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.32A 5adeA-6bk1A:
undetectable
5adeB-6bk1A:
undetectable		 5adeA-6bk1A:
13.48
5adeB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 5adgA-6bk1A:
undetectable
5adgB-6bk1A:
undetectable		 5adgA-6bk1A:
13.48
5adgB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5adgA-6bk1A:
undetectable
5adgB-6bk1A:
undetectable		 5adgA-6bk1A:
13.48
5adgB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5adiA-6bk1A:
undetectable
5adiB-6bk1A:
undetectable		 5adiA-6bk1A:
13.48
5adiB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 5agkA-6bk1A:
undetectable
5agkB-6bk1A:
undetectable		 5agkA-6bk1A:
13.48
5agkB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 5aglA-6bk1A:
undetectable
5aglB-6bk1A:
undetectable		 5aglA-6bk1A:
13.48
5aglB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 5aglA-6bk1A:
undetectable
5aglB-6bk1A:
undetectable		 5aglA-6bk1A:
13.48
5aglB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 5agmA-6bk1A:
undetectable
5agmB-6bk1A:
undetectable		 5agmA-6bk1A:
13.48
5agmB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 5agnA-6bk1A:
undetectable
5agnB-6bk1A:
undetectable		 5agnA-6bk1A:
13.48
5agnB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.32A 5agnA-6bk1A:
undetectable
5agnB-6bk1A:
undetectable		 5agnA-6bk1A:
13.48
5agnB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 5agoA-6bk1A:
undetectable
5agoB-6bk1A:
undetectable		 5agoA-6bk1A:
13.48
5agoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5agpA-6bk1A:
undetectable
5agpB-6bk1A:
undetectable		 5agpA-6bk1A:
13.48
5agpB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 6 SER A 290
GLY A 354
ASP A 179
GLY A 352
 UDP  A 402 (-2.4A)
None
None
None
 0.97A 5cdpA-5xvsA:
undetectable
5cdpB-5xvsA:
2.8		 5cdpA-5xvsA:
9.59
5cdpB-5xvsA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		4 / 4 LEU A 265
ILE A 262
PRO A 191
LEU A 193
 UDP  A 402 (-4.5A)
None
None
None
 0.97A 5eb3A-4fkzA:
3.6		 5eb3A-4fkzA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		4 / 5 THR A 205
ALA A 206
THR A 282
HIS A 207
 UDP  A 402 ( 4.8A)
None
None
UD1  A 401 ( 4.0A)
 1.27A 5ecmA-4fkzA:
1.9		 5ecmA-4fkzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 2acv TRITERPENE
UDP-GLUCOSYL
TRANSFERASE UGT71G1
(Medicago
truncatula) 		5 / 9 ILE A 373
GLY A 353
LEU A 422
GLN A 382
LEU A 281
 None
None
None
UDP  A 900 ( 4.6A)
None
 1.35A 5fhzB-2acvA:
4.0		 5fhzB-2acvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.22A 5fvpA-6bk1A:
undetectable
5fvpB-6bk1A:
0.1		 5fvpA-6bk1A:
13.48
5fvpB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 5fvpA-6bk1A:
undetectable
5fvpB-6bk1A:
0.1		 5fvpA-6bk1A:
13.48
5fvpB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 5fvqA-6bk1A:
undetectable
5fvqB-6bk1A:
undetectable		 5fvqA-6bk1A:
13.48
5fvqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 5fvqA-6bk1A:
undetectable
5fvqB-6bk1A:
undetectable		 5fvqA-6bk1A:
13.48
5fvqB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5fvrA-6bk1A:
undetectable
5fvrB-6bk1A:
undetectable		 5fvrA-6bk1A:
13.48
5fvrB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 5fvsA-6bk1A:
undetectable
5fvsB-6bk1A:
undetectable		 5fvsA-6bk1A:
13.48
5fvsB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5fvsA-6bk1A:
undetectable
5fvsB-6bk1A:
undetectable		 5fvsA-6bk1A:
13.48
5fvsB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 5fvtA-6bk1A:
undetectable
5fvtB-6bk1A:
undetectable		 5fvtA-6bk1A:
13.48
5fvtB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 5fvtA-6bk1A:
undetectable
5fvtB-6bk1A:
undetectable		 5fvtA-6bk1A:
13.48
5fvtB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 5fvvA-6bk1A:
0.0
5fvvB-6bk1A:
undetectable		 5fvvA-6bk1A:
13.48
5fvvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 5fvvA-6bk1A:
0.0
5fvvB-6bk1A:
undetectable		 5fvvA-6bk1A:
13.48
5fvvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 5fvwA-6bk1A:
undetectable
5fvwB-6bk1A:
undetectable		 5fvwA-6bk1A:
13.48
5fvwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.25A 5fvxA-6bk1A:
undetectable
5fvxB-6bk1A:
undetectable		 5fvxA-6bk1A:
13.48
5fvxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 5fw0A-6bk1A:
undetectable
5fw0B-6bk1A:
undetectable		 5fw0A-6bk1A:
13.48
5fw0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 5fw0A-6bk1A:
undetectable
5fw0B-6bk1A:
undetectable		 5fw0A-6bk1A:
13.48
5fw0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 5g0nA-6bk1A:
undetectable
5g0nB-6bk1A:
undetectable		 5g0nA-6bk1A:
13.48
5g0nB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 5g0nA-6bk1A:
undetectable
5g0nB-6bk1A:
undetectable		 5g0nA-6bk1A:
13.48
5g0nB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5g0oA-6bk1A:
undetectable
5g0oB-6bk1A:
undetectable		 5g0oA-6bk1A:
13.48
5g0oB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5g0oA-6bk1A:
undetectable
5g0oB-6bk1A:
undetectable		 5g0oA-6bk1A:
13.48
5g0oB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5g0pA-6bk1A:
undetectable
5g0pB-6bk1A:
undetectable		 5g0pA-6bk1A:
13.48
5g0pB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 5g0pA-6bk1A:
undetectable
5g0pB-6bk1A:
undetectable		 5g0pA-6bk1A:
13.48
5g0pB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2ffu POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 2
(Homo
sapiens) 		5 / 12 LEU A 173
ALA A 151
SER A 109
THR A 143
ARG A 197
 None
None
None
UDP  A 601 (-3.8A)
None
 1.30A 5hnzB-2ffuA:
undetectable		 5hnzB-2ffuA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 5enz UDP-GLCNAC
2-EPIMERASE
(Staphylococcus
aureus) 		5 / 12 VAL A 265
PRO A  19
ALA A  18
VAL A  47
SER A 282
 UDP  A 401 (-3.7A)
None
None
None
UDP  A 401 (-2.7A)
 1.22A 5hv1A-5enzA:
undetectable		 5hv1A-5enzA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 9 SER A 295
GLY A 297
ALA A 276
VAL A 298
GLU A 292
 None
None
None
None
UDP  A1081 (-2.7A)
 1.50A 5i3cA-3beoA:
undetectable		 5i3cA-3beoA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 9 ARG A  10
PHE A 274
LEU A 203
ILE A 237
PHE A 238
 UDP  A 401 (-3.5A)
UDP  A 401 (-3.4A)
None
None
None
 1.34A 5i73A-4nesA:
undetectable		 5i73A-4nesA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 HIS A 247
LEU A  48
TYR A 274
PHE A 277
 UD1  A 502 (-4.0A)
None
UDP  A 501 (-4.4A)
UDP  A 501 (-3.6A)
 1.15A 5igjA-5dldA:
undetectable		 5igjA-5dldA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 TYR A 315
ASP A 117
HIS A  19
ILE A  21
 EDO  A1480 (-4.8A)
None
EDO  A1480 ( 3.8A)
UDP  A1477 (-3.7A)
 1.20A 5ih0A-2vg8A:
undetectable		 5ih0A-2vg8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4phs PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)
(Streptococcus
parasanguinis) 		5 / 12 ALA A 191
ILE A  42
TYR A  44
GLY A  30
THR A 112
 None
None
UDP  A 301 (-3.5A)
None
None
 1.01A 5jlcA-4phsA:
undetectable		 5jlcA-4phsA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5v4a GLYCOSYLTRANSFERASE
(DUF1792)
(Streptococcus
sanguinis) 		5 / 12 ALA A 191
ILE A  41
TYR A  43
GLY A  29
THR A 112
 None
None
UDP  A 301 (-3.4A)
None
None
 1.01A 5jlcA-5v4aA:
undetectable		 5jlcA-5v4aA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 2wzf GLUCOSYLTRANSFERASE
(Legionella
pneumophila) 		4 / 7 SER A 519
PRO A 522
TYR A 440
SER A 229
 UDP  A1525 (-2.8A)
None
None
UDP  A1525 (-2.8A)
 1.22A 5l1fC-2wzfA:
2.2		 5l1fC-2wzfA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		5 / 11 THR A 304
ALA A 241
GLY A 310
GLY A 309
ALA A 308
 None
UDP  A1401 (-4.3A)
UDP  A1401 (-3.6A)
UDP  A1401 (-3.5A)
UDP  A1401 (-4.3A)
 0.98A 5lf3K-2iyfA:
undetectable
5lf3L-2iyfA:
undetectable		 5lf3K-2iyfA:
20.77
5lf3L-2iyfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		5 / 11 THR A 304
ALA A 241
GLY A 310
GLY A 309
ALA A 308
 None
UDP  A1401 (-4.3A)
UDP  A1401 (-3.6A)
UDP  A1401 (-3.5A)
UDP  A1401 (-4.3A)
 0.98A 5lf3Y-2iyfA:
undetectable
5lf3Z-2iyfA:
undetectable		 5lf3Y-2iyfA:
20.77
5lf3Z-2iyfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 THR A 207
ALA A 208
VAL A 300
GLY A 288
GLY A 287
 UDP  A1081 ( 4.9A)
None
None
UDP  A1081 (-3.7A)
UDP  A1081 (-3.7A)
 0.82A 5lf7K-3beoA:
undetectable
5lf7L-3beoA:
undetectable		 5lf7K-3beoA:
18.49
5lf7L-3beoA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		5 / 11 THR A 205
ALA A 206
VAL A 298
GLY A 286
GLY A 285
 UDP  A 402 ( 4.8A)
None
None
UDP  A 402 (-3.5A)
UDP  A 402 (-3.6A)
 0.79A 5lf7K-4fkzA:
undetectable
5lf7L-4fkzA:
undetectable		 5lf7K-4fkzA:
19.79
5lf7L-4fkzA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5enz UDP-GLCNAC
2-EPIMERASE
(Staphylococcus
aureus) 		5 / 11 THR A 203
ALA A 204
VAL A 296
GLY A 284
GLY A 283
 UDP  A 401 ( 4.4A)
None
None
UDP  A 401 (-3.5A)
UDP  A 401 (-3.8A)
 0.86A 5lf7K-5enzA:
undetectable
5lf7L-5enzA:
undetectable		 5lf7K-5enzA:
20.00
5lf7L-5enzA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		5 / 11 THR A 205
ALA A 206
VAL A 298
GLY A 286
GLY A 285
 UDP  A 402 ( 4.8A)
None
None
UDP  A 402 (-3.5A)
UDP  A 402 (-3.6A)
 0.79A 5lf7Y-4fkzA:
undetectable
5lf7Z-4fkzA:
undetectable		 5lf7Y-4fkzA:
19.79
5lf7Z-4fkzA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5enz UDP-GLCNAC
2-EPIMERASE
(Staphylococcus
aureus) 		5 / 11 THR A 203
ALA A 204
VAL A 296
GLY A 284
GLY A 283
 UDP  A 401 ( 4.4A)
None
None
UDP  A 401 (-3.5A)
UDP  A 401 (-3.8A)
 0.85A 5lf7Y-5enzA:
undetectable
5lf7Z-5enzA:
undetectable		 5lf7Y-5enzA:
20.00
5lf7Z-5enzA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1gz5 ALPHA-TREHALOSE-PHOS
PHATE SYNTHASE
(Escherichia
coli) 		5 / 10 LEU A 394
ILE A 434
ALA A 372
VAL A 366
PRO A 358
 None
None
None
UDP  A 900 (-3.9A)
None
 1.31A 5m0oA-1gz5A:
0.0		 5m0oA-1gz5A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 VAL A 275
VAL A 274
ILE A 375
ALA A 372
VAL A 349
 None
UDP  A1001 ( 4.3A)
None
None
None
 1.17A 5n0sB-4whmA:
undetectable		 5n0sB-4whmA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 LEU A 442
LEU A 437
LEU A 368
ILE A 234
ALA A 375
 None
None
UDP  A 501 (-3.9A)
GOL  A 503 (-4.4A)
None
 1.15A 5nm5B-5tvgA:
undetectable		 5nm5B-5tvgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 10 ILE A 303
LEU A 203
VAL A 300
LEU A 298
GLU A 294
 None
None
None
None
UDP  A 401 (-2.7A)
 1.14A 5tixB-4nesA:
undetectable		 5tixB-4nesA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		4 / 7 THR A 193
PHE A 278
MET A 206
THR A 185
 UDP  A 501 ( 4.6A)
UDP  A 501 ( 3.3A)
SO4  A 502 (-3.7A)
None
 1.24A 5u6mA-5f84A:
7.2		 5u6mA-5f84A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		4 / 7 THR A 193
PHE A 278
MET A 206
THR A 185
 UDP  A 501 ( 4.6A)
UDP  A 501 ( 3.3A)
SO4  A 502 (-3.7A)
None
 1.28A 5u6mB-5f84A:
6.9		 5u6mB-5f84A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 5unrA-6bk1A:
undetectable
5unrB-6bk1A:
undetectable		 5unrA-6bk1A:
13.48
5unrB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 5unsA-6bk1A:
undetectable
5unsB-6bk1A:
undetectable		 5unsA-6bk1A:
13.48
5unsB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5untA-6bk1A:
undetectable
5untB-6bk1A:
undetectable		 5untA-6bk1A:
13.48
5untB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.32A 5unuA-6bk1A:
undetectable
5unuB-6bk1A:
undetectable		 5unuA-6bk1A:
13.48
5unuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.33A 5unuA-6bk1A:
undetectable
5unuB-6bk1A:
undetectable		 5unuA-6bk1A:
13.48
5unuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.34A 5unvA-6bk1A:
undetectable
5unvB-6bk1A:
undetectable		 5unvA-6bk1A:
13.48
5unvB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 5unwA-6bk1A:
undetectable
5unwB-6bk1A:
undetectable		 5unwA-6bk1A:
13.48
5unwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5unwA-6bk1A:
undetectable
5unwB-6bk1A:
undetectable		 5unwA-6bk1A:
13.48
5unwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 5unxA-6bk1A:
undetectable
5unxB-6bk1A:
undetectable		 5unxA-6bk1A:
13.48
5unxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 5uo1A-6bk1A:
undetectable
5uo1B-6bk1A:
undetectable		 5uo1A-6bk1A:
13.48
5uo1B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.31A 5uo2A-6bk1A:
undetectable
5uo2B-6bk1A:
undetectable		 5uo2A-6bk1A:
13.48
5uo2B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.24A 5uo2A-6bk1A:
undetectable
5uo2B-6bk1A:
undetectable		 5uo2A-6bk1A:
13.48
5uo2B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 5uo3A-6bk1A:
undetectable
5uo3B-6bk1A:
undetectable		 5uo3A-6bk1A:
13.48
5uo3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 5uo3A-6bk1A:
undetectable
5uo3B-6bk1A:
undetectable		 5uo3A-6bk1A:
13.48
5uo3B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 5uo4A-6bk1A:
undetectable
5uo4B-6bk1A:
undetectable		 5uo4A-6bk1A:
13.48
5uo4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.32A 5uo4A-6bk1A:
undetectable
5uo4B-6bk1A:
undetectable		 5uo4A-6bk1A:
13.48
5uo4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 5uo5A-6bk1A:
0.0
5uo5B-6bk1A:
undetectable		 5uo5A-6bk1A:
13.48
5uo5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.31A 5uo5A-6bk1A:
0.0
5uo5B-6bk1A:
undetectable		 5uo5A-6bk1A:
13.48
5uo5B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 8 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5uo7A-6bk1A:
undetectable
5uo7B-6bk1A:
undetectable		 5uo7A-6bk1A:
13.48
5uo7B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		4 / 5 ASP A 307
PRO A 312
ARG A 208
THR A 309
 None
None
UDP  A 401 ( 3.2A)
None
 1.38A 5uxcA-4nesA:
undetectable		 5uxcA-4nesA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 4pqg GLYCOSYLTRANSFERASE
GTF1
(Streptococcus
pneumoniae) 		5 / 12 VAL A  17
ARG A 328
TYR A 246
SER A 247
GLU A 332
 NAG  A 602 (-4.6A)
UDP  A 601 (-3.8A)
None
None
NAG  A 602 ( 3.9A)
 1.39A 5v1tA-4pqgA:
2.0		 5v1tA-4pqgA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 GLY A  23
HIS A 133
LYS A 236
GLU A 316
GLY A 319
 UDP  A 600 (-3.2A)
None
UDP  A 600 (-2.7A)
UDP  A 600 (-3.2A)
None
 0.98A 5vncC-3c4qA:
26.5		 5vncC-3c4qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 3c4q PREDICTED
GLYCOSYLTRANSFERASES
(Corynebacterium
glutamicum) 		5 / 10 HIS A 133
ASN A 171
LYS A 236
GLU A 316
GLY A 319
 None
None
UDP  A 600 (-2.7A)
UDP  A 600 (-3.2A)
None
 1.41A 5vncC-3c4qA:
26.5		 5vncC-3c4qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 10 GLY A 303
HIS A 438
LYS A 585
GLU A 675
GLY A 678
 UDP  A 901 ( 2.9A)
None
UDP  A 901 (-2.8A)
UDP  A 901 (-4.1A)
UDP  A 901 ( 3.7A)
 0.57A 5vncC-3s29A:
15.3		 5vncC-3s29A:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 4pqg GLYCOSYLTRANSFERASE
GTF1
(Streptococcus
pneumoniae) 		5 / 10 GLY A  16
HIS A 242
LYS A 333
GLU A 404
GLY A 407
 UDP  A 601 ( 3.0A)
NAG  A 602 (-3.9A)
UDP  A 601 (-2.8A)
NAG  A 602 (-3.6A)
UDP  A 601 ( 3.4A)
 0.67A 5vncC-4pqgA:
18.2		 5vncC-4pqgA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 5e9u GLYCOSYLTRANSFERASE
GTF1
(Streptococcus
gordonii) 		5 / 10 GLY A  16
HIS A 242
LYS A 333
GLU A 404
GLY A 407
 UDP  A 601 (-3.1A)
NAG  A 602 (-3.6A)
UDP  A 601 ( 4.6A)
None
NAG  A 602 (-3.3A)
 1.14A 5vncC-5e9uA:
17.5		 5vncC-5e9uA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 10 GLY A  16
HIS A 118
ASN A 166
LYS A 196
GLU A 267
 UDP  A 401 (-3.0A)
CL  A 404 ( 4.5A)
None
UDP  A 401 (-2.9A)
NA  A 403 (-3.6A)
 0.83A 5vncC-6ejjA:
24.4		 5vncC-6ejjA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5xyk PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 5 ASP E 204
ASN E 272
ASP E 239
ARG E  72
 None
ARG  E 401 (-4.3A)
UDP  E 403 ( 3.2A)
None
 1.44A 5vooD-5xykE:
undetectable		 5vooD-5xykE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 5vuiA-6bk1A:
undetectable
5vuiB-6bk1A:
undetectable		 5vuiA-6bk1A:
13.48
5vuiB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 5vunA-6bk1A:
undetectable
5vunB-6bk1A:
undetectable		 5vunA-6bk1A:
13.48
5vunB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5vunA-6bk1A:
undetectable
5vunB-6bk1A:
undetectable		 5vunA-6bk1A:
13.48
5vunB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5vuoA-6bk1A:
undetectable
5vuoB-6bk1A:
undetectable		 5vuoA-6bk1A:
13.48
5vuoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.25A 5vuoA-6bk1A:
undetectable
5vuoB-6bk1A:
undetectable		 5vuoA-6bk1A:
13.48
5vuoB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 5vupA-6bk1A:
undetectable
5vupB-6bk1A:
undetectable		 5vupA-6bk1A:
13.48
5vupB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 5vupA-6bk1A:
undetectable
5vupB-6bk1A:
undetectable		 5vupA-6bk1A:
13.48
5vupB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 5vutA-6bk1A:
undetectable
5vutB-6bk1A:
undetectable		 5vutA-6bk1A:
13.48
5vutB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.26A 5vutA-6bk1A:
undetectable
5vutB-6bk1A:
undetectable		 5vutA-6bk1A:
13.48
5vutB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.29A 5vuuA-6bk1A:
undetectable
5vuuB-6bk1A:
undetectable		 5vuuA-6bk1A:
13.48
5vuuB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5vuwA-6bk1A:
undetectable
5vuwB-6bk1A:
undetectable		 5vuwA-6bk1A:
13.48
5vuwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 5vuwA-6bk1A:
undetectable
5vuwB-6bk1A:
undetectable		 5vuwA-6bk1A:
13.48
5vuwB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 5vuxA-6bk1A:
undetectable
5vuxB-6bk1A:
undetectable		 5vuxA-6bk1A:
13.48
5vuxB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.24A 5vuzA-6bk1A:
undetectable
5vuzB-6bk1A:
undetectable		 5vuzA-6bk1A:
13.48
5vuzB-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.25A 5vv0A-6bk1A:
undetectable
5vv0B-6bk1A:
undetectable		 5vv0A-6bk1A:
13.48
5vv0B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5vv1A-6bk1A:
undetectable
5vv1B-6bk1A:
undetectable		 5vv1A-6bk1A:
13.48
5vv1B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 5vv2A-6bk1A:
undetectable
5vv2B-6bk1A:
undetectable		 5vv2A-6bk1A:
13.48
5vv2B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 5vv2A-6bk1A:
0.0
5vv2B-6bk1A:
undetectable		 5vv2A-6bk1A:
13.48
5vv2B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 5vv4A-6bk1A:
undetectable
5vv4B-6bk1A:
undetectable		 5vv4A-6bk1A:
13.48
5vv4B-6bk1A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1471_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 12 ARG A 309
ARG A 215
ASN A 135
THR A 100
HIS A 116
 ACT  A 505 (-4.1A)
UDP  A 501 (-3.1A)
None
None
None
 1.41A 5x7pA-5dldA:
0.1		 5x7pA-5dldA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		3 / 3 THR A 139
GLU A 352
HIS A 328
 ZIO  A1425 (-3.7A)
ZIO  A1425 (-3.8A)
UDP  A1424 (-4.0A)
 0.90A 5xioA-2iyaA:
4.9		 5xioA-2iyaA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 THR A 140
GLU A 388
HIS A 364
 TRS  A1478 ( 4.4A)
TRS  A1478 (-2.8A)
UDP  A1477 (-3.9A)
 0.88A 5xioA-2vg8A:
3.4		 5xioA-2vg8A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		3 / 3 THR A 139
GLU A 352
HIS A 328
 ZIO  A1425 (-3.7A)
ZIO  A1425 (-3.8A)
UDP  A1424 (-4.0A)
 0.91A 5xiqB-2iyaA:
3.9		 5xiqB-2iyaA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 THR A 140
GLU A 388
HIS A 364
 TRS  A1478 ( 4.4A)
TRS  A1478 (-2.8A)
UDP  A1477 (-3.9A)
 0.85A 5xiqB-2vg8A:
2.7		 5xiqB-2vg8A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE
(Streptomyces
antibioticus) 		3 / 3 THR A 139
GLU A 352
HIS A 328
 ZIO  A1425 (-3.7A)
ZIO  A1425 (-3.8A)
UDP  A1424 (-4.0A)
 0.89A 5xiqD-2iyaA:
3.1		 5xiqD-2iyaA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 THR A 140
GLU A 388
HIS A 364
 TRS  A1478 ( 4.4A)
TRS  A1478 (-2.8A)
UDP  A1477 (-3.9A)
 0.87A 5xiqD-2vg8A:
2.2		 5xiqD-2vg8A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ckn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		3 / 3 GLY A 189
VAL A 278
MET A 274
 None
None
UDP  A 332 ( 4.3A)
 0.52A 5ycpA-3cknA:
undetectable		 5ycpA-3cknA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 3hbj FLAVONOID
3-O-GLUCOSYLTRANSFER
ASE
(Medicago
truncatula) 		4 / 6 GLY A 354
THR A 384
VAL A 358
TRP A 355
 UDP  A 900 (-3.5A)
None
None
None
 1.07A 5ysiA-3hbjA:
undetectable		 5ysiA-3hbjA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 5gvv GLYCOSYL TRANSFERASE
FAMILY 8
(Streptococcus
pneumoniae) 		4 / 7 ASP A 108
LEU A 109
ILE A 229
TYR A 104
 MN  A 501 ( 1.8A)
None
UDP  A 502 (-4.3A)
None
 0.98A 5zsfA-5gvvA:
undetectable
5zsfB-5gvvA:
undetectable		 5zsfA-5gvvA:
12.21
5zsfB-5gvvA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 6 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 6auqA-6bk1A:
undetectable
6auqB-6bk1A:
undetectable		 6auqA-6bk1A:
16.87
6auqB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 6auqA-6bk1A:
undetectable
6auqB-6bk1A:
undetectable		 6auqA-6bk1A:
16.87
6auqB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 6aurA-6bk1A:
undetectable
6aurB-6bk1A:
undetectable		 6aurA-6bk1A:
16.87
6aurB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 6aurA-6bk1A:
undetectable
6aurB-6bk1A:
undetectable		 6aurA-6bk1A:
16.87
6aurB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 6ausA-6bk1A:
undetectable
6ausB-6bk1A:
undetectable		 6ausA-6bk1A:
16.87
6ausB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 6ausA-6bk1A:
undetectable
6ausB-6bk1A:
undetectable		 6ausA-6bk1A:
16.87
6ausB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 6autA-6bk1A:
undetectable
6autB-6bk1A:
undetectable		 6autA-6bk1A:
16.87
6autB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 6auuA-6bk1A:
undetectable
6auuB-6bk1A:
undetectable		 6auuA-6bk1A:
16.87
6auuB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 6auuA-6bk1A:
undetectable
6auuB-6bk1A:
undetectable		 6auuA-6bk1A:
16.87
6auuB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 6auvA-6bk1A:
undetectable
6auvB-6bk1A:
undetectable		 6auvA-6bk1A:
16.87
6auvB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 6auwA-6bk1A:
0.0
6auwB-6bk1A:
undetectable		 6auwA-6bk1A:
16.87
6auwB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 6auwA-6bk1A:
0.0
6auwB-6bk1A:
undetectable		 6auwA-6bk1A:
16.87
6auwB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 6auxA-6bk1A:
undetectable
6auxB-6bk1A:
undetectable		 6auxA-6bk1A:
16.87
6auxB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 6auxA-6bk1A:
undetectable
6auxB-6bk1A:
undetectable		 6auxA-6bk1A:
16.87
6auxB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.27A 6auyA-6bk1A:
undetectable
6auyB-6bk1A:
undetectable		 6auyA-6bk1A:
16.87
6auyB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 6auyA-6bk1A:
0.0
6auyB-6bk1A:
undetectable		 6auyA-6bk1A:
16.87
6auyB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.24A 6auzA-6bk1A:
undetectable
6auzB-6bk1A:
undetectable		 6auzA-6bk1A:
16.87
6auzB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 6auzA-6bk1A:
undetectable
6auzB-6bk1A:
undetectable		 6auzA-6bk1A:
16.87
6auzB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 6av0A-6bk1A:
undetectable
6av0B-6bk1A:
undetectable		 6av0A-6bk1A:
16.87
6av0B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 6av0A-6bk1A:
undetectable
6av0B-6bk1A:
undetectable		 6av0A-6bk1A:
16.87
6av0B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 6av1A-6bk1A:
undetectable
6av1B-6bk1A:
undetectable		 6av1A-6bk1A:
16.87
6av1B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 6av2A-6bk1A:
undetectable
6av2B-6bk1A:
undetectable		 6av2A-6bk1A:
16.87
6av2B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.25A 6av2A-6bk1A:
undetectable
6av2B-6bk1A:
undetectable		 6av2A-6bk1A:
16.87
6av2B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 6av3A-6bk1A:
undetectable
6av3B-6bk1A:
undetectable		 6av3A-6bk1A:
16.87
6av3B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.30A 6av3A-6bk1A:
undetectable
6av3B-6bk1A:
undetectable		 6av3A-6bk1A:
16.87
6av3B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.28A 6av4A-6bk1A:
undetectable
6av4B-6bk1A:
undetectable		 6av4A-6bk1A:
16.87
6av4B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 6av4A-6bk1A:
undetectable
6av4B-6bk1A:
undetectable		 6av4A-6bk1A:
16.87
6av4B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 6av5A-6bk1A:
0.0
6av5B-6bk1A:
undetectable		 6av5A-6bk1A:
16.87
6av5B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.29A 6av5A-6bk1A:
0.0
6av5B-6bk1A:
undetectable		 6av5A-6bk1A:
16.87
6av5B-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.30A 6cicA-6bk1A:
0.0
6cicB-6bk1A:
undetectable		 6cicA-6bk1A:
16.87
6cicB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.28A 6cicA-6bk1A:
0.0
6cicB-6bk1A:
undetectable		 6cicA-6bk1A:
16.87
6cicB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 ARG A 331
VAL A 317
TRP A 316
GLU A 322
 None
UDP  A 501 ( 4.8A)
None
None
 1.26A 6cidA-6bk1A:
undetectable
6cidB-6bk1A:
undetectable		 6cidA-6bk1A:
16.87
6cidB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bk1 UDP-GLYCOSYLTRANSFER
ASE 79
(Oryza
sativa) 		4 / 7 GLU A 322
ARG A 331
VAL A 317
TRP A 316
 None
None
UDP  A 501 ( 4.8A)
None
 1.27A 6cidA-6bk1A:
undetectable
6cidB-6bk1A:
undetectable		 6cidA-6bk1A:
16.87
6cidB-6bk1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		5 / 9 VAL A  71
VAL A  65
LEU A  74
GLY A  38
LEU A  40
 None
UDP  A 196 (-3.7A)
None
UDP  A 196 (-3.6A)
None
 1.14A 6czmA-4ukdA:
undetectable
6czmB-4ukdA:
undetectable		 6czmA-4ukdA:
20.44
6czmB-4ukdA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		5 / 9 VAL A  71
VAL A  65
LEU A  74
GLY A  38
LEU A  40
 None
UDP  A 196 (-3.7A)
None
UDP  A 196 (-3.6A)
None
 1.13A 6czmB-4ukdA:
undetectable
6czmC-4ukdA:
undetectable		 6czmB-4ukdA:
20.44
6czmC-4ukdA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE
(Dictyostelium
discoideum) 		5 / 9 VAL A  71
VAL A  65
LEU A  74
GLY A  38
LEU A  40
 None
UDP  A 196 (-3.7A)
None
UDP  A 196 (-3.6A)
None
 1.11A 6czmD-4ukdA:
undetectable
6czmE-4ukdA:
undetectable		 6czmD-4ukdA:
20.44
6czmE-4ukdA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 SER A 173
ASP A 168
GLY A 166
PHE A  15
ILE A 188
 None
None
UDP  A 301 (-3.5A)
None
None
 1.04A 6dwnA-3hbnA:
undetectable		 6dwnA-3hbnA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 SER A 173
ASP A 168
GLY A 166
PHE A  15
ILE A 188
 None
None
UDP  A 301 (-3.5A)
None
None
 1.07A 6dwnC-3hbnA:
undetectable		 6dwnC-3hbnA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 SER A 173
ASP A 168
GLY A 166
PHE A  15
ILE A 188
 None
None
UDP  A 301 (-3.5A)
None
None
 1.08A 6dwnD-3hbnA:
undetectable		 6dwnD-3hbnA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]
(Candida
albicans) 		4 / 5 THR A 330
THR A 377
GLN A 289
ASP A 379
 None
None
None
UDP  A 501 ( 4.9A)
 1.16A 6ectA-5huuA:
undetectable		 6ectA-5huuA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4w6q GLUCOSYLTRANSFERASE
(Streptococcus
agalactiae) 		4 / 7 ARG A 179
TYR A 242
LEU A 247
VAL A 229
 UDP  A 402 ( 3.6A)
None
None
None
 1.33A 6g2pA-4w6qA:
undetectable		 6g2pA-4w6qA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		6 / 12 GLY A  23
VAL A  27
VAL A 247
ASN A 269
PRO A 510
GLY A 512
 None
None
None
None
None
UDP  A 801 (-3.5A)
 0.77A 6gneA-5vncA:
22.7		 6gneA-5vncA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		7 / 12 GLU A  16
GLY A  23
VAL A  27
VAL A 247
ASN A 269
PRO A 510
GLY A 512
 None
None
None
None
None
None
UDP  A 801 (-3.5A)
 0.89A 6gneB-5vncA:
22.6		 6gneB-5vncA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLU A  18
GLY A  15
GLY A  16
VAL A  20
ASN A 166
 A2G  A 406 ( 3.1A)
A2G  A 406 (-3.4A)
UDP  A 401 (-3.0A)
None
None
 0.69A 6gneB-6ejjA:
26.6		 6gneB-6ejjA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLU A  18
GLY A  16
VAL A  20
ASN A 166
ARG A 191
 A2G  A 406 ( 3.1A)
UDP  A 401 (-3.0A)
None
None
UDP  A 401 (-3.5A)
 0.93A 6gneB-6ejjA:
26.6		 6gneB-6ejjA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  27
ASN A 269
GLU A 509
PRO A 510
GLY A 512
 None
None
UDP  A 801 (-3.9A)
None
UDP  A 801 (-3.5A)
 0.86A 6gnfA-5vncA:
10.1		 6gnfA-5vncA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  27
ASN A 269
GLU A 509
PRO A 510
GLY A 512
 None
None
UDP  A 801 (-3.9A)
None
UDP  A 801 (-3.5A)
 0.87A 6gnfC-5vncA:
21.0		 6gnfC-5vncA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE
(Homo
sapiens) 		5 / 12 GLY A 299
LEU A 218
VAL A 216
GLY A 140
ASP A 143
 None
UDP  A 501 (-4.3A)
None
None
None
 1.12A 6gngA-4zhtA:
14.1		 6gngA-4zhtA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3s29 SUCROSE SYNTHASE 1
(Arabidopsis
thaliana) 		5 / 12 GLY A 303
HIS A 438
ARG A 580
GLU A 675
GLY A 678
 UDP  A 901 ( 2.9A)
None
FRU  A 902 ( 3.7A)
UDP  A 901 (-4.1A)
UDP  A 901 ( 3.7A)
 0.61A 6gngA-3s29A:
16.4		 6gngA-3s29A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 4pqg GLYCOSYLTRANSFERASE
GTF1
(Streptococcus
pneumoniae) 		6 / 12 GLU A  18
GLY A  16
HIS A 242
ARG A 328
GLU A 404
GLY A 407
 None
UDP  A 601 ( 3.0A)
NAG  A 602 (-3.9A)
UDP  A 601 (-3.8A)
NAG  A 602 (-3.6A)
UDP  A 601 ( 3.4A)
 0.76A 6gngA-4pqgA:
17.3		 6gngA-4pqgA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		7 / 12 GLU A  16
GLY A  23
TRP A 170
HIS A 193
VAL A 247
PRO A 510
GLY A 512
 None
None
None
None
None
None
UDP  A 801 (-3.5A)
 0.88A 6gngA-5vncA:
21.1		 6gngA-5vncA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 193
VAL A 247
GLU A 509
PRO A 510
GLY A 512
 None
None
UDP  A 801 (-3.9A)
None
UDP  A 801 (-3.5A)
 0.94A 6gngA-5vncA:
21.1		 6gngA-5vncA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLU A  18
GLY A  16
HIS A 118
ARG A 191
GLU A 267
 A2G  A 406 ( 3.1A)
UDP  A 401 (-3.0A)
CL  A 404 ( 4.5A)
UDP  A 401 (-3.5A)
NA  A 403 (-3.6A)
 1.02A 6gngA-6ejjA:
13.5		 6gngA-6ejjA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  27
HIS A 193
VAL A 247
GLU A 509
GLY A 512
 None
None
None
UDP  A 801 (-3.9A)
UDP  A 801 (-3.5A)
 1.01A 6gngB-5vncA:
10.1		 6gngB-5vncA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  27
TRP A 170
HIS A 193
VAL A 247
GLY A 512
 None
None
None
None
UDP  A 801 (-3.5A)
 0.72A 6gngB-5vncA:
10.1		 6gngB-5vncA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 1gz5 ALPHA-TREHALOSE-PHOS
PHATE SYNTHASE
(Escherichia
coli) 		6 / 12 GLY A  21
GLY A  22
LEU A  23
GLY A 301
HIS A 132
ARG A 262
 UDP  A 900 (-3.4A)
IMD  A 902 (-3.0A)
G6P  A 901 ( 3.7A)
None
G6P  A 901 (-4.5A)
UDP  A 900 ( 3.8A)
 1.16A 6gngB-1gz5A:
22.1		 6gngB-1gz5A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 5v0t ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Paraburkholderia
xenovorans) 		5 / 12 GLY A  30
GLY A  31
LEU A  32
HIS A 142
ARG A 277
 UDP  A 501 (-3.4A)
UDP  A 501 ( 3.1A)
G6P  A 502 (-3.9A)
G6P  A 502 (-4.7A)
UDP  A 501 ( 3.9A)
 0.88A 6gngB-5v0tA:
21.9		 6gngB-5v0tA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ois CYSTEINE PROTEASE
(Xylella
fastidiosa) 		4 / 6 ASP A  44
TYR A 184
ASP A 128
GLU A 115
 UDP  A 292 (-3.7A)
UDP  A 292 (-3.2A)
None
None
 1.22A 6mn5A-3oisA:
undetectable		 6mn5A-3oisA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ckn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 7 TYR A 170
GLU A 217
ASP A 139
GLU A  59
 None
None
UDP  A 332 (-3.5A)
UDP  A 332 (-2.4A)
 1.34A 6mn5B-3cknA:
undetectable		 6mn5B-3cknA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ois CYSTEINE PROTEASE
(Xylella
fastidiosa) 		4 / 7 ASP A  44
TYR A 184
ASP A 128
GLU A 115
 UDP  A 292 (-3.7A)
UDP  A 292 (-3.2A)
None
None
 1.10A 6mn5B-3oisA:
undetectable		 6mn5B-3oisA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ois CYSTEINE PROTEASE
(Xylella
fastidiosa) 		4 / 6 ASP A  44
TYR A 184
ASP A 128
GLU A 115
 UDP  A 292 (-3.7A)
UDP  A 292 (-3.2A)
None
None
 1.03A 6mn5C-3oisA:
undetectable		 6mn5C-3oisA:
13.19