SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UD1'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 TYR A 316
HIS A 157
THR A  79
ASN A 108
 UD1  A 902 ( 4.5A)
PMP  A 901 (-3.9A)
None
None
 1.30A 1afsA-2fnuA:
undetectable		 1afsA-2fnuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		4 / 7 TYR A 316
HIS A 157
THR A  79
ASN A 108
 UD1  A 902 ( 4.5A)
PMP  A 901 (-3.9A)
None
None
 1.29A 1afsB-2fnuA:
undetectable		 1afsB-2fnuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  20
GLU A 267
LEU A 263
GLY A 100
LEU A  99
 None
UD1  A 366 (-2.6A)
UD1  A 366 (-3.8A)
None
None
 1.04A 1g50B-3s2uA:
undetectable		 1g50B-3s2uA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  20
GLU A 267
LEU A 263
GLY A 100
LEU A  99
 None
UD1  A 366 (-2.6A)
UD1  A 366 (-3.8A)
None
None
 1.04A 1g50C-3s2uA:
undetectable		 1g50C-3s2uA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		4 / 8 PHE A  31
GLY A  99
LEU A 130
VAL A 123
 None
None
None
UD1  A 501 (-4.2A)
 0.97A 1gsfA-3vcyA:
undetectable		 1gsfA-3vcyA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		4 / 8 PHE A  31
GLY A  99
LEU A 130
VAL A 123
 None
None
None
UD1  A 501 (-4.2A)
 0.98A 1gsfB-3vcyA:
undetectable		 1gsfB-3vcyA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		4 / 8 PHE A  31
GLY A  99
LEU A 130
VAL A 123
 None
None
None
UD1  A 501 (-4.2A)
 0.97A 1gsfC-3vcyA:
undetectable		 1gsfC-3vcyA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 8 PHE A  31
GLY A  99
LEU A 130
VAL A 123
 None
None
None
UD1  A 503 (-4.2A)
 1.03A 1gsfC-4r7uA:
undetectable		 1gsfC-4r7uA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		4 / 8 PHE A  31
GLY A  99
LEU A 130
VAL A 123
 None
None
None
UD1  A 501 (-4.2A)
 0.98A 1gsfD-3vcyA:
undetectable		 1gsfD-3vcyA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 2put ISOMERASE DOMAIN OF
GLUTAMINE-FRUCTOSE-6
-PHOSPHATE
TRANSAMINASE
(ISOMERIZING)
(Candida
albicans) 		4 / 8 ARG A 372
LEU A 382
VAL A 473
GLY A 474
 UD1  A5002 (-3.9A)
None
None
UD1  A5002 (-3.2A)
 1.05A 1hrkA-2putA:
1.8		 1hrkA-2putA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		4 / 5 SER A 118
THR A 119
GLU A 151
GLY A 149
 None
UD1  A 400 (-3.0A)
None
None
 1.15A 1icrA-3vpsA:
undetectable
1icrB-3vpsA:
undetectable		 1icrA-3vpsA:
22.12
1icrB-3vpsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		4 / 5 GLU A 151
GLY A 149
SER A 118
THR A 119
 None
None
None
UD1  A 400 (-3.0A)
 1.15A 1icrA-3vpsA:
undetectable
1icrB-3vpsA:
undetectable		 1icrA-3vpsA:
22.12
1icrB-3vpsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		4 / 6 GLU A 151
GLY A 149
SER A 118
THR A 119
 None
None
None
UD1  A 400 (-3.0A)
 1.16A 1icuA-3vpsA:
undetectable
1icuB-3vpsA:
undetectable		 1icuA-3vpsA:
22.12
1icuB-3vpsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		4 / 6 SER A 118
THR A 119
GLU A 151
GLY A 149
 None
UD1  A 400 (-3.0A)
None
None
 1.16A 1icuC-3vpsA:
undetectable
1icuD-3vpsA:
undetectable		 1icuC-3vpsA:
22.12
1icuD-3vpsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		4 / 5 SER A 118
THR A 119
GLU A 151
GLY A 149
 None
UD1  A 400 (-3.0A)
None
None
 1.14A 1icvC-3vpsA:
undetectable
1icvD-3vpsA:
undetectable		 1icvC-3vpsA:
22.12
1icvD-3vpsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		4 / 5 GLU A 151
GLY A 149
SER A 118
THR A 119
 None
None
None
UD1  A 400 (-3.0A)
 1.14A 1icvC-3vpsA:
undetectable
1icvD-3vpsA:
undetectable		 1icvC-3vpsA:
22.12
1icvD-3vpsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		4 / 5 GLU A 151
GLY A 149
SER A 118
THR A 119
 None
None
None
UD1  A 400 (-3.0A)
 1.16A 1kqbA-3vpsA:
undetectable
1kqbB-3vpsA:
undetectable		 1kqbA-3vpsA:
22.50
1kqbB-3vpsA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		4 / 6 GLU A 151
GLY A 149
SER A 118
THR A 119
 None
None
None
UD1  A 400 (-3.0A)
 1.15A 1kqbC-3vpsA:
undetectable
1kqbD-3vpsA:
undetectable		 1kqbC-3vpsA:
22.50
1kqbD-3vpsA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		4 / 6 ARG A 258
ASP A 132
ASP A 149
GLU A 261
 UD1  A 335 (-3.0A)
UD1  A 335 (-2.6A)
None
UD1  A 335 (-2.7A)
 1.24A 1rjdC-2gn4A:
6.4		 1rjdC-2gn4A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ARG A 121
ILE A 118
GLY A 119
ALA A 120
 UD1  A 503 (-3.8A)
None
None
None
 0.88A 1wmqA-4r7uA:
undetectable		 1wmqA-4r7uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ARG A 121
ILE A 118
GLY A 119
ALA A 120
 UD1  A 503 (-3.8A)
None
None
None
 0.88A 1wmqB-4r7uA:
undetectable		 1wmqB-4r7uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ARG A 121
ILE A 118
GLY A 119
ALA A 120
 UD1  A 503 (-3.8A)
None
None
None
 0.88A 1wpuA-4r7uA:
undetectable		 1wpuA-4r7uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ARG A 121
ILE A 118
GLY A 119
ALA A 120
 UD1  A 503 (-3.8A)
None
None
None
 0.88A 1wpuB-4r7uA:
undetectable		 1wpuB-4r7uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ARG A 121
ILE A 118
GLY A 119
ALA A 120
 UD1  A 503 (-3.8A)
None
None
None
 0.86A 1wrqA-4r7uA:
undetectable		 1wrqA-4r7uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ARG A 121
ILE A 118
GLY A 119
ALA A 120
 UD1  A 503 (-3.8A)
None
None
None
 0.88A 1wrqB-4r7uA:
undetectable		 1wrqB-4r7uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		4 / 8 THR A  96
SER A 122
ARG A 311
GLU A 157
 UD1  A 400 (-4.1A)
None
None
None
 1.49A 1xr2B-4nesA:
2.6		 1xr2B-4nesA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A 120
ILE A 131
ASN A 153
ALA A 150
ASP A  95
 None
None
None
None
UD1  A 400 ( 4.8A)
 1.16A 2ejtA-4nesA:
undetectable		 2ejtA-4nesA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 2oi6 BIFUNCTIONAL PROTEIN
GLMU
(Escherichia
coli) 		5 / 11 ILE A 202
GLU A 154
GLY A 171
THR A 170
THR A 199
 None
UD1  A4000 (-2.7A)
UD1  A4000 ( 4.7A)
None
UD1  A4000 (-3.6A)
 1.12A 2fn1B-2oi6A:
undetectable		 2fn1B-2oi6A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4mix PUTATIVE
INSECTICIDAL TOXIN
(Photorhabdus
asymbiotica) 		5 / 12 ASN A2180
ILE A2171
TYR A2274
ALA A2256
SER A2259
 None
UD1  A2502 (-4.2A)
None
UD1  A2502 (-3.6A)
UD1  A2502 (-2.9A)
 1.44A 2iyfB-4mixA:
2.3		 2iyfB-4mixA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  52
LEU A 100
ALA A  99
ARG A 193
LEU A  12
 None
None
None
None
UD1  A4000 (-4.1A)
 1.40A 2oaxE-3dj4A:
undetectable		 2oaxE-3dj4A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 12 GLU A 293
ARG A 311
ILE A  14
ASP A  95
GLU A 117
 None
None
UDP  A 401 (-3.8A)
UD1  A 400 ( 4.8A)
None
 1.29A 2qeoA-4nesA:
undetectable		 2qeoA-4nesA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		3 / 3 PRO A 199
ASN A 191
ARG A 195
 UD1  A 400 (-4.1A)
None
None
 1.09A 2qeuB-3vpsA:
undetectable		 2qeuB-3vpsA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 7 GLU A 136
ARG A 140
GLU A 212
SER A 132
 UD1  A 372 (-3.6A)
None
None
None
 1.24A 2zt7A-3beoA:
2.3		 2zt7A-3beoA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		4 / 7 GLU A 134
ARG A 138
GLU A 210
SER A 130
 UD1  A 401 (-3.6A)
None
None
None
 1.28A 2zt7A-4fkzA:
2.1		 2zt7A-4fkzA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2oi6 BIFUNCTIONAL PROTEIN
GLMU
(Escherichia
coli) 		5 / 11 LEU A  53
ALA A  13
ALA A  12
VAL A  51
GLN A  37
 None
UD1  A4000 (-3.3A)
None
None
None
 1.20A 3bszE-2oi6A:
undetectable		 3bszE-2oi6A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4mix PUTATIVE
INSECTICIDAL TOXIN
(Photorhabdus
asymbiotica) 		5 / 6 ILE A2169
LYS A2231
PHE A2234
PHE A2243
TYR A2246
 UD1  A2502 (-4.1A)
None
None
None
None
 1.40A 3elzB-4mixA:
undetectable		 3elzB-4mixA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4mix PUTATIVE
INSECTICIDAL TOXIN
(Photorhabdus
asymbiotica) 		4 / 6 ILE A2171
LYS A2231
PHE A2234
PHE A2243
 UD1  A2502 (-4.2A)
None
None
None
 1.19A 3elzB-4mixA:
undetectable		 3elzB-4mixA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 ASP A  49
LEU A  48
GLN A  70
 None
None
UD1  A 372 (-3.7A)
 0.73A 3g4lA-3beoA:
undetectable		 3g4lA-3beoA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		3 / 3 ASP A  47
LEU A  46
GLN A  68
 None
None
UD1  A 401 (-3.9A)
 0.76A 3g4lA-4fkzA:
undetectable		 3g4lA-4fkzA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 ARG A  69
ASP A  74
ASP A  68
 None
None
UD1  A 372 (-4.7A)
 0.70A 3jayA-3beoA:
undetectable		 3jayA-3beoA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		3 / 3 GLU A 129
ASP A 124
ASP A 287
 UD1  A 400 (-3.6A)
None
None
 0.78A 3jb2A-4nesA:
2.4		 3jb2A-4nesA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQZ_A_LQZA586_1
(SERUM ALBUMIN)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ARG A 121
ARG A  92
ARG A 372
LYS A  23
 UD1  A 503 (-3.8A)
None
None
UD1  A 503 ( 4.5A)
 1.43A 3jqzA-4r7uA:
undetectable		 3jqzA-4r7uA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 118
VAL A 224
ALA A 182
GLY A 183
ILE A 153
 None
None
None
UD1  A4000 ( 4.5A)
None
 0.89A 3ku1A-3dj4A:
2.5		 3ku1A-3dj4A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 118
VAL A 224
ALA A 182
GLY A 183
ILE A 153
 None
None
None
UD1  A4000 ( 4.5A)
None
 0.92A 3ku1C-3dj4A:
2.2		 3ku1C-3dj4A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		5 / 12 VAL A 164
ALA A 186
ILE A 214
LEU A 199
ILE A 168
 UD1  A 501 (-3.7A)
None
None
None
None
 1.10A 3qfxA-3vcyA:
undetectable		 3qfxA-3vcyA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		3 / 3 THR A 244
ASP A 287
GLU A 129
 None
None
UD1  A 400 (-3.6A)
 0.70A 3qowA-4nesA:
undetectable		 3qowA-4nesA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 4 SER A 305
GLY A 222
GLU A 346
 None
UD1  A 901 (-3.1A)
None
 0.69A 3raeA-1jv1A:
undetectable
3raeC-1jv1A:
undetectable		 3raeA-1jv1A:
21.76
3raeC-1jv1A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2oi6 BIFUNCTIONAL PROTEIN
GLMU
(Escherichia
coli) 		5 / 8 ALA A 158
ASP A 157
GLY A 140
ILE A 168
THR A 143
 None
None
UD1  A4000 (-3.3A)
None
None
 1.20A 3so9A-2oi6A:
undetectable		 3so9A-2oi6A:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		5 / 12 GLN A 292
GLY A 289
ASP A  95
ILE A 149
ALA A 150
 None
UDP  A 401 (-3.7A)
UD1  A 400 ( 4.8A)
None
None
 0.92A 3sudC-4nesA:
undetectable		 3sudC-4nesA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 4mix PUTATIVE
INSECTICIDAL TOXIN
(Photorhabdus
asymbiotica) 		5 / 12 ASP A2260
PRO A2348
ASP A2278
ILE A2277
ARG A2263
 UD1  A2502 (-2.9A)
UD1  A2502 (-4.1A)
CA  A2501 ( 2.7A)
UD1  A2502 (-4.5A)
UD1  A2502 (-3.1A)
 0.95A 3topA-4mixA:
undetectable		 3topA-4mixA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		5 / 12 ALA A 174
LEU A 183
MET A 159
ALA A 166
ILE A 168
 None
None
None
UD1  A 501 ( 4.7A)
None
 1.11A 3ut5B-3vcyA:
undetectable		 3ut5B-3vcyA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  20
GLU A 267
LEU A 263
GLY A 100
LEU A  99
 None
UD1  A 366 (-2.6A)
UD1  A 366 (-3.8A)
None
None
 1.15A 3uudA-3s2uA:
undetectable		 3uudA-3s2uA:
22.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		7 / 7 ARG A  92
ALA A  93
ILE A  95
TRP A  96
ARG A 121
HIS A 126
GLY A 165
 None
UD1  A 503 ( 4.8A)
None
None
UD1  A 503 (-3.8A)
UD1  A 503 ( 4.8A)
UD1  A 503 (-3.3A)
 0.24A 3v4tH-4r7uA:
67.1		 3v4tH-4r7uA:
80.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2oi6 BIFUNCTIONAL PROTEIN
GLMU
(Escherichia
coli) 		5 / 12 LEU A 100
ALA A  89
ILE A 198
LEU A  11
VAL A  54
 None
None
None
UD1  A4000 (-4.1A)
None
 0.97A 3w67C-2oi6A:
undetectable		 3w67C-2oi6A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 166
ALA A 253
ILE A 243
LEU A 186
VAL A 256
 None
None
UD1  A 366 (-4.0A)
None
None
 1.06A 3w67C-3s2uA:
undetectable		 3w67C-3s2uA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		5 / 11 VAL A  27
ALA A  13
LEU A  37
VAL A  80
LEU A  56
 None
UD1  A4000 (-4.8A)
None
None
None
 1.01A 3zosA-3dj4A:
undetectable
3zosB-3dj4A:
undetectable		 3zosA-3dj4A:
21.78
3zosB-3dj4A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		4 / 8 SER A 316
SER A 317
ASN A 320
GLY A 172
 None
None
None
UD1  A 335 ( 4.0A)
 0.87A 4af0A-2gn4A:
undetectable		 4af0A-2gn4A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		6 / 12 ILE A  78
LEU A  37
GLY A 113
THR A 111
VAL A   9
ILE A  53
 None
None
UD1  A4000 (-4.1A)
None
None
None
 1.07A 4c9lA-3dj4A:
undetectable		 4c9lA-3dj4A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		6 / 12 ILE A  78
LEU A  37
GLY A 113
THR A 111
VAL A   9
ILE A  53
 None
None
UD1  A4000 (-4.1A)
None
None
None
 1.04A 4c9lB-3dj4A:
undetectable		 4c9lB-3dj4A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		6 / 12 ILE A  78
LEU A  37
GLY A 113
THR A 111
VAL A   9
ILE A  53
 None
None
UD1  A4000 (-4.1A)
None
None
None
 1.14A 4c9oA-3dj4A:
undetectable		 4c9oA-3dj4A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		6 / 12 ILE A  78
LEU A  37
GLY A 113
THR A 111
VAL A   9
ILE A  53
 None
None
UD1  A4000 (-4.1A)
None
None
None
 1.14A 4c9oB-3dj4A:
undetectable		 4c9oB-3dj4A:
21.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		3 / 3 ARG A  92
TRP A  96
GLY A 165
 None
None
UD1  A 503 (-3.3A)
 0.60A 4e7cA-4r7uA:
59.9		 4e7cA-4r7uA:
80.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		5 / 5 ARG A  92
ILE A  95
TRP A  96
HIS A 126
GLY A 165
 None
None
None
UD1  A 503 ( 4.8A)
UD1  A 503 (-3.3A)
 0.57A 4e7cC-4r7uA:
61.0		 4e7cC-4r7uA:
80.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 261
VAL A 265
THR A 264
LEU A 263
ASN A 160
 UD1  A 366 (-3.2A)
None
UD1  A 366 (-2.8A)
UD1  A 366 (-3.8A)
None
 1.01A 4f84A-3s2uA:
4.0		 4f84A-3s2uA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4mix PUTATIVE
INSECTICIDAL TOXIN
(Photorhabdus
asymbiotica) 		5 / 11 ASN A2180
ILE A2171
TYR A2274
ALA A2256
SER A2259
 None
UD1  A2502 (-4.2A)
None
UD1  A2502 (-3.6A)
UD1  A2502 (-2.9A)
 1.44A 4m83B-4mixA:
undetectable		 4m83B-4mixA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		4 / 6 GLU A 189
ASP A 306
GLU A 326
ARG A 121
 UD1  A 501 ( 4.9A)
UD1  A 501 (-2.8A)
None
PO4  A 502 (-3.0A)
 1.13A 4ntxA-3vcyA:
undetectable
4ntxC-3vcyA:
undetectable		 4ntxA-3vcyA:
22.16
4ntxC-3vcyA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 GLU A 189
ASP A 306
GLU A 326
ARG A 121
 None
UD1  A 503 (-2.7A)
None
UD1  A 503 (-3.8A)
 1.03A 4ntxA-4r7uA:
undetectable
4ntxC-4r7uA:
undetectable		 4ntxA-4r7uA:
22.11
4ntxC-4r7uA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 100
LEU A  97
GLY A  96
LEU A  12
VAL A 109
 None
None
None
UD1  A4000 (-4.1A)
None
 1.05A 4ok1A-3dj4A:
undetectable		 4ok1A-3dj4A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 100
LEU A  97
GLY A  96
LEU A  12
VAL A 109
 None
None
None
UD1  A4000 (-4.1A)
None
 1.16A 4olmA-3dj4A:
undetectable		 4olmA-3dj4A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 2oi6 BIFUNCTIONAL PROTEIN
GLMU
(Escherichia
coli) 		5 / 12 ASP A 200
ILE A 201
ILE A 198
GLY A 171
ILE A 202
 None
None
None
UD1  A4000 ( 4.7A)
None
 0.98A 4q1yB-2oi6A:
undetectable		 4q1yB-2oi6A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 8 ASN A 251
PRO A 250
PHE A 219
TYR A 244
 None
UD1  A 502 (-4.6A)
None
None
 1.36A 4v2zC-5dldA:
undetectable		 4v2zC-5dldA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		3 / 3 ASP A  98
ARG A 302
PRO A 131
 UD1  A 401 ( 4.9A)
None
None
 1.06A 4wanC-4fkzA:
undetectable		 4wanC-4fkzA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		5 / 12 GLU A 191
GLY A 302
ALA A 298
ILE A 328
ASP A 232
 None
None
None
UD1  A 503 (-4.7A)
None
 1.19A 4xe5A-4r7uA:
undetectable		 4xe5A-4r7uA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		5 / 10 GLY A 176
VAL A 175
VAL A 182
MET A 239
LEU A 242
 None
None
None
UD1  A 335 (-3.2A)
None
 1.17A 4yb6A-2gn4A:
undetectable
4yb6E-2gn4A:
undetectable		 4yb6A-2gn4A:
23.45
4yb6E-2gn4A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		5 / 10 GLY A 176
VAL A 175
VAL A 182
MET A 239
LEU A 242
 None
None
None
UD1  A 335 (-3.2A)
None
 1.16A 4yb6B-2gn4A:
1.3
4yb6C-2gn4A:
undetectable		 4yb6B-2gn4A:
23.45
4yb6C-2gn4A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		5 / 10 GLY A 176
VAL A 175
VAL A 182
MET A 239
LEU A 242
 None
None
None
UD1  A 335 (-3.2A)
None
 1.23A 4yb6C-2gn4A:
undetectable
4yb6F-2gn4A:
undetectable		 4yb6C-2gn4A:
23.45
4yb6F-2gn4A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		5 / 10 MET A 239
LEU A 242
GLY A 176
VAL A 175
VAL A 182
 UD1  A 335 (-3.2A)
None
None
None
None
 1.22A 4yb6A-2gn4A:
undetectable
4yb6D-2gn4A:
undetectable		 4yb6A-2gn4A:
23.45
4yb6D-2gn4A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		5 / 10 MET A 239
LEU A 242
GLY A 176
VAL A 175
VAL A 182
 UD1  A 335 (-3.2A)
None
None
None
None
 1.23A 4yb6D-2gn4A:
undetectable
4yb6E-2gn4A:
undetectable		 4yb6D-2gn4A:
23.45
4yb6E-2gn4A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		5 / 10 MET A 239
LEU A 242
GLY A 176
VAL A 175
VAL A 182
 UD1  A 335 (-3.2A)
None
None
None
None
 1.15A 4yb6B-2gn4A:
undetectable
4yb6F-2gn4A:
undetectable		 4yb6B-2gn4A:
23.45
4yb6F-2gn4A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 7 THR A  73
LEU A  76
THR A  98
LEU A 101
 None
None
UD1  A 502 (-4.2A)
None
 0.96A 4z91F-5dldA:
undetectable
4z91G-5dldA:
undetectable
4z91H-5dldA:
undetectable
4z91I-5dldA:
undetectable
4z91J-5dldA:
undetectable		 4z91F-5dldA:
22.83
4z91G-5dldA:
22.83
4z91H-5dldA:
22.83
4z91I-5dldA:
22.83
4z91J-5dldA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		5 / 12 GLY A 110
MET A 109
GLY A 172
LEU A 129
HIS A  86
 None
None
UD1  A 335 ( 4.0A)
NDP  A 334 (-3.8A)
None
 1.23A 4ze1A-2gn4A:
undetectable		 4ze1A-2gn4A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 128
ILE A 120
LEU A 134
GLY A 100
GLY A 261
 None
None
None
None
UD1  A 366 (-3.2A)
 0.87A 5d4uC-3s2uA:
5.6		 5d4uC-3s2uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 128
ILE A 120
LEU A 134
GLY A 100
GLY A 261
 None
None
None
None
UD1  A 366 (-3.2A)
 0.89A 5d4uD-3s2uA:
undetectable		 5d4uD-3s2uA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
subtilis) 		4 / 5 THR A 205
ALA A 206
THR A 282
HIS A 207
 UDP  A 402 ( 4.8A)
None
None
UD1  A 401 ( 4.0A)
 1.27A 5ecmA-4fkzA:
1.9		 5ecmA-4fkzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		3 / 3 THR A 244
ASP A 287
GLU A 129
 None
None
UD1  A 400 (-3.6A)
 0.68A 5fa8A-4nesA:
undetectable		 5fa8A-4nesA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A   9
GLY A 101
GLY A  14
ARG A 163
GLY A  37
 None
None
UD1  A 366 (-3.1A)
UD1  A 366 (-3.4A)
None
 0.99A 5gwxA-3s2uA:
4.3		 5gwxA-3s2uA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		4 / 5 GLY A   8
THR A  35
GLN A  70
THR A  96
 None
None
UD1  A 400 ( 4.0A)
UD1  A 400 (-4.1A)
 1.14A 5h5fA-4nesA:
undetectable		 5h5fA-4nesA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1lrk UDP-GLUCOSE
4-EPIMERASE
(Escherichia
coli) 		4 / 6 ARG A 231
ASP A 130
GLY A 294
ASP A 295
 UD1  A 341 (-4.0A)
None
None
UD1  A 341 (-3.5A)
 1.13A 5hp1A-1lrkA:
undetectable		 5hp1A-1lrkA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		4 / 5 HIS A 247
LEU A  48
TYR A 274
PHE A 277
 UD1  A 502 (-4.0A)
None
UDP  A 501 (-4.4A)
UDP  A 501 (-3.6A)
 1.15A 5igjA-5dldA:
undetectable		 5igjA-5dldA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1lrk UDP-GLUCOSE
4-EPIMERASE
(Escherichia
coli) 		5 / 8 VAL A 273
ILE A 217
ALA A 216
VAL A 207
PHE A 276
 None
UD1  A 341 (-4.5A)
None
None
None
 1.34A 5l94A-1lrkA:
undetectable		 5l94A-1lrkA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3vps NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Streptomyces
chartreusis) 		5 / 12 VAL A  59
HIS A  75
LEU A  76
ALA A  77
THR A 119
 NAD  A 401 (-4.1A)
None
NAD  A 401 (-4.2A)
NAD  A 401 (-3.6A)
UD1  A 400 (-3.0A)
 1.10A 5nd3B-3vpsA:
6.4		 5nd3B-3vpsA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		3 / 3 LYS A 183
HIS A 157
HIS A 284
 UD1  A 902 ( 3.3A)
PMP  A 901 (-3.9A)
None
 1.40A 5oexA-2fnuA:
undetectable		 5oexA-2fnuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		3 / 3 LYS A 183
HIS A 157
HIS A 284
 UD1  A 902 ( 3.3A)
PMP  A 901 (-3.9A)
None
 1.43A 5oexB-2fnuA:
undetectable		 5oexB-2fnuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		3 / 3 LYS A 183
HIS A 157
HIS A 284
 UD1  A 902 ( 3.3A)
PMP  A 901 (-3.9A)
None
 1.42A 5oexC-2fnuA:
undetectable		 5oexC-2fnuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 2fnu AMINOTRANSFERASE
(Helicobacter
pylori) 		3 / 3 LYS A 183
HIS A 157
HIS A 284
 UD1  A 902 ( 3.3A)
PMP  A 901 (-3.9A)
None
 1.36A 5oexD-2fnuA:
undetectable		 5oexD-2fnuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3dj4 BIFUNCTIONAL PROTEIN
GLMU
(Mycobacterium
tuberculosis) 		6 / 11 ASP A 114
GLY A  15
GLY A  17
LEU A  37
SER A  35
LEU A  28
 MG  A 496 ( 2.6A)
UD1  A4000 (-3.6A)
None
None
None
None
 1.34A 5twjD-3dj4A:
undetectable		 5twjD-3dj4A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 6bwc POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
CAPD
(Bacillus
thuringiensis) 		3 / 3 HIS A  88
SER A 176
ARG A 174
 UD1  A 402 ( 3.9A)
UD1  A 402 (-4.3A)
NAP  A 401 (-3.8A)
 1.01A 5u63A-6bwcA:
3.7		 5u63A-6bwcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		4 / 6 ASN A  97
THR A  71
ILE A 131
GLU A 129
 UD1  A 400 (-3.4A)
None
None
UD1  A 400 (-3.6A)
 1.34A 5uigA-4nesA:
undetectable		 5uigA-4nesA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 4r7u UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ALA A  93
PRO A 113
VAL A  88
ASP A  50
 UD1  A 503 ( 4.8A)
None
None
None
 0.82A 5umd2-4r7uA:
undetectable
5umdF-4r7uA:
undetectable		 5umd2-4r7uA:
10.80
5umdF-4r7uA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		6 / 12 GLY A 111
GLY A 224
GLY A 222
HIS A 352
GLU A 379
PHE A 386
 UD1  A 901 (-3.5A)
None
UD1  A 901 (-3.1A)
None
None
None
 1.31A 5vimB-1jv1A:
undetectable		 5vimB-1jv1A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A 151
GLY A 166
GLY A 143
ALA A 124
VAL A 159
 None
None
UD1  A1263 ( 3.7A)
None
None
 0.92A 5w4zB-2jf3A:
undetectable		 5w4zB-2jf3A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 3s2u UDP-N-ACETYLGLUCOSAM
INE--N-ACETYLMURAMYL
-(PENTAPEPTIDE)
PYROPHOSPHORYL-UNDEC
APRENOL
N-ACETYLGLUCOSAMINE
TRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 187
LEU A 186
GLN A 217
ALA A 240
 None
None
UD1  A 366 (-3.6A)
None
 0.81A 5xu8A-3s2uA:
undetectable		 5xu8A-3s2uA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1lrk UDP-GLUCOSE
4-EPIMERASE
(Escherichia
coli) 		3 / 3 ALA A 125
VAL A  86
TYR A 149
 None
UD1  A 341 (-4.3A)
NAD  A 340 (-4.6A)
 0.63A 5zmqH-1lrkA:
undetectable		 5zmqH-1lrkA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 2gn4 UDP-GLCNAC C6
DEHYDRATASE
(Helicobacter
pylori) 		5 / 9 VAL A  93
HIS A  92
LEU A 146
ALA A 134
ASP A 132
 UD1  A 335 ( 4.9A)
UD1  A 335 (-3.7A)
None
None
UD1  A 335 (-2.6A)
 1.36A 6c2mB-2gn4A:
undetectable		 6c2mB-2gn4A:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		5 / 12 ARG A 121
ILE A 118
ASN A  24
ARG A 398
ASP A  50
 PO4  A 502 (-3.0A)
None
UD1  A 501 (-3.3A)
FFQ  A 500 ( 3.0A)
None
 1.31A 6ekuA-3vcyA:
undetectable		 6ekuA-3vcyA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 6bwc POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
CAPD
(Bacillus
thuringiensis) 		4 / 6 SER A 164
ALA A 144
THR A 140
ALA A 129
 None
None
None
UD1  A 402 (-3.6A)
 1.17A 6ma6A-6bwcA:
undetectable		 6ma6A-6bwcA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_B_LLLB302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)		 3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Aliivibrio
fischeri) 		5 / 10 ASP A 124
GLY A 129
ASP A 212
THR A 213
SER A 163
 UD1  A 501 (-3.4A)
None
None
None
UD1  A 501 (-2.4A)
 1.45A 6mn1B-3vcyA:
0.0		 6mn1B-3vcyA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Methanocaldococc
us
jannaschii) 		4 / 8 ASP A 137
ARG A 133
GLU A 117
GLU A 129
 None
None
None
UD1  A 400 (-3.6A)
 1.30A 6mn4C-4nesA:
1.9		 6mn4C-4nesA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Burkholderia
vietnamiensis) 		5 / 6 THR A  10
LEU A  44
MET A  17
THR A 100
LEU A  61
 UD1  A 502 ( 4.2A)
None
None
None
None
 1.36A 6mvxA-5dldA:
undetectable
6mvxB-5dldA:
undetectable
6mvxC-5dldA:
undetectable		 6mvxA-5dldA:
20.49
6mvxB-5dldA:
20.49
6mvxC-5dldA:
20.49