SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UAP'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_A_SAMA2001_1 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	4pxq	D-GLUCURONYL C5 EPIMERASE B (Danio rerio)	4 / 6	TYR A 468 TYR A 528 GLY A 479 TYR A 546	None SGN A 804 (-4.3A) None UAP A 801 ( 3.6A)	1.20A	2g72A-4pxqA: undetectable	2g72A-4pxqA: 17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_1 (PUTATIVE METHYLTRANSFERASE BUD23)	4pxq	D-GLUCURONYL C5 EPIMERASE B (Danio rerio)	4 / 5	GLN A 185 LEU A 188 SER A 189 ASP A 325	UAP A 801 (-3.6A) None None None	1.29A	4qtuD-4pxqA: undetectable	4qtuD-4pxqA: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UAC_A_ACRA501_2 (CARBOHYDRATE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT1 FAMILY (TC 3.A.1.1.-))	4pxq	D-GLUCURONYL C5 EPIMERASE B (Danio rerio)	4 / 7	SER A 124 TRP A 544 ASP A 545 THR A 548	None None UAP A 801 (-3.6A) None	1.27A	4uacA-4pxqA: undetectable	4uacA-4pxqA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N5D_A_SAMA306_1 (METHYLTRANSFERASE)	4pxq	D-GLUCURONYL C5 EPIMERASE B (Danio rerio)	4 / 7	LEU A 484 SER A 420 ILE A 181 ASN A 478	None None SGN A 802 (-4.4A) UAP A 801 ( 4.6A)	1.04A	5n5dA-4pxqA: undetectable	5n5dA-4pxqA: 16.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2G72_A_SAMA2001_1","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","4pxq","D-GLUCURONYL C5 EPIMERASE B","Danio rerio",4,"TYR A 468;TYR A 528;GLY A 479;TYR A 546","None;SGN A 804 (-4.3A);None;UAP A 801 ( 3.6A)","1.20A","2g72A-4pxqA:undetectable",null],["4QTU_D_SAMD301_1","PUTATIVE METHYLTRANSFERASE BUD23","4pxq","D-GLUCURONYL C5 EPIMERASE B","Danio rerio",4,"GLN A 185;LEU A 188;SER A 189;ASP A 325","UAP A 801 (-3.6A);None;None;None","1.29A","4qtuD-4pxqA:undetectable","2g72A-4pxqA:17.94"],["4UAC_A_ACRA501_2","CARBOHYDRATE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT1 FAMILY (TC 3.A.1.1.-)","4pxq","D-GLUCURONYL C5 EPIMERASE B","Danio rerio",4,"SER A 124;TRP A 544;ASP A 545;THR A 548","None;None;UAP A 801 (-3.6A);None","1.27A","4uacA-4pxqA:undetectable","4qtuD-4pxqA:16.50"],["5N5D_A_SAMA306_1","METHYLTRANSFERASE","4pxq","D-GLUCURONYL C5 EPIMERASE B","Danio rerio",4,"LEU A 484;SER A 420;ILE A 181;ASN A 478","None;None;SGN A 802 (-4.4A);UAP A 801 ( 4.6A)","1.04A","5n5dA-4pxqA:undetectable","4uacA-4pxqA:22.35"]]