SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'UAH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 5irp ALANINE RACEMASE 2
(Bacillus
subtilis) 		5 / 11 SER A  47
TYR A  43
GLU A  69
GLY A  70
LEU A  73
 None
UAH  A 402 (-4.7A)
None
None
None
 1.40A 1i9jH-5irpA:
undetectable
1i9jL-5irpA:
undetectable		 1i9jH-5irpA:
21.34
1i9jL-5irpA:
18.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 5irp ALANINE RACEMASE 2
(Bacillus
subtilis) 		4 / 8 LYS A  39
TYR A  43
ARG A 139
TYR A 364
 UAH  A 402 ( 4.0A)
UAH  A 402 (-4.7A)
UAH  A 402 (-3.4A)
TRS  A 403 ( 3.3A)
 0.24A 1xqlA-5irpA:
50.2
1xqlB-5irpA:
49.9		 1xqlA-5irpA:
42.36
1xqlB-5irpA:
42.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 5irp ALANINE RACEMASE 2
(Bacillus
subtilis) 		4 / 8 LYS A  39
TYR A  43
ARG A 139
TYR A 364
 UAH  A 402 ( 4.0A)
UAH  A 402 (-4.7A)
UAH  A 402 (-3.4A)
TRS  A 403 ( 3.3A)
 0.32A 1xqlA-5irpA:
50.2
1xqlB-5irpA:
49.9		 1xqlA-5irpA:
42.36
1xqlB-5irpA:
42.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5irp ALANINE RACEMASE 2
(Bacillus
subtilis) 		4 / 5 GLN A 184
THR A 181
THR A 210
HIS A 169
 None
None
UAH  A 402 (-3.5A)
UAH  A 402 (-3.6A)
 1.14A 3g1uC-5irpA:
undetectable		 3g1uC-5irpA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5irp ALANINE RACEMASE 2
(Bacillus
subtilis) 		4 / 8 ILE A 228
VAL A  12
LEU A 251
ILE A  10
 UAH  A 402 (-3.7A)
None
None
None
 0.74A 4r38A-5irpA:
undetectable		 4r38A-5irpA:
15.71