SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TUM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		5 / 12 ASN A 172
ASP A 168
ILE A 118
GLY A  90
ILE A  89
 TUM  A 401 (-3.4A)
None
None
None
None
 1.49A 1q8jA-5jnqA:
undetectable		 1q8jA-5jnqA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 5jnq PHOSPHO-N-ACETYLMURA
MOYL-PENTAPEPTIDE-TR
ANSFERASE
([Clostridium]
bolteae) 		4 / 5 LEU A 177
ASP A 175
MET A 286
LEU A 295
 None
TUM  A 401 (-3.6A)
None
None
 1.24A 2qxsA-5jnqA:
undetectable		 2qxsA-5jnqA:
21.15