SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TUD'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QX6_A_ML1A233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5epo	7-ALPHA-HYDROXYSTERO ID DEYDROGENASE (Clostridium sardiniense)	4 / 6	ILE A 146 PHE A 208 GLY A 248 GLY A 247	None TUD A 302 ( 4.6A) None None	0.80A	2qx6A-5epoA: 4.0 2qx6B-5epoA: 4.1	2qx6A-5epoA: 21.32 2qx6B-5epoA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XR4_B_AG2B511_1 (HOMOSPERMIDINE SYNTHASE)	5epo	7-ALPHA-HYDROXYSTERO ID DEYDROGENASE (Clostridium sardiniense)	3 / 3	VAL A 96 PHE A 204 ARG A 205	None TUD A 302 (-4.8A) None	0.97A	4xr4B-5epoA: 9.4	4xr4B-5epoA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A7M_A_ACTA1923_0 (BETA-XYLOSIDASE)	5epo	7-ALPHA-HYDROXYSTERO ID DEYDROGENASE (Clostridium sardiniense)	3 / 3	ASP A 99 ARG A 155 TYR A 158	None TUD A 302 (-4.2A) TUD A 302 ( 4.5A)	1.02A	5a7mA-5epoA: 5.5	5a7mA-5epoA: 16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A7M_B_ACTB1924_0 (BETA-XYLOSIDASE)	5epo	7-ALPHA-HYDROXYSTERO ID DEYDROGENASE (Clostridium sardiniense)	3 / 3	ASP A 99 ARG A 155 TYR A 158	None TUD A 302 (-4.2A) TUD A 302 ( 4.5A)	1.04A	5a7mB-5epoA: 5.4	5a7mB-5epoA: 16.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QX6_A_ML1A233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","5epo","7-ALPHA-HYDROXYSTEROID DEYDROGENASE","Clostridium sardiniense",4,"ILE A 146;PHE A 208;GLY A 248;GLY A 247","None;TUD A 302 ( 4.6A);None;None","0.80A","2qx6A-5epoA:4.0;2qx6B-5epoA:4.1",null],["4XR4_B_AG2B511_1","HOMOSPERMIDINE SYNTHASE","5epo","7-ALPHA-HYDROXYSTEROID DEYDROGENASE","Clostridium sardiniense",3,"VAL A  96;PHE A 204;ARG A 205","None;TUD A 302 (-4.8A);None","0.97A","4xr4B-5epoA:9.4","2qx6A-5epoA:21.32;2qx6B-5epoA:21.32"],["5A7M_A_ACTA1923_0","BETA-XYLOSIDASE","5epo","7-ALPHA-HYDROXYSTEROID DEYDROGENASE","Clostridium sardiniense",3,"ASP A  99;ARG A 155;TYR A 158","None;TUD A 302 (-4.2A);TUD A 302 ( 4.5A)","1.02A","5a7mA-5epoA:5.5","4xr4B-5epoA:20.62"],["5A7M_B_ACTB1924_0","BETA-XYLOSIDASE","5epo","7-ALPHA-HYDROXYSTEROID DEYDROGENASE","Clostridium sardiniense",3,"ASP A  99;ARG A 155;TYR A 158","None;TUD A 302 (-4.2A);TUD A 302 ( 4.5A)","1.04A","5a7mB-5epoA:5.4","5a7mA-5epoA:16.34"]]