SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TTN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 5iqj UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		3 / 3 HIS A  10
GLU A  11
HIS A  14
 None
TTN  A 204 ( 4.6A)
None
 0.20A 3kecB-5iqjA:
undetectable		 3kecB-5iqjA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1gz4 NAD-DEPENDENT MALIC
ENZYME
(Homo
sapiens) 		5 / 12 GLY A 465
GLY A 463
PHE A 443
ASN A 466
ILE A 319
 None
None
None
TTN  A 603 (-2.8A)
None
 1.03A 4n49A-1gz4A:
4.0		 4n49A-1gz4A:
21.00