SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TQP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3frk QDTB
(Thermoanaerobact
erium
thermosaccharoly
ticum) 		5 / 10 LEU A 307
SER A 342
PHE A   5
THR A 284
ALA A 185
 TQP  A 374 (-4.8A)
None
None
None
TQP  A 374 (-3.3A)
 1.37A 1wygA-3frkA:
undetectable		 1wygA-3frkA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3frk QDTB
(Thermoanaerobact
erium
thermosaccharoly
ticum) 		3 / 3 ASP A 157
LEU A  61
GLY A  60
 TQP  A 374 (-2.8A)
TQP  A 374 (-4.0A)
TQP  A 374 (-3.2A)
 0.55A 4xmfA-3frkA:
undetectable		 4xmfA-3frkA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3frk QDTB
(Thermoanaerobact
erium
thermosaccharoly
ticum) 		6 / 12 GLY A  60
GLY A 179
SER A 212
LEU A 231
GLY A 195
GLY A  58
 TQP  A 374 (-3.2A)
None
None
None
None
None
 1.40A 5zhmB-3frkA:
undetectable		 5zhmB-3frkA:
21.99