SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TNE'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UBO_B_ADNB353_2 (ADENOSINE KINASE)	1ipf	TROPINONE REDUCTASE-II (Datura stramonium)	4 / 5	SER A 146 ILE A 21 TYR A 159 GLY A 190	TNE A 262 ( 2.9A) NDP A 261 (-4.1A) TNE A 262 ( 4.2A) NDP A 261 ( 4.9A)	0.96A	3uboB-1ipfA: 6.4	3uboB-1ipfA: 24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UBO_B_ADNB353_2 (ADENOSINE KINASE)	1ipf	TROPINONE REDUCTASE-II (Datura stramonium)	4 / 5	SER A 148 ILE A 144 TYR A 159 GLY A 190	TNE A 262 (-2.9A) NDP A 261 (-4.6A) TNE A 262 ( 4.2A) NDP A 261 ( 4.9A)	0.99A	3uboB-1ipfA: 6.4	3uboB-1ipfA: 24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KMM_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	1ipf	TROPINONE REDUCTASE-II (Datura stramonium)	4 / 5	LEU A 210 ARG A 221 PRO A 189 SER A 146	TNE A 262 (-4.9A) None NDP A 261 ( 4.1A) TNE A 262 ( 2.9A)	1.28A	4kmmB-1ipfA: 2.7	4kmmB-1ipfA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y03_B_SALB801_1 (PROTEIN POLYBROMO-1)	1xhl	SHORT-CHAIN DEHYDROGENASE/REDUCT ASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II (Caenorhabditis elegans)	4 / 5	LEU A 211 TYR A 212 ALA A 192 ILE A 222	None None TNE A1279 (-4.0A) None	1.15A	4y03B-1xhlA: undetectable	4y03B-1xhlA: 18.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3UBO_B_ADNB353_2","ADENOSINE KINASE","1ipf","TROPINONE REDUCTASE-II","Datura stramonium",4,"SER A 146;ILE A  21;TYR A 159;GLY A 190","TNE A 262 ( 2.9A);NDP A 261 (-4.1A);TNE A 262 ( 4.2A);NDP A 261 ( 4.9A)","0.96A","3uboB-1ipfA:6.4",null],["3UBO_B_ADNB353_2","ADENOSINE KINASE","1ipf","TROPINONE REDUCTASE-II","Datura stramonium",4,"SER A 148;ILE A 144;TYR A 159;GLY A 190","TNE A 262 (-2.9A);NDP A 261 (-4.6A);TNE A 262 ( 4.2A);NDP A 261 ( 4.9A)","0.99A","3uboB-1ipfA:6.4","3uboB-1ipfA:24.21"],["4KMM_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","1ipf","TROPINONE REDUCTASE-II","Datura stramonium",4,"LEU A 210;ARG A 221;PRO A 189;SER A 146","TNE A 262 (-4.9A);None;NDP A 261 ( 4.1A);TNE A 262 ( 2.9A)","1.28A","4kmmB-1ipfA:2.7","3uboB-1ipfA:24.21"],["4Y03_B_SALB801_1","PROTEIN POLYBROMO-1","1xhl","SHORT-CHAIN DEHYDROGENASE\/REDUCTASE FAMILY MEMBER (5L265), PUTATIVE TROPINONE REDUCTASE-II","Caenorhabditis elegans",4,"LEU A 211;TYR A 212;ALA A 192;ILE A 222","None;None;TNE A1279 (-4.0A);None","1.15A","4y03B-1xhlA:undetectable","4kmmB-1ipfA:21.47"]]