SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'THH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ARG A 359
ASP A 431
ASN A 452
ASP A 519
GLY A 558
SER A 560
ARG A 573
 None
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
 1.26A 1q8jA-3k13A:
12.3		 1q8jA-3k13A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
ASP A 431
ASN A 452
ASP A 519
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.47A 1q8jA-3k13A:
12.3		 1q8jA-3k13A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASN A 361
ASP A 431
GLY A 558
SER A 560
PHE A 564
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
None
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.79A 1q8jA-3k13A:
12.3		 1q8jA-3k13A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
ASP A 431
ASN A 452
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.52A 1q8jB-3k13A:
12.3		 1q8jB-3k13A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
GLY A 558
SER A 560
ASN A 561
ARG A 573
 THH  A 642 ( 4.7A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 0.91A 2e7fA-3k13A:
29.7		 2e7fA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASP A 431
ASN A 452
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.28A 2e7fA-3k13A:
29.7		 2e7fA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 GLU A 358
ASN A 452
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.26A 2e7fB-3k13A:
29.8		 2e7fB-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 GLU A 358
ASP A 431
ASN A 452
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.29A 2ogyA-3k13A:
29.6		 2ogyA-3k13A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 GLU A 358
ASP A 431
ASN A 452
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.27A 2ogyB-3k13A:
29.8		 2ogyB-3k13A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
ASP A 519
GLY A 558
SER A 560
ASN A 561
 THH  A 642 ( 4.7A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
 0.84A 2ycjA-3k13A:
29.6		 2ycjA-3k13A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 431
ASN A 452
ASP A 519
GLY A 558
SER A 560
ASN A 561
ILE A 593
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-4.2A)
 0.28A 2ycjA-3k13A:
29.6		 2ycjA-3k13A:
29.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 396
VAL A 478
GLY A 558
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
 1.30A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 431
GLY A 357
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
None
 1.20A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
GLY A 364
ASP A 431
GLY A 357
ARG A 573
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.1A)
 1.26A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		10 / 12 GLU A 358
ASN A 361
GLY A 364
ARG A 366
ASP A 431
VAL A 478
GLY A 558
SER A 560
ASN A 561
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-4.2A)
 0.02A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 431
VAL A 478
GLY A 558
SER A 560
ARG A 567
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.4A)
THH  A 642 (-4.2A)
 0.64A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 452
ASP A 519
ARG A 573
 THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.1A)
 0.06A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 396
VAL A 478
GLY A 558
ASN A 561
ARG A 573
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 1.30A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 431
ASN A 452
GLY A 357
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
None
 1.47A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
GLY A 364
ASP A 431
ASN A 452
ARG A 567
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
 1.19A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 431
ASN A 452
VAL A 478
GLY A 557
ILE A 593
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
None
None
THH  A 642 (-4.2A)
 1.11A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		12 / 12 GLU A 358
ASN A 361
GLY A 364
ARG A 366
ASP A 431
ASN A 452
VAL A 478
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.12A 3k13B-3k13A:
50.5		 3k13B-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 396
VAL A 478
GLY A 558
ASN A 561
PHE A 564
ARG A 573
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
None
THH  A 642 (-3.1A)
 1.24A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
GLY A 364
ARG A 366
ASP A 431
GLY A 357
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
None
 1.24A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 398
VAL A 478
GLY A 558
PHE A 564
ILE A 593
 None
None
THH  A 642 (-3.3A)
None
THH  A 642 (-4.2A)
 1.19A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		12 / 12 GLU A 358
ASN A 361
GLY A 364
ARG A 366
ASP A 431
VAL A 478
GLY A 558
SER A 560
ASN A 561
PHE A 564
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.2A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
None
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.18A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 452
ASP A 519
ARG A 567
 THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.4A)
 0.29A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 1.00A 3t3sB-3k13A:
undetectable		 3t3sB-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.93A 3t3sC-3k13A:
undetectable		 3t3sC-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.92A 3t3sD-3k13A:
undetectable		 3t3sD-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.92A 3t3sE-3k13A:
undetectable		 3t3sE-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.99A 3t3sF-3k13A:
undetectable		 3t3sF-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 361
ASP A 396
ASP A 519
GLY A 558
ARG A 573
 GOL  A 643 (-3.1A)
THH  A 642 ( 4.7A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
THH  A 642 (-3.1A)
 1.48A 4djeA-3k13A:
29.1		 4djeA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASN A 361
ASP A 431
ASP A 519
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.66A 4djeA-3k13A:
29.1		 4djeA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
ASN A 452
ASP A 519
GLY A 558
ASN A 561
 THH  A 642 ( 4.7A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
 1.29A 4djeB-3k13A:
28.8		 4djeB-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASP A 396
ASP A 431
ASN A 452
ASP A 519
GLY A 558
SER A 560
ASN A 561
ARG A 573
 THH  A 642 ( 3.5A)
THH  A 642 ( 4.7A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 0.59A 4djeB-3k13A:
28.8		 4djeB-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASN A 361
ASP A 519
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.45A 4djfA-3k13A:
29.2		 4djfA-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 GLU A 358
ASP A 396
ASP A 431
ASN A 452
GLY A 558
SER A 560
ARG A 573
 THH  A 642 ( 3.5A)
THH  A 642 ( 4.7A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
 0.53A 4djfB-3k13A:
29.1		 4djfB-3k13A:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.91A 4ejgA-3k13A:
undetectable		 4ejgA-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.86A 4ejgB-3k13A:
undetectable		 4ejgB-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 557
GLY A 558
ASN A 561
ILE A 356
 None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
None
 0.95A 4fglD-3k13A:
undetectable		 4fglD-3k13A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 GLU A 358
ASN A 361
ASP A 431
ASP A 519
GLY A 558
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.4A)
THH  A 642 (-3.3A)
THH  A 642 (-4.2A)
 0.59A 4o1eA-3k13A:
27.8		 4o1eA-3k13A:
29.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 358
ASN A 361
ASP A 431
GLY A 558
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.3A)
THH  A 642 (-4.2A)
 0.63A 4o1eB-3k13A:
27.5		 4o1eB-3k13A:
29.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE A 564
SER A 563
ASN A 361
ASP A 431
 None
None
GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
 1.33A 5kpcA-3k13A:
undetectable		 5kpcA-3k13A:
20.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.39A 5vooA-3k13A:
39.0		 5vooA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASN A 361
ASP A 431
ASN A 452
ASP A 519
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 0.28A 5vooA-3k13A:
39.0		 5vooA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-4.2A)
 0.37A 5vooB-3k13A:
38.9		 5vooB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_B_C2FB702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASP A 396
ASN A 452
ASP A 519
ASN A 561
ARG A 573
 THH  A 642 ( 4.7A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 1.31A 5vooB-3k13A:
38.9		 5vooB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_B_C2FB702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASP A 431
ASN A 452
ASP A 519
ASN A 561
ARG A 573
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 0.25A 5vooB-3k13A:
38.9		 5vooB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		8 / 12 GLU A 358
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.37A 5vooC-3k13A:
38.9		 5vooC-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASN A 361
ASP A 431
ASN A 452
ASP A 519
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 0.26A 5vooC-3k13A:
38.9		 5vooC-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASN A 361
MET A 429
VAL A 478
GLY A 558
SER A 560
PHE A 564
ILE A 593
 GOL  A 643 (-3.1A)
None
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
None
THH  A 642 (-4.2A)
 0.73A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 398
ASP A 396
MET A 429
GLY A 558
ILE A 593
 None
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 (-4.2A)
 0.97A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
MET A 429
VAL A 478
GLY A 592
ILE A 356
 THH  A 642 ( 4.7A)
None
None
None
None
 1.15A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
MET A 429
VAL A 478
GLY A 558
SER A 560
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-4.2A)
 0.35A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASP A 396
ASN A 452
ASP A 519
ASN A 561
ARG A 573
 THH  A 642 ( 4.7A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 1.34A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_D_C2FD3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASP A 431
ASN A 452
ASP A 519
ASN A 561
ARG A 573
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
 0.28A 5vooD-3k13A:
38.4		 5vooD-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 396
MET A 429
VAL A 478
GLY A 592
ILE A 356
 THH  A 642 ( 4.7A)
None
None
None
None
 1.10A 5vooE-3k13A:
38.5		 5vooE-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
GLY A 364
ASP A 396
MET A 429
VAL A 478
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.39A 5vooE-3k13A:
38.5		 5vooE-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 5 ASN A 361
ASP A 431
ASN A 452
ASP A 519
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 0.28A 5vooE-3k13A:
38.5		 5vooE-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		9 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.35A 5vooF-3k13A:
38.2		 5vooF-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_F_C2FF3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 396
ASN A 452
ASP A 519
ASN A 561
 THH  A 642 ( 4.7A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 1.39A 5vooF-3k13A:
38.2		 5vooF-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOO_F_C2FF3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 431
ASN A 452
ASP A 519
ASN A 561
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 ( 3.3A)
 0.23A 5vooF-3k13A:
38.2		 5vooF-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASN A 361
GLY A 364
ASP A 431
VAL A 478
GLY A 558
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
 1.43A 5vopA-3k13A:
39.5		 5vopA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 398
ASP A 396
GLY A 558
ASN A 561
ILE A 593
 None
THH  A 642 ( 4.7A)
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
THH  A 642 (-4.2A)
 0.93A 5vopA-3k13A:
39.5		 5vopA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		10 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.35A 5vopA-3k13A:
39.5		 5vopA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 431
ASN A 452
ASP A 519
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
 0.14A 5vopA-3k13A:
39.5		 5vopA-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASN A 361
GLY A 364
ASP A 431
VAL A 478
GLY A 558
ASN A 561
 GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 (-3.3A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
 1.46A 5vopB-3k13A:
39.0		 5vopB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASN A 398
ASP A 396
VAL A 478
GLY A 558
ASN A 561
ILE A 593
 None
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
THH  A 642 ( 3.3A)
THH  A 642 (-4.2A)
 1.09A 5vopB-3k13A:
39.0		 5vopB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		10 / 12 GLU A 358
ASN A 361
GLY A 364
ASP A 396
VAL A 478
GLY A 558
SER A 560
ASN A 561
ARG A 573
ILE A 593
 THH  A 642 ( 3.5A)
GOL  A 643 (-3.1A)
THH  A 642 (-3.7A)
THH  A 642 ( 4.7A)
None
THH  A 642 (-3.3A)
K  A 644 ( 3.4A)
THH  A 642 ( 3.3A)
THH  A 642 (-3.1A)
THH  A 642 (-4.2A)
 0.31A 5vopB-3k13A:
39.0		 5vopB-3k13A:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 431
ASN A 452
ASP A 519
 THH  A 642 (-3.3A)
THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
 0.10A 5vopB-3k13A:
39.0		 5vopB-3k13A:
34.19