SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TEC'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK3_A_T44A3001_1 (SERUM ALBUMIN)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 11	TRP A 163 PRO A 93 LEU A 173 HIS A 196 ALA A 184	TEC A 404 (-4.6A) None None TEC A 404 (-4.1A) None	1.46A	1hk3A-4q38A: undetectable	1hk3A-4q38A: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3C_A_PNXA1435_1 (CHITINASE)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	4 / 6	TRP A 260 GLY A 194 PHE A 181 SER A 182	TEC A 404 (-4.0A) None None None	1.19A	2a3cA-4q38A: undetectable	2a3cA-4q38A: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3C_B_PNXB2434_1 (CHITINASE)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	4 / 6	TRP A 260 GLY A 194 PHE A 181 SER A 182	TEC A 404 (-4.0A) None None None	1.22A	2a3cB-4q38A: undetectable	2a3cB-4q38A: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_C_VIAC903_2 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	3 / 3	ASN A 286 ILE A 149 MET A 161	None None TEC A 404 (-4.3A)	0.62A	2h42C-4q38A: undetectable	2h42C-4q38A: 19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_A_CELA682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 12	TYR A 209 LEU A 204 ALA A 216 GLY A 234 SER A 236	None COA A 403 (-4.6A) None TEC A 404 ( 3.9A) COA A 403 (-3.1A)	0.98A	3ln1A-4q38A: undetectable	3ln1A-4q38A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_A_CELA682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 12	VAL A 197 TYR A 209 LEU A 204 ALA A 216 GLY A 234	TEC A 404 ( 4.2A) None COA A 403 (-4.6A) None TEC A 404 ( 3.9A)	0.89A	3ln1A-4q38A: undetectable	3ln1A-4q38A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_B_CELB682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 12	TYR A 209 LEU A 204 ALA A 216 GLY A 234 SER A 236	None COA A 403 (-4.6A) None TEC A 404 ( 3.9A) COA A 403 (-3.1A)	1.00A	3ln1B-4q38A: undetectable	3ln1B-4q38A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_B_CELB682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 12	VAL A 197 TYR A 209 LEU A 204 ALA A 216 GLY A 234	TEC A 404 ( 4.2A) None COA A 403 (-4.6A) None TEC A 404 ( 3.9A)	0.91A	3ln1B-4q38A: undetectable	3ln1B-4q38A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 12	TYR A 209 LEU A 204 ALA A 216 GLY A 234 SER A 236	None COA A 403 (-4.6A) None TEC A 404 ( 3.9A) COA A 403 (-3.1A)	0.98A	3ln1C-4q38A: undetectable	3ln1C-4q38A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 12	VAL A 197 TYR A 209 LEU A 204 ALA A 216 GLY A 234	TEC A 404 ( 4.2A) None COA A 403 (-4.6A) None TEC A 404 ( 3.9A)	0.89A	3ln1C-4q38A: undetectable	3ln1C-4q38A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_D_CELD682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 12	VAL A 197 TYR A 209 LEU A 204 ALA A 216 GLY A 234	TEC A 404 ( 4.2A) None COA A 403 (-4.6A) None TEC A 404 ( 3.9A)	0.90A	3ln1D-4q38A: undetectable	3ln1D-4q38A: 19.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MFL_B_GCSB502_1 (PUTATIVE UNCHARACTERIZED PROTEIN TCP24 TEICOPLANIN PSEUDOAGLYCONE)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 6	GLN A 142 MET A 161 TRP A 163 TRP A 164 PHE A 281	TEC A 404 ( 4.0A) TEC A 404 (-4.3A) TEC A 404 (-4.6A) TEC A 404 (-3.7A) COA A 403 (-3.4A)	0.66A	4mflA-4q38A: 51.3	4mflA-4q38A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MFP_B_GCSB503_1 (PUTATIVE UNCHARACTERIZED PROTEIN TCP24 TEICOPLANIN PSEUDOAGLYCONE)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 5	GLN A 142 MET A 161 TRP A 163 TRP A 164 PHE A 281	TEC A 404 ( 4.0A) TEC A 404 (-4.3A) TEC A 404 (-4.6A) TEC A 404 (-3.7A) COA A 403 (-3.4A)	0.34A	4mfpA-4q38A: 50.5	4mfpA-4q38A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MFQ_B_GCSB503_1 (PUTATIVE UNCHARACTERIZED PROTEIN TCP24 TEICOPLANIN PSEUDOAGLYCONE)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 6	GLN A 142 MET A 161 TRP A 163 TRP A 164 PHE A 281	TEC A 404 ( 4.0A) TEC A 404 (-4.3A) TEC A 404 (-4.6A) TEC A 404 (-3.7A) COA A 403 (-3.4A)	0.73A	4mfqA-4q38A: 50.8	4mfqA-4q38A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q36_A_GCSA404_1 (PUTATIVE UNCHARACTERIZED PROTEIN TCP24)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 5	MET A 161 TRP A 163 TRP A 164 HIS A 196 PHE A 281	TEC A 404 (-4.3A) TEC A 404 (-4.6A) TEC A 404 (-3.7A) TEC A 404 (-4.1A) COA A 403 (-3.4A)	0.13A	4q36A-4q38A: 50.9	4q36A-4q38A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZJ_F_AZ1F2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAR-DAR-DAR)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	5 / 7	GLY A 234 SER A 235 GLY A 318 VAL A 320 LEU A 262	TEC A 404 ( 3.9A) None None None None	1.28A	5izjB-4q38A: undetectable	5izjB-4q38A: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_A_CELA602_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4q38	PUTATIVE UNCHARACTERIZED PROTEIN TCP24 (Actinoplanes teichomyceticus)	6 / 12	VAL A 197 TYR A 209 LEU A 204 ALA A 216 GLY A 234 SER A 236	TEC A 404 ( 4.2A) None COA A 403 (-4.6A) None TEC A 404 ( 3.9A) COA A 403 (-3.1A)	1.22A	5jw1A-4q38A: undetectable	5jw1A-4q38A: 21.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK3_A_T44A3001_1","SERUM ALBUMIN","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"TRP A 163;PRO A  93;LEU A 173;HIS A 196;ALA A 184","TEC A 404 (-4.6A);None;None;TEC A 404 (-4.1A);None","1.46A","1hk3A-4q38A:undetectable",null],["2A3C_A_PNXA1435_1","CHITINASE","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",4,"TRP A 260;GLY A 194;PHE A 181;SER A 182","TEC A 404 (-4.0A);None;None;None","1.19A","2a3cA-4q38A:undetectable","1hk3A-4q38A:19.20"],["2A3C_B_PNXB2434_1","CHITINASE","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",4,"TRP A 260;GLY A 194;PHE A 181;SER A 182","TEC A 404 (-4.0A);None;None;None","1.22A","2a3cB-4q38A:undetectable","2a3cA-4q38A:21.14"],["2H42_C_VIAC903_2","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",3,"ASN A 286;ILE A 149;MET A 161","None;None;TEC A 404 (-4.3A)","0.62A","2h42C-4q38A:undetectable","2a3cB-4q38A:21.14"],["3LN1_A_CELA682_1","PROSTAGLANDIN G\/H SYNTHASE 2","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"TYR A 209;LEU A 204;ALA A 216;GLY A 234;SER A 236","None;COA A 403 (-4.6A);None;TEC A 404 ( 3.9A);COA A 403 (-3.1A)","0.98A","3ln1A-4q38A:undetectable","2h42C-4q38A:19.89"],["3LN1_A_CELA682_1","PROSTAGLANDIN G\/H SYNTHASE 2","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"VAL A 197;TYR A 209;LEU A 204;ALA A 216;GLY A 234","TEC A 404 ( 4.2A);None;COA A 403 (-4.6A);None;TEC A 404 ( 3.9A)","0.89A","3ln1A-4q38A:undetectable","3ln1A-4q38A:19.76"],["3LN1_B_CELB682_1","PROSTAGLANDIN G\/H SYNTHASE 2","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"TYR A 209;LEU A 204;ALA A 216;GLY A 234;SER A 236","None;COA A 403 (-4.6A);None;TEC A 404 ( 3.9A);COA A 403 (-3.1A)","1.00A","3ln1B-4q38A:undetectable","3ln1A-4q38A:19.76"],["3LN1_B_CELB682_1","PROSTAGLANDIN G\/H SYNTHASE 2","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"VAL A 197;TYR A 209;LEU A 204;ALA A 216;GLY A 234","TEC A 404 ( 4.2A);None;COA A 403 (-4.6A);None;TEC A 404 ( 3.9A)","0.91A","3ln1B-4q38A:undetectable","3ln1B-4q38A:19.76"],["3LN1_C_CELC682_1","PROSTAGLANDIN G\/H SYNTHASE 2","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"TYR A 209;LEU A 204;ALA A 216;GLY A 234;SER A 236","None;COA A 403 (-4.6A);None;TEC A 404 ( 3.9A);COA A 403 (-3.1A)","0.98A","3ln1C-4q38A:undetectable","3ln1B-4q38A:19.76"],["3LN1_C_CELC682_1","PROSTAGLANDIN G\/H SYNTHASE 2","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"VAL A 197;TYR A 209;LEU A 204;ALA A 216;GLY A 234","TEC A 404 ( 4.2A);None;COA A 403 (-4.6A);None;TEC A 404 ( 3.9A)","0.89A","3ln1C-4q38A:undetectable","3ln1C-4q38A:19.76"],["3LN1_D_CELD682_1","PROSTAGLANDIN G\/H SYNTHASE 2","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"VAL A 197;TYR A 209;LEU A 204;ALA A 216;GLY A 234","TEC A 404 ( 4.2A);None;COA A 403 (-4.6A);None;TEC A 404 ( 3.9A)","0.90A","3ln1D-4q38A:undetectable","3ln1C-4q38A:19.76"],["4MFL_B_GCSB502_1","PUTATIVE UNCHARACTERIZED PROTEIN TCP24;TEICOPLANIN PSEUDOAGLYCONE","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"GLN A 142;MET A 161;TRP A 163;TRP A 164;PHE A 281","TEC A 404 ( 4.0A);TEC A 404 (-4.3A);TEC A 404 (-4.6A);TEC A 404 (-3.7A);COA A 403 (-3.4A)","0.66A","4mflA-4q38A:51.3","3ln1D-4q38A:19.76"],["4MFP_B_GCSB503_1","PUTATIVE UNCHARACTERIZED PROTEIN TCP24;TEICOPLANIN PSEUDOAGLYCONE","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"GLN A 142;MET A 161;TRP A 163;TRP A 164;PHE A 281","TEC A 404 ( 4.0A);TEC A 404 (-4.3A);TEC A 404 (-4.6A);TEC A 404 (-3.7A);COA A 403 (-3.4A)","0.34A","4mfpA-4q38A:50.5","4mflA-4q38A:97.68"],["4MFQ_B_GCSB503_1","PUTATIVE UNCHARACTERIZED PROTEIN TCP24;TEICOPLANIN PSEUDOAGLYCONE","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"GLN A 142;MET A 161;TRP A 163;TRP A 164;PHE A 281","TEC A 404 ( 4.0A);TEC A 404 (-4.3A);TEC A 404 (-4.6A);TEC A 404 (-3.7A);COA A 403 (-3.4A)","0.73A","4mfqA-4q38A:50.8","4mfpA-4q38A:97.68"],["4Q36_A_GCSA404_1","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"MET A 161;TRP A 163;TRP A 164;HIS A 196;PHE A 281","TEC A 404 (-4.3A);TEC A 404 (-4.6A);TEC A 404 (-3.7A);TEC A 404 (-4.1A);COA A 403 (-3.4A)","0.13A","4q36A-4q38A:50.9","4mfqA-4q38A:97.68"],["5IZJ_F_AZ1F2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAR-DAR-DAR","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",5,"GLY A 234;SER A 235;GLY A 318;VAL A 320;LEU A 262","TEC A 404 ( 3.9A);None;None;None;None","1.28A","5izjB-4q38A:undetectable","4q36A-4q38A:100.00"],["5JW1_A_CELA602_1","PROSTAGLANDIN G\/H SYNTHASE 2","4q38","PUTATIVE UNCHARACTERIZED PROTEIN TCP24","Actinoplanes teichomyceticus",6,"VAL A 197;TYR A 209;LEU A 204;ALA A 216;GLY A 234;SER A 236","TEC A 404 ( 4.2A);None;COA A 403 (-4.6A);None;TEC A 404 ( 3.9A);COA A 403 (-3.1A)","1.22A","5jw1A-4q38A:undetectable","5izjB-4q38A:20.27"]]