SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TE7'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		4 / 7 ASN A  66
GLY A  68
THR A  71
SER A  60
 None
TE7  A   1 ( 4.1A)
None
None
 1.21A 2o5yH-3te7A:
undetectable
2o5yL-3te7A:
undetectable		 2o5yH-3te7A:
22.49
2o5yL-3te7A:
25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 7 GLY A  68
GLN A 122
PHE A 126
ILE A 128
PHE A 178
 TE7  A   1 ( 4.1A)
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
TE7  A   1 (-3.6A)
 0.19A 2qmzA-3te7A:
38.9
2qmzB-3te7A:
39.5		 2qmzA-3te7A:
100.00
2qmzB-3te7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		4 / 7 GLY A  68
GLN A 122
PHE A 126
PHE A 178
 TE7  A   1 ( 4.1A)
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
TE7  A   1 (-3.6A)
 0.20A 2qwxA-3te7A:
39.7
2qwxB-3te7A:
39.0		 2qwxA-3te7A:
100.00
2qwxB-3te7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		6 / 7 GLY A  68
THR A  71
CYH A 121
GLN A 122
PHE A 126
PHE A 178
 TE7  A   1 ( 4.1A)
None
None
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
TE7  A   1 (-3.6A)
 0.20A 2qx4A-3te7A:
39.6
2qx4B-3te7A:
38.9		 2qx4A-3te7A:
100.00
2qx4B-3te7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		4 / 6 GLY A  68
GLN A 122
PHE A 126
PHE A 178
 TE7  A   1 ( 4.1A)
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
TE7  A   1 (-3.6A)
 0.20A 2qx6A-3te7A:
39.4
2qx6B-3te7A:
39.0		 2qx6A-3te7A:
100.00
2qx6B-3te7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 5 VAL A  69
PHE A 126
ILE A 128
PHE A 131
PHE A 178
 None
TE7  A   1 (-4.3A)
None
None
TE7  A   1 (-3.6A)
 0.32A 3owxB-3te7A:
39.8		 3owxB-3te7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		4 / 6 GLN A 122
ILE A 128
PRO A 129
PHE A 131
 TE7  A   1 ( 4.3A)
None
None
None
 1.02A 4fgkA-3te7A:
38.9		 4fgkA-3te7A:
98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 6 GLN A 122
PHE A 126
PRO A 129
PHE A 131
PHE A 178
 TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
None
TE7  A   1 (-3.6A)
 0.51A 4fgkA-3te7A:
38.9		 4fgkA-3te7A:
98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 10 ASN A  66
VAL A  69
GLN A 122
PHE A 126
PHE A 178
 None
None
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
TE7  A   1 (-3.6A)
 0.18A 4fgkA-3te7A:
38.9
4fgkB-3te7A:
39.6		 4fgkA-3te7A:
98.28
4fgkB-3te7A:
98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 12 VAL A  69
GLN A 122
PHE A 126
ILE A 128
PHE A 178
 None
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
TE7  A   1 (-3.6A)
 0.51A 4fglA-3te7A:
38.6
4fglB-3te7A:
39.3		 4fglA-3te7A:
98.28
4fglB-3te7A:
98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 11 HIS A  72
GLN A 122
PHE A 126
ILE A 128
PHE A 178
 None
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
TE7  A   1 (-3.6A)
 0.21A 4fglA-3te7A:
38.6
4fglB-3te7A:
39.3		 4fglA-3te7A:
98.28
4fglB-3te7A:
98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		8 / 8 ASN A  66
GLY A  68
VAL A  69
HIS A  72
GLN A 122
PHE A 126
ILE A 128
PHE A 178
 None
TE7  A   1 ( 4.1A)
None
None
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
TE7  A   1 (-3.6A)
 0.53A 4fglD-3te7A:
38.9		 4fglD-3te7A:
98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		7 / 7 ASN A  66
GLY A  68
VAL A  69
GLN A 122
PHE A 126
ILE A 128
PHE A 178
 None
TE7  A   1 ( 4.1A)
None
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
TE7  A   1 (-3.6A)
 0.63A 4fglC-3te7A:
38.5		 4fglC-3te7A:
98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 6 GLY A  68
GLN A 122
PHE A 126
ILE A 128
PHE A 178
 TE7  A   1 ( 4.1A)
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
TE7  A   1 (-3.6A)
 0.72A 4qogA-3te7A:
39.8
4qogB-3te7A:
38.8		 4qogA-3te7A:
100.00
4qogB-3te7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 11 GLN A 122
PHE A 126
ILE A 128
PHE A 131
PHE A 178
 TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
None
TE7  A   1 (-3.6A)
 0.61A 4qoiA-3te7A:
39.7
4qoiB-3te7A:
39.0		 4qoiA-3te7A:
100.00
4qoiB-3te7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]
(Homo
sapiens) 		5 / 11 GLY A  68
GLN A 122
PHE A 126
PHE A 131
PHE A 178
 TE7  A   1 ( 4.1A)
TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
TE7  A   1 (-3.6A)
 0.61A 4qoiA-3te7A:
39.7
4qoiB-3te7A:
39.0		 4qoiA-3te7A:
100.00
4qoiB-3te7A:
100.00