SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TDB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.08A 1kifA-1cwuA:
4.6		 1kifA-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.08A 1kifB-1cwuA:
4.7		 1kifB-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.08A 1kifC-1cwuA:
4.7		 1kifC-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.08A 1kifD-1cwuA:
4.7		 1kifD-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.08A 1kifE-1cwuA:
4.7		 1kifE-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.08A 1kifF-1cwuA:
4.6		 1kifF-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.08A 1kifG-1cwuA:
4.7		 1kifG-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.08A 1kifH-1cwuA:
4.7		 1kifH-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.09A 1ve9A-1cwuA:
4.6		 1ve9A-1cwuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 8 TYR A 198
PHE A 246
ALA A 240
MET A 250
 TDB  A 502 (-4.5A)
None
TDB  A 502 ( 3.1A)
None
 1.04A 1x8vA-1cwuA:
undetectable		 1x8vA-1cwuA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.12A 2du8G-1cwuA:
4.7		 2du8G-1cwuA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 1cwu ENOYL ACP REDUCTASE
(Brassica
napus) 		4 / 5 TYR A 188
TYR A 198
ILE A 244
GLY A 234
 TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
 1.13A 2du8J-1cwuA:
4.6		 2du8J-1cwuA:
21.41