SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TCB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 2o9r BETA-GLUCOSIDASE B
(Paenibacillus
polymyxa) 		5 / 10 GLY A 175
HIS A 181
ALA A 194
ALA A 195
ILE A 198
 None
TCB  A 500 ( 4.6A)
None
None
None
 0.98A 1likA-2o9rA:
undetectable		 1likA-2o9rA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 2o9r BETA-GLUCOSIDASE B
(Paenibacillus
polymyxa) 		3 / 3 ASP A 124
TRP A 402
SER A  81
 None
TCB  A 500 ( 3.6A)
None
 0.93A 4lrhB-2o9rA:
undetectable		 4lrhB-2o9rA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 2o9r BETA-GLUCOSIDASE B
(Paenibacillus
polymyxa) 		3 / 3 ASP A 124
TRP A 402
SER A  81
 None
TCB  A 500 ( 3.6A)
None
 1.01A 4lrhF-2o9rA:
undetectable		 4lrhF-2o9rA:
16.70