SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'TAD'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1HXW_B_RITB301_1 (HIV-1 PROTEASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 9 | GLY A 288ASP A 261GLY A 235VAL A 247ILE A 238 | NoneTAD A 901 (-2.3A)NoneNoneNone | 0.95A | 1hxwA-1lrtA:undetectable | 1hxwA-1lrtA:14.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1JR1_A_MOAA1332_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 6 / 11 | ASP A 261SER A 262SER A 263ASN A 291GLY A 314GLY A 409 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)TAD A 901 (-3.9A)IMP A 801 ( 3.2A) | 0.82A | 1jr1A-1lrtA:46.0 | 1jr1A-1lrtA:26.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1JR1_B_MOAB1333_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 8 | ASP A 261SER A 263ASN A 291GLY A 314GLY A 409 | TAD A 901 (-2.3A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)TAD A 901 (-3.9A)IMP A 801 ( 3.2A) | 0.37A | 1jr1B-1lrtA:45.9 | 1jr1B-1lrtA:26.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ME7_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 7 / 8 | ASP A 261SER A 262SER A 263ASN A 291ILE A 313GLY A 314GLY A 409 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)TAD A 901 (-4.1A)TAD A 901 (-3.9A)IMP A 801 ( 3.2A) | 0.33A | 1me7A-1lrtA:57.8 | 1me7A-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ME7_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 6 / 8 | SER A 262SER A 263ILE A 313GLY A 314CYH A 319GLY A 409 | TAD A 901 ( 2.6A)TAD A 901 (-2.7A)TAD A 901 (-4.1A)TAD A 901 (-3.9A)IMP A 801 (-4.0A)IMP A 801 ( 3.2A) | 0.60A | 1me7A-1lrtA:57.8 | 1me7A-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 10 | ASP A 261ASN A 291GLY A 315GLU A 408GLY A 407 | TAD A 901 (-2.3A)IMP A 801 ( 4.6A)NoneNoneIMP A 801 (-3.2A) | 1.17A | 1mehA-1lrtA:58.0 | 1mehA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 6 / 10 | ASP A 261ASN A 291GLY A 316GLU A 408GLY A 409ARG A 414 | TAD A 901 (-2.3A)IMP A 801 ( 4.6A)IMP A 801 (-3.6A)NoneIMP A 801 ( 3.2A)None | 1.42A | 1mehA-1lrtA:58.0 | 1mehA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 10 | ASP A 261ASN A 291GLY A 359GLU A 408GLY A 407 | TAD A 901 (-2.3A)IMP A 801 ( 4.6A)IMP A 801 (-3.3A)NoneIMP A 801 (-3.2A) | 1.28A | 1mehA-1lrtA:58.0 | 1mehA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 6 / 10 | ASP A 261ASN A 291ILE A 313GLY A 314GLU A 408GLY A 407 | TAD A 901 (-2.3A)IMP A 801 ( 4.6A)TAD A 901 (-4.1A)TAD A 901 (-3.9A)NoneIMP A 801 (-3.2A) | 1.32A | 1mehA-1lrtA:58.0 | 1mehA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 7 / 10 | ASP A 261ASN A 291ILE A 313GLY A 314GLU A 408GLY A 409ARG A 414 | TAD A 901 (-2.3A)IMP A 801 ( 4.6A)TAD A 901 (-4.1A)TAD A 901 (-3.9A)NoneIMP A 801 ( 3.2A)None | 0.85A | 1mehA-1lrtA:58.0 | 1mehA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 8 / 10 | ASP A 261SER A 262SER A 263ASN A 291ILE A 313GLY A 314GLU A 408GLY A 409 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)TAD A 901 (-4.1A)TAD A 901 (-3.9A)NoneIMP A 801 ( 3.2A) | 0.30A | 1mehA-1lrtA:58.0 | 1mehA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 10 | SER A 263ASN A 291GLY A 315GLU A 408GLY A 407 | TAD A 901 (-2.7A)IMP A 801 ( 4.6A)NoneNoneIMP A 801 (-3.2A) | 1.26A | 1mehA-1lrtA:58.0 | 1mehA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEH_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 10 | SER A 263ASN A 291GLY A 359GLU A 408GLY A 407 | TAD A 901 (-2.7A)IMP A 801 ( 4.6A)IMP A 801 (-3.3A)NoneIMP A 801 (-3.2A) | 0.95A | 1mehA-1lrtA:58.0 | 1mehA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEI_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 7 / 8 | ASP A 261SER A 262SER A 263ASN A 291ILE A 313GLU A 408GLY A 409 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)TAD A 901 (-4.1A)NoneIMP A 801 ( 3.2A) | 0.33A | 1meiA-1lrtA:58.5 | 1meiA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MEI_A_MOAA600_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 4 / 8 | SER A 263ASN A 291GLU A 408GLY A 407 | TAD A 901 (-2.7A)IMP A 801 ( 4.6A)NoneIMP A 801 (-3.2A) | 0.91A | 1meiA-1lrtA:58.5 | 1meiA-1lrtA:74.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1Q8J_A_C2FA801_0 (5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINEMETHYLTRANSFERASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 12 | ARG A 299ASP A 294ILE A 313GLY A 265ILE A 292 | NoneNoneTAD A 901 (-4.1A)NoneNone | 1.32A | 1q8jA-1lrtA:6.5 | 1q8jA-1lrtA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1SDV_B_MK1B902_1 (PROTEASE RETROPEPSIN) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 10 | ALA A 334ILE A 313GLY A 314GLY A 315ILE A 311 | NoneTAD A 901 (-4.1A)TAD A 901 (-3.9A)NoneNone | 0.82A | 1sdvA-1lrtA:undetectable | 1sdvA-1lrtA:14.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AVV_A_MK1A901_1 (POL POLYPROTEIN) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 12 | ALA A 334ILE A 313GLY A 314GLY A 315ILE A 311 | NoneTAD A 901 (-4.1A)TAD A 901 (-3.9A)NoneNone | 0.81A | 2avvA-1lrtA:undetectable | 2avvA-1lrtA:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2C8A_A_NCAA1252_0 (MONO-ADP-RIBOSYLTRANSFERASE C3) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 7 | ARG A 295SER A 338ARG A 352GLU A 380 | TAD A 500 (-3.2A)TAD A 500 (-3.2A)TAD A 500 (-2.7A)TAD A 500 (-2.6A) | 0.67A | 2c8aA-3buzA:23.1 | 2c8aA-3buzA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2C8A_B_NCAB1246_0 (MONO-ADP-RIBOSYLTRANSFERASE C3) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 7 | ARG A 295SER A 338ARG A 352GLU A 380 | TAD A 500 (-3.2A)TAD A 500 (-3.2A)TAD A 500 (-2.7A)TAD A 500 (-2.6A) | 0.75A | 2c8aB-3buzA:22.9 | 2c8aB-3buzA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2C8A_C_NCAC1252_0 (MONO-ADP-RIBOSYLTRANSFERASE C3) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 6 | ARG A 295SER A 338ARG A 352GLU A 380 | TAD A 500 (-3.2A)TAD A 500 (-3.2A)TAD A 500 (-2.7A)TAD A 500 (-2.6A) | 0.61A | 2c8aC-3buzA:22.6 | 2c8aC-3buzA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2C8A_D_NCAD1247_0 (MONO-ADP-RIBOSYLTRANSFERASE C3) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 7 | ARG A 295SER A 338ARG A 352GLU A 380 | TAD A 500 (-3.2A)TAD A 500 (-3.2A)TAD A 500 (-2.7A)TAD A 500 (-2.6A) | 0.67A | 2c8aD-3buzA:18.4 | 2c8aD-3buzA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2HC4_A_VDXA525_2 (VITAMIN D RECEPTOR) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 7 | LEU A 258ILE A 337SER A 387TYR A 251 | NoneNoneNoneTAD A 500 (-4.1A) | 1.14A | 2hc4A-3buzA:undetectable | 2hc4A-3buzA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2QHF_A_ACTA502_0 (CHORISMATE SYNTHASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 3 / 3 | GLY A 265ASP A 264SER A 262 | NoneTRS A 600 ( 3.1A)TAD A 901 ( 2.6A) | 0.65A | 2qhfA-1lrtA:undetectable | 2qhfA-1lrtA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2VQY_A_PARA1201_1 (AAC(6')-IB) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 12 | GLY A 290VAL A 55SER A 63ASP A 358ASP A 261 | NoneNoneNoneIMP A 801 (-2.5A)TAD A 901 (-2.3A) | 1.42A | 2vqyA-1lrtA:0.1 | 2vqyA-1lrtA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Z54_A_AB1A200_1 (HIV-1 PROTEASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 12 | GLY A 288ASP A 261GLY A 235VAL A 247ILE A 238 | NoneTAD A 901 (-2.3A)NoneNoneNone | 0.89A | 2z54A-1lrtA:undetectable | 2z54A-1lrtA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3EM3_B_478B200_1 (PROTEASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 10 | GLY A 288ASP A 261GLY A 235VAL A 247ILE A 238 | NoneTAD A 901 (-2.3A)NoneNoneNone | 0.87A | 3em3A-1lrtA:undetectable | 3em3A-1lrtA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NDX_A_RITA100_1 (PROTEASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 12 | GLY A 288ASP A 261GLY A 235VAL A 247ILE A 238 | NoneTAD A 901 (-2.3A)NoneNoneNone | 0.96A | 3ndxA-1lrtA:undetectable | 3ndxA-1lrtA:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AF0_A_MOAA1526_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 8 | ASP A 261SER A 262SER A 263ASN A 291GLY A 409 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)IMP A 801 ( 3.2A) | 0.42A | 4af0A-1lrtA:45.3 | 4af0A-1lrtA:27.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AF0_B_MOAB1526_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 10 | ASP A 261SER A 262SER A 263ASN A 291GLY A 409 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)IMP A 801 ( 3.2A) | 0.41A | 4af0B-1lrtA:45.3 | 4af0B-1lrtA:27.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FO4_A_MOAA502_1 (INOSINE5'-MONOPHOSPHATEDEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 8 | ASP A 261SER A 262SER A 263ASN A 291CYH A 319 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)IMP A 801 (-4.0A) | 0.88A | 4fo4A-1lrtA:47.0 | 4fo4A-1lrtA:39.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FO4_A_MOAA502_1 (INOSINE5'-MONOPHOSPHATEDEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 5 / 8 | SER A 262SER A 263ASN A 291CYH A 319GLY A 409 | TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)IMP A 801 (-4.0A)IMP A 801 ( 3.2A) | 0.69A | 4fo4A-1lrtA:47.0 | 4fo4A-1lrtA:39.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FO4_B_MOAB502_1 (INOSINE5'-MONOPHOSPHATEDEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 6 / 8 | SER A 262SER A 263ASN A 291GLY A 314CYH A 319GLY A 409 | TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)TAD A 901 (-3.9A)IMP A 801 (-4.0A)IMP A 801 ( 3.2A) | 0.66A | 4fo4B-1lrtA:46.3 | 4fo4B-1lrtA:39.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FXS_A_MOAA702_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 6 / 9 | ASP A 261SER A 262SER A 263ILE A 313GLY A 314CYH A 319 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)TAD A 901 (-4.1A)TAD A 901 (-3.9A)IMP A 801 (-4.0A) | 0.97A | 4fxsA-1lrtA:46.8 | 4fxsA-1lrtA:30.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FXS_A_MOAA702_1 (INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 7 / 9 | SER A 262SER A 263ASN A 291ILE A 313GLY A 314CYH A 319ASP A 358 | TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)TAD A 901 (-4.1A)TAD A 901 (-3.9A)IMP A 801 (-4.0A)IMP A 801 (-2.5A) | 0.64A | 4fxsA-1lrtA:46.8 | 4fxsA-1lrtA:30.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4I00_A_ZMRA509_2 (NEURAMINIDASE) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 5 | LEU A 304TRP A 326ILE A 331ASN A 335 | NoneNoneNoneTAD A 500 (-2.8A) | 1.35A | 4i00A-3buzA:undetectable | 4i00A-3buzA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4M48_A_21BA704_1 (TRANSPORTER) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 4 / 8 | ASP A 264ASP A 358SER A 263ALA A 334 | TRS A 600 ( 3.1A)IMP A 801 (-2.5A)TAD A 901 (-2.7A)None | 0.88A | 4m48A-1lrtA:undetectable | 4m48A-1lrtA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XZK_A_AG2A700_1 (PUTATIVENAD(+)--ARGININEADP-RIBOSYLTRANSFERASE VIS) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 7 | ARG A 295SER A 338GLU A 378GLU A 380 | TAD A 500 (-3.2A)TAD A 500 (-3.2A)NoneTAD A 500 (-2.6A) | 0.87A | 4xzkA-3buzA:10.4 | 4xzkA-3buzA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XZK_A_AG2A700_1 (PUTATIVENAD(+)--ARGININEADP-RIBOSYLTRANSFERASE VIS) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 7 | TYR A 251ARG A 295SER A 338GLU A 380 | TAD A 500 (-4.1A)TAD A 500 (-3.2A)TAD A 500 (-3.2A)TAD A 500 (-2.6A) | 0.62A | 4xzkA-3buzA:10.4 | 4xzkA-3buzA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5F8Y_A_X6XA202_1 (GALNAC/GAL-SPECIFICLECTIN) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 4 / 8 | GLY A 314GLY A 315VAL A 293ASP A 358 | TAD A 901 (-3.9A)NoneNoneIMP A 801 (-2.5A) | 0.76A | 5f8yA-1lrtA:undetectable | 5f8yA-1lrtA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFICLECTIN) |
1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) | 4 / 8 | GLY A 314GLY A 315VAL A 293ASP A 358 | TAD A 901 (-3.9A)NoneNoneIMP A 801 (-2.5A) | 0.76A | 5f8yB-1lrtA:undetectable | 5f8yB-1lrtA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5MZR_E_PFLE409_1 (PROTON-GATED IONCHANNEL) |
3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) | 4 / 8 | PRO A 334TYR A 333THR A 332ILE A 331 | TAD A 500 (-4.6A)TAD A 500 (-4.4A)NoneNone | 0.71A | 5mzrE-3buzA:undetectable | 5mzrE-3buzA:11.30 |