SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'T44'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
7 / 11 ALA A  27
GLN A 238
LEU A 246
LEU A 248
LEU A 269
LYS A 270
ASN A 273
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 (-4.0A)
T44  A1370 (-4.8A)
T44  A1370 ( 3.3A)
0.43A 2ceoA-2xn6A:
41.3
2ceoA-2xn6A:
86.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
7 / 11 ALA A  27
GLN A 238
LEU A 246
LEU A 248
SER A 266
LEU A 269
ASN A 273
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 ( 4.1A)
T44  A1370 (-4.0A)
T44  A1370 ( 3.3A)
0.56A 2ceoA-2xn6A:
41.3
2ceoA-2xn6A:
86.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
7 / 10 ALA A  27
GLN A 238
LEU A 246
LEU A 248
LEU A 269
LYS A 270
ASN A 273
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 (-4.0A)
T44  A1370 (-4.8A)
T44  A1370 ( 3.3A)
0.43A 2ceoB-2xn6A:
41.4
2ceoB-2xn6A:
86.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
7 / 10 ALA A  27
GLN A 238
LEU A 246
LEU A 248
SER A 266
LEU A 269
ASN A 273
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 ( 4.1A)
T44  A1370 (-4.0A)
T44  A1370 ( 3.3A)
0.56A 2ceoB-2xn6A:
41.4
2ceoB-2xn6A:
86.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
7 / 10 ALA A  27
GLN A 238
LEU A 246
LEU A 248
LEU A 269
LYS A 270
ASN A 273
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 (-4.0A)
T44  A1370 (-4.8A)
T44  A1370 ( 3.3A)
0.31A 2riwA-2xn6A:
54.1
2riwB-2xn6A:
undetectable
2riwA-2xn6A:
97.97
2riwB-2xn6A:
7.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
6 / 8 GLN A 238
LEU A 246
LEU A 269
LYS A 270
ASN A 273
LEU A 276
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
T44  A1370 (-4.0A)
T44  A1370 (-4.8A)
T44  A1370 ( 3.3A)
None
0.18A 2xn3A-2xn6A:
53.6
2xn3B-2xn6A:
undetectable
2xn3A-2xn6A:
99.42
2xn3B-2xn6A:
7.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
6 / 11 GLN A 238
LEU A 246
LEU A 248
SER A 265
LEU A 269
LEU A 276
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
None
T44  A1370 (-4.0A)
None
1.18A 2xn5A-2xn6A:
53.6
2xn5A-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
8 / 11 SER A  23
ALA A  27
GLN A 238
LEU A 246
LEU A 248
LEU A 269
ASN A 273
LEU A 276
T44  A1370 (-4.3A)
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 (-4.0A)
T44  A1370 ( 3.3A)
None
0.95A 2xn5A-2xn6A:
53.6
2xn5A-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
10 / 11 SER A  23
SER A  24
ALA A  27
GLN A 238
LEU A 246
LEU A 248
LEU A 269
LYS A 270
ASN A 273
LEU A 276
T44  A1370 (-4.3A)
T44  A1370 ( 4.7A)
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 (-4.0A)
T44  A1370 (-4.8A)
T44  A1370 ( 3.3A)
None
0.48A 2xn5A-2xn6A:
53.6
2xn5A-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
10 / 11 SER A  23
SER A  24
GLN A 238
LEU A 246
LEU A 248
SER A 266
LEU A 269
LYS A 270
ASN A 273
LEU A 276
T44  A1370 (-4.3A)
T44  A1370 ( 4.7A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 ( 4.1A)
T44  A1370 (-4.0A)
T44  A1370 (-4.8A)
T44  A1370 ( 3.3A)
None
0.75A 2xn5A-2xn6A:
53.6
2xn5A-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
6 / 11 SER A  24
GLN A 238
LEU A 248
SER A 265
LEU A 269
LEU A 276
T44  A1370 ( 4.7A)
T44  A1370 (-3.3A)
None
None
T44  A1370 (-4.0A)
None
1.25A 2xn5A-2xn6A:
53.6
2xn5A-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
7 / 10 ALA A  27
GLN A 238
LEU A 246
LEU A 248
SER A 266
LEU A 269
ASN A 273
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 ( 4.1A)
T44  A1370 (-4.0A)
T44  A1370 ( 3.3A)
0.33A 2xn7A-2xn6A:
53.8
2xn7B-2xn6A:
undetectable
2xn7A-2xn6A:
99.71
2xn7B-2xn6A:
6.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
5 / 9 ALA A  27
GLN A 238
LEU A 246
LEU A 269
ASN A 273
T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
T44  A1370 (-4.0A)
T44  A1370 ( 3.3A)
0.35A 4x30A-2xn6A:
41.3
4x30A-2xn6A:
88.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
6 / 10 GLN A 238
LEU A 246
LEU A 248
SER A 265
LEU A 269
LEU A 276
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
None
T44  A1370 (-4.0A)
None
1.22A 4yiaA-2xn6A:
54.1
4yiaA-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
7 / 10 SER A  23
GLN A 238
LEU A 246
LEU A 248
LEU A 269
ASN A 273
LEU A 276
T44  A1370 (-4.3A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 (-4.0A)
T44  A1370 ( 3.3A)
None
1.12A 4yiaA-2xn6A:
54.1
4yiaA-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
8 / 10 SER A  23
SER A  24
GLN A 238
SER A 266
LEU A 269
TRP A 272
ASN A 273
LEU A 276
T44  A1370 (-4.3A)
T44  A1370 ( 4.7A)
T44  A1370 (-3.3A)
T44  A1370 ( 4.1A)
T44  A1370 (-4.0A)
None
T44  A1370 ( 3.3A)
None
0.91A 4yiaA-2xn6A:
54.1
4yiaA-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
8 / 10 SER A  24
GLN A 238
LEU A 246
LEU A 248
LEU A 269
TRP A 272
ASN A 273
LEU A 276
T44  A1370 ( 4.7A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 (-4.0A)
None
T44  A1370 ( 3.3A)
None
0.49A 4yiaA-2xn6A:
54.1
4yiaA-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
8 / 10 SER A  24
GLN A 238
LEU A 248
SER A 266
LEU A 269
TRP A 272
ASN A 273
LEU A 276
T44  A1370 ( 4.7A)
T44  A1370 (-3.3A)
None
T44  A1370 ( 4.1A)
T44  A1370 (-4.0A)
None
T44  A1370 ( 3.3A)
None
0.78A 4yiaA-2xn6A:
54.1
4yiaA-2xn6A:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo
sapiens)
5 / 10 SER A  24
LEU A 269
TRP A 272
ASN A 273
LEU A 276
T44  A1370 ( 4.7A)
T44  A1370 (-4.0A)
None
T44  A1370 ( 3.3A)
None
1.18A 4yiaA-2xn6A:
54.1
4yiaA-2xn6A:
99.71