SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'STT'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
3f81 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
3

(Homo
sapiens)
5 / 12 PHE A  77
ARG A 125
ASN A  41
GLY A 127
ARG A 158
None
None
None
STT  A   1 ( 4.5A)
None
1.25A 3aobC-3f81A:
undetectable
3aobC-3f81A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
3f81 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
3

(Homo
sapiens)
5 / 12 PHE A  77
ARG A 125
ASN A  41
GLY A 127
ARG A 158
None
None
None
STT  A   1 ( 4.5A)
None
1.29A 3aodC-3f81A:
undetectable
3aodC-3f81A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)
3f81 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
3

(Homo
sapiens)
5 / 12 GLY A 127
ILE A 160
HIS A 123
VAL A  39
VAL A  33
STT  A   1 ( 4.5A)
None
None
None
None
1.11A 5dpdA-3f81A:
undetectable
5dpdA-3f81A:
16.25