SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SSN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3q8n 4-AMINOBUTYRATE
TRANSAMINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLY A 134
VAL A 138
GLU A 139
SER A 133
VAL A 266
 SSN  A 461 (-3.4A)
None
None
SSN  A 461 (-3.8A)
SSN  A 461 (-4.9A)
 1.25A 4danA-3q8nA:
undetectable		 4danA-3q8nA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 3q8n 4-AMINOBUTYRATE
TRANSAMINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 PHE A 157
ALA A 160
TYR A 161
TYR A 178
VAL A 262
 None
None
SSN  A 461 (-4.9A)
None
None
 1.50A 6hu9N-3q8nA:
undetectable		 6hu9N-3q8nA:
22.00