SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SS2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBH_D_SAMD3293_0 (GLYCINE N-METHYLTRANSFERASE)	1zjy	R-SPECIFIC ALCOHOL DEHYDROGENASE (Lactobacillus brevis)	5 / 12	TYR A 155 GLY A 145 ALA A 157 SER A 158 TYR A 189	SS2 A1260 ( 4.2A) None None None None	1.39A	1nbhD-1zjyA: 6.9	1nbhD-1zjyA: 23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_C_SAMC2293_0 (GLYCINE N-METHYLTRANSFERASE)	1zjy	R-SPECIFIC ALCOHOL DEHYDROGENASE (Lactobacillus brevis)	5 / 12	TYR A 155 GLY A 145 ALA A 157 SER A 158 TYR A 189	SS2 A1260 ( 4.2A) None None None None	1.28A	1nbiC-1zjyA: 5.4	1nbiC-1zjyA: 23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_D_SAMD3293_0 (GLYCINE N-METHYLTRANSFERASE)	1zjy	R-SPECIFIC ALCOHOL DEHYDROGENASE (Lactobacillus brevis)	5 / 12	TYR A 155 GLY A 145 ALA A 157 SER A 158 TYR A 189	SS2 A1260 ( 4.2A) None None None None	1.27A	1nbiD-1zjyA: 5.4	1nbiD-1zjyA: 23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UBO_B_ADNB353_2 (ADENOSINE KINASE)	1zjy	R-SPECIFIC ALCOHOL DEHYDROGENASE (Lactobacillus brevis)	4 / 5	SER A 142 ILE A 18 TYR A 155 GLY A 188	NAI A1270 ( 3.8A) NAI A1270 (-3.6A) SS2 A1260 ( 4.2A) None	1.02A	3uboB-1zjyA: 6.5	3uboB-1zjyA: 21.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NBH_D_SAMD3293_0","GLYCINE N-METHYLTRANSFERASE","1zjy","R-SPECIFIC ALCOHOL DEHYDROGENASE","Lactobacillus brevis",5,"TYR A 155;GLY A 145;ALA A 157;SER A 158;TYR A 189","SS2 A1260 ( 4.2A);None;None;None;None","1.39A","1nbhD-1zjyA:6.9",null],["1NBI_C_SAMC2293_0","GLYCINE N-METHYLTRANSFERASE","1zjy","R-SPECIFIC ALCOHOL DEHYDROGENASE","Lactobacillus brevis",5,"TYR A 155;GLY A 145;ALA A 157;SER A 158;TYR A 189","SS2 A1260 ( 4.2A);None;None;None;None","1.28A","1nbiC-1zjyA:5.4","1nbhD-1zjyA:23.70"],["1NBI_D_SAMD3293_0","GLYCINE N-METHYLTRANSFERASE","1zjy","R-SPECIFIC ALCOHOL DEHYDROGENASE","Lactobacillus brevis",5,"TYR A 155;GLY A 145;ALA A 157;SER A 158;TYR A 189","SS2 A1260 ( 4.2A);None;None;None;None","1.27A","1nbiD-1zjyA:5.4","1nbiC-1zjyA:23.70"],["3UBO_B_ADNB353_2","ADENOSINE KINASE","1zjy","R-SPECIFIC ALCOHOL DEHYDROGENASE","Lactobacillus brevis",4,"SER A 142;ILE A  18;TYR A 155;GLY A 188","NAI A1270 ( 3.8A);NAI A1270 (-3.6A);SS2 A1260 ( 4.2A);None","1.02A","3uboB-1zjyA:6.5","1nbiD-1zjyA:23.70"]]