SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SRO'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1QFT_A_HSMA176_1 (PROTEIN(FEMALE-SPECIFICHISTAMINE BINDINGPROTEIN 2)) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 9 | SER A 18TYR A 27VAL A 43ASP A 106TRP A 118 | SRO A 158 (-3.6A)SRO A 158 (-3.5A)SRO A 158 ( 4.6A)SRO A 158 (-3.2A)SRO A 158 (-3.3A) | 0.40A | 1qftA-3brnA:16.1 | 1qftA-3brnA:27.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1QFT_B_HSMB176_1 (PROTEIN(FEMALE-SPECIFICHISTAMINE BINDINGPROTEIN 2)) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 9 | SER A 18TYR A 27VAL A 43ASP A 106TRP A 118 | SRO A 158 (-3.6A)SRO A 158 (-3.5A)SRO A 158 ( 4.6A)SRO A 158 (-3.2A)SRO A 158 (-3.3A) | 0.33A | 1qftB-3brnA:8.5 | 1qftB-3brnA:27.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2X45_A_HSMA1160_1 (ALLERGEN ARG R 1) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 6 | SER A 18TYR A 27VAL A 43ASP A 106TRP A 118 | SRO A 158 (-3.6A)SRO A 158 (-3.5A)SRO A 158 ( 4.6A)SRO A 158 (-3.2A)SRO A 158 (-3.3A) | 0.25A | 2x45A-3brnA:22.7 | 2x45A-3brnA:36.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2X45_B_HSMB1160_1 (ALLERGEN ARG R 1) |
3brn | LIPOCALIN (Argasmonolakensis) | 6 / 7 | SER A 18TYR A 27VAL A 43ILE A 82ASP A 106TRP A 118 | SRO A 158 (-3.6A)SRO A 158 (-3.5A)SRO A 158 ( 4.6A)SRO A 158 (-4.4A)SRO A 158 (-3.2A)SRO A 158 (-3.3A) | 0.33A | 2x45B-3brnA:22.5 | 2x45B-3brnA:36.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2X45_C_HSMC1160_1 (ALLERGEN ARG R 1) |
3brn | LIPOCALIN (Argasmonolakensis) | 6 / 7 | SER A 18TYR A 27VAL A 43ILE A 82ASP A 106TRP A 118 | SRO A 158 (-3.6A)SRO A 158 (-3.5A)SRO A 158 ( 4.6A)SRO A 158 (-4.4A)SRO A 158 (-3.2A)SRO A 158 (-3.3A) | 0.31A | 2x45C-3brnA:22.4 | 2x45C-3brnA:36.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3BU1_A_HSMA301_1 (LIPOCALIN) |
3brn | LIPOCALIN (Argasmonolakensis) | 6 / 7 | SER A 18TYR A 27VAL A 43ILE A 82ASP A 106TRP A 118 | SRO A 158 (-3.6A)SRO A 158 (-3.5A)SRO A 158 ( 4.6A)SRO A 158 (-4.4A)SRO A 158 (-3.2A)SRO A 158 (-3.3A) | 0.48A | 3bu1A-3brnA:22.3 | 3bu1A-3brnA:42.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KMO_A_EAAA214_1 (GLUTATHIONES-TRANSFERASE P) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 9 | TYR A 27VAL A 45GLY A 26ASN A 24GLY A 23 | SRO A 158 (-3.5A)NoneNoneNoneNone | 1.44A | 3kmoA-3brnA:undetectable | 3kmoA-3brnA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MBH_C_PXLC400_1 (PUTATIVEPHOSPHOMETHYLPYRIMIDINE KINASE) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 12 | ASP A 106SER A 100SER A 18TYR A 27VAL A 45 | SRO A 158 (-3.2A)NoneSRO A 158 (-3.6A)SRO A 158 (-3.5A)None | 1.46A | 3mbhC-3brnA:undetectable | 3mbhC-3brnA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MBH_E_PXLE400_1 (PUTATIVEPHOSPHOMETHYLPYRIMIDINE KINASE) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 12 | ASP A 106SER A 100SER A 18TYR A 27VAL A 45 | SRO A 158 (-3.2A)NoneSRO A 158 (-3.6A)SRO A 158 (-3.5A)None | 1.48A | 3mbhE-3brnA:undetectable | 3mbhE-3brnA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4N48_A_SAMA601_0 (CAP-SPECIFIC MRNA(NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 12 | GLY A 21PRO A 22GLY A 23ILE A 82THR A 95 | NoneNoneNoneSRO A 158 (-4.4A)SRO A 158 ( 4.1A) | 1.13A | 4n48A-3brnA:undetectable | 4n48A-3brnA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QWU_B_BO2B201_1 (PROTEASOME SUBUNITBETA TYPE-2PROTEASOME SUBUNITBETA TYPE-1) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 11 | SER A 18THR A 96THR A 95GLY A 79ALA A 15 | SRO A 158 (-3.6A)NoneSRO A 158 ( 4.1A)NoneNone | 1.39A | 4qwuV-3brnA:undetectable4qwub-3brnA:undetectable | 4qwuV-3brnA:23.774qwub-3brnA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5KR0_A_478A101_1 (PROTEASE E35D-APV) |
3brn | LIPOCALIN (Argasmonolakensis) | 5 / 9 | ALA A 15ASP A 80GLY A 53VAL A 84ILE A 82 | NoneNoneNoneNoneSRO A 158 (-4.4A) | 1.17A | 5kr0A-3brnA:undetectable | 5kr0A-3brnA:21.19 |