SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SRM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 2akj FERREDOXIN--NITRITE
REDUCTASE,
CHLOROPLAST
(Spinacia
oleracea) 		3 / 3 ARG A 309
GLY A 262
ASP A 243
 SRM  A 564 (-3.8A)
None
None
 0.46A 1kf6A-2akjA:
undetectable
1kf6B-2akjA:
undetectable		 1kf6A-2akjA:
22.42
1kf6B-2akjA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 1zj9 PROBABLE
FERREDOXIN-DEPENDENT
NITRITE REDUCTASE
NIRA
(Mycobacterium
tuberculosis) 		4 / 6 ARG A 286
GLY A 162
ASP A 163
TYR A  69
 None
None
None
SRM  A 569 (-3.4A)
 1.43A 1kf6M-1zj9A:
undetectable
1kf6N-1zj9A:
undetectable		 1kf6M-1zj9A:
22.14
1kf6N-1zj9A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 10 ARG B  87
ALA B 187
HIS B 186
ALA A 228
GLY A 313
 SRM  B 570 (-3.9A)
None
None
None
None
 1.08A 1mjqG-3mm5B:
undetectable
1mjqH-3mm5B:
undetectable		 1mjqG-3mm5B:
16.00
1mjqH-3mm5B:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 2gep SULFITE REDUCTASE
HEMOPROTEIN
(Escherichia
coli) 		5 / 12 ASP A 550
GLY A 506
ARG A 513
ILE A 514
ALA A 232
 None
None
None
None
SRM  A 580 (-4.2A)
 1.15A 1oltA-2gepA:
undetectable		 1oltA-2gepA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 4g38 SULFITE REDUCTASE
[NADPH] HEMOPROTEIN
BETA-COMPONENT
(Escherichia
coli) 		5 / 12 ASP A 550
GLY A 506
ARG A 513
ILE A 514
ALA A 232
 None
None
None
None
SRM  A 604 ( 4.2A)
 1.04A 1oltA-4g38A:
undetectable		 1oltA-4g38A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		6 / 12 ASN A 127
GLY A 182
MET A 140
LEU A 174
LEU A 162
THR A 155
 None
None
None
None
None
SRM  A 702 (-3.2A)
 1.42A 1p93C-5h8yA:
undetectable		 1p93C-5h8yA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus) 		4 / 6 GLY B 136
ILE B 138
GLN B 135
SER B 148
 SF4  B 585 ( 4.9A)
None
SRM  A 580 (-3.5A)
None
 1.02A 1rs7B-3mm5B:
undetectable		 1rs7B-3mm5B:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 12 ALA A 225
SER A 226
ALA A 233
ALA B 187
PRO B 279
 SRM  B 570 ( 4.0A)
None
None
None
None
 1.20A 2igtC-3mm5A:
undetectable		 2igtC-3mm5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		4 / 4 ASP A 334
ASP A 295
ASP A 374
GLY A 318
 None
None
None
SRM  A 702 (-3.7A)
 1.37A 2igtC-5h8yA:
undetectable		 2igtC-5h8yA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 1zj9 PROBABLE
FERREDOXIN-DEPENDENT
NITRITE REDUCTASE
NIRA
(Mycobacterium
tuberculosis) 		4 / 8 THR A 274
VAL A 243
ALA A 211
ARG A 130
 None
None
None
SRM  A 569 (-4.2A)
 1.16A 2ij7C-1zj9A:
undetectable		 2ij7C-1zj9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		5 / 12 ASN A 127
MET A 140
LEU A 174
LEU A 162
THR A 155
 None
None
None
None
SRM  A 702 (-3.2A)
 1.30A 2oaxF-5h8yA:
undetectable		 2oaxF-5h8yA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris) 		5 / 12 GLY A 137
VAL B 289
SER A 135
ASN B  99
ARG B  71
 SRM  B 503 (-4.2A)
SH0  A 503 (-3.5A)
SRM  B 503 (-2.9A)
None
SRM  B 503 (-3.0A)
 1.30A 2vmyB-2v4jA:
undetectable		 2vmyB-2v4jA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 2xsj SULFITE REDUCTASE
ALPHA SUBUNIT
(Desulfomicrobium
norvegicum) 		4 / 6 LEU A 205
ASN A 170
LYS A 215
ASP A 233
 None
None
SRM  B 503 ( 2.6A)
None
 1.31A 2w98A-2xsjA:
undetectable
2w98B-2xsjA:
undetectable		 2w98A-2xsjA:
20.70
2w98B-2xsjA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
(Desulfovibrio
gigas) 		4 / 6 LEU A 205
ASN A 170
LYS A 215
ASP A 233
 None
None
SRM  A 582 ( 2.7A)
None
 1.41A 2w98A-3or2A:
undetectable
2w98B-3or2A:
undetectable		 2w98A-3or2A:
20.80
2w98B-3or2A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus) 		5 / 12 GLU B  91
ARG B  83
PHE A 183
HIS B  33
THR B 118
 SRM  B 570 ( 4.1A)
SRM  B 570 (-2.9A)
SRM  B 570 (-3.2A)
SRM  B 570 (-3.8A)
SRM  B 570 (-4.3A)
 1.46A 2xffA-3mm5B:
undetectable		 2xffA-3mm5B:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 PRO A 222
PHE A 264
LYS A 224
 None
None
SRM  A 601 (-2.6A)
 1.07A 3bjwG-3b0hA:
undetectable		 3bjwG-3b0hA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1zj9 PROBABLE
FERREDOXIN-DEPENDENT
NITRITE REDUCTASE
NIRA
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 462
ILE A 460
ALA A 468
LEU A 425
THR A  81
 SF4  A 556 (-3.1A)
None
None
SRM  A 569 (-4.2A)
None
 1.15A 3ckkA-1zj9A:
undetectable		 3ckkA-1zj9A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		6 / 12 ASN A 127
GLY A 182
MET A 140
LEU A 174
LEU A 162
THR A 155
 None
None
None
None
None
SRM  A 702 (-3.2A)
 1.45A 3cldA-5h8yA:
undetectable		 3cldA-5h8yA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		5 / 12 ASN A 127
GLY A 182
MET A 140
LEU A 162
THR A 155
 None
None
None
None
SRM  A 702 (-3.2A)
 1.46A 3cldB-5h8yA:
undetectable		 3cldB-5h8yA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 2xsj SULFITE REDUCTASE
ALPHA SUBUNIT
(Desulfomicrobium
norvegicum) 		5 / 12 ARG A 231
GLY A 134
ALA A 175
THR A 173
LEU A 205
 SRM  B 503 (-4.0A)
SRM  B 503 (-3.3A)
None
None
None
 1.12A 3dh0B-2xsjA:
undetectable		 3dh0B-2xsjA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
SULFITE REDCUTASE
SUBUNIT BETA
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		5 / 12 ASN B 291
ALA A 235
ALA A 325
THR B  97
ILE B 289
 None
None
None
SRM  B 581 (-3.7A)
SRM  B 581 (-4.2A)
 1.24A 3dl9B-3or2B:
undetectable		 3dl9B-3or2B:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 2gep SULFITE REDUCTASE
HEMOPROTEIN
(Escherichia
coli) 		6 / 11 ASP A 227
ALA A 394
ASN A 116
GLY A  89
VAL A 221
ILE A 228
 None
None
SRM  A 580 (-3.5A)
None
None
None
 1.38A 3lzvB-2gepA:
undetectable		 3lzvB-2gepA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 4g38 SULFITE REDUCTASE
[NADPH] HEMOPROTEIN
BETA-COMPONENT
(Escherichia
coli) 		6 / 11 ASP A 227
ALA A 394
ASN A 116
GLY A  89
VAL A 221
ILE A 228
 None
None
SRM  A 604 (-3.5A)
None
None
None
 1.39A 3lzvB-4g38A:
undetectable		 3lzvB-4g38A:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Desulfovibrio
vulgaris) 		5 / 11 ASN B 191
VAL B 204
PHE B 365
ILE B 206
ARG B 366
 SRM  B 503 ( 3.5A)
None
None
None
None
 1.22A 3n23A-2v4jB:
undetectable		 3n23A-2v4jB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1zj9 PROBABLE
FERREDOXIN-DEPENDENT
NITRITE REDUCTASE
NIRA
(Mycobacterium
tuberculosis) 		4 / 5 GLN A  71
PHE A 422
TYR A 135
LEU A 425
 None
None
None
SRM  A 569 (-4.2A)
 1.45A 3sugA-1zj9A:
0.0		 3sugA-1zj9A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 11 GLY A 177
PRO A 178
GLY A 104
ARG B  83
ASP A 187
 SF4  A 575 ( 4.2A)
None
None
SRM  B 570 (-2.9A)
None
 1.41A 3t8nD-3mm5A:
undetectable
3t8nF-3mm5A:
undetectable		 3t8nD-3mm5A:
15.24
3t8nF-3mm5A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus) 		3 / 3 ARG B 277
LYS B 271
ARG B 276
 None
SRM  B 570 ( 4.1A)
SRM  B 570 (-2.6A)
 1.04A 3w1wA-3mm5B:
undetectable
3w1wB-3mm5B:
undetectable		 3w1wA-3mm5B:
20.80
3w1wB-3mm5B:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus) 		3 / 3 ARG B 276
ARG B 277
LYS B 271
 SRM  B 570 (-2.6A)
None
SRM  B 570 ( 4.1A)
 1.14A 3w1wA-3mm5B:
undetectable
3w1wB-3mm5B:
undetectable		 3w1wA-3mm5B:
20.80
3w1wB-3mm5B:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
(Desulfovibrio
vulgaris) 		3 / 3 ASP A 233
ARG A 172
LYS A 215
 None
SO3  B 504 (-2.7A)
SRM  B 503 ( 2.4A)
 1.17A 3wipG-2v4jA:
undetectable		 3wipG-2v4jA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2xsj SULFITE REDUCTASE
ALPHA SUBUNIT
(Desulfomicrobium
norvegicum) 		3 / 3 ASP A 233
ARG A 172
LYS A 215
 None
SO3  B 504 (-3.0A)
SRM  B 503 ( 2.6A)
 1.13A 3wipG-2xsjA:
undetectable		 3wipG-2xsjA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2akj FERREDOXIN--NITRITE
REDUCTASE,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 5 ILE A 230
ALA A 245
HIS A 238
ARG A 143
 None
None
None
SRM  A 564 (-4.1A)
 1.32A 4acaB-2akjA:
undetectable
4acaC-2akjA:
undetectable		 4acaB-2akjA:
22.26
4acaC-2akjA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
(Desulfovibrio
vulgaris) 		5 / 11 HIS A  98
ILE A  81
GLY A 165
GLY A 166
ASN A 170
 None
SRM  B 503 (-3.9A)
None
None
None
 1.26A 4fglA-2v4jA:
2.4
4fglB-2v4jA:
2.3		 4fglA-2v4jA:
19.05
4fglB-2v4jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2xsj SULFITE REDUCTASE
ALPHA SUBUNIT
(Desulfomicrobium
norvegicum) 		5 / 11 HIS A  98
ILE A  81
GLY A 165
GLY A 166
ASN A 170
 None
SRM  B 503 ( 4.1A)
None
None
None
 1.26A 4fglA-2xsjA:
2.3
4fglB-2xsjA:
2.4		 4fglA-2xsjA:
18.95
4fglB-2xsjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
(Desulfovibrio
gigas) 		5 / 11 HIS A  98
ILE A  81
GLY A 165
GLY A 166
ASN A 170
 None
SRM  A 582 ( 4.3A)
None
None
None
 1.22A 4fglA-3or2A:
2.2
4fglB-3or2A:
2.1		 4fglA-3or2A:
21.58
4fglB-3or2A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
(Desulfovibrio
vulgaris) 		5 / 12 SER A 169
TYR A 212
ALA A 333
ASP A 233
GLY A 168
 None
SRM  B 503 (-4.4A)
SRM  B 503 (-3.4A)
None
None
 1.15A 4iilA-2v4jA:
undetectable		 4iilA-2v4jA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 2xsj SULFITE REDUCTASE
ALPHA SUBUNIT
(Desulfomicrobium
norvegicum) 		5 / 12 SER A 169
TYR A 212
ALA A 333
ASP A 233
GLY A 168
 None
SRM  B 503 (-4.6A)
SRM  B 503 (-3.6A)
None
None
 1.17A 4iilA-2xsjA:
undetectable		 4iilA-2xsjA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
(Archaeoglobus
fulgidus) 		5 / 12 SER A 167
TYR A 210
ALA A 315
ASP A 231
GLY A 166
 None
SRM  A 580 (-4.5A)
SRM  A 580 (-3.3A)
None
None
 1.20A 4iilA-3mm5A:
undetectable		 4iilA-3mm5A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
(Desulfovibrio
gigas) 		5 / 12 SER A 169
TYR A 212
ALA A 333
ASP A 233
GLY A 168
 None
SRM  A 582 (-4.6A)
SRM  A 582 (-3.4A)
None
None
 1.19A 4iilA-3or2A:
undetectable		 4iilA-3or2A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus) 		4 / 6 GLY B 136
ILE B 138
GLN B 135
SER B 148
 SF4  B 585 ( 4.9A)
None
SRM  A 580 (-3.5A)
None
 1.00A 4kcnA-3mm5B:
undetectable		 4kcnA-3mm5B:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
(Archaeoglobus
fulgidus) 		5 / 12 PRO A 102
GLY A 134
ILE A 137
PHE A 160
LEU A 115
 None
SRM  A 580 (-4.1A)
None
None
None
 1.06A 4kosA-3mm5A:
undetectable		 4kosA-3mm5A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
(Archaeoglobus
fulgidus) 		5 / 12 PRO A 102
GLY A 134
ILE A 137
PHE A 160
LEU A 115
 None
SRM  A 580 (-4.1A)
None
None
None
 1.05A 4kotA-3mm5A:
undetectable		 4kotA-3mm5A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
(Archaeoglobus
fulgidus) 		5 / 12 PRO A 102
GLY A 134
ILE A 137
PHE A 160
LEU A 115
 None
SRM  A 580 (-4.1A)
None
None
None
 1.07A 4kovA-3mm5A:
undetectable		 4kovA-3mm5A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		4 / 6 ARG A 124
ASP A 141
GLY A 430
THR A 155
 CL  A 704 (-3.6A)
None
None
SRM  A 702 (-3.2A)
 0.93A 4l1aB-5h8yA:
undetectable		 4l1aB-5h8yA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2akj FERREDOXIN--NITRITE
REDUCTASE,
CHLOROPLAST
(Spinacia
oleracea) 		5 / 12 ILE A 148
LEU A 112
ARG A 123
THR A 141
LEU A 376
 None
None
None
SRM  A 564 (-2.9A)
None
 1.05A 4m6kA-2akjA:
undetectable		 4m6kA-2akjA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ARG A 375
GLU A 453
ARG A 149
 None
None
SRM  A 601 (-2.9A)
 0.98A 4mwvA-3b0hA:
undetectable		 4mwvA-3b0hA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3vly NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ARG A 375
GLU A 452
ARG A 149
 None
None
SRM  A 601 (-2.9A)
 0.92A 4mwvA-3vlyA:
undetectable		 4mwvA-3vlyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3or2 SULFITE REDCUTASE
SUBUNIT BETA
(Desulfovibrio
gigas) 		4 / 4 SER B 290
ASP B 339
ASP B 330
ASP B 200
 SRM  B 581 (-2.5A)
None
None
None
 1.45A 4uciA-3or2B:
0.2		 4uciA-3or2B:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3or2 SULFITE REDCUTASE
SUBUNIT BETA
(Desulfovibrio
gigas) 		4 / 4 SER B 290
ASP B 339
ASP B 330
ASP B 200
 SRM  B 581 (-2.5A)
None
None
None
 1.46A 4uciB-3or2B:
0.0		 4uciB-3or2B:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2gep SULFITE REDUCTASE
HEMOPROTEIN
(Escherichia
coli) 		5 / 12 GLY A 484
GLY A 482
ASN A 481
ALA A 394
THR A 393
 None
SF4  A 575 (-4.2A)
SRM  A 580 ( 3.5A)
None
None
 1.01A 4uckB-2gepA:
undetectable		 4uckB-2gepA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4g38 SULFITE REDUCTASE
[NADPH] HEMOPROTEIN
BETA-COMPONENT
(Escherichia
coli) 		5 / 12 GLY A 484
GLY A 482
ASN A 481
ALA A 394
THR A 393
 None
SF4  A 603 ( 4.3A)
SRM  A 604 ( 3.4A)
None
None
 1.04A 4uckB-4g38A:
undetectable		 4uckB-4g38A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Archaeoglobus
fulgidus) 		3 / 3 LYS A 300
ARG B  43
VAL B  44
 None
SRM  B 570 (-2.5A)
None
 0.96A 4x3uA-3mm5A:
undetectable
4x3uB-3mm5A:
undetectable		 4x3uA-3mm5A:
8.61
4x3uB-3mm5A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3or2 SULFITE REDCUTASE
SUBUNIT BETA
(Desulfovibrio
gigas) 		4 / 5 GLU B 109
THR B 110
HIS B  44
LEU B  47
 None
None
SRM  B 581 (-3.8A)
None
 0.98A 5axaA-3or2B:
undetectable		 5axaA-3or2B:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3or2 SULFITE REDCUTASE
SUBUNIT BETA
(Desulfovibrio
gigas) 		4 / 5 GLU B 109
THR B 110
HIS B  44
LEU B  47
 None
None
SRM  B 581 (-3.8A)
None
 0.99A 5axaC-3or2B:
undetectable		 5axaC-3or2B:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3or2 SULFITE REDCUTASE
SUBUNIT BETA
(Desulfovibrio
gigas) 		4 / 6 SER B 140
GLY B 338
ASP B 339
GLY B 287
 SRM  B 581 (-2.7A)
None
None
None
 0.94A 5cdnC-3or2B:
2.8
5cdnD-3or2B:
undetectable		 5cdnC-3or2B:
19.77
5cdnD-3or2B:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2xsj SULFITE REDUCTASE
ALPHA SUBUNIT
SULFITE REDUCTASE
BETA SUBUNIT
(Desulfomicrobium
norvegicum) 		5 / 12 THR B  64
THR B 135
GLN B 181
THR B  96
CYH A 225
 None
SRM  A 503 (-4.2A)
None
SRM  A 503 (-2.8A)
SF4  A 502 ( 2.2A)
 1.42A 5d0xH-2xsjB:
undetectable
5d0xI-2xsjB:
undetectable		 5d0xH-2xsjB:
21.48
5d0xI-2xsjB:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_F_EVPF102_1
(DNA TOPOISOMERASE
2-ALPHA)		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Desulfovibrio
vulgaris) 		4 / 5 GLY A 330
ASP A 233
ARG A 378
MET B 284
 None
None
SRM  B 503 (-2.9A)
None
 1.03A 5gwkA-2v4jA:
undetectable		 5gwkA-2v4jA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_F_EVPF102_1
(DNA TOPOISOMERASE
2-ALPHA)		 2xsj SULFITE REDUCTASE
ALPHA SUBUNIT
SULFITE REDUCTASE
BETA SUBUNIT
(Desulfomicrobium
norvegicum) 		4 / 5 GLY A 330
ASP A 233
ARG A 378
MET B 289
 None
None
SRM  B 503 (-2.9A)
None
 1.08A 5gwkA-2xsjA:
2.0		 5gwkA-2xsjA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 2gep SULFITE REDUCTASE
HEMOPROTEIN
(Escherichia
coli) 		5 / 10 LEU A 398
ALA A 103
PHE A 122
THR A 119
LEU A 137
 None
None
None
SRM  A 580 (-4.2A)
None
 1.09A 5mm4B-2gepA:
undetectable		 5mm4B-2gepA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 4g38 SULFITE REDUCTASE
[NADPH] HEMOPROTEIN
BETA-COMPONENT
(Escherichia
coli) 		5 / 10 LEU A 398
ALA A 103
PHE A 122
THR A 119
LEU A 137
 None
None
None
SRM  A 604 (-4.2A)
None
 1.08A 5mm4B-4g38A:
undetectable		 5mm4B-4g38A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		5 / 12 VAL A 113
LEU A 166
ARG A 509
PRO A 498
LEU A 499
 None
None
None
None
SRM  A 702 ( 4.7A)
 1.26A 5nd2B-5h8yA:
undetectable		 5nd2B-5h8yA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
(Desulfovibrio
gigas) 		4 / 6 THR A 162
ASP A 163
LEU A 102
ASP A 138
 None
None
None
SRM  A 582 (-3.8A)
 0.94A 5tdzA-3or2A:
undetectable		 5tdzA-3or2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2xsj SULFITE REDUCTASE
BETA SUBUNIT
(Desulfomicrobium
norvegicum) 		4 / 8 TRP B  41
TYR B  63
THR B  64
ARG B  94
 None
None
None
SRM  A 503 (-2.7A)
 1.38A 5tzoA-2xsjB:
undetectable		 5tzoA-2xsjB:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2xsj SULFITE REDUCTASE
BETA SUBUNIT
(Desulfomicrobium
norvegicum) 		4 / 8 TRP B  41
TYR B  63
THR B  64
ARG B  94
 None
None
None
SRM  A 503 (-2.7A)
 1.39A 5tzoB-2xsjB:
undetectable		 5tzoB-2xsjB:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2xsj SULFITE REDUCTASE
BETA SUBUNIT
(Desulfomicrobium
norvegicum) 		4 / 8 TRP B  41
TYR B  63
THR B  64
ARG B  94
 None
None
None
SRM  A 503 (-2.7A)
 1.36A 5tzoC-2xsjB:
undetectable		 5tzoC-2xsjB:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 1zj9 PROBABLE
FERREDOXIN-DEPENDENT
NITRITE REDUCTASE
NIRA
(Mycobacterium
tuberculosis) 		4 / 8 GLY A 479
GLU A 491
ILE A 460
GLN A 379
 None
None
None
SRM  A 569 (-3.9A)
 1.02A 5vlmD-1zj9A:
undetectable		 5vlmD-1zj9A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3or2 SULFITE REDCUTASE
SUBUNIT BETA
(Desulfovibrio
gigas) 		5 / 12 ARG B 336
GLY B 338
GLY B 202
SER B 199
ILE B 201
 SRM  B 581 (-3.0A)
None
None
None
None
 1.17A 5vooA-3or2B:
undetectable		 5vooA-3or2B:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		5 / 12 GLY A 543
GLY A 318
GLY A 320
ALA A 333
ASP A 290
 SF4  A 701 (-4.4A)
SRM  A 702 (-3.7A)
SRM  A 702 (-3.5A)
None
None
 1.12A 5x7fA-5h8yA:
undetectable		 5x7fA-5h8yA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris) 		4 / 6 SER A 235
ARG B 183
ARG A 231
ASP A 219
 None
SH0  A 503 (-3.8A)
SRM  B 503 (-4.1A)
SF4  A 501 ( 4.8A)
 1.11A 5zw4A-2v4jA:
undetectable		 5zw4A-2v4jA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris) 		5 / 12 HIS B 152
GLY B 147
ALA B 158
ILE B 190
PRO A 334
 SRM  B 503 (-4.5A)
None
None
None
None
 1.10A 6b3aA-2v4jB:
undetectable		 6b3aA-2v4jB:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
SULFITE REDCUTASE
SUBUNIT BETA
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		5 / 12 HIS B 152
GLY B 147
ALA B 158
ILE B 190
PRO A 334
 SRM  A 582 (-4.4A)
None
None
None
None
 1.09A 6b3aA-3or2B:
undetectable		 6b3aA-3or2B:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA
(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris) 		5 / 12 HIS B 152
GLY B 147
ALA B 158
ILE B 190
PRO A 334
 SRM  B 503 (-4.5A)
None
None
None
None
 1.11A 6b3bA-2v4jB:
undetectable		 6b3bA-2v4jB:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC
(Zea
mays) 		4 / 7 ASP A 295
GLN A 355
GLY A 320
GLY A 318
 None
None
SRM  A 702 (-3.5A)
SRM  A 702 (-3.7A)
 0.90A 6ekzA-5h8yA:
undetectable		 6ekzA-5h8yA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
(Desulfovibrio
gigas) 		4 / 7 ASP A 138
GLN A 104
LYS A 108
LYS A 217
 SRM  A 582 (-3.8A)
None
None
SRM  A 582 (-2.7A)
 1.50A 6g31A-3or2A:
2.4		 6g31A-3or2A:
12.09