SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SQS'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D91_B_REMB350_1 (RENIN)	3vzb	SPHINGOSINE KINASE 1 (Homo sapiens)	5 / 12	GLN A 128 GLY A  80 ASP A  81 ALA A 115 SER A 168	None None None SQS  A 401 ( 4.8A) SQS  A 401 (-3.1A)	1.19A	3d91B-3vzbA: undetectable	3d91B-3vzbA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E9R_A_ACTA700_0 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	3vzb	SPHINGOSINE KINASE 1 (Homo sapiens)	4 / 6	GLY A 113 GLU A 189 GLY A 269 MET A 272	SQS  A 401 ( 4.2A) None None SQS  A 401 (-3.5A)	0.96A	3e9rA-3vzbA: undetectable	3e9rA-3vzbA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E9R_C_ACTC700_0 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	3vzb	SPHINGOSINE KINASE 1 (Homo sapiens)	4 / 6	GLY A 113 GLU A 189 GLY A 269 MET A 272	SQS  A 401 ( 4.2A) None None SQS  A 401 (-3.5A)	0.96A	3e9rC-3vzbA: undetectable	3e9rC-3vzbA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G2O_A_SAMA500_0 (PCZA361.24)	3vzb	SPHINGOSINE KINASE 1 (Homo sapiens)	5 / 12	GLY A 113 LEU A 268 LEU A  83 SER A 168 GLU A 343	SQS  A 401 ( 4.2A) SQS  A 401 (-4.4A) None SQS  A 401 (-3.1A) None	1.03A	3g2oA-3vzbA: undetectable	3g2oA-3vzbA: 24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UDA_A_DEXA1985_2 (MINERALOCORTICOID RECEPTOR)	3vzb	SPHINGOSINE KINASE 1 (Homo sapiens)	4 / 6	LEU A 259 PHE A 303 THR A 196 VAL A 177	None None SQS  A 401 ( 4.3A) SQS  A 401 ( 4.5A)	1.09A	4udaA-3vzbA: undetectable	4udaA-3vzbA: 24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_A_BEZA1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	3vzb	SPHINGOSINE KINASE 1 (Homo sapiens)	4 / 6	GLY A 195 THR A 196 SER A 181 VAL A 177	None SQS  A 401 ( 4.3A) None SQS  A 401 ( 4.5A)	0.87A	5ewuA-3vzbA: undetectable	5ewuA-3vzbA: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKR_A_ID8A601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3vzb	SPHINGOSINE KINASE 1 (Homo sapiens)	5 / 12	LEU A 263 GLY A 269 ALA A 115 SER A 119 LEU A 116	None None SQS  A 401 ( 4.8A) None None	1.05A	5ikrA-3vzbA: undetectable	5ikrA-3vzbA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_S_PCFS603_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 8 CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL)	3vzb	SPHINGOSINE KINASE 1 (Homo sapiens)	4 / 7	GLY A  82 HIS A  85 VAL A  88 SER A 168	None None None SQS  A 401 (-3.1A)	0.94A	6hu9S-3vzbA: undetectable 6hu9q-3vzbA: undetectable	6hu9S-3vzbA: 12.36 6hu9q-3vzbA: 14.44